Journal of the Korean Association of Oral and Maxillofacial Surgeons

The Korean Association of Oral and Maxillofacial Surgeons (대한구강악안면외과학회)
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A CASE REPORT OF KIMURA'S DISEASE IN THE PAROTID REGION

이하선부에 발생한 Kimura's disease에 대한 치험례

  • Byun, Sung-Soo (Department of Oral and Maxillofacial Surgery, College of Dentistry, Yonsei University) ;
  • Jung, Hwui-Dong (Department of Oral and Maxillofacial Surgery, College of Dentistry, Yonsei University) ;
  • Choi, Young-Dal (Department of Oral and Maxillofacial Surgery, College of Dentistry, Yonsei University) ;
  • Kim, Hyun-Sil (Department of Oral Pathology, College of Dentistry, Yonsei University) ;
  • Cha, In-Ho (Department of Oral and Maxillofacial Surgery, College of Dentistry, Yonsei University) ;
  • Kim, Hyung-Jun (Department of Oral and Maxillofacial Surgery, College of Dentistry, Yonsei University)
  • 변성수 (연세대학교 치과대학 구강악안면외과학교실) ;
  • 정휘동 (연세대학교 치과대학 구강악안면외과학교실) ;
  • 최영달 (연세대학교 치과대학 구강악안면외과학교실) ;
  • 김현실 (연세대학교 치과대학 구강병리학교실) ;
  • 차인호 (연세대학교 치과대학 구강악안면외과학교실) ;
  • 김형준 (연세대학교 치과대학 구강악안면외과학교실)
  • Published : 2007.10.31
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Abstract

Kimura's disease is a chronic inflammatory disorder presenting regional lymphadenopathy with painless soft tissue mass. Clinically, peripheral eosinophilia and elevated serum IgE levels are observed, and proteinuria associated with renal disease can also be present. Although its etiology is not clearly understood, it occurs predominantly in young Asian males and presents as a deep, subcutaneous mass involving salivary glands of the preauricular and submandibular regions. Spontaneous remission is very rare, and although treatments such as steroid, cytotoxic therapy and irradiation are available, chronic recurrence is very common. As such, surgical excision is regarded as the mainstay of therapy for localized lesions. Histopathologically, Kimura's disease features eosinophilic abscsesses and dense lymphoid aggregates with germinal center. Clinical differential diagnosis of Kimura's disease from other parotid diseases with accompanying lymphadenopathy is often very challenging prior to biopsy. The authors report a case of a 19-year-old male diagnosed with Kimura's disease in the parotid region who underwent surgical excision and was followed up for 6 years, along with a review of related literature.

저자 등은 좌측 이하부에 발생한 기무라씨병을 가진 19세의 남환에 대하여 표층 이하선 절제술을 동반한 종양 절제술과 함께 방사선 치료를 시행하였다. 수술 후 약 6년 9개월 경과 관찰 한 결과 현재까지 특기할만한 후유증 및 합병증과 재발 소견 혹은 증상은 보이지 않았기에 문헌 고찰과 함께 보고하는 바이며, 이후에도 지속적인 경과관찰을 요하리라 사료된다.

Keywords

References

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