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Comprehensive review of membranoproliferative glomerulonephritis: spotlighting the latest advances in revised classification and treatment

  • Jeong Yeon Kim
    • Childhood Kidney Diseases
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    • v.27 no.2
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    • pp.64-69
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    • 2023
  • Membranoproliferative glomerulonephritis (MPGN) is a complex group of renal diseases characterized by a specific pattern of glomerular injury that includes thickening of the capillary wall and mesangial expansion, leading to a heterogeneous group of conditions. This review article offers a comprehensive overview of MPGN, its new classification, pathophysiology, diagnostic evaluation, and management options.

Diagnosis and Treatment of Nontuberculous Mycobacterial Lung Disease: Clinicians' Perspectives

  • Ryu, Yon Ju;Koh, Won-Jung;Daley, Charles L.
    • Tuberculosis and Respiratory Diseases
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    • v.79 no.2
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    • pp.74-84
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    • 2016
  • Nontuberculous mycobacteria (NTM) are emerging pathogens that affect both immunocompromised and immunocompetent patients. The incidence and prevalence of NTM lung disease are increasing worldwide and rapidly becoming a major public health problem. For the diagnosis of NTM lung disease, patients suspected to have NTM lung disease are required to meet all clinical and microbiologic criteria. The development of molecular methods allows the characterization of new species and NTM identification at a subspecies level. Even after the identification of NTM species from respiratory specimens, clinicians should consider the clinical significance of such findings. Besides the limited options, treatment is lengthy and varies by species, and therefore a challenge. Treatment may be complicated by potential toxicity with discouraging outcomes. The decision to start treatment for NTM lung disease is not easy and requires careful individualized analysis of risks and benefits. Clinicians should be alert to those unique aspects of NTM lung disease concerning diagnosis with advanced molecular methods and treatment with limited options. Current recommendations and recent advances for diagnosis and treatment of NTM lung disease are summarized in this article.

Pediatric Mechanical Circulatory Support

  • Wilmot, Ivan;Lorts, Angela;Morales, David
    • Journal of Chest Surgery
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    • v.46 no.6
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    • pp.391-401
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    • 2013
  • Mechanical circulatory support (MCS) in the pediatric heart failure population has a limited history especially for infants, and neonates. It has been increasingly recognized that there is a rapidly expanding population of children diagnosed and living with heart failure. This expanding population has resulted in increasing numbers of children with medically resistant end-stage heart failure. The traditional therapy for these children has been heart transplantation. However, children with heart failure unlike adults do not have symptoms until they present with end-stage heart failure and therefore, cannot safely wait for transplantation. Many of these children were bridged to heart transplantation utilizing extracorporeal membranous oxygenation as a bridge to transplant which has yielded poor results. As such, industry, clinicians, and the government have refocused interest in developing increasing numbers of MCS options for children living with heart failure as a bridge to transplantation and as a chronic therapy. In this review, we discuss MCS options for short and long-term support that are currently available for infants and children with end-stage heart failure.

An Analytical Study of National and International Care Label Systems of Textile and Apparel Products

  • Sanad, Reham A.;Kang, Zi Young
    • Fashion & Textile Research Journal
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    • v.20 no.3
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    • pp.331-342
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    • 2018
  • This paper enables stakeholders involved in textile industry to gain an overview of standards used for care labelling and help establish a common standard that could be used as a universal standard. This study provides a comprehensive and detailed analytical study of care labelling standards adopted by common countries in the textile market. It was found that the development of a universal system for care labeling could enhance the trade of textile articles and assist consumers in caring for textile articles. Universal care label systems could be characterized by two main features of inclusiveness and comprehensiveness. The range of instructions and symbols presented were found different among standards. Insignificant differences in symbols' shapes were found between standards for bleaching, ironing and professional cleaning. The washing process had the widest variety of instructions; in addition, options were provided by stated standards. Different meanings were found for similar shapes in some tumble drying symbols. The study findings show the importance of enhancing text based standards or the development of an understandable format across as many cultures as possible. The unification of symbols and meanings may be needed to provide global consumers consistent guidance. The efficiency of a detailed standard that provides and covers a wide range of instructions is an important aspect. The visibility and practicality of offering variable options/symbols in one standard is an important aspect for developing a universal care label system.

Fertility preservation during cancer treatment: The Korean Society for Fertility Preservation clinical guidelines

  • Kim, Jayeon;Kim, Seul Ki;Hwang, Kyung Joo;Kim, Seok Hyun
    • Clinical and Experimental Reproductive Medicine
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    • v.44 no.4
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    • pp.171-174
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    • 2017
  • While many fertility preservation (FP) options now exist for reproductive-aged cancer patients, access to these services continues to be limited. A comprehensive FP program should be organized to serve oncofertility patients effectively. Also, much effort is needed from various individuals-patients, specialists from various fields, and consultants-to facilitate FP in a timely manner. Various challenges still exist in improving access to FP programs. To improve access to FP treatment, it is important to educate oncologists and patients via electronic tools and to actively navigate patients through the system. Reproductive endocrinology practices that receive oncofertility referrals must be equipped to provide a full range of options on short notice. A multidisciplinary team approach is required, involving physicians, nurses, mental health professionals, office staff, and laboratory personnel. The bottom line of FP patient care is to understand the true nature of each patient's specific situation and to develop a patient flow system that will help build a successful FP program. Expanding the patient flow system to all comprehensive cancer centers will ensure that all patients are provided with adequate information regarding their fertility, regardless of geography.

A simulation analysis of PV application method effect on electric power performance in an apartment wall facade (아파트 입면형 PV적용방식의 발전성능효과해석 연구)

  • Seo, Jung-Hun;Huh, Jung-Ho
    • Journal of the Korean Solar Energy Society
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    • v.26 no.3
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    • pp.25-32
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    • 2006
  • The objective of this study is to investigate the effect of building integrated PV application method on power generation. PV modules were integrated to a hypothetical apartment building facade in Seoul, Korea. Three different design options of PV panel mounted on exterior wall were developed for the analysis of cooling effects through ventilation. Numerical simulations using TRNSYS coupled with COMIS were executed to evaluate the design options. Their facade configurations are such as vertically installed PV panels with or without air gap between PV rear surface and exterior wall surface, and the tilted PV panels attached to the exterior wall at an angle of to the horizontal. Parametric results show that there is little difference regardless of the air 9ap width between PV rear surface and exterior wall surface. Special strategies which could effectively cool a PV panel to increase the electric power are required if we prefer to a vertical facade configuration in a building integrated PV installation. Consequently, it is expected that there is no reason for architect to install vertically PV panels with air gap unless active strategies are considered.

Treasury Bond Futures Option Prices as.Predictors of Equilibrium Futures Prices (균형(均衡)퓨처가격(價格)(equilibrium futures prices)을 예측하기 위한 재무성(財務省) 장기채권(長期債券)(Treasury bond)의 퓨처옵션가격(價格)(futures option prices)에 대한 연구(硏究))

  • Kim, Won-Kee
    • The Korean Journal of Financial Management
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    • v.8 no.1
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    • pp.199-212
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    • 1991
  • 주식옵션(stock options)에 대한 연구에 비교하여 상품 및 퓨처 옵션(commodity & futures options)에 대한 연구는 선진국에서도 지금 한참 연구를 하고 있는 단계에 있다. 우리나라에서도 이 분야에 대한 이론을 바탕으로 하는 제도를 곧 도입하려는 준비를 하고 있다. 본 연구는 블랙의 '블랙의 컴모디티 옵션의 가격모형(Black commodity option pricing model)'을 이용하여 재무성 장기채권의 퓨처의 균형가격을 예측하는데 있다. 이 블랙모형의 적용가능성을 검증해 본 것이다. 실제퓨처가격(observed futures prices)과는 달리 재무성 장기채권 퓨처 옵션에서의 묵시적 퓨처가격(futures prices implicit)은 시장효율성(market efficiencies)의 전제하에 성립되거나, 아니면 옵션가격모형을 사용하여서는 아니되거나 둘 중의 하나이거나 둘 다 섞이거나 일 것이다. 본 실증적인 연구, 즉 묵시적인 표준편차(implied standard deviations)를 사이멀테니어스(simultaneously)하게 계산한 묵시적인 퓨처가격(implied futures prices)을 사용한 실증적인 연구는 옵션모델에 의하여 퓨처가격을 계산하는 데에 문제가 있음을 발견하였다. 그 이유는 옵션가격결정모형을 이용하여 계산한 재무성 장기채권의 퓨쳐가격은 재무성 장기채권의 미래가격변동의 방향을 제시하는 지표로써 사용할 수 없기 때문일 것이다. 우리나라에서도 이 분야에 대한 이론과 제도를 곧 도입하는 입장에서 선행되는 문헌이 될 것이다.

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