• 한국동물생명공학회지
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• 제34권3호
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• pp.190-196
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• 2019

Tight junctions are constituents of the blood-epididymis barrier that play roles in regulating the unidirectional transcellular transport of ions, water, and solutes to maintain optimal conditions for sperm maturation and storage. Claudin 1 (Cldn1) and 4 (Cldn4) are known as tight junction proteins and are expressed in the basolateral membranes as well as tight junctions in the epididymis of rodents. Here, we examined the expression and localization of Cldn1 and 4 to determine the function of these proteins in the pig epididymis. Cldn1 was highly expressed in the basolateral membrane of epithelial cells in the caput and corpus regions of the epididymis. In the cauda region, however, Cldn1 labeling was significantly decreased in the basolateral membrane of epithelial cells. In contrast, labeling indicated that Cldn4 was expressed in the basolateral membrane in the cauda region of the epididymis and was present at punctate reactive sites in the caput and corpus regions. However, in no region of the epididymis did we detect colocalization of Cldn1 and 4 with labeled ZO-1, the distribution of which is restricted to the tight junctions. Our results indicate that Cldn1 and 4 were region-specifically expressed in the pig epididymis but not present in the tight junctions of epididymal epithelium. In addition, reciprocal regulation in specific regions of the epididymis between Cldn1 and 4 may play an important role in generating an optimal luminal environment for sperm maturation and storage in the pig epididymis.

• 대한두개안면성형외과학회지
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• 제23권3호
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• pp.103-110
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• 2022

Background: The primary objectives of mandibular surgery are to achieve optimal occlusion, low sensory disturbance, and adequate fixation with early movement. In-depth knowledge of the mandibular structure is required to achieve these goals. This study used computed tomography (CT) to evaluate the mandibular cortical thickness and cancellous space according to age and sex. Methods: We enrolled 230 consecutive patients, aged 20 to 50 years, who underwent CT scanning. The cortex and cancellous space centered around the inferior alveolar nerve (IAN) canal were measured at two specific locations: the lingula and second molar region. Statistical analysis of differences according to increasing age and sex was performed. Results: The t-test revealed that the cancellous space and cortical thickness differed significantly with respect to the threshold of 35 years of age. Both cortical thickness and cancellous space in the molar region were negatively correlated with age. Meanwhile, both cortical thickness and cancellous space in the lingula region showed a positive correlation with age. With respect to sex, significant differences in the cancellous space at the molar region and the cortical thickness at the lingula were observed. However, no further statistically significant differences were observed in other variables with respect to sex. The sum of each measurement on the mandibular body reflected the safe distance from the surface of the outer cortex to the IAN canal. The safe distances also showed statistically significant differences between those above and below 35 years of age. Conclusion: Knowledge of the anatomical structure of the mandible and of changes in bone structure is crucial to ensure optimal surgical outcomes and avoid damage to the IAN. CT examination is useful to identify changes in the bone structure, and these should be taken into account in the planning of surgery for older patients.

• 제어로봇시스템학회논문지
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• 제17권2호
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• pp.79-87
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• 2011

This paper presents the optimal design of an overlapped ultrasonic sensor ring for high resolution obstacle detection of an autonomous mobile robot. It is assumed that a set of low directivity ultrasonic sensors of the same type are arranged along a circle of nonzero radius at a regular spacing with their beams overlapped. First, taking into account the dead angle region, the entire range of obstacle detection is determined with reference to the center of an overlapped ultrasonic sensor ring. Second, the optimal design index of an overlapped ultrasonic sensor ring is defined as the area closeness of three sensing subzones resulting from beam overlap. Third, the lower and upper bounds on the number of ultrasonic sensors are derived, which can guarantee minimal beam overlap and also avoid excessive beam overlap among adjacent ultrasonic sensors. Fourth, employing a commercial low directivity ultrasonic sensor, an optimal design example of an overlapped ultrasonic sensor ring is given along with the ultrasonic sensor ring prototype mounted on top of a mobile robot. Finally, some experimental results using our prototype ultrasonic sensor ring are given to demonstrate the validity and performance of an optimally overlapped ultrasonic sensor ring for high resolution obstacle detection.

• 한국지구물리탐사학회:학술대회논문집
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• 한국지구물리탐사학회 2003년도 Proceedings of the international symposium on the fusion technology
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• pp.684-689
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• 2003

One field identified by an inverse method is one of multiple candidate solutions those are independently obtained through a specific estimation technique. While averaging of optimized fields can provide a better description of the spatial feature of an unknown field, it deteriorates the flow and transport characteristics of the optimized fields. As a result, the averaged field is not suited for modeling aquifer performances. Based on genetic algorithm, an optimal field synthesis technique is developed, which combines diversely optimized fields into a refined group of fields. Each field in the population is paired, and a sub-region of each field is exchanged by crossover operation to create a group of synthesized fields of enhanced modeling capability. The population of the fields is evolved till the synthesized fields become sufficiently similar. Applications of the optimal field synthesis to synthetic cases indicate that the objective functions of the fields assessing the modeling capabilities are further reduced after the optimal field synthesis. The identified fields from various inverse techniques may yield a range of modeling results under varied flow situations. The uncertainty is narrowed down through the optimal field synthesis and the associated modeling results converge on that of the reference field. The developed inverse modeling facilitates the construction of a reliable simulation model and hence trustworthy predictions of the future performances.

• 제어로봇시스템학회논문지
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• 제19권6호
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• pp.555-562
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• 2013

This paper presents the optimal array of optical mice for the accurate velocity estimation of a mobile robot. It is assumed that there can be some restriction on the installation of two or more optical mice at the bottom of a mobile robot. First, the velocity kinematics of a mobile robot with an array of optical mice is derived, which maps the velocity of a mobile robot to the velocities of optical mice. Second, taking into account the consistency in physical units, the uncertainty ellipsoid is obtained to represent the error characteristics of the mobile robot velocity estimation owing to noisy optical mouse measurements. Third, a simple but effective performance index is defined as the inverse of the volume of the uncertainty ellipsoid, which can be used for the optimization of the optimal optical mouse placement. Fourth, simulation results for the optimal placement of three optical mice within a given elliptical region are given.

• 대한기계학회논문집B
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• 제26권7호
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• pp.945-950
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• 2002

Shape optimization of a flow system is done to obtain the required effects, in the engineering fields. Most of these designs are accomplished by empirical or numerical analysis. In empirical analysis, it is difficult to obtain an optimal shape in the feasible design region. And, in numerical method, it usually needs much calculation expenses for shape optimization, because of design sensitivity analysis. In this study, we used the growth-strain method having only one distributed parameter such as a design variable. It optimizes a shape by making a distributed parameter such as dissipation energy uniform in a flow system, and then applied to two-flow systems. In order to overcome the stability occurred in numerical analysis performed by Azegami, the equation of volumic strain has been modified. Also, the shapes were compared with the known optimal shapes for the flow systems. Consequently, we confirm that the modified growth-strain method is very efficient and practical in shape optimization of the flow systems.

• 한국전자통신학회논문지
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• 제10권2호
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• pp.267-274
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• 2015

본 논문은 OpenCV 라이브러리를 기반으로 골프공 인식을 위한 신경망의 최적화 구조와 관심영역의 빛의 명도를 계산한다. 개발된 시스템은 전처리, 영상처리, 기계 학습 과정으로 구성되며, 기계 학습과정은 테스트 영상으로부터 골프공과 다른 오브젝트에 대한 Hu의 7 불변 모멘트, 가로 및 세로 비율 또는 면적으로부터 계산된 ${\pi}$를 입력으로 사용하여 다층 퍼셉트론을 기반으로 학습모델을 구한다. 다층 퍼셉트론에 대한 최적의 은닉층과 노드의 수를 결정하도록 모의 실험한 결과 2개의 은닉층과 각 은닉층에 9개의 노드를 가질 때 최대의 인식율과 최소 실행 시간을 얻었다. 그리고 관심영역의 최적 명도는 200으로 계산되었다.

• 한국지능시스템학회논문지
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• 제22권6호
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• pp.687-693
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• 2012

본 논문에서는 군집로봇의 효과적인 협조탐색을 위한 탐색영역에 대한 군집로봇의 최적배치을 제안한다. 먼저, 탐색영역에 대한 최적의 배치를 위해 보로노이 테셀레이션과 K-mean 알고리즘을 이용하여 탐색영역을 분할한다. 분할된 영역을 안전한 주행을 위해 전역경로계획과 지역경로계획을 한다. 전역경로계획은 A*알고리즘을 이용하여 전역경로계획을 하여 최적의 전역경로를 찾고, 지역경로계획은 포텐셜 필드방법을 이용하여 장애물 회피 통해 안전하게 목표점에 이르게 한다. 마지막으로 제안한 알고리즘은 시물레이션을 통해 그 응용가능성을 검토한다.

• 정보처리학회논문지B
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• 제9B권4호
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• pp.501-508
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• 2002

본 논문에서는 영상 내에 존재하는 객체영역의 컬러비와 모멘트를 이용한 영상검색을 제안한다. 객체는 영상의 중심에 위치한다는 가설 하에 미리 정의한 중심영역의 우세컬러를 기반으로 수평-수직 투영을 이용하여 객체영역과 배경영역을 분할함으로써 최적의 공간정보를 획득한다. 또한 영상 내 객체의 회전 및 크기에 불변한 특성을 가지기 위해 컬러비와 모멘트를 특징정보로 이용하며 유사성 측정은 컬러 히스토그램의 구간별 연관성을 고려하기 위해 변형된 히스토그램 인터섹션을 이용한다. 실험결과 제안한 방법이 기존의 영역분할에 의한 방법보다 효율적인 결과를 보였다.

• 대한전기학회논문지:전력기술부문A
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• 제53권4호
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• pp.221-226
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• 2004

Power system has recently used Double-circuit Line and Multi-circuit Line in the industrial development. This has an advantage of system stability and reliability, but the complexity of the system has a disadvantage that makes it difficult to protect the power line. Double-circuit Line has two operation conditions in the Single-circuit operation and Double-circuit operation, so it has mutual impedance. To make it possible for the remaining single-line to operate independently while there is a fault with first line or when maintenance is needed, a trip region for the single-circuit operation should be set in order to set the relay trip region. An optimal trip region for each operation, a different operational conditions for the relay setting should be calculated. In this paper, trip regions of each operation condition have been compared by considering mutual impedance and fault resistance that led to the calculation of fault impedance. Also, as we know that one of the advantages in the distance relay is the back-up protection, we calculated the trip region(Zone-2) in consideration of the mutual impedance.