• Title/Summary/Keyword: Option values

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Bayesian Value of Information Analysis with Linear, Exponential, Power Law Failure Models for Aging Chronic Diseases

  • Chang, Chi-Chang
    • Journal of Computing Science and Engineering
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    • v.2 no.2
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    • pp.200-219
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    • 2008
  • The effective management of uncertainty is one of the most fundamental problems in medical decision making. According to the literatures review, most medical decision models rely on point estimates for input parameters. However, it is natural that they should be interested in the relationship between changes in those values and subsequent changes in model output. Therefore, the purpose of this study is to identify the ranges of numerical values for which each option will be most efficient with respect to the input parameters. The Nonhomogeneous Poisson Process(NHPP) was used for describing the behavior of aging chronic diseases. Three kind of failure models (linear, exponential, and power law) were considered, and each of these failure models was studied under the assumptions of unknown scale factor and known aging rate, known scale factor and unknown aging rate, and unknown scale factor and unknown aging rate, respectively. In addition, this study illustrated developed method with an analysis of data from a trial of immunotherapy in the treatment of chronic Granulomatous disease. Finally, the proposed design of Bayesian value of information analysis facilitates the effective use of the computing capability of computers and provides a systematic way to integrate the expert's opinions and the sampling information which will furnish decision makers with valuable support for quality medical decision making.

Effects of Inspiration and Expiration Exercise Combined with Upper Extremity Proprioceptive Neuromuscular Facilitation on Forced Volume Vital and Peak Expiratory Flow

  • Lee, Sang-Yeol
    • PNF and Movement
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    • v.18 no.2
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    • pp.297-303
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    • 2020
  • Purpose: The purpose of this study was to examine the effects of inhalation and exhalation exercise combined with upper extremity proprioceptive neuromuscular facilitation pattern on two spirometry values: forced volume vital (FVC) and peak expiratory flow (PEF). Methods: Thirty-two healthy adults were divided into two groups: 1) a combined group, which performed upper extremity D2 flexion pattern (shoulder flexed/abducted/external rotated, forearm supinated, wrist radial deviated, and finger extended) during exhalation and D2 extension pattern (shoulder extended/adducted/internal rotated, forearm pronated, wrist ulnar deviated, and finger flexed) during inhalation; and 2) reverse combined group, which performed the D2 flexion pattern during inhalation and the D2 extension pattern during exhalation. The inverse application of upper extremity movements during inhalation and exhalation induced selective resistance or assistance on respiration. FVC and PEF were measured at two time points, before and after four weeks. Results: In both groups, the pre-post intervention comparison showed significant increases in FVC and PEF (p < .05). In the between-groups comparison, the reverse combined group showed a significantly higher PEF than the combined group at four weeks post intervention (p < 0.05). Conclusion: The combined respiration exercise with reverse PNF upper extremity patterns using selective resistance showed an effective increase in PEF in healthy adults. Clinicians and researchers might consider using selective resistance as a widely applicable and cost-effective option for respiratory rehabilitation planning.

Profit analysis of life insurance products with interest rate options (이자율 보증옵션이 내재된 생명보험의 이차익 분석)

  • Lee, Hangsuck
    • Journal of the Korean Data and Information Science Society
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    • v.24 no.4
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    • pp.737-753
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    • 2013
  • Interest rate options embedded in life insurance products provide policyholders with minimum guaranteed rates credited to the corresponding surrender values. This paper discusses current low-interest environment and several types of interest rate options embedded in life insurance products. In addition, this paper shows profit structures of the life insurance products and calculates values of the interest rate options under stochastic interest model and the corresponding VaR (value at risk). Finally, some implications are discussed.

Oblique Single-Cut Rotation Osteotomy for Correction of Femoral Varus-Torsional Deformities in 3D-Reconstructed Canine Bone Models

  • Kim, Hyeon-Ho;Roh, Yoon-Ho;Lee, Je-Hun;Jeong, Jae-Min;Jeong, Seong Mok;Lee, Hae Beom
    • Journal of Veterinary Clinics
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    • v.37 no.4
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    • pp.180-184
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    • 2020
  • The purpose of this study was to report the reliability and validity of oblique single-cut rotation osteotomy (OSCRO) in 3D-reconstructed canine bone models with femoral varus and torsional deformities. A healthy adult male beagle was recruited to create a 3D bone model, and this bone model was modified by using a 3D program. Fifteen bone models were constructed for this study. OSCRO simulation was performed in accordance with the plan after printing using a 3D printing machine. The anatomical lateral distal femoral angle (aLDFA), anteversion angle (AA), anatomical caudo-distal femoral angle (aCdDFA), mechanical caudo-distal femoral angle (mCdDFA) and pre- and postoperative bone length were calculated. There were no significant differences between the target values and postoperative values. In addition, the difference between pre- and postoperative bone length was small (p = 0.001). Our findings suggest that OSCRO could be an effective surgical option for MPL with bone deformities in small-breed dogs that often undergo conventional distal femoral osteotomy.

Evaluation of two interforaminal implants and implant-assisted removable dentures on stress distribution: an in vitro study

  • Bilhan, Selda Arat;Geckili, Onur;Cilingir, Altug;Bozdag, Ergun;Bilhan, Hakan
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.45 no.4
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    • pp.199-206
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    • 2019
  • Objectives: In mandibular edentulism, the treatment option with a two-interforaminal implant-retained bridge and a removable partial denture is rarely evaluated in literature. The aim of this in vitro study was to evaluate the stress distribution of this treatment option by comparing it with traditional treatment options with interforaminal implants in the edentulous mandible. Materials and Methods: Two interforaminal implants were placed in a formalin-fixed cadaver mandible, and overdentures with three different types of attachments were fabricated: (1) two ball attachments and an overdenture, (2) a Dolder bar and an overdenture, and (3) screw-retained two-implant inter-canine porcelain fused to a metal bridge and an implant-assisted removable denture (IARD) with precision attachments. Three biting conditions were generated for each denture type, and the strains were documented under vertical loading of 100 N. Results: The calculated strain values from measured strains in all measurement sites and loading conditions for the screw-retained two-implant intercanine porcelain fused to a metal bridge and a cast framework partial denture with precision attachments situation were lower than in the other scenarios (P<0.05). Conclusion: Within the limitations of the present study, it can be concluded that an IARD may be a reasonable and valuable alternative to ball attachments or a bar in two interforaminal implants, especially when the patients prefer to be able to show their teeth even when they take out their removable dentures.

Energy Saving Effects of Green Roof in Exiting Buildings according to Different Insulation Levels (기존 노후 건물의 단열 성능에 따른 옥상 녹화 시스템 설치시 에너지 성능 변화)

  • An, Kyeong A;Han, Seung Won;Moon, Hyeun Jun
    • Journal of Korean Living Environment System
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    • v.21 no.6
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    • pp.959-964
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    • 2014
  • Energy performance of building envelope components, including external walls, floors, roofs, windows and doors, is crutial for determining how much energy is required for heating and cooling in a building. Among various building technologies, a green roof system can be a good option for reducing heat gain and loss in new buildings as well as existing buildings for green remodeling. This paper evaluates the performance of green roof systems according to soil depth and Leaf Area Index (LAI) for existing buildings. It also attempts to quantify the energy saving effects on new and existing buildings with different insulation levels. Thermal performance of green roofs is mainly dependent on soil thickness and LAI. Installation of green roofs in deteriorated existing buildings can lead to improvements in roof insulation, due to the soil layer. An increase in soil depth leads to a decrease in heating load, regardless of conditions of vegetation on the green roof. Larger LAI values may reduce cooling loads in the cooling season. Installation of green roof in deteriorated existing buildings showed bigger energy saving effect in comparison to a case in new buildings. A simulation study showed that the installation of green roof systems in deteriorated existing buildings with low insulation levels, due to low thermal performance requirements when constructed, could improve the energy performance of the buildings similar or better to the peformance on new buildings with the most updated insulation standard. Thus, when remodeling a deteriorated building, green roofs could be a good option to meet the most recent energy requirements.

A Selective Induction Framework for Improving Prediction in Financial Markets

  • Kim, Sung Kun
    • Journal of Information Technology Applications and Management
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    • v.22 no.3
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    • pp.1-18
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    • 2015
  • Financial markets are characterized by large numbers of complex and interacting factors which are ill-understood and frequently difficult to measure. Mathematical models developed in finance are precise formulations of theories of how these factors interact to produce the market value of financial asset. While these models are quite good at predicting these market values, because these forces and their interactions are not precisely understood, the model value nevertheless deviates to some extent from the observable market value. In this paper we propose a framework for augmenting the predictive capabilities of mathematical model with a learning component which is primed with an initial set of historical data and then adjusts its behavior after the event of prediction.

A Study on the Assessment Method of Noise Exposure Population Using the Over-ride value Noise map (Over-ride Value소음지도를 이용한 소음노출인구 산정방법 연구)

  • Park, In-Sun;Park, Sang-Kyu
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2005.05a
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    • pp.911-916
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    • 2005
  • Noise map is a presentation of existing data or predicted noise situation in terms of noise indicator. However, it has shortcoming for assessing the number of people exposed, or the number of dwellings affected to any relevant limit values of noise level in certain areas. In this study, so called over-ride value noise mapping is proposed to make up for the shortcoming by using over-ride function of object-oriented programming and it is to show the guard of the area where it is satisfied the standard of option, or it is not satisfactory. Over-ride value noisemap data is combined with topography layer, population and house statistics, and GIS space statistical analysis. The over-ride value noise mapping can also he applied to make the road traffic noisemap, the railroad noisemap, the aircraft noisemap, and the industrial site noisemap This can express noise damage information more exactly.

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Hyperprolactinemia and Galactorrhea Following Single Epidural Steroid Injection (경막외강내 스테로이드 투여후 관찰된 혈중 Prolactin 증가와 유즙 분비 -증례 보고-)

  • Won, Seog-Kyu;Chun, Yong-Suk;Suk, Min-Ho;Shim, Jae-Chol
    • The Korean Journal of Pain
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    • v.11 no.1
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    • pp.150-154
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    • 1998
  • Epidural steroid injection have become one of the most frequently applied conservative option for the management of acute and chronic back pain. As the indications for epidural steroid injections increase so do the adverse responses associated with this procedure. This study reports the succession of 3 patients who developed galactorrhea and hyperprolactinemia after recieving an epidural steroid injection for lumbar radiculopathy and low back pain. Serum prolactin level was elevated in accordance with epidural injection of corticosteroid. We measured the serum prolactin level by immunoradiometric assay method and peak serum prolactin level at above 500, 144.2, 150.3 ng/ml respectively. Also we found the serum prolactin level decreased to normal values 3 wks after corticosteroid injection. Galactorrhra ceased in advance of decrease of serum prolactin level. That "Hyperprolactinemia and galactorrhea can occur following epidural steroid injection", requires a much larger prospective investigation.

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Foreign Exchange Risk Control in the Context of Supply Chain Management

  • Park, Koo-Woong
    • Journal of Distribution Science
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    • v.13 no.2
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    • pp.15-24
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    • 2015
  • Purpose - Foreign exchange risk control is in an important component in the international supply chain management. This study shows the importance of the reference period in forecasting future exchange rates with a specific illustration of KIKO currency option contracts, and suggests feasible preventive measures. Research design, data, and methodology - Using monthly Won-Dollar exchange rate data for January 1995~July 2007, I evaluate the statistical characteristics of the exchange rate for two sub-periods; 1) a shorter period after the East Asian financial crisis and 2) a longer period including the financial crisis. The key instrument of analysis is the basic normal distribution theory. Results - The difference in the reference period could lead to an unexpected development in contract implementation and a consequent financial loss. We may avoid foreign exchange loss by using derivatives such as forwards or currency options. Conclusions - We should consider not only level values but also the volatilities of financial variables in making a binding financial contract. Appropriate measures may differ depending on the specific supply chain pattern. We may extend the study with surveys on actual risk measures.