• Title/Summary/Keyword: Operation & Maintenance

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Bioreactor Operating Strategy in Scultellaria baicalensis G. Plant Cell Culture for the Production of Flavone Glycosides (Flavonoid 배당체 생산을 위한 Scutellaria baicalensis G. 식물 세포 배양에서 생물반응기 운전전략)

  • 최정우;조진만;이정건;이원홍;김익환;박영훈
    • KSBB Journal
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    • v.13 no.3
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    • pp.259-267
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    • 1998
  • Optimal feeding strategies in bioreactor operation of Scutellaria baicalensis G. plant cell culture were investigated to maximize the production of flavone glycosides by using a structured kinetic model which can predict culture growth and flavone glycosides synthesis in a rigorous, quantitative manner. For the production of baicalin and wogonin-7-0-GA, the strategies for glucose feeding into Scutellaria baicalensis G. plant cell culture were proposed based on the model, which are a periodic fed-batch operation with maintenance of cell viability and of specific production rate respectively, and a perfusion operation with maintenance of specific production rate for baicalin and wogonin-7-0-GA. Simulation results showed that the highest volumetric concentration of flavone glycosides was obtained in a periodic fed-batch operation with maintenance of cell viability among all the suggested strategies. In the periodic fed-batch operations, the higher volumetric production of flavone glycosides was achieved compared with that in the perfusion operation. It can be concluded that a periodic fed-batch operation with maintenance of cell viability would be the optimal and practical operating strategy of Scutellaris baicalensis G. plant cell culture for the production of flavone glycosides.

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Analysis of cavity expansion based on general strength criterion and energy theory

  • Chao Li;Meng-meng Lu;Bin Zhu;Chao Liu;Guo-Yao Li;Pin-Qiang Mo
    • Geomechanics and Engineering
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    • v.37 no.1
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    • pp.9-19
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    • 2024
  • This study presents an energy analysis for large-strain cavity expansion problem based on the general strength criterion and energy theory. This study focuses on the energy dissipation problem during the cavity expansion process, dividing the soil mass around the cavity into an elastic region and a plastic region. Assuming compliance with the small deformation theory in the elastic region and the large deformation theory in the plastic region, combined with the general strength criterion of soil mass and energy theory, the energy dissipation solution for cavity expansion problem is derived. Firstly, from an energy perspective, the process of cavity expansion in soil mass is described as an energy conversion process. The energy dissipation mechanism is introduced into the traditional analysis of cavity expansion, and a general analytical solution for cavity expansion related to energy is derived. Subsequently, based on this general analytical solution of cavity expansion, the influence of different strength criterion, large-strain, expansion radius, cavity shape and characteristics of soil mass on the stress distribution, displacement field and energy evolution around the cavity is studied. Finally, the effectiveness and reliability of theoretical solution is verified by comparing the results of typical pressure-expansion curves with existing literature algorithms. The results indicate that different strength criterion have a relatively small impact on the displacement and strain field around the cavity, but a significant impact on the stress distribution and energy evolution around the cavity.

RIMS project application raising for a public transportation immediacy operation (공공교통 전동차 안전운행을 위한 RIMS 프로젝트 적용 제고)

  • Son Young-Jin;Lee Kang-won;Bang yeon-goon;Lee do-sun
    • Proceedings of the KSR Conference
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    • 2005.11a
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    • pp.897-901
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    • 2005
  • 21 century as the knowledge information anger society now our society industry of all fields the rolling stock maintenance conservative standardization enterprise where information anger is being turning out construction Ministry of Transportation supported with continuous development of the supply section substitution quantity information processing system which the information highway is quick and the Korean railroad technical research worker propelled the enterprise as the subjective agency, it contracted this for a vehicle field information anger system construction in link of the enterprise our construction and an agreement, information technique composed the consortium t9day and it propelled a system codevelopment. The SMSC who is a front-runner of Maj loach city railroad operation agency to 'here business relates with a vehicle field maintenance conservativeness an immediacy operation and generally and information anger it will plan it will integrate it will own jointly and business efficiency and in the dictionary an obstacle occurrence electromotive car maintenance conservative information and it will improve only maintenance conservativeness of preventive maintenance of the electromotive car it knows it will prevent to construct the maintenance conservative system of the preventive maintenance, it applied the RIMS project to sleep.

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An Empirical Study on Contract Model for IT Outsourcing Application Operation (IT 아웃소싱 어플리케이션 운영 계약모델에 대한 실증적 연구)

  • Kim, Heungshik;Park, Soah
    • Journal of Information Technology Services
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    • v.16 no.2
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    • pp.45-60
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    • 2017
  • The study suggests a contract model of application operation through case study of A bank's IT outsourcing application contract based on workload. The IT outsourcing order form has a problem in that the scope of work is ambiguous due to the integration of operation and maintenance. In this study, application operation and maintenance were separated by referring to application operation history provided in ISO/IEC15504-5 standard. The scope of the IT outsourcing service was clarified by organizing the definition and detail activities of the application operation business. Application operation contract method has generally applied estimation method by the number of input manpower and period by agreement between buyer and client. As there is no activity to calculate the number of input manpower based on the operational work history and based on the standard workload per activity. In this case is not guaranteed due to the simple agreement between the contractors. In this paper, we propose an application operating cost estimation model that measures the size of the operating software using function point analysis that is the basis of application operation tasks. In order to verify the validity of the application operation cost model, we verified the correlation between the application size and the labor cost through regression analysis using SPSS.

A Study on Airplane Maintenance Engineers and Pilots Relationships and Effectiveness of Flight Operation (항공정비사와 조종사의 관계 및 운항성과에 관한 연구)

  • 강인원;최세종
    • Journal of Korean Society of Transportation
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    • v.21 no.3
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    • pp.23-35
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    • 2003
  • This paper investigates the effectiveness of flight operation between airplane maintenance engineers and pilots who work together. The developed model is to identify the relationship between the attitudes of airplane maintenance engineers and pilots and the effectiveness of flight operation. The results indicate that the shared values and balanced power between airplane maintenance engineers and pilots are positively related with trust and job satisfaction, but conflict is negatively related. Further, trust and job satisfaction positively affect the effectiveness of flight operation. These findings suggest that the improvements of the relationships between airplane maintenance engineers and pilots need more efforts to ensure the aviation safety and efficient flights.

A Study on the Maintenance System Module Design for the BTL Project Facilities : Focused on Educational Facilities (임대형 민자사업(BTL) 발주 시설물의 합리적 유지관리시스템 모듈 설계에 관한 연구 -교육시설물을 중심으로-)

  • Kim, Sang-Seok;Son, Jae-Ho;Lee, Seung-Hyun;Kim, Jae-On
    • Proceedings of the Korean Institute Of Construction Engineering and Management
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    • 2008.11a
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    • pp.702-707
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    • 2008
  • BTL projects for educational facilities were conceived in 2005 to supply public facilities in a timely and efficient manner After the projects were completed in March 2007, proper facility maintenance has become an increasingly important issue. However, BTL projects are still in an early developmental stage, and the data on the maintenance and operation of such facilities are not yet available because the operation of the facilities has just begun. Accordingly, this study is conducted to derive maintenance processes and to specify maintenance items for the efficient maintenance of BTL educational facilities. Then, database on the maintenance processes will be created, and a maintenance system module will be designed.

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A Study on Constructing the RCM-based Failure Analysis System for Railway Facilities & Equipments (RCM 기반 철도시설물 고장분석시스템 구축 - 서울메트로 -)

  • Jung, Kwan-Soo;Seo, Kwang-Hyuk;Lee, Jung-Joo;Nam, Jin-Geun
    • Proceedings of the KSR Conference
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    • 2011.10a
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    • pp.881-895
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    • 2011
  • Seoul Metro railway facilities' inspection and maintenance tasks cause failure analysis, but if there is trouble the diverse cause investigation and the systematic analysis and management among broken facilities, related facilities and components fell short and the conditions are different. And, excess and insufficiency, under inspection and maintenance, is being raised regardless of the introduction year and the operating environment including the number of use by applying the same facilities in the uniform inspection cycle. In this study, we will analysis systematically facility system information, failures, operational status, performance, fault and maintenance information resulting from the maintenance management of railway facilities and derive the relationship between associated equipment and its components. In addition, optimizing the inspection and the maintenance cycles of railway facilities, we will improve the reliability of operation. Considering the probability of risk, it is possible to predict the occurrence of accidents or faults and to minimize the frequency of breakdown by pre-inspection maintenance. Finally, This paper is to introduce the content of constructing the Seoul Metro RCM-based failure analysis system for railway facilities to support the optimal continuance of operation status of equipments and the securement of the safe operation of vehicles.

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Graphic Simulator for Analyzing the Remote Operation of the Advanced Spent Fuel Conditioning Process

  • Song, Tai-Gil;Kim, Sung-Hyun;Lee, Jong-Ryul;Yoon, Ji-Sup
    • 제어로봇시스템학회:학술대회논문집
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    • 2003.10a
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    • pp.1319-1322
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    • 2003
  • KAERI is developing the Advanced Spent Fuel Conditioning Process (ACP) as a pre-disposal treatment process for spent fuel. Equipment used for such a spent fuel recycling and management process must operate in intense radiation fields as well as in a high temperature. Therefore, remote maintenance has a played a significant role in this process because of combined chemical and radiological contamination. Hence suitable remote handling and maintenance technology needs to be developed along with the design of the process concepts. To do this, we developed the graphic simulator for the ACP. The graphic simulator provides the capability of verifying the remote operability of the process without fabrication of the process equipment. In other words, by applying virtual reality to the remote maintenance operation, a remote operation task can be simulated in the graphic simulator, not in a real environment. The graphic simulator will substantially reduce the cost of the development of the remote handling and maintenance procedure as well as the process equipment, while at the same time producing a process and a remote maintenance concept that is more reliable, easier to implement, and easier to understand.

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A Study on the Efficient Operation of Automated Teller Machine(ATM) Maintenance Using Simulation (시뮬레이션을 이용한 금융 ATM기 유지보수의 효율적 운영에 관한 연구)

  • Yu, Hyeung-Keun;Lee, Kang-Won
    • Korean Management Science Review
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    • v.28 no.1
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    • pp.107-116
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    • 2011
  • The automated teller machine (ATM) is developed as a system to provide customers with an easy deposit and withdrawal of their money without time restriction and be served for 24 hours. Today, ATM is come up to the level of an unmanned branch. The automatic financing system is developed as an essential one for dealing with the rationalization of management and the globalization of financing in order to improve the efficiency of financial management work and increase the customer service quality. With reducing the operational cost of financial organizations through the efficient maintenance operation of ATM and increasing the service quality through the maximization of its processing efficiency, this study is to draw the scheme to ensure the competitiveness among the finance companies. The importance of ATM is highly recognized as the utilization of ATM is increased and the processing function is extended, but ATM is quite vulnerable to the malfunction occurred during the nighttime after banking hours. The ATM maintenance is done through consignment to the specialized maintenance company. The efficient operation of ATM maintenance work is important to the satisfaction of customer using ATM in the nighttime.

An estimation method for the maintenance timing of the infiltration trench (침투도랑 시설의 유지관리 시점 산정방법에 관한 연구)

  • Lee, Seung Won;Cha, Sung Min
    • Journal of Korean Society on Water Environment
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    • v.36 no.1
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    • pp.29-35
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    • 2020
  • To manage the non-point source pollution and restore the water circulation, many technologies including infiltration or reservoir systems were installed in the urban area. These facilities have many problems regarding maintenance as their operation period becomes lengthier. The purpose of this study was to estimate the optimal maintenance timing through a long-term load test on the infiltration trench as one of the low impact development techniques. An infiltration trench was installed in the demonstration test facility, and stormwater was manufactured by Manual on installation and operation of non-point pollution management facilities from the Ministry of Environment, Korea and entered into the infiltration trench. Particle size distribution (PSD), suspended solids (SS) removal efficiency, and infiltration rate change tests were performed on inflow and outflow water. In case of the PSD, the maximum particulate size in the outflow decreased from 64 ㎛ to 33 ㎛ as the operating duration elapsed. The SS removal efficiency improved from 97 % to 99 %. The infiltration rate changed from 0.113 L/sec to 0.015 L/sec during the operation duration. The maintenance timing was determined based on the stormwater runoff requirements with these changes in water quality and infiltration rate. The methodologies in this study could be used to estimate the timing of maintenance of other low impact development techniques.