• Title/Summary/Keyword: On-Center

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Proteomic and Immunological Identification of Diagnostic Antigens from Spirometra erinaceieuropaei Plerocercoid

  • Lu, Yan;Sun, Jia-Hui;Lu, Li-Li;Chen, Jia-Xu;Song, Peng;Ai, Lin;Cai, Yu-Chun;Li, Lan-Hua;Chen, Shao-Hong
    • Parasites, Hosts and Diseases
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    • v.59 no.6
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    • pp.615-623
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    • 2021
  • Human sparganosis is a food-borne parasitic disease caused by the plerocercoids of Spirometra species. Clinical diagnosis of sparganosis is crucial for effective treatment, thus it is important to identify sensitive and specific antigens of plerocercoids. The aim of the current study was to identify and characterize the immunogenic proteins of Spirometra erinaceieuropaei plerocercoids that were recognized by patient sera. Crude soluble extract of the plerocercoids were separated using 2-dimensional gel electrophoresis coupled with immunoblot and mass spectrometry analysis. Based on immunoblotting patterns and mass spectrometry results, 8 antigenic proteins were identified from the plerocercoid. Among the proteins, cysteine protease protein might be developed as an antigen for diagnosis of sparganosis.

A 90-day repeated-dose oral toxicity study on Chelidonium majus extract in Fischer 344/N rats (백굴채(Chelidonium majus) 추출물의 Fischer 344/N 랫드를 이용한 90일간 반복 경구투여 독성시험)

  • Kim, Do-Hyung;Zhang, Hu-Song;Kim, Kwang-Ho;Kang, Sang-Chul;Kim, Hak-Soo;Gil, Ki-Hyun;Kong, Kwang-Han;Ahn, Tae-Hwan;Bae, Jin-Sook;Go, Hyeon-Kyu;Kim, Kap-Ho;Park, Chan-Koo;Lee, Hyun-Kul;Song, Si-Whan;Han, Zhong-Ze
    • Korean Journal of Veterinary Research
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    • v.49 no.1
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    • pp.23-34
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    • 2009
  • This study was performed to evaluate repeated-dose oral toxicities of Chelidonium majus extract in Fischer 344/N rats. Chelidonium majus extract was administered orally to rats at dose levels of 0, 25, 74, 222, 666 and 2,000 mg/kg/day. Each group consisted of 10 rats of each gender. The Chelidonium majus extract was given once a day, 5 times a week, for 90 day repeatedly. This study was conducted in accordance with the Protocol of Korea National Toxicology Program (issued by National Institute of Toxicological Research) and The Standards of Toxicity Study for Medicinal Products (issued by Korea Food and Drug Administration). In the present study, There were no toxicologically significant changes in mortality, clinical signs, body weight gains, ophthalmoscopy, urine analysis, hematology, serum biochemistry, necropsy findings, organ weights, histopathology, estrus cycle and sperm examination of all animals treated with Chelidonium majus extract. These results suggest that the oral no observed adverse-effect level of the test item, Chelidonium majus extract, in rats is higher than 2,000 mg/kg/day in both genders. The target organs were not established.

Progress on Proton Therapy Facility Project in National Cancer Center, Korea

  • Kim, Jong-Won;Park, Sung-Yong;Park, Dahl;Kim, Dae-Yong;Shin, Kyung-Hwan;Cho, Kwan-Ho
    • Proceedings of the Korean Society of Medical Physics Conference
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    • 2002.09a
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    • pp.180-182
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    • 2002
  • A Proton Therapy Center was established this year in National Cancer Center, Korea. We chose IBA of Belgium as the vendor of the equipment package. A 230 MeV fixed-energy cyclotron will deliver proton beams into two gantry rooms, one horizontal beam room, and one experimental station. The building for the equipment is currently under design with a special emphasis on radiation shielding. Installation of equipments is expected to begin in September next year starting with the first gantry, and the acceptance test will be performed about a year later. To generate therapeutic radiation fields the wobbling method will be a main treatment mode for the first gantry. A pencil beam scanning system on the other hand will be equipped for the second gantry relying on the availability at the time of installation. The beam scanning with intensity modulation adapted will be a most advanced form in radiation therapy known as IMPT. Some details on the project progress, scope of the system, and design of building are described.

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Printed polymer and a-Si TFT backplanes for flexible displays

  • Street, R.A.;Wong, W.S.;Ready, S.E.;Chabinyc, M.L.;Arias, A.C.;Daniel, J.H.;Apte, R.B.;Salleo, A.;Lujan, R.;Ong, Beng;Wu, Yiliang
    • 한국정보디스플레이학회:학술대회논문집
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    • 2005.07a
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    • pp.697-699
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    • 2005
  • The need for low cost flexible TFT display backplanes has focused attention on new processing techniques and materials. We have developed backplane technology based entirely on jet-printing, using a combination of additive and subtractive processing, and have applied this technique to both amorphous silicon and polymer TFT arrays.

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A Clinical Report on a Patient with Type 2 Diabetes

  • Shin, Ae-sook;Gwak, Ja-young;Cho, Seung-yeon;Lee, In-whan;Kim, Hye-mi;Kim, Na-hee;Park, Sung-wook;Park, Jung-mi;Ko, Chang-nam;Bae, Hyung-sup
    • The Journal of the Society of Stroke on Korean Medicine
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    • v.10 no.1
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    • pp.68-73
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    • 2009
  • Type 2 diabetes mellitus (T2DM) is a progressive disorder caused by a combination of insulin resistance and 𝛽 cell dysfunction. Sogal(消渴) is a traditional Korean medical term referring to a condition pertaining 3 major symptoms - thirst, polyphasia, polyuria. Sogal has been reported to have similar characteristics with DM. This case report demonstrates a patient with T2DM complaining of typical Sogal symptoms. We diagnosed him as So-yang person Sogal and treated him with acupuncture and herbal medicine.

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Verification of Periodical Calibration for Iso-center Positions using Quality Assurance System for Irradiation Equipment Position Established at PMRC

  • Yasuoka, Kiyoshi;Ishikawa, Satoko
    • Proceedings of the Korean Society of Medical Physics Conference
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    • 2002.09a
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    • pp.192-194
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    • 2002
  • We present the results on the calibration of iso-center positions using the quality assurance system established at PMRC for determination of center position in X-ray and proton irradiation fields. Details on the system are presented in another presentation in this session. The equipment in the system is mounted on a patient treatment bed in each proton exposure room, G1 or G2. A center of a stainless ball on the equipment is set at a cross of laser markers located around the iso-center and fixed on the room and on the snout in the gantry. A proton beam or an X-ray beam is exposed onto the ball through a brass collimator of 100 mm ${\times}$ 100 mm and projected onto the imaging plate set at I cm behind the ball. On the axis perpendicular to the thrust axis of the gantry on the imaging plate, a distance between a center of the collimator image and a center of the ball image varies as a cosine function of gantry angles unless the ball is set on the iso-center. An amplitude of the cosine curve shows the distance between the ball and the iso-center, an offset the offset of the collimator, and a phase shift at a zero crossing point the ball direction viewed from the iso-center. We present the relation among the iso-center position, the laser maker position, and the center of proton and X-ray irradiation fields. Its stability and its reproducibility are discussed.

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Effect of electrical aging on emission stability of carbon nanotube paste

  • Park, J.H.;Moon, J.S.;Jeong, J.S.;Yoo, J.B.;Park, C.Y.;Moon, H.S.;Nam, J.W.;Kim, J.M.;Park, J.H.;Choe, D.H.
    • 한국정보디스플레이학회:학술대회논문집
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    • 2005.07b
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    • pp.1466-1469
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    • 2005
  • We report effects of electrical aging on the emission stability of carbon nanotube (CNT) paste for low cost and high low-cost and large area field emission devices or displays. Photosensitive carbon nanotube paste was formulated by using of spin on glass (SOG) as an inorganic binder and investigated emission properties and stability depending on electrical aging condition.

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Study of the Center of Gravity in the Human Body and each Segment (인체 중심과 분절 중심에 대한 연구)

  • Chung Hyung-Kuk;Bae Sung-Soo
    • The Journal of Korean Physical Therapy
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    • v.5 no.1
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    • pp.61-69
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    • 1993
  • It was performed to encourage for Physical Therapist to apply the theory of center of the human body and segments in clinical situations. This study was investigated literarily on center of the human body and segments. Methods which search for the center-2 types, that is, method using reaction broad and segmental method-was suggested. The center location difference of gravity in human body depends on individual character. Generally, the center location is in kent of 2nd sacrum, that is, at $55\%$ of height from foot. The center of each segment is on 'link'. In the first place we must how the weight of segment we can search for the center easily. Mean segment coater location of extremities is at $42.33\%$ from each proximal end, and mean center of head and trunk lies at $45\%$.

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Influence of Sustain Pulse-Width on the Electro-Luminous Efficiency in AC-PDPs

  • Cho, T.S.;Kim, T.Y.;Kim, S.S.;Cho, D.S.;Kim, J.G.;Ahn, J.C.;Jung, Y.H.;Lim, J.Y.;Jung, J.M.;Ko, J.J.;Kim, D.I.;Lee, C.W.;Seo, Y.;Cho, G.S.;Choi, E.H.
    • 한국정보디스플레이학회:학술대회논문집
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    • 2000.01a
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    • pp.115-116
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    • 2000
  • Influence of sustain pulse-width on electro-luminous efficiency is experimentally investigated for surface discharge of AC-PDP. It is found that the firing voltage is decreased as the pulse-width is increased from $2\;{\mu}s$ to $8\;{\mu}s$ with sweeping frequency range of 10 kHz to 50 kHz. It has been found that the optimal sustain pulse-width is in the range of $3{\sim}4\;{\mu}s$ under driving frequency range of 30 kHz and 50 kHz, based on observations of memory coefficient, wall charge, and wall voltage as well as luminous efficiency.

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