• KSII Transactions on Internet and Information Systems (TIIS)
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• v.18 no.4
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• pp.881-902
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• 2024

Fast decision support systems and accurate diagnosis have become significant in the rapidly growing healthcare sector. As the number of disparate medical IoT devices connected to the human body rises, fast and interrelated healthcare data retrieval gets harder and harder. One of the most important requirements for the Healthcare Internet of Things (HIoT) is semantic interoperability. The state-of-the-art HIoT systems have problems with bandwidth and latency. An extension of cloud computing called fog computing not only solves the latency problem but also provides other benefits including resource mobility and on-demand scalability. The recommended approach helps to lower latency and network bandwidth consumption in a system that provides semantic interoperability in healthcare organizations. To evaluate the system's language processing performance, we simulated it in three different contexts. 1. Polysemy resolution system 2. System for hyponymy-hypernymy resolution with polysemy 3. System for resolving polysemy, hypernymy, hyponymy, meronymy, and holonymy. In comparison to the other two systems, the third system has lower latency and network usage. The proposed framework can reduce the computation overhead of heterogeneous healthcare data. The simulation results show that fog computing can reduce delay, network usage, and energy consumption.

• Proceedings of the Korea Information Processing Society Conference
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• 2007.05a
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• pp.463-466
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• 2007

현재 웹 서비스에서 주로 사용하고 있는 키워드 기반 검색은 사용자의 의도와는 상관없는 정보까지 검색하는 경우가 많아서, 실제로 원하는 정보를 찾는데 많은 시간과 노력을 요구한다는 단점이 있다. 이러한 단점을 보완하기 위해서 최근 시맨틱 웹이라는 개념이 등장하였으며, 본 논문에서는 검색 결과의 신뢰성을 향상시키기 위해 온톨로지를 기반으로 시맨틱 검색시스템을 설계하였다. 본 논문에서 설계한 온톨로지 기반의 시맨틱 검색 시스템은 기능적으로 크게 두 부분으로 구성되어 있다. 즉, 자료 수집을 하는 로봇 에이전트와 온톨로지를 기반으로 자료를 검색하는 시맨틱 검색 엔진으로 구성된다. 로봇 에이전트는 자율적으로 웹을 순회하면서 자료를 수집하고 필터링하여 메타데이터 저장소로 가져오는 역할을 한다. 시맨틱 검색 엔진은 사용자의 검색 폼으로부터 전달된 정보 검색 요구사항을 기초로 시맨틱 질의어로 변환한 후, 온톨로지 저장소를 활용하여 검색한다. 시맨틱 검색 엔진은 사용자가 입력한 검색어를 시맨틱 질의어로 변환해 주는 질의처리 모듈과 사용자의 의도를 추론하여 보다 향상된 검색을 가능하게 해주는 추론(Inference) 모듈, 온톨로지를 보관해주는 온톨로지 저장소 등으로 구성된다. 본 논문에서 설계한 온톨로지 기반의 시맨틱 검색 시스템은 키워드 기반 검색에 비해 사용자가 원하는 정보를 찾는데 소요되는 시간과 노력을 줄여 주고, 사용자의 의도에 적합한 정보를 제공할 것으로 기대된다.

• Environmental Analysis Health and Toxicology
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• v.26
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• pp.10.1-10.7
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• 2011

Objects: Chironomus riparius, a non-biting midge (Chironomidae, Diptera), is extensively used as a model organism in aquatic ecotoxicological studies, and considering the potential of C. riparius larvae as a bio-monitoring species, little is known about its genome sequences. This study reports the results of an Expressed Sequence Tags (ESTs) sequencing project conducted on C. riparius larvae using 454 pyrosequencing. Method: To gain a better understanding of C. riparius transcriptome, we generated ESTs database of C.ripairus using pyrosequencing method. Results: Sequencing runs, using normalized cDNA collections from fourth instar larvae, yielded 20,020 expressed sequence tags, which were assembled into 8,565 contigs and 11,455 singletons. Sequence analysis was performed by BlastX search against the National Center for Biotechnology Information (NCBI) nucleotide (nr) and uniprot protein database. Based on the gene ontology classifications, 24% (E-value${\leq}1^{-5}$) of the sequences had known gene functions, 24% had unknown functions and 52% of sequences did not match any known sequences in the existing database. Sequence comparison revealed 81% of the genes have homologous genes among other insects belonging to the order Diptera providing tools for comparative genome analyses. Targeted searches using these annotations identified genes associated with essential metabolic pathways, signaling pathways, detoxification of toxic metabolites and stress response genes of ecotoxicological interest. Conclusions: The results obtained from this study would eventually make ecotoxicogenomics possible in a truly environmentally relevant species, such as, C. riparius.

• Journal of Ginseng Research
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• v.45 no.1
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• pp.58-65
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• 2021

Background: Panax ginseng, as one of the most widely used herbal medicines worldwide, has been studied comprehensively in terms of the chemical components and pharmacology. The proteins from ginseng are also of great importance for both nutrition value and the mechanism of secondary metabolites. However, the proteomic studies are less reported in the absence of the genome information. With the completion of ginseng genome sequencing, the proteome profiling has become available for the functional study of ginseng protein components. Methods: We optimized the protein extraction process systematically by using SDS-PAGE and one-dimensional liquid chromatography mass spectrometry. The extracted proteins were then analyzed by two-dimensional chromatography separation and cutting-edge mass spectrometry technique. Results: A total of 2,732 and 3,608 proteins were identified from ginseng root and cauline leaf, respectively, which was the largest data set reported so far. Only around 50% protein overlapped between the cauline leaf and root tissue parts because of the function assignment for plant growing. Further gene ontology and KEGG pathway revealed the distinguish difference between ginseng root and leaf, which accounts for the photosynthesis and metabolic process. With in-deep analysis of functional proteins related to ginsenoside synthesis, we interestingly found the cytochrome P450 and UDP-glycosyltransferase expression extensively in cauline leaf but not in the root, indicating that the post glucoside synthesis of ginsenosides might be carried out when growing and then transported to the root at withering. Conclusion: The systematically proteome analysis of Panax ginseng will provide us comprehensive understanding of ginsenoside synthesis and guidance for artificial cultivation.

• IE interfaces
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• v.25 no.1
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• pp.21-30
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• 2012

In the past, buyers and suppliers met each other to find common interests off-line in exhibitions and conferences, or through personal connection. These activities were time consuming and costly. With the advent of information era, these activities moved to online market places, where buyers search for suppliers with a set of keywords that are believed to be representative of their requirements. Its fundamental assumption is that all the potential candidates are registered in a certain database. However, recently buyers want to diversify suppliers due to needs of cost competitiveness or frequent new product development. To this end, instead of choosing suppliers from the supplier pool, discovering suppliers from all over the world should be emphasized. In order to enable buyers to describe their requirements and suppliers to capture their manufacturing capabilities via online market places, the semantic differences of terms between buyers and suppliers should be resolved. The paper summarizes various supplier discovery frameworks and prototype systems, which can be employed to expose domestic small-medium enterprises into global buyers in the near future.

• Genomics & Informatics
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• v.21 no.3
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• pp.36.1-36.19
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• 2023

The LIM domain-containing proteins are dominantly found in plants and play a significant role in various biological processes such as gene transcription as well as actin cytoskeletal organization. Nevertheless, genome-wide identification as well as functional analysis of the LIM gene family have not yet been reported in the economically important plant sorghum (Sorghum bicolor L.). Therefore, we conducted an in silico identification and characterization of LIM genes in S. bicolor genome using integrated bioinformatics approaches. Based on phylogenetic tree analysis and conserved domain, we identified five LIM genes in S. bicolor (SbLIM) genome corresponding to Arabidopsis LIM (AtLIM) genes. The conserved domain, motif as well as gene structure analyses of the SbLIM gene family showed the similarity within the SbLIM and AtLIM members. The gene ontology (GO) enrichment study revealed that the candidate LIM genes are directly involved in cytoskeletal organization and various other important biological as well as molecular pathways. Some important families of regulating transcription factors such as ERF, MYB, WRKY, NAC, bZIP, C2H2, Dof, and G2-like were detected by analyzing their interaction network with identified SbLIM genes. The cis-acting regulatory elements related to predicted SbLIM genes were identified as responsive to light, hormones, stress, and other functions. The present study will provide valuable useful information about LIM genes in sorghum which would pave the way for the future study of functional pathways of candidate SbLIM genes as well as their regulatory factors in wet-lab experiments.

• Proceedings of the Korean Society of Computer Information Conference
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• 2009.01a
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• pp.19-24
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• 2009

이 논문에서는 메타데이터 레지스트리 (MDR, Metadata Registry) 기반의 웹 온톨로지 생성모델을 제안한다. 메타데이터 레지스트리는 국제 표준(ISO/IEC 11179)으로서 데이터베이스간 상호운용성 향상을 위해 개발되었다. 그러나 데이터 표현과 상호운용성을 위한 컴퓨팅 환경의 변화는 메타데이터 레지스트리의 확장은 물론 메타데이터 레지스트리의 활용 방법의 변화를 요구한다. 이 논문에서의 웹 환경의 변화란 정적인 웹 환경에서 웹 2.0 혹은 시맨틱 웹 이라고 정의하는 차세대 웹 환경으로의 변화를 의미한다. 이러한 환경을 위해서 다양한 기술 개발과 적용 기법에 관한 연구가 필요하다. 특히 차세대 웹을 위해서는 지원에 대한 명확한 의미 정의 및 활용이 요구된다. 이는 웹 온톨로지 스키마를 구성하는 개념들에 대한 보다 일관성 있는 정의 및 사용이 필요하다. 이러한 문제가 해결되지 않을 경우, 또 다시 온톨로지를 구성하는 개념들 간 이질성 문제를 야기한다. 메타데이터 레지스트리는 다양한 표준화 된 개념들을 포함하며, 응용을 위한 데이터를 위한 의미 또한 이 개념들을 이용하여 정의한다. 따라서 이러한 표준 요소를 이용한 웹 온톨로지 스키마 정의 및 활용이 요구되며, 이 논문에서 이와 관련된 기본 개념, 요구 사항을 장의하고 전체적인 모델을 제안한다.

• Journal of information and communication convergence engineering
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• v.6 no.2
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• pp.117-121
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• 2008

In ad hoc network, the scarce energy management of the mobile devices has become a critical issue in order to extend the network lifetime. Therefore, the energy consumption is important in the routing design, otherwise cluster schemes are efficient in energy conserving. For the above reasons, an Energy conserving Context aware Clustering algorithm (ECC) is proposed to establish the network clustering structure, and a routing algorithm is introduced to choose the Optimal Energy Routing Protocol (OERP) path in this paper. Because in ad hoc network, the topology, nodes residual energy and energy consuming rate are dynamic changing. The network system should react continuously and rapidly to the changing conditions, and make corresponding action according different conditions. So we use the context aware computing to actualize the cluster head node, the routing path choosing. In this paper, we consider a novel routing protocol using the cluster schemes to find the optimal energy routing path based on a special topology structure of Resilient Ontology Multicasting Routing Protocol (RODMRP). The RODMRP is one of the hierarchical ad hoc network structure which combines the advantage of the tree based and the mesh based network. This scheme divides the nodes in different level found on the node energy condition, and the clustering is established based on the levels. This protocol considered the residual energy of the nodes and the total consuming energy ratio on the routing path to get the energy efficiently routing. The proposed networks scheme could get better improve the awareness for data to achieve and performance on their clustering establishment and messages transmission. Also, by using the context aware computing, according to the condition and the rules defined, the sensor nodes could adjust their behaviors correspondingly to improve the network routing.

• Annual Conference on Human and Language Technology
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• 2005.10a
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• pp.21-27
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• 2005

본 논문에서는 국가에서 추진하는 차세대신성장동력산업과 관련된 특정 분야('바이오 신약/장기' 분야 중 '면역 기능 제어')를 선택하여, 기구축된 면역학 전문용어사전을 비롯하여 의학용어사전, 표준국어대사전 등을 참조하여 핵심 용어와 관련 용어를 중심으로 면역학 시소러스(어휘 3,462개) 및 온톨로지(개념 노드 4,703개)를 구축하였다. 이것은 전문용어사전부터 온톨로지에 이르기까지 통일화된 표준 체계를 가지고 있으며, 도메인 온톨로지를 구축하여 향후 온톨로지 개발 방향을 설정할 수 있는 계기가 되었다고 할 수 있다. 또한 면역학 시소러스는 검색의 성능을 향상시킬 수 있도록 충분한 양의 데이터를 구축하였고 면역학 온톨로지는 언어처리적 관점에서의 온톨로지를 표현하였다. 이는 정보검색에서의 효율성을 비롯하여, 특정 웹 온톨로지 언어를 이용한 웹 온톨로지로의 변환성, 대규모 도메인 온톨로지라는 점에서 의미를 가진다고 할 수 있다.

• Korean Journal of Computational Design and Engineering
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• v.19 no.4
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• pp.390-401
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• 2014

ISO 15926 is an international standard for integration of lifecycle data for process plants including oil and gas facilities. From the viewpoint of information modeling, ISO 15926 Parts 2 provides the general data model that is designed to be used in conjunction with reference data. Reference data are standard instances that represent classes, objects, properties, and templates common to a number of users, process plants, or both. ISO 15926 Parts 4 and 7 provide the initial set of classes, objects, properties and the initial set of templates, respectively. User-defined reference data specific to companies or organizations are defined by inheriting from the initial reference data and the initial set of templates. In order to support the extension of reference data and templates, an editor that provides creation, deletion and modification functions of user-defined reference data is needed. In this study, an editor for reference data based on ISO 15926 was developed. Sample reference data were encoded in OWL (web ontology language) according to the specification of ISO 15926 Part 8. iRINGTools and dot15926Editor were benchmarked for the design of GUI (graphical user interface). Reference data search, creation, modification, and deletion functions were implemented with XML (extensible markup language) DOM (document object model), and SPARQL (SPARQL protocol and RDF query language).