• 한국환경보건학회지
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• 제32권5호
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• pp.404-411
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• 2006

이 연구의 목적은 유치원에서 총 휘발성 유기화합물의 농도를 평가하고, 총 휘발성 유기화합물 농도와 대표적인 8개 방향족 화합물의 상관관계를 조사하는데 있다. 도시에 위치한 11개 유치원의 실내와 실외에서 각각 30개, 11개의 지역시료를, 시골에 위치한 4개 유치원에서는 각각 10개, 4개의 시료를 테낙스 튜브를 이용하여 오전에 1-2시간 채취하였다. 채취한 시료는 열탈착하여 가스크로마토그래피-질량분석기로 분석하였다. 13가지 물질을 각각의 표준물질로 개별 정량하여 이중 빈번히 발견되는 8가지 방향족 유기화합물은 상관관계 평가에 사용하였다. 총 휘발성 유기화합물은 톨루엔을 기준으로 정량하였다. 도시에 위치한 유치원 실내의 총 휘발성 유기화합물 농도가 높았고, 조사 건수의 50%가 환경부 및 교육인적자원부의 가이드라인($400{\mu}g/m^{3}$)을 초과하였다. 도시지역의 유치원 실내 및 실외의 기하평균은 각각 $387.9{\mu}g/m^{3}$과 $134.9{\mu}g/m^{3}$이었고, 시골지역 유치원에서는 각각 $189.6{\mu}g/m^{3},;74.4{\mu}g/m^{3}$이었다. 톨루엔, 크실렌, 에틸벤젠, 정량한 유기 화합물 총합, 총 휘발성 유기화합물은 기하정규분포를 하였다. 벤젠, 톨루엔, 에틸벤젠, 크실렌(BTEX)은 도시에 위치한 유치원에서 농도도 높고, 총 휘발성 유기화합물중 함량도 높았고, 시골지역에서는 농도와 상대적 함량이 낮았다. 도시지역에서는 총 휘발성 유기화합물 중 BTEX의 비중이 25.2%였고 정량한 13가지 유기화합물 중에서는 35.6%를 차지하였다. BTEX 각각 개별물질은 미국 환경보호청이 제시하는 일일 노출 기준량(Reference Concentration; RfC) 보다는 현저히 낮았다. 총 휘발성 유기화합물읜 농도는 실내가 실외 보다 높았다(I/O ratio 2.5). BTEX의 상대적 함량도 실내가 실외보다 높아 실내에도 발생원이 있음을 암시하고 있다. 자료 분석결과 유치원 실내의 벤젠은 실외로부터 유입되고 있었고, 톨루엔, 에틸벤젠, 크실렌은 실외뿐 아니라 실내에서도 발생하고 있었다. 정량한 8개 화합물 각각과 총 휘발성 유기화합물의 스피어만 상관계수는 벤젠을 제외하고는 모두 유의하였다. 이중 톨루엔과 크실렌은 총 휘발성 유기화합물과 좋은 상관성 (톨루엔 0.76, 크실렌, 0.87)을 나타내었다. 이 연구는 톨루엔과 크실렌이 총 휘발성 유기화합물의 좋은 지표를 사용될 있고, 톨루엔, 에틸벤젠, 크실렌 등 많은 휘발성 유기화합물의 발생원은 실외뿐 아니라 실내에도 있음을 나타내고 있다.

• Asian Pacific Journal of Cancer Prevention
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• 제16권13호
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• pp.5385-5388
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• 2015

Background: Gastric cancer is the most common gastrointestinal cancer and a leading cause of cancer mortality in Nepal. Survival of gastric cancer patients depends on the stage at which diagnosis is made. The aim of this study was to analyze the presentation and outcomes of gastric cancer patients treated at a tertiary care hospital in Nepal. Materials and Methods: A retrospective analysis of 140 consecutive histologically proven gastric adenocarcinoma cases managed at the Department of Surgery, Tribhuvan University Teaching Hospital, Kathmandu, Nepal for the period of January 2009 to December 2013 was carried out. Results: One hundred forty out of the total 186 patients with histologically proven gastric adenocarcinoma, were admitted for surgery. The mean age was $59.6{\pm}12.4yrs$ (range 29 to 78 yrs) and the male: female ratio was 2:1. Sixty three (45%) patients featured Tibeto-Burman descent though this ethnic group accounts for only 18% of the Nepalese population. Two-thirds or more patients presented with abdominal pain, anorexia, weight loss and/or vomiting. In 86 (61.5%) of the patients the tumor was located in the lower $3^{rd}$ of the stomach and in only 15% of the patients the tumor was located at the upper $3^{rd}$. Early gastric cancer was diagnosed postoperatively in only 4%. In 54%, the disease was locally advanced and metastatic lesions were found in 14% of the patients. Subtotal (73) or total (11) curative gastrectomies (D1, D1+ or D2) were performed in 84 (60%) patients with average lymph node retrieval of $16.6{\pm}8.2$. Palliative gastrectomies or procedures were performed in 23% of the patients and no intervention (open & close/biopsy) was employed in 15% of the patients. Perioperative morbidity was seen in 10% and mortality in 4%. Three, four and five year survival rates up to the recent follow-up were 17.9%, 11.9% and 8.3%, respectively. Conclusions: Gastric cancer in Nepal is usually diagnosed at an advanced stage and has a poor prognosis. Thus, early detection is the key to improve the survival of gastric cancer patients.

• Asian-Australasian Journal of Animal Sciences
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• 제30권12호
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• pp.1702-1710
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• 2017

Objective: The study examined the effect of condensed tannins (CT) containing Ficus infectoria and Psidium guajava leaf meal mixture (LMM) supplementation on nutrient metabolism, methane emission and performance of lambs. Methods: Twenty four lambs of ~6 months age (average body weight $10.1{\pm}0.60kg$) were randomly divided into 4 dietary treatments (CT-0, CT-1, CT-1.5, and CT-2 containing 0, 1.0, 1.5, and 2.0 percent CT through LMM, respectively) consisting of 6 lambs each in a completely randomized design. All the lambs were offered a basal diet of wheat straw ad libitum, oat hay (100 g/d) along with required amount of concentrate mixture to meet their nutrient requirements for a period of 6 months. After 3 months of experimental feeding, a metabolism trial of 6 days duration was conducted on all 24 lambs to determine nutrient digestibility and nitrogen balance. Urinary excretion of purine derivatives and microbial protein synthesis were determined using high performance liquid chromatography. Respiration chamber study was started at the mid of 5th month of experimental feeding trial. Whole energy balance trials were conducted on individual lamb one after the other, in an open circuit respiration calorimeter. Results: Intake of dry matter and organic matter (g/d) was significantly (p<0.05) higher in CT-1.5 than control. Digestibility of various nutrients did not differ irrespective of treatments. Nitrogen retention and microbial nitrogen synthesis (g/d) was significantly (p<0.01) higher in CT-1.5 and CT-2 groups relative to CT-0.Total body weight gain (kg) and average daily gain (g) were significantly (linear, p<0.01) higher in CT-1.5 followed by CT-1 and CT-0, respectively. Feed conversion ratio (FCR) by lambs was significantly (linear, p<0.01) better in CT-1.5 followed by CT-2 and CT-0, respectively. Total wool yield (g; g/d) was linearly (p<0.05) higher for CT-1.5 than CT-0. Methane emission was linearly decreased (p<0.05) in CT groups and reduction was highest (p<0.01) in CT-2 followed by CT-1.5 and CT-1. Methane energy (kcal/d) was linearly decreased (p<0.05) in CT groups. Conclusion: The CT supplementation at 1% to 2% of the diet through Ficus infectoria and Psidium guajava LMM significantly improved nitrogen metabolism, growth performance, wool yield, FCR and reduced methane emission by lambs.

• 한국표면공학회:학술대회논문집
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• 한국표면공학회 1999년도 추계학술발표회 초록집
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• pp.15-15
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• 1999

In chip plating, several parameters must be taken into consideration. Current density, solution concentration, pH, solution temperature, components volume, chip and media ratio, barrel geometrical shape were most likely found to have an effect to the process yields. The 3 types of barrels utilized in chip plating industry are the conventional rotating barrel. vibrational barrel (vibarrel), and the centrifugal type. Conventional rotating barrel is a close type and is commonly used. The components inside the barrel are circulated by the barrel's rotation at a horizontal axis. Process yield has known to have higher thickness deviation. The vibrational barrel is an open type which offers a wide exposure to electrolyte resulting to a stable thickness deviation. It rotates in a vertical axis coupled with multi-vibration action to facilitate mixed up and easy transportation of components, The centrifugal barrel has its plated work centrifugally compacted against the cathode ring for superior electrical contact with simultaneous rotary motion. This experiment has determined the effect of barrel vibration intensity to the plating thickness distribution. The procedures carried out in the experiment involved the overall plating process., cleaning, rinse, Nickel plating, Tin-Lead plating. Plating time was adjusted to meet the required specification. All other parameters were maintained constant. Two trials were performed to confirm the consistency of the result. The thickness data of the experiment conducted showed that the average mean value obtained from higher vibrational intensity is nearer to the standard mean. The distribution curve shown has a narrower specification limits and it has a reduced variation around the target value, Generally, intensity control in vi-barrel facilitates mixed up and easy transportation of components, However, it is desirable to maintain an optimum vibration intensity to prevent solution intrusion into the chips' internal electrode. A cathodic reaction can occur in the interface of the external and internal electrode. $2HD{\;}+{\;}e{\;}{\rightarrow}20H{\;}+{\;}H_2$ Hydrogen can penetrate into the body and create pressure which can cause cracks. At high intensity, the chip's motion becomes stronger, its contact between each other is delayed and so plating action is being controlled. However, the strong impact created by its collision can damage the external electrode's structure thereby resulting to bad plating condition. 1 lot of chip was divided into two equal partion. Each portion was loaded to the same barrel one after the other. Nickel plating and tin-lead plating was performed in the same station. Portion A maintained the normal barrel vibration intensity and portion B vibration intensity was increased two steps higher. All other parameters, current, solution condition were maintained constant. Generally, plating method find procedures were carried out in a best way to maintained the best plating condition. After plating, samples were taken out from each portion. molded and polished. Plating thickness was investigated for both. To check consistency of results. 2nd trial was done now using different lot of another characteristics.

• 자원ㆍ환경경제연구
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• 제19권1호
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• pp.101-127
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• 2010

자연자원인 갯벌에 비시장가치평가법 중의 하나인 조건부가치평가법을 적용하여 근접효과를 검증하고자 하였다. 전국의 가구 수에 비례하여 1,000가구를 임의추출하였다. 그리고 갯벌로부터의 거주거리에 따라 30분 간격으로 I 구역에서 V구역까지 구역을 나누어서 표본을 재구성하였다. 이러한 근접효과 분석에는 모형의 적합성과 변수의 통계적 유의성을 고려하여 로그선형모형(log-linear)을 적용하였다. 일반적으로는 로짓모형이 많이 사용되지만 소득효과를 제어할 수 없기 때문에, 소득효과를 제어할 수 있는 로그선형 모형을 이용하였다. 결과를 살펴보면, 각 구간별 지불의사액의 차이를 명확하게 보여주었으며(${\theta}_1$ >0. ${\theta}_2$ >0), 또한 모형에서 더미변수들이 통계적으로 5% 유의수준에서 유의하다는 결론($dum1{\neq}0$, $dum2{\neq}0$, $dum3{\neq}0$, $dum4{\neq}0$)을 얻을 수 있었다. 실제로 개방형 설문조사에서도 I 구역 거주자들의 지불의사액이 V구역 거주자들의 지불의사액보다 약 26% 이상 크게 나타났다. 따라서 이렇게 도출된 결과로부터 비시장재화의 특징을 지닌 자연자원에 대하여 비시장가치평가법을 적용하는 경우에는 근접효과가 존재하기 때문에 설문에 이를 충분히 반영(embedded)하여야 한다는 결론을 도출하였다. 이를 통해서 좀 더 명확한 지불의사액 추정이 가능하며, 편익이전시 과소평가되는 문제를 예방할 수 있다.

• 한국작물학회지
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• 제42권3호
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• pp.323-332
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• 1997

남부지방의 답전환전에서 나물콩인 은하콩과 광안콩을 5월 15일과 6월 16일의 두 파종기를 두어 명거배수와 지표배수에서 재배하여 이에 대한 생육 및 수량을 알아 본 결과 다음과 같다. 1. 개화기까지의 경장, 마디수, 분지수는 배수처리에 따른 차이는 없었지만 답전환전이 밭보다는 짧거나 적었고, 파종기가 늦을수록 답전환전에서 길거나 많았다. 2. 개화기까지의 줄기 및 뿌리의 생체중은 배수처리에 따른 차이는 없었지만 답전환전이 밭보다는 적었고, 파종기가 늦을수록 은하콩에서 증가하였다. 3. 개화기의 줄기 및 뿌리의 생체중은 수량과 각각 고도의 정의 상관을 나타내었고, 근류수와 근류중도 고도의 정의 상관을 나타내었다. 4. 도복은 배수처리간 차이는 없었으며 5월 15일 파종보다 6월 16일 파종시 심하였고, 은하콩이 광안콩보다 덜 심했다. 5. 협수 및 100립중은 배수처리에 따른 차이는 없었으며, 100립중은 파종기가 늦을수록 은하콩은 무거웠고 광안콩은 가벼워TEk. 균일도는 5.00∼5.60mm에서 배수처리간 차이는 없었지만, 파종기가 은하콩은 늦을수록 낮아지고 광안콩은 높아지는 경향이었다. 6. 수량은 지표배수에서 명거배수보다 높았으며, 은하콩은 6월 16일 파종시에서, 광안콩은 5월 15일 파종시에서 높은 수량을 보였다.

• 한국지리정보학회지
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• 제16권3호
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• pp.54-67
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• 2013

본 연구는 근대 대구시를 대상으로 가시권분석과 토지이용현황을 분석하고 GIS를 활용하여 이를 중첩시킴과 동시에 3D 시뮬레이션으로 투시도를 작성하여 근대 대구시의 조망경관 특성을 분석하였다. 근대 대구시의 경관특성은, 가시권역에 포함된 토지이용에서 산림의 비율이 매우 높다는 점이다. 특히, 서쪽의 와룡산, 북쪽의 함지산 및 학봉, 남쪽의 앞산 등 높은 산지와 더불어 서부침식저지와 동부구릉지 및 침식저지에 형성된 산림이 낮은 구릉지 형태로 존재하고 있어서 어디에서나 산림이 조망 가능하며, 시점 주변에 농지가 분포하고 있어서 시점에서 주위 산을 조망할 때, 시야 확보가 가능하고 농지-산림으로 이어지는 자연환경 요소에 의해 연속적인 조망경관이 형성되었다. 또한, 주요 조망대상은 조사구역의 경계를 형성하고 있는 산지이며, 성내에서 경계를 형성하고 있는 산지까지의 내부공간에는 주변지역보다 표고가 높고 산림으로 구성된 조망대상이 위치하고 있어서 성내를 중심으로 서쪽, 남쪽, 북쪽 방향으로 이중구조를 지니고 있으며, 이로 인하여 중첩경관(重疊景觀)이 형성되어 있다.

• Journal of Microbiology and Biotechnology
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• 제17권9호
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• pp.1460-1468
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• 2007

In this study, an approx. 2.5-kb gene fragment including the catalase gene from Rhodospirillum rubrum S1 was cloned and characterized. The determination of the complete nucleotide sequence revealed that the cloned DNA fragment was organized into three open reading frames, designated as ORF1, catalase, and ORF3 in that order. The catalase gene consisted of 1,455 nucleotides and 484 amino acids, including the initiation and stop codons, and was located 326 bp upstream in the opposite direction of ORF1. The catalase was overproduced in Escherichia coli UM255, a catalase-deficient mutant, and then purified for the biochemical characterization of the enzyme. The purified catalase had an estimated molecular mass of 189 kDa, consisting of four identical subunits of 61 kDa. The enzyme exhibited activity over a broad pH range from pH 5.0 to pH 11.0 and temperature range from $20^{\circ}C$ to $60^{\circ}C$C. The catalase activity was inhibited by 3-amino-1,2,4-triazole, cyanide, azide, and hydroxylamine. The enzyme's $K_m$ value and $V_{max}$ of the catalase for $H_2O_2$ were 21.8 mM and 39,960 U/mg, respectively. Spectrophotometric analysis revealed that the ratio of $A_{406}$ to $A_{280}$ for the catalase was 0.97, indicating the presence of a ferric component. The absorption spectrum of catalase-4 exhibited a Soret band at 406 nm, which is typical of a heme-containing catalase. Treatment of the enzyme with dithionite did not alter the spectral shape and revealed no peroxidase activity. The combined results of the gene sequence and biochemical characterization proved that the catalase cloned from strain S1 in this study was a typical monofunctional catalase, which differed from the other types of catalases found in strain S1.

• 생태와환경
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• 제50권4호
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• pp.422-431
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• 2017

본 연구에서는 상류댐과 열린하구를 가진 소유역에서 하천을 통해 기수역에 유출되는 육상기원 유기탄소의 농도와 발생기원의 시공간적인 분포를 파악하였다. 탐진강과 강진만의 연구결과, 탐진강 상류에 건설된 댐저수지와 강진만 해양에서는 여름 강우 이전에는 일차생산에 의해 저수지 기원, 그리고 해양기원 식물플랑크톤이 유기탄소의 성상과 조성에 영향을 미쳤다. 댐하류 하천에서는 상류댐에서 유래한 물질이, 그리고 금강천이 합류되면서 지류의 영향이 나타났다. 탐진강 하구역은 조석간만에 따라 탐진강에서 공급되는 물질과 바다에서 유입되는 물질, 그리고 국지적인 갈대습지의 영향이 복잡하게 작용하여 DOC와 POC의 농도변화에 영향을 주고 있었다. 특히, 탐진강에서는 대부분의 유기탄소가 DOC 형태로 강하구로 유출되는 반면, 강진만에서는 해양으로부터 들어오는 식물플랑크톤의 영향으로 POC 형태의 공급이 우세하게 나타나는 등 유기탄소의 성상별, 발생기원별 전이가 뚜렷하게 발생하였다. 이와 같은 강과 해양으로 연결하는 하천 유기탄소의 시공간적인 변화연구는 유역의 환경변화에 따른 생태계 물질이동 변화를 평가하고 예측하는 데 활용될 수 있을 것이다.

• Journal of Chest Surgery
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• 제8권1호
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• pp.37-44
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• 1975

Authors have reviewed the records of seven patients of multiple rib fractures with severe flail chest who were admitted to Hanyang University Hospital during the 3 years period from 1972 through 1975. Of the seven patients studied, automobile accidents led to the injuries in 4 cases, two patients were injured in fall from a tree and on the ox-heading. All who had a blunt trauma without any open wound on the chest. The numbers of the fractured ribs accounted for 6 to 9 of the ribs including double fractures from 3 to 5 ribs. The left side fractures occurred in the 6 patients and in the right only one patient. Thus the flail segment was more often located in the left antero-lateral position than in the right lateral position [the ratio was 6:1].. All cases had associated injuries. The injuries and multiple fractures were the most common associated injuries occurring in four and five of the patients respectively. The patients were classified as having associated head injuries when they were admitted in comatose or semicomatose state. When a major degree of instability of the thoracic cage exists, adequate respiratory change is not possible. For this reason the tracheostomy was performed in five patients in an acutely injured patient with flail chest only after an endotracheal tube has been inserted or after an endotracheal suction. All patients had secondary complications in the pleural cavity, such as hemothorax or hemopneumothorax with or without intrapulmonary hemorrhage and subcutaneous emphysema. Therefore, closed thoracostomy was performed in five patients in the emergency room. The thoracotomy was required in four patients: immediate operation without closed thoracostomy was performed in two patients and the thoracotomy was indicated in two patients after closed thoracostomy, because of increasing intrathoracic hemorrhage. As to the fixation of the flail segments, authors employed two techniques; one was towel clip traction of the flail segments and the other was intramedullary insertion of Kirschner`s wire in to the double fractured rib fragments for the fixation of the flail segments [Kirschner`s wire fixation]. Because` of an different results in the course of treatment between two techniques, data from patients with towel clip traction was compared with those from patients with thoracotomy and Kirschner`s wire fixation of the flail segments. Of the three patients with towel clip traction, two patients required bronchoscopic toilet due to lung atelectasis which developed because of inadequate motion of thoracic cage and poor expectoration. This was in contrast to the four patients with thoracotomy and Kirschner`s wire fixation, who didn`t these complication because of adequate motion of the thoracic cage and subsequent good expectoration.