• Journal of the Korean Wood Science and Technology
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• v.8 no.3
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• pp.64-76
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• 1980

Fig. 8 summarizes the present status of high yield pulp production and the directions of research on modification. A thick line indicates pulping process presently in use. As mentioned previously, one kind of modification is to introduce hydrophilic groups onto the pulp. Still unsolved is whether or not the introduction of hydrophilic groups should be restricted to lignin only. Goring (28) reported that middle lamella lignin has fewer phenolic hydroxyl groups than cell wall lignin and suggested that such a difference in the lignin may be useful in the removal of middle lamella lignin. The introduction of hydrophilic groups onto pulp may not be enough to modify high yield pulp. The removal of some portion of carbohydrate may be also necessary from the standpoint of softening of pulp fibers. There is no information at what lignin and carbohydrate, and how much should be removed. The combination with synthetic high polymers may also be important in modifying high yield pulp. Prof. C. Schuerch of the State University of New York who was a visiting professor at the University of Tokyo in 1974, mentioned that the hydrophilicity of lignin would be promoted, if phenolic hydroxyl or carboxyl groups could be introduced into the aromatic nucleus of lignin. If this were possible. this process would also mean a pulp yield of more than 100%. This idea is just one example of the expectation made possible through lignin chemistry. Instead of the introduction of hydrophilic group, the oxidative degradation of aromatic nucleus of lignin may also be useful in promoting the hydrophilicity of pulp. In this case, ozone may be an excellent chemical. However, there are a lot of problems to be solved such as homogeneity of reaction and selectivity of ozone for lignin. The above ideas are summarized in Fig. 9. There are many problems to be solved in the production of an excellent high yield pulp which is comparable to chemical pulp. The information from wood chemistry hopefully will elucidate some of the problems mentioned above.

• Journal of Life Science
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• v.21 no.6
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• pp.912-922
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• 2011

Cancer-testis (CT) antigens are immunogenic protein antigens with restricted expression in the testes and a wide range of human tumor types, eliciting both humoral and cellular immune responses in cancer patients. They are considered to be ideal targets for vaccine-based immunotherapy, and more than 100 CT antigens, including MAGE, NY-ESO-1, GAGE, BAGE, LAGE, SSX2 and NY-SAR-35 have been identified to date. The CT antigens were identified through various techniques and can be divided in those that are encoded on the X chromosome, the CT-X genes, and those that are not, the non-X-CT genes. CT genes are aberrantly activated and expressed in a proportion of various types of human cancers. The biological role of CT-X in both germ line tissues and tumors remains poorly understood. Cancer vaccine trials based on several CT antigens are currently ongoing. This paper reviews recent advances in and future trends of CT antigens for cancer immunotherapy.

• Journal of the Korean Society of Food Culture
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• v.34 no.6
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• pp.719-725
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• 2019

This study examined the relative importance and the effective utility of fermented milk by consumers. The questionnaire was developed by an in-depth interview and literature review and was surveyed on-line. Statistical analysis was carried out descriptive analysis, ANOVA, paired t-test, and conjoint analysis using the SPSS package. First, an analysis of the consumption status of fermented milk found that the consumption frequency was 1-2 times/week (36.2%), 3-4 times/week (26.5%). The product choice attributes of fermented milk were found to be the same with 'taste' (3.93) and 'manufacturing date/expired date' (3.92), rated the highest, followed in order by, 'sanitary quality' (3.82), 'origin of ingredient' (3.81). Comparative analysis of the importance and satisfaction level of the choice attributes of fermented milk showed that the choice attributes with lower satisfaction compared to importance were 'taste', 'nutrients', 'manufacturing data/expired date', 'sanitation quality', 'price', 'manufacturing method' and 'certification of quality' (p<0.001, p<0.01). 'Price' and 'certification of quality' were the choice attributes of fermented milk classified as 'Focus Here' because of its high importance and low satisfaction. The preferred combination of relative importance in choice attributes of the fermented milk was 'domestic resource', 'Eat with spoon', and 'none additives'. Therefore, it is believed that sales will increase if dairy companies can improve the 'price' and 'certification of quality'. In addition, the use of domestic ingredients in the development of new fermented milk products in the future could be an important marketing factor in consumer choice.

• Advances in pediatric surgery
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• v.8 no.1
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• pp.41-47
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• 2002

Abnormal distribution of the enteric nerves such as adrenergic, cholinergic and peptidergic nerves may cause the functional obstruction in Hirschsprung's disease (HD). Although the sustained contraction of the aganglionic segment is the main pathophysiology of HD, the etiology and pathogenesis is not thoroughly understood, With the recent progress of molecular biology and genetics,a more detailed approach to the pathogenesis of the HD can be undertaken. In this review, the roles of the nitric oxide, nitric oxide synthase and interstitial cells of Cajal on smooth muscle relaxation, the effects of extracellular matrix, cell adhesion molecules, neurotrophic factors on the migration and maturation of the neural crest cells are described. In the section of genetic factors, familial occurrences, association of chromosomal abnormalities, RET gene, glial cell line-derived neurotrophic factor gene, endothelin-3 gene and endothelin-B receptor gene and their r elationships to HD is briefly reviewed.

• Journal of Sasang Constitutional Medicine
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• v.20 no.2
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• pp.21-29
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• 2008

1. Objectives and Methods It has been examined 703 papers of Sasang Constitution Society published from 1989 to 2007. Among them, the study methods have been classified focused on 332 papers related to clinical research and the method of constitution diagnosis and subjects have been researched to research the reality of the clinical research of Sasang Constitutional Medicine. 2. Results 1. The rest studies are the most which can not be classified by existing study method among 332 clinical studies. 2. The study of patient control group is 17 cases and the clinical experiment is one case, so highly well-grounded studies have not been performed. 3. The most method of constitution diagnosis is the constitution diagnosis by experts and by QSCC. 4. The number of constitution diagnosis method performed in the research institution is within 2. They are 254 cases(89.5%). 5. The studies which utilize more than 3 constitution methods are 22 cases and the studies that use medical rash are 7cases(31.8) 6. The 215 cases that subjects are less than 100 are the most and 100${\sim}$500 subjects are 71 cases. 500${\sim}$10000 subjects are 33 cases and more than 1000 subjects are 15 cases. 3. Conclusions Therefore, it is needed to increase the rate of highly well-grounded studies and set the standard criteria by providing constitution diagnosis guideline.

• International Commerce and Information Review
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• v.13 no.1
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• pp.271-298
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• 2011

This paper seeks the proper and efficient operation of Korea's safeguard mechanism by examining the judicial interpretation and application of the safeguard measures under the WTO Safeguard Agreement. The judicial examination is focused on the terms of "unforeseen development" in GAIT XIX, "evaluation of all relevant factors", and "clear justification of measure" in Safeguard Agreement. Such an intensive examination. of the judicial interpretation is used for the comparative analysis of the Korea's domestic provisions to find out problems in operation and the interpretative and legislative responses to them. It is found that the Korea's adaptation of the Safeguard Agreement into the domestic provisions and the operation of such provisions in the practical field have generally been consistent with the WTO's basic principles and provisions. Korea's safeguard mechanisms should stably be operated for securing the proper protection of domestic industry under certain emerging circumstances. For such policy objective to be ensured, it is legislatively required to make additional provisions in line with the appellate body's consistent interpretations of the debating issues including the term of unforeseen development.

• Proceedings of the CALSEC Conference
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• 1999.07a
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• pp.277-299
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• 1999

Since Chrysler Motor Co. had experienced the digital development system in the beginning of 1990's, most of leading automobile companies are trying to apply a digital information system for their own business process reengineering based upon concurrent engineering system from product planning phase. This is called as virtual DMU(Digital Mock-Up) system instead of the traditional PMU(Physical Mock-Up) system. By using the virtual prototype, all of the design requirements and system specifications can be checked, changed and optimized more quickly and more efficiently. This paper consists of five chapters for the DMU information system. In the 1$^{st}$ chapter, the principle of digital design system is suggested by using four basic modules such as product design module, process design module, manufacturing system design module and central control module. The basic scheme of DMU is introduced with the benefits of application in the chapter 2. In the chapter 3, a digital design process of new car development is explained with the detailed DMU design and design review processes. In the chapter 4, the practical DMU manufacturing techniques and applications are introduced as CAD/CAM analyses, DPA(Digital Pre-Assembly)reviews for development, production, operation and maintenance phases, digital tolerance analyses and digital factory analyses for assembling line simulation, automated robot welding processes, production jig ＆ fixtures and painting process simulation. Finally, the activities of digital design support; CAS-styling, CAE-engineering and CAT-testing are summarized for design optimization in the chapter 5. As today's automobile manufactures and related business organizations are struggling to compete in the global marketplace, they are concentrating on efficient use of DMU information system to reduce the new car development cost, to have shorten the delivery schedule and to improve product design quality. To meet the demand of those automobile industries on digital information systems, the CALS(Computer aided Acquisition and Logistics Support) and EC(Electronic Commerce)initiative has been focused as a dominant philosophy in defense ＆ commercial industries, specially automobile industries.s.

• Journal of Fashion Business
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• v.23 no.6
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• pp.86-100
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• 2019

This study analyzed the characteristics of vegan fashion produced by H&M and ZARA with respect to materials, design, development, production, and marketing to create social value. The results of this study are significant because they can be used as a reference to develop a vegan fashion market. Regarding the research method, this study assessed the concept and status of veganism through a literature review and examined vegan fashion case studies by analyzing official websites and media content. The study's scope covers the period from 2005, when H&M was the first SPA brand to create a vegan product line, until 2019. The characteristics of Global SPA's vegan fashion were as follows. Regarding materials, alternative materials were developed and an expanded use of organic materials was implemented. Regarding design, development was achieved through design collaboration and upcycling. In terms of production, an animal welfare policy was adopted and a sustainable supply chain was established. Marketing employed a campaign aimed at encouraging increased consumer participation. The findings regarding the social value of H&M and Zara's vegan fashion were as follows. First, a cyclical economy was realized through circular recycling in the entire process of resource selection, production, and waste disposal. Second, because product consumption indicated the importance of ethical consumption and sustainable consumer participation, corporate financial activities were created based on shared values to accomplish the social outcome. Third, collaborations with luxury brands or vegan fashion designers built a collaborative ecosystem in which vegan fashions were released and consumer participation campaigns were implemented.

• Journal of the Korean housing association
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• v.24 no.3
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• pp.121-133
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• 2013

The purpose of this study is to analyze the design characteristics of external appearances of Hundertwasser's housing projects through both literature review and field study, and to understand how Hundertwasser's architecture philosophy was embodied in the design of external appearances so such projects. The subjects of the analysis are: Hundertwasser House; In the Meadow Bad Soden; The Forest Spiral Darmstadt; and The Green Citadel Magdeburg. The conclusion of the study is as follows. The fundamental architecture philosophy of Hunderwasser is the close linkage between mankind and nature. He has proven, through his four housing projects mentioned above, that it is possible to build houses without destroying and in harmony with nature. Hundertwasser had identified vitality, irregularity and diversity as being the source of beauty of nature. Using the human creativity, he had embodied such elements into his housing projects, thus suggesting an ideal housing environment whereby humanity is respected. Hundertwasser made use of organic curved line and spiral shapes that exist in nature when designing his housing projects. His creativity was articulated through vitality, diversity, and irregularity in colour schemes and a wide range of form. Indeed, he was an architect pursuing the underlying nature of both human and nature. The current living environment in Korea can be characterized as being standardized and desolate, which is a result of housing projects being focused too much on functionalism. Through its analysis of Hundertwasser's housing projects, one of the objectives of this study is to contribute to a new design paradigm being called for today, including for housing projects to be more ecological and environmental-friendly. By motivating architects and appealing to their clients, this study hopes to motivate those involved in various housing projects to think progressively. Such an attitude change could assist in transforming and thus enhancing the overall living environment in Korea.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.2
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• pp.1426-1433
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• 2015

CCTV-applied monitoring is an effective measure to suppress potential crimes and record objective relationship; however, there is no methodology that can quantitatively compare and assess the afore-mentioned effects. Thus, this study intended to construct the methodology and analysis application that can measure the changes in the space-corresponding performance of CCTVs depending on installation measures by using 3-dimenstional virtual simulation technology. For analysis, the raster-based Isovist theory was 3-dimensionally expanded and the amount of incident sight line to each point was accumulated. At the same time, the amount of overlapped monitoring in the CCTV cameras that were connected to each measurement node was accumulated for cross-analysis. By applying the examples and analyzing the results, it was possible to construct an analysis application in use of collision detection model and quantify the changes of monitoring performance depending on positioning alternative of the cameras. Moreover, it enabled intuitive review and supplementation by reproducing visible shadow areas in a graph.