• CELLMED
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• v.10 no.4
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• pp.27.1-27.6
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• 2020

Cancer is one of the leading cause of mortality in India as well as worldwide. The management of cancer by conventional therapy has shown life threatening adverse effects. The researchers are now exploring the natural way of treatment. Unani system of medicine have rich literature for cancer and many compound formulations have been described in this system. Unani system of medicine is based on holistic approach and treat human being as a unit with natural herbs, mineral and animal origin drugs. An important compound Unani formulation (CUF) from the literature has been chosen to explore the Unani claim of its anticancer activity. The phytochemical constituents were assessed using standard phytochemical screening method. Antioxidant property of this formulation was assessed by DPPH assay. The DPPH free radical scavenging assay was carried out by colorimetric method and ascorbic acid was taken as a positive control. Three different extracts of CUF on different concentrations were used to screening on human breast cancer (BCC) MCF-7 cell line. For the estimation of in-vitro cytotoxic potency of the investigated extracts was assessed on MTT assay by using trypan blue method and paclitaxel was used as the standard. Hydro-ethanolic (HE) extract showed highest free radical scavenging activity among all extracts. DPPH Assay showed substantial antioxidant activity of these extracts in hydro-ethanol extract at 1㎍ concentration of CUF. The CUF showed antioxidant and anticancer activity. The claim made by Unani physician has been proved.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2003.06a
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• pp.1869-1872
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• 2003

As SLA(Sterealithography), SLS(Selective Laser Sintering), LOM(Laminated Object Manufacturing), FDM(Fused Deposition Modeling) etc. The FDM system the heart of a study and is developed by Stratasys co. ltd, in US., is small and cheap R.P. The material filament is heated until the material reaches a near-liquid state, it is pumped through a nozzle and become hand with a shape required, and this nozzle move pumping on the previously deposited material. Such FDM system that choice deposition type with X-Y plouter obtain in the thin continue layer by decreasing amount of extrusion or to central the injection amount when the head slow down at the corner, but in the process that fusion wax or resin become hand, deformation occur and it will affect the shape accuracy and the surface roughness. Such effect will depreciate quality and reliability of the product. Therefore, when the product made in actuality, the fundamental study on the basis geometry(surface, volume, line, angle) must be preceded and it have been research by many Free Form Fabrication. So, this basic object study purpose to obtain the fundamental geometry data and to enhance the surface roughness of the shape. And an operant can use the data for the progress of the surface roughness. This study research the estimation and application of the prototype surface roughness by adjustment the injection amount. And basie of this research, describe the pattern of prototype surface roughness and also used the result to estimate the surface of prototype.

• Proceedings of the Korea Institute of Convergence Signal Processing
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• 2003.06a
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• pp.6-9
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• 2003

In this paper, we studied on the difference of speaker adaptation according to the phoneme classification for Korean Speech recognition. In order to study of speech adaptation according to the weight of difference of phoneme as recognition unit, we used SCHMM as recognition system. And Speaker adaptation method used in this paper was MAPE(Maximum A Posteriori Probability Estimation), Linear Spectral Estimation. In order to evaluate the performance of these methods, we used 10 Korean isolated numbers as the experimental data. It is possible for the first and the second methods to be carried out unsupervised learning and used in on-line system. And the first method was shown performance improvement over the second method, and hybrid adaptation showed the better recognition results than those which performed each method. And the result of Speaker adaptation using the variable weight according to the phoneme had better than the result using fixed weight.

• Journal of Radiation Protection and Research
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• v.46 no.2
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• pp.58-65
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• 2021

Background: The evaluation of skyshine distribution, release of airborne radioactive nuclides, and soil activation and groundwater migration were required for radiological assessment of the impact on the environment surrounding In-Flight (IF)-system facility of the RAON (Rare isotope Accelerator complex for ON-line experiment) accelerator complex. Materials and Methods: Monte Carlo simulation by MCNPX code was used for evaluation of skyshine and activation analysis for air and soil. The concentration model was applied in the estimation of the groundwater migration of radionuclides in soil. Results and Discussion: The skyshine dose rates at 1 km from the facility were evaluated as 1.62 × 10^-3 μSv·hr^-1. The annual releases of ³H and ¹⁴C were calculated as 9.62 × 10^-5 mg and 1.19 × 10^-1 mg, respectively. The concentrations of ³H and ²²Na in drinking water were estimated as 1.22 × 10^-1 Bq·cm^-3 and 8.25 × 10^-3 Bq·cm^-3, respectively. Conclusion: Radiological assessment of environmental impact on the IF-facility of RAON was performed through evaluation of skyshine dose distribution, evaluation of annual emission of long-lived radionuclides in the air and estimation of soil activation and groundwater migration of radionuclides. As a result, much lower exposure than the limit value for the public, 1 mSv·yr^-1, is expected during operation of the IF-facility.

• Journal of the Korean Society for Railway
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• v.19 no.3
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• pp.380-387
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• 2016

Considering that the Seoul subway sector is expected to see extension of lines, addition of stations, and changes of operating companies, a review is needed to identify ways to eliminate or minimize financial deficits in its operation. As for deficits from the operation, additional businesses for extra income have been suggested as alternatives, but inasmuch as Western urban development (that of the subway containment area) may not be applicable to Korean settings, a practical alternative is to maximize income by efficient use of rental facilities that are located inside station properties. This alternative requires the estimation of appropriate facility size and rent for each station; few, however, have addressed this topic. At this juncture, this study aimed to draw an equation for estimating the sizes and rents of station properties by reflecting characteristics of lines and locations; a case study was performed for Subway Lines 5 and 6. Analytical findings are that rental facility sizes and rental incomes are affected mainly by the subway ridership and transport revenues, whereas the influence of ground-level commercial activity is relatively weak. A particularly great influence was found to be the value of apartment housing in areas through which the subway lines run. Stations on Line 5, which runs through areas of high-value housing, were assigned smaller facility sizes and higher rents than those on Line 6, which covers areas with relatively low housing value. The equation suggested in this study would make possible more practical feasibility studies when the need arises to estimate sales of new or extended facilities affiliated with stations.

• Current Research on Agriculture and Life Sciences
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• v.4
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• pp.114-118
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• 1986

The study was conducted to find out the gene effects on litter size and birth weights in mice with 362 progenies from full-diallel crosses of four lines of BALB/c, CBA, C3H and C57BL. The progenies were farrowed at the Experimental Animal Farm, College of Agriculture, Kyungpook National University in November, 1984, and data were analyzed into general combining ability, specific combining ability and reciprocal effects with Griffing's model. General combining ability effects estimated in line-crosses were -0.4163~0.3337 for litter size and -0.0356~0.0894 for birth weights. However, no significant differences were observed in general combining ability effects on litter size and birth weights. Specific combining ability effects estimated in line-crosses were -1.0388~1.7913 for litter size and -0.1144~0.1343 for birth weights. However, the specific combining ability effects for litter size and birth weights appeared to be insignificant. The reciprocal effects, which appeared to be significant, were -2.26 from BALB/c ${\times}$ C3H, 1.84 from CBA ${\times}$ C57BL and -1.50 from BALB/c ${\times}$ CBA for litter size. For birth weights, the reciprocal effects were estimated -0.26 from CBA ${\times}$ C57BL, 0.15 from BALB/c ${\times}$ CBA and -0.15 from BALB/c ${\times}$ C57BL.

• Journal of the Korean Society for Railway
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• v.14 no.3
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• pp.222-227
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• 2011

The dropper supports the contact wire and is attached using various types of dropper clips on the catenary. Droppers are subject to mechanical stress from buckling during the passage of pantographs. In order to investigate failure causes for the high speed line dropper, theoretical analyses and experiments have been carried out. In this paper, mathematical formulas are derived for the pre-sag of the dropper static load. The measured values in the experiment were similar to the theoretical predictions. To analyze the cause on fracture of dropper wire, we have conducted analysis such as SEM(Scanning Electron Microscope) of fractured specimens in the field and new specimens. Finally, we performed measurement for the variation of dynamic load on the dropper when a pantograph moved at 300km/h under the Korean high speed overhead line. If such mechanical load occur repeatedly with every passing pantograph, it is possible that the dropper wire will break due to fatigue. This results will be used for special management of high speed catenary system maintenance and life estimation of dropper.

• Nuclear Engineering and Technology
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• v.52 no.2
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• pp.296-307
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• 2020

Permanent magnet sodium flowmeter (PMSF) have been used to measure the sodium flow in fast breeder reactors. Due to the effects of irradiation, thermal cycling, time lapse, etc., the magnetic flux density of the PMSF will decrease after being used in the reactor for a period of time. Therefore, it must be calibrated regularly. But some flowmeters that immersed in sodium cannot be removed for an off-line calibration, so the on-line calibration is required. However, the best online calibration accuracy of PMSF using cross-correlation analysis method was 2.0-level without considering the repeatability. In order to further improve this work, the operational principle of the transducer in PMSF is analyzed and the design principle of the transducer is proposed. The transducers were tested on the sodium flow loop to collect the experimental data. The signal characteristics are analyzed from the time and frequency domains, respectively. The cross-correlation analysis method based on biased estimation is adopted to obtain the flow rate. The verification experimental results showed that the measurement accuracy is 1.0-level when the flow velocity is above 0.5 m/s, and the measurement accuracy is 3.0-level when the flow velocity is in the range of 0.2 m/s to 0.5 m/s.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.27 no.11
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• pp.1986-1996
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• 2003

Methodology based on the elastic-plastic fracture mechanics has been widely accepted in predicting the critical crack length(CCL) of pressure tubes of CANDU nuclear plants. A conservative estimate of CCL is obtained by employing the J-resistance curves measured with the specimens satisfying plane strain condition as suggested in the ASTM standard. Due to limited thickness of the pressure tubes the curved compact tension(CT) specimens taken out from tile pressure tube have been used in obtaining J-resistance curves. The curved CT specimen inevitably introduce slant fatigue crack during precracking. Hence, effect of specimen geometry and slant crack on J-resistance curve should be explored. In this study, the difference of J integral values between the standard CT specimens satisfying plane strain condition and the nonstandard curved CT with limited thickness (4.2mm) is estimated using finite element analysis. The fracture resistance curves of Zr-2.5Nb obtained previously by other authors are critically discussed. Various finite element analysis were conducted such as 2D analysis under plane stress and plane strain conditions and 3D analysis for flat CT, curved CT with straight crack and curved CT with slant crack front. J-integral values were determined by local contour integration near the crack tip, which was considered as accurate J-values. J value was also determined from the load versus load line displacement curve and the J estimation equation in the ASTM standard. Discrepancies between the two values were shown and suggestion was made for obtaining accurate J values from the load line displacement curves obtained by the curved CT specimens.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.18 no.4
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• pp.97-104
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• 2018

In the conventional direction finding, the antenna is installed at a high position on the ground to detect the position of the target with the environment of the LOS(Line of Sight) as much as the signal receiving environment. However, in order to configure such environment, high cost and installation time were required. In this paper, we use TDOA(Time Difference of Arrival) technique to utilize drones in direction finding, so that four drones can be used for directions finding simulation. Simulations based on drone and TDOA direction finding were constructed using additional signal processing Taylor series and Exact Interactive Algorithm. In the simulation, the receiving power is defined by using the 800MHz path-loss model using the GPS information of the ground direction detection, and the position estimation performance is analyzed when the TDOA technique, the Taylor series, and the Exact Interactive Alogrithm are applied.