• 한국자동차공학회논문집
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• 제24권1호
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• pp.47-52
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• 2016

Miller timing is one of the promising ways which can improve the fuel consumption of internal combustion engines. Indeed, Miller timing employing an early intake valve close is widely applied to large diesel and gas engines to enhance performance and reduce NOx emissions. In this study, performance evaluation is carried out by 1-D cycle simulation in order to estimate the effect of Miller CAM timing before BDC for a 32 L turbocharged diesel engine. To optimize Miller CAM timing, a single stage turbocharger is matched with an early intake valve close since boost pressure is a significant parameter that can control compression work in a turbocharged engine. The engine simulation result shows that there is enough potential to improve fuel consumption rate and also reduce NOx emissions at the same time.Abstract here.

• 한국자동차공학회논문집
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• 제13권4호
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• pp.145-151
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• 2005

Natural gas is one of clean fuels that can replace petroleum-based fuels, because it has low exhaust emission, comparatively high thermal efficiency and abundant deposits. In this addition, owing to high octane number and wide lean flammability limit, it has a strong point to increase the compression ratio. For this reason, the research is being actively executed to increase the generating power and thermal efficiency of the engine by raising the compression ratio through utilization of high octane number relevant to development of CNG engine. In this study, 0.63L single cylinder diesel engine has been used to alter easily compression ratio. Compression ratio has gotten under control by modifying the thickness of gasket between cylinder head and block without major structural modifications. As the result, as compression ratio has increased, generating power and fuel consumption ratio have been improved. As for emission concentration, as compression ratio has increased, THC concentration has been decreased while exhause concentration of NOx increased. In case compression ratio has excessively increased, brake output decrease and cycle variation have been increased. As the result acquired by analyzing brake output, fuel consumption ratio, cycle variation and exhaust, the engine driving condition has acquired $\varepsilon=13$ as the optimal compression ratio in this study.

• Journal of Periodontal and Implant Science
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• 제31권3호
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• pp.611-623
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• 2001

Cyclosporin A is a cyclic polypeptide produced by the metabolism of fungi. It is widely used at present as immunosuppressive treatment following organ transplants. It is also used to deal with autoimmune diseases such as rheumatoid arthritis or type II diabetes. Gingival hyperplasia is one of the most frequent side-effects associated with the prescription of Cyclosporin A. The mechanisms involved in Cyclosporin A induced gingival hyperplasia are not yet clear. In vitro Cyclosporin A promotes proliferation of gingival fibroblasts, that Cyclosporin A act as a mitogen. Its action is based on mitosis of gingival fibroblasts regulated by cell cycle regulatory proteins. It was the purpose of the present study to examine the effects of Cyclosporin A on human gingival fibroblasts by means of biological and biochemical criteria. In this present study, we examined change of cell proliferation, cell activity, cell viability and cell cycle progression after application of Cyclosporin A. We also examined expression of cell cycle regulatory proteins by western blot analysis. Human gingival fibroblasts were cultured for 48 hours with application of Cyclosporin A at concentrations of 0.01, 0.1, 1, and 10 ng/ml. Cyclosporin A(1 ng/ml) significantly increased the cell activity of gingival fibroblast. Proliferation and viability of gingival fibroblasts were also increased in group treated with 1 ng/ml of Cyclosporin A compared to control group. In the cell cycle analysis, S phase was increased and G1 phase was decreased in the group treated with 1 ng/ml of Cyclosporin A. Cyclosporin A increased the expression of cdk4 and inhibited the expression of pRB and p21. These results suggest that 1 ng/ml of Cyclosporin A may increase the cell cycle progression of human gingival fibroblasts, and its mechanisms may increase the expression of cdk4 and decrease the expression of pRB and p21.

• Membrane and Water Treatment
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• 제11권1호
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• pp.79-85
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• 2020

A single-stage deammonification with a sequencing batch reactor (SBR) that simultaneous nitritation, anaerobic ammonia oxidation (anammox), and denitrification (SNAD) occur in one reactor has been widely applied for sidestream of wastewater treatment plant. For the stable and well-balanced SNAD, a feeding strategy of influent wastewater is one of the most important operating factors in the single-stage deammonification SBR. In this study, single-stage deammonification SBR (working volume 30L) was operated to treat a high-strength ammonium wastewater (1200 mg NH₄⁺-N/L) with different feeding strategies (single feeding and nine-step feeding) under the condition without COD. Each cycle of the step feeding involved 6 sub-cycles consisted of aerobic and anoxic periods for partial nitritation (PN) and anammox, respectively. Contrary to unstable performance in the single feeding, the step feeding showed better deammonification performance (0.565 kg-N/m³/day). Under the condition with COD, however, the nitrogen removal rate (NRR) decreased to 0.403 kg-N/m³/day when the Nine-step feeding strategies had an additional denitrification period before sub-cycles for PN and anammox. The NRR was recovered to 0.518 kg-N/m³/day by introducing an enhanced multiple-step feeding strategy. The strategy had 50 cycles consisted of feed, denitrification, PN, and anammox, instead of repeated sub-cycles for PN and anammox. The multiple-step feeding strategy without sub-cycle showed the most stable and excellent deammonification performance: high nitrogen removal efficiency (98.6%), COD removal rate (0.131 kg-COD/m³/day), and COD removal efficiency (78.8%). This seemed to be caused by that the elimination of the sub-cycles might reduce COD oxidation during aerobic condition but increase the COD utilization for denitrification period. In addition, among various sensor values, the ORP pattern appeared to be applicable to monitor and control each reaction step for deammonification in the multiple-step feeding strategy without sub-cycle. Further study to optimize the number of multiple-step feeding is still needed but these results show that the multiple-step feeding strategy can contribute to a well-balanced SNAD for deammonification when treating high-strength ammonium wastewater with COD in the single-stage deammonification SBR.

• 조명전기설비학회논문지
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• 제17권2호
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• pp.73-80
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• 2003

제안된 제어 기법은 아날로그 적분기의 적분시간이 적분기 입력전압의 크기에 반비례하는 원리를 이용하여 이 펄스 변조 스위칭 컨버터를 순시 추종 제어하는 방법을 제시한다. 제안된 제어 방법은 정주파수로 동작하며 제어 스위치가 턴 온 되는 시점에서 시작하여 턴 오프 되는 시간을 아날로그 적분기를 사용하여 계산한다. 전력 변환기의 스위칭 시간을 나타내는 듀티비는 스위칭 변수의 평균치에 의하여 결정되며 추종시간은 한 사이클 내에서 이루어진다. 정상 상태는 물론 과도 상태에서도 정확하게 지령치에 추종하며, 제어기는 제어 변수의 평균치와 제어 기준값을 보정하여 제어 오차가 제로가 되게 제어한다. 제안된 제어 방법은 벅 컨버터를 사용하여 실험하였으며 이를 통하여 실험 결과와 이론이 잘 일치하고 있음을 알 수 있었다.

• 대한한방내과학회지
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• 제26권2호
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• pp.333-340
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• 2005

Background: Cancer reseach is done in earnest world-wide, because cancer is one of most threatening diseases to humans. Orostachyos Herba is a widely used herb that has long been in use in Korea as an anti-inflammatory and anti-cancer therapy. The purpose of this study is to verify any anti-cancer effects on stomach and liver cancer in vitro. Materials & Methods: AGS and KATO III stomach cancer cells and Hep3B and HepG2 liver cancer cells, all obtained from Korean Cell Line Bank, were used. The boiled extract of Orostachyos Herba(20 and 40 microliters) were injected into cultures and observed at 0 hours, and at 24-hour intervals up to 96 hours. The destruction of stomach and liver cancer cells was measured through Trypan blue exclusion testing. The suppression on viability of stomach and liver cancer cells was observed, and anti-cancer mechanisms was examined by analyzing the cell cycle. Results: In morphologic change, AGS, KATO III, HepG2 and Hep3B showed some of the withdrawn and floating appearance that is typical in cellular imparment. AGS, KATO III, HepG2 and Hep3B showed more destruction of stomach cancer cells in each test group than in the control group to a statistically significant degree. Analysis of the cell cycle after introduction of Orostachyos Herba showed very little inhibition of divisions of all cell lines. Conclusions: This experiment suggests that Orostachyos Herba has some anti-tumor effects on stomach and liver cancer cells. Progressive research on Orostachyos Herba and it's anti-tumor effects will be needed to determine its practicability as a cancer treatment.

• 한국자동차공학회논문집
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• 제21권6호
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• pp.123-134
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• 2013

Strengthening vehicle emission regulation is one of important policies to improve air quality in urban area. Due to the limitation of specified driving cycles for certification test to reflect real driving conditions, additional off-cycle emission regulations have been adopted in US and being developed in Europe. The driving cycles of US or Europe have been used in emission certification for Korean light-duty vehicles, but it has not been known how well the driving cycles reflect various real driving patterns in Korea. In that point of view, it is required to estimate vehicle emission based on real road driving conditions to raise the effectiveness of vehicle emission regulation in Korea. In this study, real driving emission measurements have been conducted for three Korean light-duty vehicles with PEMS. The driving routes consisted of urban, rural and motorway in Seoul and Incheon. The data have been analyzed with various averaging methods including moving averaging windows method and compared to emission limits set with emission certification modes applied to tested vehicles. The results have shown that the real driving pollutant emissions of a gasoline and a LPG vehicles have been ranged quite lower than those of emission limits on CVS-75 driving cycle. But real driving NOx of a light duty diesel vehicle has been considerably higher than emission limit of NEDC driving cycle. The higher than expected NOx emission of a diesel vehicle might be caused by different strategy to control EGR in real driving condition from NEDC driving.

• 한국정보통신학회논문지
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• 제21권1호
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• pp.180-186
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• 2017

본 논문에서는 무선 센서 네트워크의 센서 노드들로부터 전송되는 데이터 트래픽에 따라 낮은 지연과 높은 데이터 효율을 지원하는 새로운 MAC 프로토콜을 제안한다. 본 논문에서 제안하는 TADW-MAC은 기존의 멀티 홉 전송에서 해당 Sleep 구간에서 오직 하나의 패킷 전송만을 스케줄할 수 있는 DW-MAC의 문제점을 해결하며, 물체 트래킹(object tracking)이나 화재 감시 시스템 등의 응용에 적합한 duty cycling 메커니즘을 가진다. 이러한 응용에서는 평소에는 데이터 전송이 이루어지지 않지만, 물체의 나타남과 화재 발생 등 이벤트가 발생하는 경우에는 많은 데이터를 전송해야 하며, 낮은 지연을 요구한다[6-8]. 따라서 TADW-MAC에서는 이러한 이벤트가 발생하였을 경우에 duty cycle을 조절함으로 보다 높은 효율과 적은 에너지를 소모할 수 있다. 여러 시뮬레이션을 통해 TADW-MAC은 기존의 RMAC이나 DW-MAC에 비해 에너지 효율과 전송 지연 면에서 더 나은 성능을 보여준다.

• 한국수소및신에너지학회논문집
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• 제19권5호
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• pp.386-393
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• 2008

The Sulfur-iodine(SI) thermochemical cycle is one of the most promising methods for massive hydrogen production. For the purpose of continuous operation of SI cycle, phase separation characteristics into two liquid phases ($H_2SO_4$-rich phase and $HI_x$-rich phase) were directly investigated via Bunsen reaction. The experiments for Bunsen reaction were carried out in the temperature range, from 298 to 333 K, and in the $I_2/H_2O$ molar ratio of $0.109{\sim}0.297$ under a continuous flow of $SO_2$ gas. As the results, solubility of $SO_2$, decreased with increasing the temperature, had considerable influence on the global composition in the Bunsen reaction system. The amounts of impurity in each phase(HI and $I_2$ in $H_2SO_4$-rich phase and $H_2SO_4$ in $HI_x$-rich phase) were decreased with increasing $H_2SO_4$ molar ratio and temperature. To control the amounts of impurity in $HI_x$-rich phase, temperature is a factor more important than $I_2/H2_O$ molar ratio. On the other hand, the affinity between $HI_x$ and $H_2O$ was increased with increasing $I_2/H2_O$molar ratio.

• 해양환경안전학회지
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• 제24권3호
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• pp.325-331
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• 2018

This paper deals with the dynamical analysis of a vessel that leads to capsize in regular beam seas. The complete investigation of nonlinear behaviors includes sub-harmonic motion, bifurcation, and chaos under variations of control parameters. The vessel rolling motions can exhibit various undesirable nonlinear phenomena. We have employed a linear-plus-cubic type damping term (LPCD) in a nonlinear rolling equation. Using the fourth order Runge-Kutta algorithm with the phase portraits, various dynamical behaviors (limit cycles, bifurcations, and chaos) are presented in beam seas. On increasing the value of control parameter ${\Omega}$, chaotic behavior interspersed with intermittent periodic windows are clearly observed in the numerical simulations. The chaotic region is widely spread according to system parameter ${\Omega}$ in the range of 0.1 to 0.9. When the value of the control parameter is increased beyond the chaotic region, periodic solutions are dominant in the range of frequency ratio ${\Omega}=1.01{\sim}1.6$. In addition, one more important feature is that different types of stable harmonic motions such as periodicity of 2T, 3T, 4T and 5T exist in the range of ${\Omega}=0.34{\sim}0.83$.