• Title/Summary/Keyword: On-spot test

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Clinical Utility of Two Interferon-gamma Release Assays on Pleural Fluid for the Diagnosis of Tuberculous Pleurisy

  • Kang, Ji Young;Rhee, Chin Kook;Kang, Na Hyun;Kim, Ju Sang;Yoon, Hyoung-Kyu;Song, Jeong Sup
    • Tuberculosis and Respiratory Diseases
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    • v.73 no.3
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    • pp.143-150
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    • 2012
  • Background: The release of interferon-gamma (IFN-${\gamma}$) by T lymphocytes increases after rechallenge with Mycobacterium tuberculosis antigen, especially, at a localized site of tuberculosis (TB) infection. We aimed to compare the clincial efficacy of two commercial IFN-${\gamma}$ release assays from pleural fluid for the diagnosis in tuberculous pleurisy. Methods: We performed T-SPOT.TB and QuantiFERON-TB Gold tests simultaneously on pleural fluid and peripheral blood samples from patients with pleural effusion, in South Korea, an area with intermediate TB burden. Results: Thirty-six patients were enrolled prospectively, and tuberculous pleurisy was found in 21 patients. Both the numbers of IFN-${\gamma}$ secreting T cells and the concentration of IFN-${\gamma}$ were greater in the pleural tuberculous group, comparing with the non-tuberculous group. Moreover, in the tuberculous group, there was a significant difference in IFN-${\gamma}$ producing spot-forming cells using the T-SPOT.TB method between pleural fluid and peripheral blood. The receiver operating characteristic (ROC) curve, was the greatest for pleural fluid T-SPOT.TB test, followed by peripheral blood T-SPOT.TB test, peripheral blood QuantiFERON-TB Gold test, and pleural fluid QuantiFERON-TB Gold test (area under the ROC curve of 0.956, 0.890, 0.743, and 0.721, respectively). The T-SPOT.TB assay produced less indeterminate results than did QuantiFERON-TB Gold assay in both pleural fluid and peripheral blood. Conclusion: These findings suggest that the pleural fluid T-SPOT.TB test could be the most useful test among the IFN-${\gamma}$ release assays for diagnosing tuberculous pleurisy in an area with an intermediate prevalence of TB infection.

First Report of Leaf Spot in Fischer's Ragwort Caused by Didymella ligulariae

  • Gyo-Bin Lee;Hong-Sik Shim;Weon-Dae Cho;Wan-Gyu Kim
    • Research in Plant Disease
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    • v.29 no.1
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    • pp.60-63
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    • 2023
  • During disease surveys from 2019 to 2021, the authors frequently encountered leaf spot symptoms on Fischer's ragwort plants growing at fields at six locations of Gangwon Province, Korea. The symptoms displayed brown to dark brown, circular or irregular spots on the plant leaves. The disease surveys at the six locations revealed 1-90% of diseased leaves of the plants. Phoma sp. was dominantly isolated from the diseased leaf lesions. Seven single-spore isolates of the fungus were selected and identified as Didymella ligulariae by investigation of their cultural, morphological, and molecular characteristics. Artificial inoculation test to Fischer's ragwort leaves was conducted with three isolates of D. ligulariae. The inoculation test revealed that the tested isolates cause leaf spot symptoms in the plants similar to the natural ones. The fungal pathogen has never been reported to cause leaf spot in Fischer's ragwort. Leaf spot of Fischer's ragwort caused by D. ligulariae is first reported in this study.

Fatigue Life Evaluation of Spot Welding Including Loading Speed Effect (점용접부에서 하중속도효과를 고려한 피로수명평가)

  • ;;;;A. Shimamoto
    • Transactions of the Korean Society of Machine Tool Engineers
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    • v.12 no.1
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    • pp.32-37
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    • 2003
  • Evaluation of fatigue strength on the spot welded part is very important for strength design of spot welded steel structures. In this paper, we could get the life cycle of the spot welded part using the lethargy coefficient obtained through the quasi-static tensile shear test for the specimen welded by current 10kA. The reliability evaluation of the life cycle is completed by comparing the life cycle calculated under the constant loading rate with the life cycle obtained by dynamic fatigue test. And then the result calculated by the lethargy coefficient is verified through the lift cycle calculated using the dynamic final tensile stress formula under the increased loading speed. This way can make save the time and cost in processing of predicting the life cycle of a structure.

Effect of Temperature and Water Assumtion on Strength of Spot Welded Zine Steel Plates (점용접 아연도금판의 강도특성에 대한 온도 및 침수의 영향)

  • Seo, Do-Won;Yoon, Ho-Chel;Choi, Jun-Yong;Lim, Jae-Kyoo
    • Proceedings of the KSME Conference
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    • 2003.04a
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    • pp.358-363
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    • 2003
  • Spot welded structure is operated in diverse situation because of temperature, humidity and precipitation. In addition factors of environmental pollution such as acid rain, that courses corrosion, have the tendency to increase, But spot welded structure strength is affected by dampness and environment temperatures. Therefore, it is important to evaluate effect of temperature of spot welded part, In this study, the strength distribution of spot welded plates is evaluated about the environmental temperature of zine coated steel plates and test is conducted with welded part immersed in distilled and synthetic sea water. Specimens are immersed into water for 10, 100, 500 and 1000hours to evaluate the effects of water immersion time on tensile-shear strength under the conditions of -40, 0, 20 and $50^{\circ}C$. Strength is evaluated by tensile-shear test. The conditions of spot welding are 240kgf electrode force, 10KA welding current with 0 and 5mm clearance. From this study, spot welded specimens with clearance have lower tensile-shear strength in the distilled water or synthetic sea water comparing with spot welded specimens without clearance. And they have lower tensile-shear strength under $-40^{\circ}C$ and over $50^{\circ}C$.

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FATIGUE DAMAGE PARAMETER OF SPOT WELDED JOINTS UNDER PROPORTIONAL LOADING

  • KANG H. T.
    • International Journal of Automotive Technology
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    • v.6 no.3
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    • pp.285-291
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    • 2005
  • In this paper, the author proposes a fatigue damage parameter of spot welded joints under proportional loading. The proposed fatigue damage parameter is developed based on von Mises' equivalent stress and local structural stress at the edge of spot weld nugget. The structural stress at the edges of the weld nugget in each sheet is calculated using the forces and moments that are determined by finite element analysis. A structural equivalent stress is then calculated by von Mises' equivalent stress equation. The structural equivalent stresses are correlated to experimental fatigue life of the spot welded joints. The proposed parameter is evaluated with fatigue test data of spot welds subjected to multi axial and tensile-shear loads. Sheppard's parameter and Rupp and co-workers' parameter are also evaluated with the same test data to compare with the author's parameter. This proposed parameter presents a better correlation with experimental fatigue data than those of Sheppard's and Rupp and co-workers' parameter. The proposed parameter should be very effective for durability calculations during the early design phase since coarsely meshed finite element models can be employed.

Evaluation of Weldability on the Resistance Spot Welding of DP60 Steels for Automotive Chassis (자동차 새시용 DP60강 인버터 DC 저항 점용접의 용접성 평가)

  • Kim, I.J.;Oh, I.H.
    • Journal of the Korean Society of Mechanical Technology
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    • v.13 no.4
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    • pp.143-148
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    • 2011
  • This study analyzes the resistance spot weldability of DP60 steels. To analyze the resistance spot weldability of DP60 steels, tensile strength test and macro-section test were conducted for the resistance spot welds. Acceptable welding conditions were determined as a function of the resistance spot welding process parameters such as electrode force, welding time, and welding current. The lower limit of the welding lobe was the minimum shear tension strength for 590MPa-grade steel while the upper limit was determined whether or not expulsion was detected.

Electrode Life Test of Resistance Spot Welding on Mg Alloy Using Dome Type Electrode (돔형 전극을 사용한 마그네슘 합금 저항 점용접의 전극 수명 평가)

  • Choi, Dong-Soon;Hwang, In-Sung;Kim, Dong-Cheol;Kang, Moon-Jin
    • Journal of Welding and Joining
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    • v.31 no.6
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    • pp.27-31
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    • 2013
  • Magnesium alloy is used on parts of aircraft and electronic equipment because of the highest specific strength among the common metal materials. Recently, studies about appling magnesium alloy sheet to automotive bodies are on the increase rapidly. For application to automotive bodies, researches about characteristics of resistance spot welding of magnesium alloy sheet are essential. Magnesium alloy has low boiling point, so getting sound bead shape is difficult when appling varies welding processes. Resistance spot welding is also particular about setting optimum welding conditions because of spatter generation, pores and cracks occurrence in nugget. And life of electrodes is very short because of alloying with copper that main material of electrodes. This requires frequent dressing and replacement of electrodes and decrease in productivity of resistance spot welding on magnesium alloy. Therefore in this study, for effective analysis of changes in tensile shear load and nugget size during electrode life test, evaluate detail characteristics of resistance spot welding on magnesium alloy sheet using dome type electrode.

Fatigue Life Evaluation of Spot Weldments of SPC Sheet Including Strain Rate Effect (변형률속도효과를 고려한 일반냉연강판 점용접부의 피로수명평가)

  • Song, Joon-Hyuk;Nah, Seok-Chan;Yu, Hyo-Sun;Kang, Hee-Yong;Yang, Sung-Mo
    • Transactions of the Korean Society of Automotive Engineers
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    • v.14 no.1
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    • pp.48-53
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    • 2006
  • A methodology is described for predicting the fatigue life of the resistance spot weldment including strain rate effect. Because it is difficult to perform a physical failure test with high strain rate, an analytical method is necessary to get the mechanical properties of various strain rate, To this end, quasi-static tensile-shear tests at several strain rate were performed on spot weldments of SPC. These test provided the empirical data with the strain rate. With these results, we formulated the function of fatigue life prediction using the lethargy coefficient which is the global material property from tensile test. And, we predicted the fatigue life of spot weldment at dynamic strain rate. To confirm this method for fatigue life prediction, analytical results were compared with the experimental fatigue data.

A study on the Fatigue Life Prediction Method of the Spot-welded Lap Joint (점용접이음재의 피로수명 예측기법에 관한 연구)

  • 손일선;배동호
    • Transactions of the Korean Society of Automotive Engineers
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    • v.8 no.3
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    • pp.110-118
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    • 2000
  • For reasonable fatigue design and estimation of fatigue durability considered fatigue strength and stiffness of the automotive body structure, many fatigue data must be insured according to the shapes, materials, and welding conditions of the spot welded lap joints. However, because it is actually difficult problem, there is need to establish a new method to be able to predict its fatigue life without any additional fatigue tests. Therefore, In order to improve such problems, in this study, the maximum stress function presenting the $\delta\sigma_{1max}―\delta P$ relation was defined form the relation between $\delta\sigma_{1max}-N_f$ and ${\delta}P-N_f$. By using the fatigue data on the IB type spot-welded lap joints previously obtained from the fatigue test results, fatigue life of the spot-welded lap joint previously obtained from the fatigue test results, fatigue life of the spot-welded lap joint having a certain dimension was tried to predict without any additional fatigue tests. And, its result was verified by ${\delta}P-$N_f$ curves. Obtained conclusion are as follows, 1) a maximum stress function considered the relation of the maximum principal stress, fatigue load, and the effects of geometrical factors of the IB type spot-welded lap joint was suggested. 2) the fatigue life predicted by the maximum principal stress function and the relation of $\delta\sigma_{1max}-N_f$ was well agreed with the fatigue life obtained through the actual fatigue test result. 3) the fatigue life of the IB type spot-welded lap joint having a certain dimension is able to be predicted without any additional fatigue tests from the fatigue life prediction method by the maximum principal stress function.

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Accuracy Analysis of DEM Generated from SPOT-5 Satellite Imagery (SPOT-5 위성영상으로부터 DEM 생성 및 정확도 분석)

  • 정태식;이성순;이진덕
    • Proceedings of the Korean Society of Surveying, Geodesy, Photogrammetry, and Cartography Conference
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    • 2004.11a
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    • pp.173-178
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    • 2004
  • This paper presents photogrammetric processing to generate digital elevation models and deals with the accuracy potential of SPOT-5 HRG supermode imagery for DEM generation. The DEMs obtained from digital topographic maps of 1/5000 scale were used as the refernce DEM data. DEMs extracted from HRG dats were compared with digital topograpic map DEMs on severed test sections. And digital surface model(DSM), refering to above the ground like buildings, was produced about the test built-up area.

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