• 제목/요약/키워드: Optimal replacement

검색결과 388건 처리시간 0.048초

상행대동맥 벽내 혈종에 의해 발생한 심낭 압전의 지연 진단 - 1예 보고 - (Delayed Diagnosis of Cardiac Tamponade That Was Caused by Intramural Hematoma of the Ascending Aorta -A case report-)

  • 황유화;송석원;이기종
    • Journal of Chest Surgery
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    • 제43권2호
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    • pp.194-198
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    • 2010
  • 대동맥 벽내 혈종은 대동맥 내벽의 열상 등 손상이 없으면서 대동맥의 혈관벽내의 출혈로 정의되며 고전적인 대동맥 박리로 진행할 수 있는 질환으로 대동맥 박리의 변형된 형태로 여겨지기도 한다. 대동맥 벽내 혈종은 높은 이환율과 사망률을 보이나 궁극적 치료는 아직 확실하지 않다. 하지만 상행 대동맥에 발생한 대동맥 벽내 혈종은 대동맥 파열과 심낭 압전의 위험성으로 인해 보통 수술적인 치료가 고려되고 있다. 저자들은 실신을 주소로 내원한 71세 남환에서 대동맥 벽내 혈종 1예를 수술 치험 하였다. 잘못된 진단으로 인해 응급실 내원 5시간 뒤 시행된 대동맥 단층 컴퓨터 촬영 검사 결과 상행대동맥 벽내 혈종과 심낭 압전 소견이 동반되어 있었으며 이로 인해 급성 신부전, 허혈성 장기손상의 합병증이 발생하였다. 응급 수술로 상행대동맥 및 대동맥궁 치환술을 진행하였고 환자는 수술 14일 뒤 합병증 없이 퇴원하였다.

자일리톨 첨가 머핀의 품질특성 (Quality Characteristics of Muffins with Xylitol)

  • 안혜령;허수진;이광석
    • 한국조리학회지
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    • 제16권3호
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    • pp.307-316
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    • 2010
  • 본 논문의 목적은 자일리톨을 설탕 대체제로 사용하여 만든 머핀의 최적 배합을 개발하고자 함이다. 자일리톨을 첨가한 머핀의 특성은 높이, 부피, 무게, 비용적, 굽기 손실률, 영상분석, 색도와 관능검사에 의해 측정되었고, 저장기간 동안(0, 1, 3, 5일)의 머핀의 노화에 대한 자일리톨의 영향은 조직감 분석 기계에 의해 측정되었다. 자일리톨 첨가량이 증가할수록 머핀의 경도는 증가하였고, 저장기간 동안 유의적으로 증가하였다. 머핀 껍질의 명도(L값)는 자일리톨 첨가에 의해 유의적으로 증가하였다. 관능검사에서 자일리톨을 첨가하지 않은 대조구는 외관과 조직감에 가장 높은 수치를 보였다. 풍미, 맛과 전체적인 기호도에서는 자일리톨을 25% 첨가한 머핀이 가장 좋은 결과를 보였지만 대조구와는 유의적인 차이는 없었다.

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저수온기 치어기 넙치(Paralichthys olivaceus) 사료 내 비타민 C 대체제로서 감귤착즙박의 이용 가능성 및 항생제 대체 효과 (Effect of Dietary Supplementation with Citrus By-product as a Vitamin C Replacement for Juvenile Olive Flounder Paralichthys olivaceus at Low Water Temperatures)

  • 김유정;이초롱;신재형;이경준
    • 한국수산과학회지
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    • 제50권1호
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    • pp.15-24
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    • 2017
  • This study examined the effects of dietary supplementation with citrus by-product (CBP) on the growth, feed utilization, innate immunity, and histology of the gills and intestine of juvenile olive flounder Paralichthys olivaceus during low water temperature season. A vitamin C-free basal diet was regarded as a control and five other diets were formulated that contained 30 and 300 mg of L-ascorbyl-2-polyphosphate (LAPP) or CBP as vitamin C equivalents/kg diet, or the antibiotic oxytetracycline (OTC) (designated as control, LAPP30, LAPP300, CBP30, CBP300, and OTC, respectively). Olive flounder (initial body weight $44.6{\pm}0.32g$) were fed the six experimental diets to apparent satiation for 9 weeks. Growth and feed utilization were significantly higher in CBP30 than in the control and LAPP groups. The lysozyme activity was significantly higher in CBP30 than in LAPP300. Enterocyte height was significantly higher in CBP30 than in the control. The number of goblet cells was increased significantly with LAPP30, LAPP300, and CBP30. These results demonstrate that CBP can reduce or replace vitamin C and antibiotic in the diet of olive flounder during the low-water-temperature season. The optimal CBP supplementation level seems to be approximately 1%, which is equivalent to 30 ppm vitamin C/kg in the fish diet.

Cerebral Arteriovenous Malformation Associated with Moyamoya Disease

  • Noh, Jung-Hoon;Yeon, Je Young;Park, Jae-Han;Shin, Hyung Jin
    • Journal of Korean Neurosurgical Society
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    • 제56권4호
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    • pp.356-360
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    • 2014
  • The coexistence of moyamoya disease (MMD) with an arteriovenous malformation (AVM) is exceedingly rare. We report two cases of AVM associated with MMD. The first case was an incidental AVM diagnosed simultaneously with MMD. This AVM was managed expectantly after encephalo-duro-arterio-synangiosis (EDAS) as the main feeders stemmed from the internal carotid artery, which we believed would be obliterated with the progression of MMD. However, the AVM persisted with replacement of the internal carotid artery feeders by new external carotid artery feeders from the EDAS site. The AVM was eventually treated with gamma knife radiosurgery considering an increasing steal effect. The second case was a de novo AVM case. The patient was initially diagnosed with MMD, and acquired an AVM eight years later that was slowly fed by the reconstituted anterior cerebral artery. Because the patient remained asymptomatic, the AVM is currently being closely followed for more than 2 years without further surgical intervention. Possible differences in the pathogenesis and the radiologic presentation of these AVMs are discussed with a literature review. No solid consensus exists on the optimal treatment of MMD-associated AVMs. Gamma knife radiosurgery appears to be an effective treatment option for an incidental AVM. However, a de novo AVM may be managed expectantly considering the possible risks of damaging established collaterals, low flow characteristics, and probably low risks of rupture.

Optimization of Physical Conditions for Caviar Analog Preparation Using Calcium-alginate Gel Capsules

  • Ji, Cheong-Il;Cho, Sueng-Mock;Yun, Young-Soo;Kim, Seon-Bong
    • Fisheries and Aquatic Sciences
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    • 제10권3호
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    • pp.103-112
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    • 2007
  • High prices, overfishing, and contamination have limited the availability of natural caviar as a food product. We attempted to apply encapsulation by calcium-alginate gel membranes to caviar analog preparation in an effort to produce a high-quality replacement for natural caviar. Physical conditions of stirring speed $(X_1,\;rpm)$ and gelation time $(X_2,\;min)$ as the independent variables for gelation were optimized by response surface methodology. Sphericity $(Y_1,\;%)$, diameter $(Y_2,\;mm)$, membrane thickness $(Y_3,\;mm)$, rupture strength $(Y_4,\;g)$, and rupturing deformation $(Y_5,\;mm)$ were used as the dependent variables to compare characteristics of the capsules for caviar analogs with natural caviar. The values of the independent variables as evaluated by multiple response optimization were $X_1=-0.1271 (278 rpm) and $X_2=0.4436$ (12.2 min), respectively. Predicted values of the four dependent variables were $Y_1=97.7%,\;Y_2=2.97mm,\;Y_4=1,465g,\;and\;Y_5=1.15mm$. Membrane thickness $(Y_3)$ was eliminated from the dependent variables for multiple response optimization because it could not be measured with an image analyzer. The experimental values prepared under the optimal conditions for verification nearly coincided with the predicted values and satisfied the conditions of natural caviar.

Development of a Practical and Cost-Effective Medium for Bioethanol Production from the Seaweed Hydrolysate in Surface-Aerated Fermentor by Repeated-Batch Operation

  • Lee, Sang-Eun;Lee, Ji-Eun;Shin, Ga-Young;Choi, Woon-Yong;Kang, Do-Hyung;Lee, Hyeon-Yong;Jung, Kyung-Hwan
    • Journal of Microbiology and Biotechnology
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    • 제22권1호
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    • pp.107-113
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    • 2012
  • To develop a practical and cost-effective medium for bioethanol production from the hydrolysate of seaweed Sargassum sagamianum, we investigated the feasibility and performance of bioethanol production in CSL (corn-steep liquor)-containing medium, where yeast Pichia stipitis was used and the repeated batch was carried out in a surface-aerated fermentor. The optimal medium replacement time during the repeated operation was determined to be 36 h, and the surface aeration rates were 30 and 100 ml/min. Under these conditions, the repeated-batch operation was successfully carried out for 6 runs (216 h), in which the maximum bioethanol concentrations reached about 11-12 g/l at each batch operation. These results demonstrated that bioethanol production could be carried out repeatedly and steadily for 216 h. In these experiments, the total cumulative bioethanol production was 57.9 g and 58.0 g when the surface aeration rates were 30 ml/min and 100 ml/min, respectively. In addition, the bioethanol yields were 0.43 (about 84% of theoretical value) and 0.44 (about 86% of theoretical value) when the surface aeration rates were 30 ml/min and 100 ml/min, respectively. CSL was successfully used as a medium ingredient for the bioethanol production from the hydrolysate of seaweed Sargassum sagamianum, indicating that this medium may be practical and cost-effective for bioethanol production.

미생물 성장을 억제하기 위하여 수용성 절삭유에 과다하게 첨가한 붕소와 아민 사례 연구 (Ethanolamine and boron abuse to limit microbial growth in water-synthetic metalworking fluids)

  • 박동욱;백도현
    • 한국산업보건학회지
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    • 제15권3호
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    • pp.270-276
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    • 2005
  • This study was conducted to examine whether a specific synthetic metalworking fluid (MWF), "A", in use for 10 months without replacement, displayed microbial resistance and to identify the additives associated with the control of microbial growth. Three synthetic MWF products ("A", "B", and "C") were studied every week for two months. Microbial deterioration of the fluids was assessed through evaluation by endotoxin, bacteria and fungi levels in the MWFs. In addition, formaldehyde, boron, ethanolamine, and copper levels were also studied to determine whether they influence microbial growth in water-based MWFs. Throughout the entire study in the sump where MWF "A" was used, bacteria counts were lower than 103 CFU/mL, and endotoxins never exceeded 103 EU/mL. These levels were significantly lower than levels observed in sumps badly deteriorated with microbes. Boron levels in MWF "A" ranged from 91.7 to 129.6 ppm, which was significantly higher than boron levels found in other MWF products. The total level of ethanolamine (EA) in MWF "A" ranged from 35,595 to 57,857 ppm (average 40,903 ppm), which was over ten times higher than that found in other MWFs. Monoethanolamine (MEA), diethanolamine (DEA) and triethanolamine (TEA) concentrations in MWF "A" were also significantly higher than seen in other MWFs. However, although EA and boron might improve anti-microbial performance, their abuse can pose a serious risk to workers who handle MWFs. From an industrial hygiene perspective, our study results stress that the positive synergistic effect of boron and EA in reducing microbial activity in MWF must be balanced with the potentially negative health effects of such additives. Our study also addresses the disadvantage of failing to comprehensively report MWF additives on Material Safety Data Sheets (MSDS). Future research in MWF formulation is needed to find the best level of EA and boron for achieving optimal synergistic anti-microbial effects while minimizing employee health hazards.

Egg Shell and Oyster Shell Powder as Alternatives for Synthetic Phosphate: Effects on the Quality of Cooked Ground Pork Products

  • Cho, Min Guk;Bae, Su Min;Jeong, Jong Youn
    • 한국축산식품학회지
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    • 제37권4호
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    • pp.571-578
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    • 2017
  • This study aimed to determine the optimal ratio of natural calcium powders (oyster shell and egg shell calcium) as synthetic phosphate replacers in pork products. Ground pork samples were subjected to six treatments, as follows: control (-) (no phosphate added), control (+) (0.3% phosphate blend added), treatment 1 (0.5% oyster shell calcium powder added), treatment 2 (0.3% oyster shell calcium powder and 0.2% egg shell calcium powder added), treatment 3 (0.2% oyster shell calcium powder and 0.3% egg shell calcium powder added), and treatment 4 (0.5% egg shell calcium powder added). The addition of natural calcium powders resulted in an increase in the pH values of meat products, regardless of whether they were used individually or mixed. The highest cooking loss was observed (p<0.05) in the negative control samples, whereas the cooking loss in samples with natural calcium powder added was similar (p>0.05) to that in the positive control samples. CIE $L^*$ values decreased as the amount of added egg shell calcium powder increased. CIE $a^*$ values were higher (p<0.05) in samples containing natural calcium powder (treatments 1, 2, 3, and 4) than in the positive control. The combination of oyster shell calcium powder and egg shell powder (treatment 2 or 3) was effective for the improvement of textural properties of the pork products. The findings show that the combined use of 0.2% oyster shell calcium and 0.3% egg shell calcium should enable the replacement of synthetic phosphate in the production of cooked pork products with desirable qualities.

트레할로스를 첨가한 머핀의 물리적 특성 및 관능평가 (Physical Properties and Sensory Evaluation of Muffins with Trehalose)

  • 허수진;안혜령;이광석
    • 한국조리학회지
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    • 제16권1호
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    • pp.13-23
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    • 2010
  • 이 논문의 목적은 트레할로스를 설탕 대체제로 사용하여 만든 머핀의 최적 배합을 개발하는 것이다. 저장기간 동안(0, 1, 3, 5일) 머핀의 특성과 노화에 대한 트레할로스의 영향은 높이, 부피, 무게, 비용적, 굽기 손실률, 영상분석, 색도, 조직감 측정 그리고 관능 평가에 의해 측정되었다. 트레할로스를 첨가한 머핀의 껍질 두께는 트레할로스 첨가량이 증가할수록 얇아지는 결과를 보였다. 저장 기간동안 머핀의 명도(L값)는 증가하였으나, 트레할로스를 첨가하지 않은 머핀은 감소하였다. 황색도(b값)는 트레할로스 첨가량이 증가할수록 유의적으로 증가하였다. 머핀의 경도는 트레할로스 첨가에 의해서 감소하였으나, 탄성은 트레할로스 첨가에 의해 유의적으로 증가하였다. 마지막으로 관능평가는 질감, 맛, 전체적인 기호도에서 트레할로스 25% 첨가 머핀이 가장 좋은 점수를 보이는 것으로 나타났다.

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유전자 알고리즘을 활용한 데이터 불균형 해소 기법의 조합적 활용 (Combined Application of Data Imbalance Reduction Techniques Using Genetic Algorithm)

  • 장영식;김종우;허준
    • 지능정보연구
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    • 제14권3호
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    • pp.133-154
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    • 2008
  • 데이터 마이닝 분류 문제에서 발생하는 데이터 불균형 문제는 한 범주에 속한 데이터의 수가 다른 범주에 속한 데이터의 수보다 극히 많거나 작은 경우를 말한다. 이러한 불균형 문제를 해결하기 위해 표본추출과 오분류 비용에 근거한 여러 가지 기법들이 제시되었으며, 이들 간의 성능 비교에 대한 연구들도 이루어졌다. 본 논문에서는 기존에 제시된 불균형 문제 해소기법들의 조합적 활용에 대한 타당성에 대해 살펴보고 유전자 알고리즘을 통해 그 결합 비율을 결정하여 더 좋은 성과를 낼 수 있는지에 대해 살펴보도록 한다. 소수 범주에 대한 정확성을 높이기 위해 소수 범주에 대한 F-value에 기초하여 기법들의 결합비율을 결정하고 기존 단일 기법들의 성과와 임의의 비율에 의한 격자표 형태의 결합 성과를 비교하여 결합적 활용의 타당성을 살펴본다. 이를 실증적으로 검토하기 위해서, 일반적으로 데이터 불균형 문제를 해결하기 위해 많이 사용되는 4개의 공개 데이터 집합을 이용하여 타당성 분석을 수행하였다. 분석 결과, 전체적으로 단일 기법들의 결합적 활용이 데이터 불균형 해소에 유용한 것으로 나타났다.

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