• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제22권4호
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• pp.350-357
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• 2019

Purpose: This study aimed to evaluate a possible association between the anti-tissue transglutaminase antibody (anti-tTG) titer and stage of duodenal mucosal damage and assess a possible cut-off value of anti-tTG at which celiac disease (CD) may be diagnosed in children in conjunction with clinical judgment. Methods: This observational study was conducted at a gastroenterology clinic in a tertiary hospital from April 2012 to May 2013. Seventy children between 6-months and 18-years-old with suspected CD underwent celiac serology and duodenal biopsy. Statistical analyses were done using SPSS 16. Diagnostic test values were determined for comparing the anti-tTG titer with duodenal biopsy. An analysis of variance and Tukey-Kramer tests were performed for comparing the means between groups. A receiver operating characteristics curve was plotted to determine various cut-off values of anti-tTG. Results: The mean antibody titer increased with severity of Marsh staging (p<0.001). An immunoglobulin (Ig) A-tTG value at 115 AU/mL had 76% sensitivity and 100% specificity with a 100% positive predictive value (PPV) and 17% negative predictive value (NPV) for diagnosis of CD (p<0.001, 95% confidence interval [CI], 0.75-1). Conclusion: There is an association between the anti-tTG titer and stage of duodenal mucosal injury in children with CD. An anti-tTG value of 115 AU/mL (6.4 times the upper normal limit) had 76% sensitivity, 100% specificity, with a 100% PPV, and 17% NPV for diagnosing CD (95% CI, 0.75-1). This cut-off may be used in combination with clinical judgment to diagnose CD.

• 한국항행학회논문지
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• 제23권3호
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• pp.245-250
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• 2019

관성항법장치는 시간 경과에 따라 관성센서 및 초기정렬 오차로 인해 항법 오차가 발생한다. 이를 보상하기 위한 방법으로 위성항법시스템 및 속도계 등을 이용하여 보정항법을 수행한다. 수중 환경에서는 GNSS 신호가 통하지 않기 때문에, 수중운동체에 탑재한 관성항법장치는 주로 속도계 보조센서를 이용하여 보정항법을 수행한다. 속도계 보조센서는 DVL, EM-Log, RPM이 있으며, 시스템 환경에 따라서 센서 종류가 적용된다. 본 논문은 고속 및 심해 환경에서 운용되는 관성항법장치의 RPM 속도보정항법을 설계하였다. 또한 직진 방향의 성분을 갖는 RPM 속도계의 한계를 보완하며, 해조류 속도 오차를 보상하는 알고리즘을 제안하였다. 제안한 알고리즘은 몬테카를로 시뮬레이션 결과를 통해 성능을 입증하였다.

• 대한방사선기술학회지:방사선기술과학
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• 제44권4호
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• pp.307-313
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• 2021

The purpose of this study was to analyze the risk factors for uterine myoma diagnosed by ultrasonography in Korea women and to evaluate the risk. Among the patients who visited the outpatient department of obstetrics and gynecology at I hospital in Busin between January 2019 and March 2021 for the purpose of examination, 98 patients in the experimental group diagnosed with uterine myoma and 163 patients in the normal control group without other diseases were retrospectively conducted. Among the general characteristics of the subjects, age, body mass index, parity, and menopause showed significant differences between the myoma group and the normal control group. ROC(receiver operating characteristic) curve analysis and logistic regression analysis were performed to obtain the cut off value and odds ratio that can predict the occurrence of uterine myoma. The cut off value for the prediction of uterine myoma was determined to be 30 years old and a body mass index of 23 kg/m². After that adjusting for menopause, non menopausal cases with a body mass index of 23 kg/m² and over 39 years of age had the highest odds ratio of 6.04. Therefore, premenopausal women over 40 years of age require regular checkups and thorough weight management. This study was conducted with a small number of subjects. Therefore, there is a limit to generalizing to all Korean women. However, based on this study if a large scale prospective study considering various variables is made, it can play a role as a predictive marker in early detection of uterine myoma.

• 한국압력기기공학회 논문집
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• 제16권2호
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• pp.1-9
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• 2020

Large-scale industrial facility structures continue to deteriorate due to the effects of operating and environmental conditions. The problems of these industrial facilities are potentially causing economic losses, environmental pollution, casualties, and national losses. Accordingly, in order to prevent disaster accidents of large structures in advance, the necessity of diagnosing structures using non-destructive inspection techniques is being highlighted. The defect occurrence, location and defect type of the structure are important parameters for predicting the remaining life of the structure, so continuous defect observation is very important. Recently, many researchers have been actively researching real-time monitoring technology to solve these problems. Structure Health Monitoring Inspection is a technology that can identify and respond to the occurrence of defects in real time, but there is a limit to check the degree of defects and the direction of growth of defects. In order to compensate for the shortcomings of these technologies, the importance of defect imaging techniques is emerging, and in order to find defects in large structures, a method of inspecting a wide range using guided ultrasonic is effective. The work presented here introduces a calculation for the shape factor for evaluation of the damaged area, as well as a variable β parameter technique to correct a damaged shape. Also, we perform research in modeling simulation and an experiment for comparison with a suggested inspection method and verify its validity. The curved structure image obtained by the advanced RAPID algorithm showed a good match between the defect area and the shape.

• 셀메드
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• 제11권1호
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• pp.2.1-2.8
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• 2021

The clinical condition Amnesia causes difficulty in learning new information and the inability to recall past events. It is primarily concerned with recent memory loss. Majoon-e-Nisyan (MJN) is a polyherbal Unani formulation, present in a semi-solid form. It is widely used potent drug of the Unani System of Medicine (USM) for treating Nisyan (amnesia). In the present study polyherbal Unani formulation, MJN has been studied for its quality control and acute toxicity. Standardization (quality control) of drugs deals with drug identity, drug quality and purity determination. Standardization of MJN had been done as per the Unani pharmacopoeial parameters approved by World Health Organization (WHO) - Pharmacognostical parameters, Physico-chemical parameters, high-performance thin-layer chromatography (HPTLC), microbial load, aflatoxin, and heavy metals. Solvents and chemicals used in the study were of analytical grade and used instrument were calibrated. By conducting an acute oral toxicity study in rats, the safety of MJN was assessed. The limit test method of OECD guideline 425 was followed in the study. Results of standardization and standard operating procedures (SOPs) for preparation of MJN may serve as the standard reference in the future. The data generated in the study for the quality control of MJN proved the quality of formulation and shows that MJN is not toxic in rats following acute dosing up to 2000 mg/kg bw. The data obtained in the paper for MJN may be used as a standard guideline for preparation of the formulation which can save time, cost, and resources for future research endeavours.

• Journal of Electrochemical Science and Technology
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• 제13권1호
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• pp.78-89
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• 2022

ANODE-free Li-metal batteries (AFLMBs) operating with Li of cathode material have attracted enormous attention due to their exceptional energy density originating from anode-free structure in the confined cell volume. However, uncontrolled dendritic growth of lithium on a copper current collector can limit its practical application as it causes fatal issues for stable cycling such as dead Li formation, unstable solid electrolyte interphase, electrolyte exhaustion, and internal short-circuit. To overcome this limitation, here, we report a novel dual-salt electrolyte comprising of 0.2 M LiPF₆ + 3.8 M lithium bis(fluorosulfonyl)imide in a carbonate/ester co-solvent with 5 wt% fluoroethylene carbonate, 2 wt% vinylene carbonate, and 0.2 wt% LiNO₃ additives. Because the dual-salt electrolyte facilitates uniform/dense Li deposition on the current collector and can form robust/ionic conductive LiF-based SEI layer on the deposited Li, a Li/Li symmetrical cell exhibits improved cycling performance and low polarization for over 200 h operation. Furthermore, the anode-free LiFePO₄/Cu cells in the carbonate electrolyte shows significantly enhanced cycling stability compared to the counterparts consisting of different salt ratios. This study shows an importance of electrolyte design guiding uniform Li deposition and forming stable SEI layer for AFLMBs.

• 한국전자통신학회논문지
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• 제17권5호
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• pp.767-774
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• 2022

본 논문에서는 우리나라에서 운용 중인 4개 제조사 윈드프로파일러의 성능 평가 및 품질관리의 방향성을 제시하기 위해 원시 스펙트럼 자료를 분석하였다. 계절별로 평균한 스펙트럼의 프로파일과 파워 스펙트럼 밀도(PSD, Power Spectrum Density)로 산출한 4가지 통계값(최소, 평균, 중앙, 최댓값)의 프로파일을 활용하였다. 스펙트럼 자료의 품질은 LAP-3000이 가장 우수하였고, YKJ3, PCL-1300, CLC-11-H가 뒤를 이었다. 철원과 추풍령에 설치된 PCL-1300은 지형과 비기상 신호로 인한 스펙트럼의 변동성이 커서 지형 클러터 제거와 이동평균, 멀티피크 등의 신호처리 과정이 요구되었다. 군산과 파주에 설치된 CLC-11-H는 직류 치우침과 전파거리 접힘 현상이 발견되어 직류 치우침 제거와 관측 유효 고도 제한이 선행될 필요가 있다.

• 항공우주시스템공학회지
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• 제15권3호
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• pp.93-98
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• 2021

유럽의 경우 항공기 엔진 개발 시 유럽항공안전청(EASA)에서 제시한 형식증명 기준을 통과해야 한다. 그 중에서 엔진의 운전한계조건에서의 엔진 구조 안정성을 입증하기 위하여 150시간 내구시험을 수행해야 한다. 150시간 내구 시험의 만족기준은 유럽항공안전청의 형식증명 기준인 JAR-E에 명시되어 있다. 현재 국외 엔진 원제작사와 협업을 통하여 Arriel 2L2 엔진을 개발 중에 있으며, 형식 증명을 위하여 150시간 내구 시험을 수행하였다. 본 연구에서는 개발대상 엔진인 Arriel 2L2 엔진의 설계 및 운용 특성을 고려한 150시간 내구시험 수행 및 절차를 정립하였다.

• 드라이브 ㆍ 컨트롤
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• 제20권3호
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• pp.15-24
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• 2023

The aim of this study was to measure and evaluate the exhaust emission factors of agricultural tractors. Engine characteristics and three exhaust emissions (CO, NO_x, PM) were collected under actual agricultural operating conditions. Experiments were performed on idling, driving, plow tillage, and rotary tillage. The load factor (LF) was calculated using the collected engine data, and the emission factor was analyzed using the LF and exhaust emissions. The engine characteristics and exhaust emissions were significantly different for each working condition, and in particular, the LF was significantly different from the currently applied 0.48 LF. The data distribution of exhaust emissions was different depending on the engine speed. In some conditions, the emission factor was higher than the exhaust emission standards. However, since most emission limit standards are values calculated using an engine dynamometer, even if the emission factor measured under actual working conditions is higher, it cannot be regarded as wrong. It is expected that the results of this study can be used for the inventory construction of a calculation for domestic agricultural machinery emissions in the future.

• 대기
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• 제33권4호
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• pp.423-440
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• 2023

The updated version of Global Ocean Data Assimilation and Prediction System (GODAPS) in the NIMS/KMA (National Institute of Meteorological Sciences/Korea Meteorological Administration), which has been in operation since December 2021, is being introduced. This technical note on GODAPS2 describes main progress and updates to the previous version of GODAPS, a software tool for the operating system, and its improvements. GODAPS2 is based on Forecasting Ocean Assimilation Model (FOAM) vn14.1, instead of previous version, FOAM vn13. The southern limit of the model domain has been extended from 77°S to 85°S, allowing the modelling of the circulation under ice shelves in Antarctica. The adoption of non-linear free surface and variable volume layers, the update of vertical mixing parameterization, and the adjustment of isopycnal diffusion coefficient for the ocean model decrease the model biases. For the sea-ice model, four vertical ice layers and an additional snow layer on top of the ice layers are being used instead of previous single ice and snow layers. The changes for data assimilation include the updated treatment for background error covariance, a newly added bias scheme combined with observation bias, the application of a new bias correction for sea level anomaly, an extension of the assimilation window from 1 day to 2 days, and separate assimilations for ocean and sea-ice. For comparison, we present the difference between GODAPS and GODAPS2. The verification results show that GODAPS2 yields an overall improved simulation compared to GODAPS.