• 제목/요약/키워드: Optimized shape

검색결과 839건 처리시간 0.027초

Pharmacopuncture of Bauhinia variegata Nanoemulsion Formulation against Diabetic Peripheral Neuropathic Pain

  • Gupta, Pushpraj S;Singh, Sunil K;Tripathi, Abhishek K
    • 대한약침학회지
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    • 제23권1호
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    • pp.30-36
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    • 2020
  • Objectives: The objective of the study was to prepare Bauhinia variegata loaded nanoemulsion(formulation and determine the efficacy of herbal drug formulation against diabetic peripheral neuropathic pain through acupuncture technique. Methods: Nine different ba tches of nanoemulsion (NE1 NE9) of BVN was prepared by varying the Smix ratio and the concentration of oil. BVN was characterized to determine particle size, shape, zeta potential, polydispersity index, optical transmittance, drug release profile and stora ge stability. The optimized formulation was subjected to plantar test, behavioral tests of neuropathic pain and Von Frey filament stimulation test. Diabetes was induced by intraperitoneal injection of freshly prepared solution of Streptozotocin (60 mg/kg) to the experimental rats. Animals were made diabetic divided into four groups, Group I was untreated normal control group, Group II was diabetic control group, Group III was Bauhinia variegata extract ( treated group (100 mg/kg/day, p.o) and Group IV was BVN treated groups (100 mg/kg/day, p.o) acute and chronically. Results: The prepared B. variegata loaded nanoemulsion was nanosized (124 nm), spherical, uniform and stable over the period of 180 days with no change in physiochemical properties. The bl ood glucose and body weight of animals was normalizing after four weeks of treatment that was significant with BVN in comparison to diabetic control group. The chronic administration of BVN significantly (P<0.001) decreased hind paw withdrawal latency an d attenuated mechanical allodynia as compared with diabetic rats. Conclusion: Thus, BVN may be an effective drug formulation against diabetic peripheral neuropathic pain.

EMP 방호시설의 덕트 및 배관 최적 설계 방안 (Design Optimization for Air Ducts and Fluid Pipes at Electromagnetic Pulse(EMP) Shield in Highly Secured Facilities)

  • 방승기;김재훈
    • 한국지열·수열에너지학회논문집
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    • 제10권4호
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    • pp.15-24
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    • 2014
  • This study conducted a computational fluid dynamics(CFD) analysis to find an appropriate diameter or sectional area of air ducts and fluid pipes which have an electromagnetic pulse(EMP) shied to protect indoor electronic devices in special buildings like military fortifications. The result shows that the optimized outdoor air intake size can be defined with either the ratio of the maximum air velocity in the supply duct to the air intake size, or the shape ratio of indoor supply diffuser to the outdoor air intake. In the case of water channel, the fluid velocity at EMP shield with the identical size of the pipe, decreases by 25% in average due to the resistance of the shield. The enlargement of diameter at the shield, 2 step, improves the fluid flow. It illustrated that the diameter of downstream pipe size is 1step larger than the upstream for providing the design flow rate. The shield increases friction and resistance, in the case of oil pipe, so the average flow velocity at the middle of the shield increase by 50% in average. In consideration of the fluid viscosity, the oil pipe should be enlarged 4 or 5 step from the typical design configuration. Therefore, the fluid channel size for air, water, and oil, should be reconsidered by the engineering approach when EMP shield is placed in the middle of channel.

영구자석 전동기의 코어 형상에 따른 코깅 토크 저감에 관한 연구 (A Study on Reducing Cogging Torque by Core Shapes in Permanent Magnet Motors)

  • 박일환;김동석;박관수
    • 한국자기학회지
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    • 제20권2호
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    • pp.61-67
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    • 2010
  • 근래 첨단 전동기 개발에 고성능 영구자석이 적용됨에 따라 소형 전동기의 고출력화가 가능해진 반면 전동기의 진동과 소음이 커져 그 원인이 되는 코깅 토크에 대한 연구가 필요하게 되었다. 영구자석 전동기의 코깅토크는 영구자석에 의한 자계의 분포에 기인하게 되는데, 전동기의 자계 분포는 코어의 형상에 기인하므로 코어의 형상을 적절하게 설계함으로써 코깅토크를 저감시킬수 있다. 본 논문에서는 영구자석 전동기의 코깅토크를 저감하기 위한 기존의 sub-slot 법을 개선하여 보다 단순화 한 형상으로 코어의 설계변수를 대폭 줄임으로 효과적으로 코깅토크를 저감할 수 있는 기법을 제안하고 이를 영구자석 전동기에 적용하여 기존의 대표적인 sub-slot 법과 비교하고 그 성능을 검증하였다.

ANALYSIS OF THE OPTIMIZED H TYPE GRID SPRING BY A CHARACTERIZATION TEST AND THE FINITE ELEMENT METHOD UNDER THE IN-GRID BOUNDARY CONDITION

  • Yoon Kyung-Ho;Lee Kang-Hee;Kang Heung-Seok;Song Kee-Nam
    • Nuclear Engineering and Technology
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    • 제38권4호
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    • pp.375-382
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    • 2006
  • Characterization tests (load vs. displacement curve) are conducted for the springs of Zirconium alloy spacer grids for an advanced LWR fuel assembly. Twofold testing is employed: strap-based and assembly-based tests. The assembly-based test satisfies the in situ boundary conditions of the spring within the grid assembly. The aim of the characterization test via the aforementioned two methods is to establish an appropriate assembly-based test method that fulfills the actual boundary conditions. A characterization test under the spacer grid assembly boundary condition is also conducted to investigate the actual behavior of the spring in the core. The stiffness of the characteristic curve is smaller than that of the strap-wised boundary condition. This phenomenon may cause the strap slit condition. A spacer grid consists of horizontal and vertical straps. The strap slit positions are differentiated from each other. They affords examination of the variation of the external load distribution in the grid spring. Localized legions of high stress and their values are analyzed, as they may be affected by the spring shape. Through a comparison of the results of the test and FE analysis, it is concluded that the present assembly-based analysis model and procedure are reasonably well conducted and can be used for spring characterization in the core. Guidelines for improving the mechanical integrity of the spring are also discussed.

DESIGN OPTIMIZATION OF RADIATION SHIELDING STRUCTURE FOR LEAD SLOWING-DOWN SPECTROMETER SYSTEM

  • KIM, JEONG DONG;AHN, SANGJOON;LEE, YONG DEOK;PARK, CHANG JE
    • Nuclear Engineering and Technology
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    • 제47권3호
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    • pp.380-387
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    • 2015
  • A lead slowing-down spectrometer (LSDS) system is a promising nondestructive assay technique that enables a quantitative measurement of the isotopic contents of major fissile isotopes in spent nuclear fuel and its pyroprocessing counterparts, such as $^{235}U$, $^{239}Pu$, $^{241}Pu$, and, potentially, minor actinides. The LSDS system currently under development at the Korea Atomic Energy Research Institute (Daejeon, Korea) is planned to utilize a high-flux ($>10^{12}n/cm^2{\cdot}s$) neutron source comprised of a high-energy (30 MeV)/high-current (~2 A) electron beam and a heavy metal target, which results in a very intense and complex radiation field for the facility, thus demanding structural shielding to guarantee the safety. Optimization of the structural shielding design was conducted using MCNPX for neutron dose rate evaluation of several representative hypothetical designs. In order to satisfy the construction cost and neutron attenuation capability of the facility, while simultaneously achieving the aimed dose rate limit (< $0.06{\mu}Sv/h$), a few shielding materials [high-density polyethylene (HDPE)eBorax, $B_4C$, and $Li_2CO_3$] were considered for the main neutron absorber layer, which is encapsulated within the double-sided concrete wall. The MCNP simulation indicated that HDPE-Borax is the most efficient among the aforementioned candidate materials, and the combined thickness of the shielding layers should exceed 100 cm to satisfy the dose limit on the outside surface of the shielding wall of the facility when limiting the thickness of the HDPE-Borax intermediate layer to below 5 cm. However, the shielding wall must include the instrumentation and installation holes for the LSDS system. The radiation leakage through the holes was substantially mitigated by adopting a zigzag-shape with concrete covers on both sides. The suggested optimized design of the shielding structure satisfies the dose rate limit and can be used for the construction of a facility in the near future.

실리콘 박막 태양전지 전면 전극용 ZnO : Al 투명전도막의 표면형상 및 산란광 특성 (Characterization of Surface Morphology and Light Scattering of Transparent Conducting ZnO:Al Films as Front Electrode for Silicon Thin Film Solar Cells)

  • 김영진;조준식;이정철;왕진석;송진수;윤경훈
    • 한국재료학회지
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    • 제19권5호
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    • pp.245-252
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    • 2009
  • Changes in the surface morphology and light scattering of textured Al doped ZnO thin films on glass substrates prepared by rf magnetron sputtering were investigated. As-deposited ZnO:Al films show a high transmittance of above 80% in the visible range and a low electrical resistivity of $4.5{\times}10^{-4}{\Omega}{\cdot}cm$. The surface morphology of textured ZnO:Al films are closely dependent on the deposition parameters of heater temperature, working pressure, and etching time in the etching process. The optimized surface morphology with a crater shape is obtained at a heater temperature of $350^{\circ}C$, working pressure of 0.5 mtorr, and etching time of 45 seconds. The optical properties of light transmittance, haze, and angular distribution function (ADF) are significantly affected by the resulting surface morphologies of textured films. The film surfaces, having uniformly size-distributed craters, represent good light scattering properties of high haze and ADF values. Compared with commercial Asahi U ($SnO_2$:F) substrates, the suitability of textured ZnO:Al films as front electrode material for amorphous silicon thin film solar cells is also estimated with respect to electrical and optical properties.

Design and Manufacture of an Off-axis Aluminum Mirror for Visible-light Imaging

  • Zhang, Jizhen;Zhang, Xin;Tan, Shuanglong;Xie, Xiaolin
    • Current Optics and Photonics
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    • 제1권4호
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    • pp.364-371
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    • 2017
  • Compared to one made of glass, an aluminum mirror features light weight, compact design, low cost, and quick manufacturing. Reflective mirrors and supporting structures can be made from the same material, to improve the athermal performance of the system. With the rapid development of ultraprecise machining technologies, the field of applications for aluminum mirrors has been developed rapidly. However, most of them are rotationally symmetric in shape, and are used for infrared applications. In this paper, the design and manufacture of an off-axis aluminum mirror used for a three-mirror-anastigmat (TMA) optical system at visible wavelengths is presented. An optimized, lightweight design provides a weight reduction of more than 40%, while the surface deformation caused by earth's gravity can meet the required tolerance. The two pieces of an off-axis mirror can be diamond-turned simultaneously in one setup. The centrifugal deformation of the off-axis mirror during single-point diamond turning (SPDT) is simulated through the finite-element method (FEM). The techniques used to overcome centrifugal deformation are thoroughly described in this paper, and the surface error is reduced to about 1% of the original value. After post-polishing, the form error is $1/30{\lambda}$ RMS and the surface roughness is better than 5 nm Ra, which can meet the requirements for visible-light imaging.

해상 상태를 고려한 모바일하버용 크레인의 구조최적설계 (Structural Optimization of the Mobile Harbor Carne Considering Sea State)

  • 이재준;임원종;정성범;정의진;박경진
    • 한국전산구조공학회논문집
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    • 제25권1호
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    • pp.27-36
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    • 2012
  • 모바일하버는 선박의 대형화로 인하여 항만에 접안 및 정박이 불가능하거나 선박의 접안 대기시간이 길어지는 경우 등 항만의 문제점들을 해결하기 위해 제시된 새로운 개념의 시스템이다. 이 새로운 시스템은 해상에 있는 선박에 다가간 후, 모바일하버에 설치된 크레인을 이용하여 선박에 컨테이너를 직접 상, 하역작업을 하도록 고안되었다. 모바일하버용 크레인은 컨테이너를 이송하는 장치로써 그 중요성이 매우 크다. 본 연구에서는 모바일하버용 크레인의 형태들을 제시하고 각 형태에 따른 구조최적설계를 실시하였다. 불안정한 해상으로부터 발생되는 횡동요 및 종동요와 바람에 의한 풍하중을 최적설계의 하중조건으로 하였다. 또 한국선급 및 각각의 규정들을 최적설계의 제한조건으로 하여 규정을 만족하면서 경량화된 크레인 구조를 최적화하였다.

Pulse-reverse도금을 이용한 다층 PCB 빌드업 기판용 범프 생성특성 (Characteristics of Plated Bump on Multi-layer Build up PCB by Pulse-reverse Electroplating)

  • 서민혜;공만식;홍현선;선지완;공기오;강계명
    • 한국재료학회지
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    • 제19권3호
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    • pp.151-155
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    • 2009
  • Micro-scale copper bumps for build-up PCB were electroplated using a pulse-reverse method. The effects of the current density, pulse-reverse ratio and brightener concentration of the electroplating process were investigated and optimized for suitable performance. The electroplated micro-bumps were characterized using various analytical tools, including an optical microscope, a scanning electron microscope and an atomic force microscope. Surface analysis results showed that the electroplating uniformity was viable in a current density range of 1.4-3.0 A/$dm^2$ at a pulse-reverse ratio of 1. To investigate the brightener concentration on the electroplating properties, the current density value was fixed at 3.0 A/$dm^2$ as a dense microstructure was achieved at this current density. The brightener concentration was varied from 0.05 to 0.3 ml/L to study the effect of the concentration. The optimum concentration for micro-bump electroplating was found to be 0.05 ml/L based on the examination of the electroplating properties of the bump shape, roughness and grain size.

탄뎀 가스메탈아크 용접공정의 최적화에 관한 실험적 연구 (An Experimental Study on Optimizing for Tandem Gas Metal Arc Welding Process)

  • 이종표;김일수;이지혜;박민호;김영수;박철균
    • Journal of Welding and Joining
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    • 제32권2호
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    • pp.22-28
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    • 2014
  • To enhance productivity and provide high quality production material in a GMA welding process, weld quality, productivity and cost reduction affects the number of process variables. In addition, a reliable welding process and conditions must be implemented to reduce weld structure failure. In various industries the welding process mathematical model is not fully formulated for the process parameter and on the welding conditions, therefore only partial variables can be predicted. The research investigates the interaction between the welding parameters (welding speed, distance between electrodes, and flow rate of shielding gas) and bead geometry for predicting the weld bead geometry (bead width, bead height). Taguchi techniques are applied to bead shape to develope curve equation for predicting the optimized process parameters and quality characteristics by analyzing the S/N ratio. The experimental results and measured error is within the range of 10% presenting satisfactory accuracy. The curve equation was developed in such a way that you can predict the bead geometry of constructed machinery that can be used for making tandem welding process.