• 제목/요약/키워드: On-Body System

검색결과 5,706건 처리시간 0.037초

구강 편평세포암종에서 $P16^{ink4}$ 유전자의 Methylation에 대한 연구 (($P16^{ink4}$ Methylation in Squamous Cell Carcinoma of the Oral Cavity.)

  • 강진원;김경욱;류진우;김창진
    • Maxillofacial Plastic and Reconstructive Surgery
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    • 제22권2호
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    • pp.164-173
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    • 2000
  • The p16 protein is a cyclin dependent kinase inhibitor that inhibits cell cycle progression from $G_1$ phase to S phase in cell cycle. Many p16 gene mutations have been noted in many cancer-cell lines and in some primary cancers, and alterations of p16 gene function by DNA methylation have been noticed in various kinds of cancer tissues and cell-lines. There have been a large body of literature has accumulated indicating that abnormal patterns of DNA methylation (both hypomethylation and hypermethylation) occur in a wide variety of human neoplasma and that these aberrations of DNA methylation may play an important epigenetic role in the development and progression of neoplasia. DNA methylation is a part of the inheritable epigenetic system that influences expression or silencing of genes necessary for normal differentiation and proliferation. Gene activity may be silenced by methylation of up steream regulatory regions. Reactivation is associated with demethylation. Although evidence or a high incidence of p16 alterations in a variety of cell lines and primary tumors has been reported, that has been contested by other investigators. The precise mechanisms by which abnormal methylation might contribute to carcinogenesis are still not fully elucidated, but conceivably could involve the modulation of oncogene and other important regulatory gene expression, in addition to creating areas of genetic instability, thus predisposing to mutational events causing neoplasia. There have been many variable results of studies of head and neck squamous cell carcinoma(HNSCC). This investigation was studied on 13 primary HNSCC for p16 gene status by protein expression in immunohistochemistry, and DNA genetic/epigenetic analyzed to determine the incidence, the mechanisms, and the potential biological significance of its Inactivation. As methylation detection method of p16 gene, the methylation specific PCR(MSP) is sensitive and specific for methylation of any block of CpG sites in a CpG islands using bisulfite-modified DNA. The genomic DNA is modified by treatment with sodium bisulfate, which converts all unmethylated cytosines to uracil(thymidine). The primers designed for MSP were chosen for regions containing frequent cytosines (to distinguish unmodified from modified DNA), and CpG pairs near the 5' end of the primers (to provide maximal discrimination in the PCR between methylated and unmethylated DNA). The two strands of DNA are no longer complementary after bisulfite treatment, primers can be designed for either modified strand. In this study, 13 paraffin embedded block tissues were used, so the fragment of DNA to be amplified was intentionally small, to allow the assessment of methylation pattern in a limited region and to facilitate the application of this technique to samlples. In this 13 primary HNSCC tissues, there was no methylation of p16 promoter gene (detected by MSP and automatic sequencing). The p16 protein-specific immunohistochemical staining was performed on 13 paraffin embedded primary HNSCC tissue samples. Twelve cases among the 13 showed altered expression of p16 proteins (negative expression). In this study, The author suggested that low expression of p16 protein may play an important role in human HNSCC, and this study suggested that many kinds of genetic mechanisms including DNA methylation may play the role in carcinogenesis.

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Maroon Clownfish, Premnas biaculeatus의 산란습성과 난 발생 및 자치어의 외부형태발달 (Spawning Behavior, Egg and Larvae Developments of Maroon Clownfish, Premnas biaculeatus)

  • 김종수;최영웅;노섬;윤영석;정민민;송영보;이치훈;이영돈
    • 한국양식학회지
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    • 제20권2호
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    • pp.96-105
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    • 2007
  • 해수관상어의 한 종인 maroon clownfish, Premnas biaculeatus의 안정적인 종묘생산기술개발의 일환으로 자연산란 후 난 발생과 초기생활사를 구명하였다. 짝짓기 및 산란 후 수컷과 암컷은 가슴지느러미와 입을 이용하여 알 관리를 하였으며, 주로 수컷이 하였다. 수정란은 진홍색을 띤 분리 침성부착란으로, 장경 1.95-2.01 mm ($1.99{\pm}0.03\;mm$), 단경 0.83-0.91 mm ($0.88{\pm}0.03\;mm$)의 타원형이었다. 수온 $27.0{\pm}0.5^{\circ}C$ 조건하에서 수정 1시간 10분경과 후에 최초 난할이 시작되어 2세포기가 되었다. 수정 후 23시간 40분에는 배체가 형성되었고, 부화는 120-150시간 사이에 이루어졌다. 부화 직후의 자어는 전장 3.10-3.44 mm (평균 $3.22{\pm}0.07\;mm$)로 타원형의 적갈색 난황(평균 장경 $0.58{\pm}0.08\;mm$, 평균 단경 $0.46{\pm}0.04\;mm$)을 복부 전반부에 가지고 있었으며, 근절 수는 9+17=26개이고 입과 항문은 열려있었다. 부화 후 10일째 치어는 전장 5.64-6.89 mm (평균 $6.21{\pm}0.69\;mm$)로 성장하였고, 등지느러미 28개, 뒷지느러미 17개, 꼬리지느러미에 28개의 기조수를 보였다. 부화 후 19일째 치어의 전장은 8.32-10.98 mm (평균 $9.34{\pm}1.11\;mm$)이었고, 3개의 백색 가로띠가 주황색 몸체에 생기기 시작했다.

일부 만 30세 이상 성인에서 구강건조증 관련요인 분석 (The Associated Factors with Xerostomia in Adults Aged 30 Years and Over)

  • 한해성;권다애;김리나;김유나;이결희;이나람;이다정;이승희;최준선
    • 치위생과학회지
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    • 제13권1호
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    • pp.62-70
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    • 2013
  • 본 연구는 구강건조증 인식도와 관련요인을 분석하여 구강건조증 예방 및 환자관리법에 대한 기초자료를 제공하기 위하여 실시하였다. 2012년 8월 1일부터 9월 30일까지 인천 및 경기지역에 거주하는 만 30세 이상 성인 240명을 대상으로 설문조사를 시행하였으며, t검정과 일원배치분산분석 및 다중선형회귀분석을 시행한 결과 다음과 같은 결론을 얻었다. 1. 일반적 특성과 구강건조증 인식도의 관련성을 분석한 결과 51세 이상이고 직업이 없으며, 월 평균 수입이 300만원 미만이라고 응답한 집단에서 구강건조증을 더 많이 인식하였다(p<0.05). 2. 건강상태와 구강건조증 인식도의 관련성을 분석한 결과 전반적으로 구강건강이 좋지 않으며, 치아우식증과 치주질환 및 구내점막질환 증상이 2개 이상인 집단에서 구강건조증을 더 많이 인식하였다. 또한 전반적으로 전신건강이 좋지 않으며, 만성질환에 이환되고 매일 약물을 복용하는 집단, 수면상태에 만족하지 않고 절망감을 인식한 집단에서 구강건조증을 더 많이 인식하였다(p<0.05). 3. 삶의 질과 구강건조증 인식도와의 관련성을 분석한 결과 저작능력, 대화능력 및 일상활동에 문제가 있고, 통증 불편함이 있으며 불안 우울한 집단에서 구강건조증을 더 많이 인식하였다(p<0.001). 4. 전신건조감과 구강건조증 인식도와의 관련성을 분석한 결과 피부와 눈, 입술 및 비강 내 점막이 자주 건조한 집단에서 구강건조증을 더 많이 인식하였다(p<0.001). 5. 구강건조증 인식도와 연관성의 강도를 분석한 결과 구강건조증 인식도는 삶의 질($\beta$=0.436)과 가장 연관성이 높았 다. 다음은 매일 복용 약물 수($\beta$=0.239), 전신건조감($\beta$=0.200), 절망감 인식($\beta$=0.160), 구내점막질환 증상 수($\beta$=0.099)의 순으로 나타났다(p<0.05). 이상의 연구결과로 볼 때 구강건조증은 삶의 질 저하를 초래할 수 있으므로 사회적 관심이 필요하며, 특히 구강보건인력은 구강건조증의 원인이나 부작용 및 치료법 등에 대한 관심도를 더욱 높여야 할 것이다. 또한 계속구강건강관리체계의 운영을 통해 구강건조증 예방 및 완화법에 대한 교육을 더욱 강화하여야 하고, 구강건조증에 대한 환자의 느낌이나 타액분비저하로 인해 나타나는 구강 내 변화에 세심한 관심과 철저한 모니터링이 수반되어야 할 것이다.

가정간호 시범사업 간호진단 및 간호중재 분석 연구 (A Study Analyzing Nursing Diagnoses and Nursing Interventions used in a Demonstration Home Care Project)

  • 서미혜;이혜원;전춘영
    • 대한간호
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    • 제34권5호
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    • pp.52-67
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    • 1996
  • As home care in developing and becoming part of the health care delivery system in Korea, it is necessary to examine the use of nursing diagnoses and related nursing interventions with a view to increasing the standardization of nursing recording. This study was done to examine the nursing diagnosis and related nursing interventions used in home care. Data were collected using a chart review of the nursing notes written for the home care given to 38 patients who had pulmonary diseases or traumatic brain or spinal cord injuries and who had received home care as part of a demonstration home care project in a college of Nursing in Seoul. Early on in the project discussions as to format and use to nursing diagnosis was done and a tool was developed based on Gordon's eleven functional catergories with the addition of categories to cover family and environment. This tool was used in the data collection. Data included nursing diagnosis, etiologies and interventions. Real numbers and percentages were used in the analysis. The results show that the most frequently used diagnoses were in the category of physical function (75.6%), followed by the category of emotional and social function (21.8%). The least frequently used category was the one for family and environment (2.6%). The order of the frequency of recorded nursing interventions was the same, 82.3% for physical function, 16.2% of emotional and social function and 1.5% for family and environment. Under the category of physical functioning the most frequently used nursing diagnoses were related to mobility (62.2%), nutrition (23.6%) and elimination (11.9%). The frequencies of nursing interventions for these three diagnostic categories were 69.8%, 16.0% and 10.8% respectively. For emotional and social functioning, the most frequently used diagnoses were for cognition-perception (37.1%), self-perception (30.6%) and perception of health (23.7%). The ordering of the frequency of nursing interventions varied slightly. The most frequently used interventions were for the category of self-perception (31.7%) followed by cognition-perception (24.1%) and perception of health (22.9%). Looking at individual diagnoses, it was found that within the categroy of physical functioning, the most frequently used diagnosis was "impaired physical mobility" (29.5%) and this diagnosis involved 43.9% of the interventions. This was followed by "ineffective breathing pattern" (19.4%) with 17.7% of interventions, and "alteration in nutrition, less than body requirements" (11.2%) with 8.1% of the interventions. For the emotional social category, noncompliance was the most frequently used nursing diagnosis (18.2%) with 19.2% of the interventions. This was followed by "anxiety" (13.4%) with 13.6% of the interventions and by "knowledge deficit" (13.4%) but with only 5.5% of the interventions. The other diagnoses and interventions did not follow this pattern of frequency. Although there were a large number of diagnostic and intervention events, the number of actual diagnoses and interventions used were relatively small ranging from six interventions for "knowledge deficit" to 40 interventions for "imparied physical mobility". From this it can be concluded that the results of this study could be used as basic data for the development of standardized charts with respect to nursing diagnosis and interventions for clients with pulmonary disease and clients with traumatic brain or spinal cord injuries. Interventions that were direct care activities (1178) were much more frequent that education (430), and assessment and observation (148). There were also few diagnoses or interventions related to the family and the environment. This suggests two areas that need to be developed in home care and that need to be considered in the development of standardized records for use in home care.

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감마선 조사에 의한 뇌조직의 Jun 및 p53유전자 발현 (Expression of Jun and p53 Genes from the Brain of Rats Irradiated with $^{60}Co{\gamma}$-ray)

  • 김용석;우종규;이용성;고재경;전하정;이명자
    • Radiation Oncology Journal
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    • 제14권4호
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    • pp.265-279
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    • 1996
  • 방사선은 DNA손상을 초래하고 세포 성장에 관련된 유전자의 발현 조절 및 apoptosis등을 유발한다고 알려져 있으며 본 연구는 신경계에 있어 방사선 조사 후 종양 발생율과 시간 경과의 관계 및 조사 양과 암 발생의 관계를 구명하기 위해 코발트 60의 전신조사에 따른 흰쥐 뇌 조직의 생체 반응을 연구하고자 하였다. 이를 위하여 상기조직의 jun 및 p53 유전자의 발현도를 1 Gy로 부터 100 Gy 범위의 감마선 용량별 및 1시간에서 6시간까지의 조사 훈 경과 시간 별로 Northern 분석하였다. Jun유전자 발현도는 ley이하에서 1시간 이내에 한계수준에 도달하였으며 30 Gy의 조사 1시간 째에 최대였다. 또한 조사 1시간 이후 1 Gy로부터 10 Gy 범위에서는 조사 5시간 및 6시간까지 점진적으로 증가되었으나 20 Gy로부터 100 Gy 범위에서는 조사 2시간까지 증가 후 감소되는 양상을 나타냈다. p53유전자의 발현도는 1 Gy이하에서 1시간 이내에 한계 수준에 근접했고 1 Gy의 조사 후 6시간 째에 최대였다. 1 Gy로부터 40 Gy까지의 범위에서는 조사 5시간 및 6시간까지 점진적으로 증가되는 반면 50 Gy에서 100 Gy범위에서는 조사 2시간 째까지 증가 후 감소되는 양상을 보였다. 따라서 감마선 조사양이 높을수록 jun 및 p53유전자는 신속하게 최대로 발현되었고 감마선 조사양이 낮을수록 서서히 증가되었다 그러나 jun유전자와 p53유전자의 감마선 조사에 따른 발현 양상에는 상호간의 연관성을 찾을 수 없었다.

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Yohimbine과 Atipamezole이 Xylazine-Ketamine 병용 마취견의 뇌파에 미치는 영향 (Effects of Yohimbine and Atipamezole in Dogs Anesthetized with Xylazine-Ketamine Combination on EEG)

  • 장환수;장광호;이만기;장인호
    • 한국임상수의학회지
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    • 제19권2호
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    • pp.174-185
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    • 2002
  • We investigated the effects of yohimbine and atipamezole in dogs anesthetized with xylazine-ketamine combination on electroencephalography (EEG) . Experiment groups were divided into three according to antagonists . Saline (1 ml) was used as an antagonist in group C, yohimbine (0.1 mg/kg) in group Y and atipamezole (50 ug/kg) in group A. Each group consisted of 5 dogs. Glycopyrrolate was injected 15 minutes prior to xylazine injection. Xylazine (1.1 mg/kg, IM) and ketamime (10 mg/kg, IV) were injected with the interval of 10 minutes. After 15 minutes, antagonists were administered intravenously. For EEG measurements, a recording electrode was positioned at Cz, which was applied to International 10-20 system. Heart rates, body temperature, respiratory rates, arterial blood pressure, $PaO_2$$PaCO_2$$PaCO_2$ at S4 in group Y was significantly decreased(p<0.05). Changes of electrolytes were not significant, except value of $Cl^-$ at S3 in group A. Mean head-up time (the time dogs showing head-up movement after antagonist injection, minutes) was $38.23^{\circ}$ae6.46 in group C, 2.54 $\pm$ 0.93 in group Y and 2.12$\pm$ 1.32 in group A. Mean sternal recumbent time (the time dogs showing sternal recumbency after antagonist injection, minutes) was 45.93$\pm$ 10.27 in group C, 11.91 $\pm$ 7.19 in group Y and 9.88$\pm$ 3.38 in group A. Mean walking time (minutes) was 53.49$\pm$ 9.21 in group C, 22.10$\pm$ 11.10 in group Y and 18.48$\pm$ 4.39 in group A. In group Y all dogs showed excitation and muscle rigidity in emergence. In group A, two dogs were also showed excitation and muscle rigidity, but were weaker than those of group Y.

친전자성 치환반응을 위한 $[^{18}F]F_2$ Gas의 생산 연구 (Production of $[^{18}F]F_2$ Gas for Electrophilic Substitution Reaction)

  • 문병석;김재홍;이교철;안광일;천기정;전권수
    • Nuclear Medicine and Molecular Imaging
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    • 제40권4호
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    • pp.228-232
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    • 2006
  • 목적 : $[^{18}F]F_2\;(T_{1/2}=110\;min)$ 기체를 이용하여 친전자성 치환반응으로 방사성동위원소 $^{18}F$을 표지하는 방법은 새로운 앙전자방출단층촬영용 방사성의약품 개발 분야에서 유용하게 이용되고 있다. 그림에도 불구하고 $[^{18}F]F_2$를 높은 생산수율과 비방사능으로 생산하기 위한 표적 개발 연구는 아직도 진행 중에 있다. 본 연구에서는 친핵성 치환반응으로 $^{18}F$을 도입하기 어려운 방사성의약품에 친전자성 치환반응으로 방사성동위원소를 도입할 수 있는 $[^{18}F]F_2$ 가스의 효율적인 생산에 관해 연구하였다. 대상 및 방법: 표적은 원추형 모양의 알루미늄 재질로 제작하였다. $[^{18}F]F_2$ 생산을 위한 핵반응으로 $^{18}O(p,n)^{18}F$를 사용하였으며, two-step 빔 조사방법을 이용하였다. 첫 번째 조사는 농축 $[^{18}O]O_2$가스를 표적에 충진한 후 빔 조사하여 $^{18}O(p,n)^{18}F$ 핵반응을 일으킴으로써 $^{18}F$를 생산한다. 생산된 $^{18}F$은 표적 챔버 기벽에 흡착된다. $[^{18}O]O_2$은 재사용을 위하여 냉각포획법으로 회수하였으며, $^{18}F$를 회수하기 위해 $[^{19}F]F_2/Ar$ 가스를 충진한 후, 두 번째 빔을 조사하여 방사성불소를 회수하는 방법으로 구성된다. 본 연구에서는 최적의 방사성불소 생산 조건을 찾기 위해 빔 조사 시간, 빔 전류 세기 농축 $[^{18}O]O_2$ 충진 압력 등의 변화에 따라 생산량을 평가하였다. 결과: 빔 조사 시간, 빔 전류, 농축 $[^{18}O]O_2$ 충진 압력 등의 조건을 변화시키면서 생산량을 평가한 결과 최적의 빔 조사 조건은 다음과 같다. 첫 번째 조사: 농축 $[^{18}O]O_2$을 약 15.0 bar충진, 13.2 MeV, 30 ${\mu}A$로 60-90분 조사; 두 번째 조사: 1% $[^{19}F]F_2/Ar$혼합가스 12.0 bar 충진, 13.2 MeV, 30 ${\mu}A$로 20-30분 조사 후 아르곤 가스로 회수하였을 때 EOB(end of bombardment) 기준으로 약 $34{\pm}6.0$ GBq(n>10)의 $[^{18}F]F_2$를 얻었다. 결론: $^{18}O(p,n)^{18}F$ 핵반응을 이용하여 친전자성 방사성동위원소 $[^{18}F]F_2$를 생산하였다. 표적 챔버는 알루미늄으로 제작하였으며 본 연구에서 연구된 $[^{18}F]F_2$가스는 친핵성 치환반응으로 방사성동위원소를 도입하기 어려운 다양한 방사성의 약품개발에 유용하게 이용될 수 있을 것이다.

건강한 중년 남성에서 커피 음용 습관이 혈중 총 콜레스테롤 값에 미치는 영향 (The Effect of Coffee Consumption on Serum Total Cholesterol Level in Healthy Middle-Aged Men)

  • 신명희;김동현;배종면;이형기;이무송;노준양;안윤옥
    • Journal of Preventive Medicine and Public Health
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    • 제27권2호
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    • pp.200-216
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    • 1994
  • In present study, the authors investigated the possible effect of coffee consumption on serum cholesterol level in 1017 men between the ages of 40 and 59 years, who were randomly selected from the members of Seoul Cohort Study. Serum total cholesterol data was collected with other serologic indices (e.g. systolic blood pressure, diastolic blood pressure, hight, weight, etc.) through the program of biennial health check-up offered by Korean Medical Insurance Corporation (KMIC). The amount of coffee consumption was assessed by a self-administered questionnaire through mailing. Other confounding factors, such as age, body mass index, cigarette smoking, alcohol consumption, physical activity, and other dietary intake pattern were also determined by the questionnaire. The differences in means of serum total cholesterol in compared to non consumers were $-0.4{\pm}3.56mg/dl$ for those drinking less than 1 cup a day, $-0.6{\pm}3.60mg/dl$ for those drinking 1 cup a day, and $7.1{\pm}3.41mg/dl$ for those drinking more than 2 cups a day. Since smoking interacted the relationship between coffee consumption and serum total choleaterol, we re-analyzed those relationship in smokers and non-smokers separately Other atherogenic behaviors were well correlated with total cholesterol, so we adjusted the mean values of serum total cholesterol through multivariate model selection with age(r=0.12), total cigarette index (cigarette-years; r=0.10), Quetelet's index ($Kg/m^2$, r=0.16), daily calory expenditure (kcal/day, r=0.06), weekly meat and poultry consumption(g/week, r=0.05), weekly fish consumption (g/week, r=0.08), other caffeinated beverage intake (cups/week), and the amount of sugar and prim added to the coffee. Among those variables only age, Quetelet's index, fish consumption, and total cigarette index (in smokers) were remained in the models. After adjustment, the corresponing differences of total cholesterol in smokers were changed to $0.4{\pm}5.24mg/dl,\;-0.5{\pm}4.97mg/dl,\;and\;8.9{\pm}4.78mg/dl$, which were significantly different among themselves (P=0.011). In non-smokers, however, the differences were not statistically significant (P=0.76). Adjusted mean values of systolic blood pressure and diastolic blood pressure were also determined to evaluate the direct effect of coffee to cardiovascular system, but their means were not significantly different by coffee consumption(p=0.18 for SBP, p=0.48 for DBP). Asuming instant coffee in the most popular type of coffee in Korea, the association observed in our study between coffee and serum total cholesterol, especially in smokers, is very interesting finding for the connection between coffee and serum total cholesterol, because only 'boiled coffee' tend to show significant lipid raising effect rather than to other types of coffee, like filtered or espresso, in most of the western countries. We concluded that people who drink coffee more than 2 cups a day have significantly higher serum total cholesterol level than those who never drink coffee, especially in smokers.

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쌀의 품질평가 현황과 금후 연구방향 (Trend and Further Research of Rice Quality Evaluation)

  • 손종록;김재현;이정일;윤영환;김제규;황흥구;문헌팔
    • 한국작물학회지
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    • 제47권
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    • pp.33-54
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    • 2002
  • Rice quality is much dependent on the pre-and post harvest management. There are many parameters which influence rice or cooked rice qualitys such as cultivars, climate, soil, harvest time, drying, milling, storage, safety, nutritive value, taste, marketing, eating, cooking conditions, and each nations' food culture. Thus, vice evaluation might not be carried out by only some parameters. Physicochemical evaluation of rice deals with amy-lose content, gelatinizing property, and its relation with taste. The amylose content of good vice in Korea is defined at 17 to 20%. Other parameters considered are as follows; ratio of protein body-1 per total protein amount in relation to taste, and oleic/linoleic acid ratio in relation to storage safety. The rice higher Mg/K ratio is considered as high quality. The optimum value is over 1.5 to 1.6. It was reported that the contents of oligosaccharide, glutamic acid or its derivatives and its proportionalities have high corelation with the taste of rice. Major aromatic compounds in rice have been known as hexanal, acetone, pentanal, butanal, octanal, and heptanal. Recently, it was found that muco-polysaccharides are solubilized during cooking. Cooked rice surface is coated by the muco-polysaccharide. The muco-polysaccharide aye contributing to the consistency and collecting free amino acids and vitamins. Thus, these parameters might be regarded as important items for quality and taste evaluation of rice. Ingredients of rice related with the taste are not confined to the total rice grain. In the internal kernel, starch is main component but nitrogen and mineral compounds are localized at the external kernel. The ingredients related with taste are contained in 91 to 86% part of the outside kernel. For safety that is considered an important evaluation item of rice quality, each residual tolerance limit for agricultural chemicals must be adopted in our country. During drying, rice quality can decline by the reasons of high drying temperature, overdrying, and rapid drying. These result in cracked grain or decolored kernel. Intrinsic enzymes react partially during the rice storage. Because of these enzymes, starch, lipid, or protein can be slowly degraded, resulting in the decline of appearance quality, occurrence of aging aroma, and increased hardness of cooked rice. Milling conditions concerned with quality are paddy quality, milling method, and milling machines. To produce high quality rice, head rice must contain over three fourths of the normal rice kernels, and broken, damaged, colored, and immature kernels must be eliminated. In addition to milling equipment, color sorter and length grader must be installed for the production of such rice. Head rice was examined using the 45 brand rices circulating in Korea, Japan, America, Australia, and China. It was found that the head rice rate of brand rice in our country was approximately 57.4% and 80-86% in foreign countries. In order to develop a rice quality evaluation system, evaluation of technics must be further developed : more detailed measure of qualities, search for taste-related components, creation and grade classification of quality evaluation factors at each management stage of treatment after harvest, evaluation of rice as food material as well as for rice cooking, and method development for simple evaluation and establishment of equation for palatability. On policy concerns, the following must be conducted : development of price discrimination in conformity to rice cultivar and grade under the basis of quality evaluation method, fixation of head rice branding, and introduction of low temperature circulation.

홀스타인 거세우에 대한 육성기 농후사료 급여형태 및 출하월령이 성장발육, 사료이용성 및 도체특성에 미치는 효과 (Effects of Feeding Type of Concentrates During Growing Period and Slaughter Age on Growth Performance, Feed Efficiency and Carcass Characteristics in Growing-Fattening Holstein Steers)

  • 강수원;정하연;안병석;오영균;손용석
    • Journal of Animal Science and Technology
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    • 제46권6호
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    • pp.989-998
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    • 2004
  • Holstein 거세우 48두를 대상으로 육성기 농후사료 급여수준 및 출하월령에 따른 산육능력 및 도체특성 구명을 위해 6개 처리(T1 : 자유채식 19개월령 출하, T2 : 제한급여 19개월령 출하, T3 : 자유채식 22개월령 출하, T4 : 제한급여 22개월령 출하, T5 : 자유채식 25개월령 출하, T6 : 제한급여 25개월령 출하)를 두어 4개월령부터 25개월령까지 사양시험 후 도체조사를 실시한 결과, 육성기 농후사료 자유채식 및 제한급여에 따른 출하월령별 체중 및 전기간의 일당증체량은 19, 22 및 25개월령에 각각 657.7${\sim}$731.3kg과 1.090${\sim}$1.245kg, 749.0${\sim}$776.5kg과 1.079${\sim}$1.130kg, 그리고 772.4${\sim}$811.9kg과 0.975${\sim}$1.030kg으로, 출하체중은 자유채식보다 제한급여가 그리고 출하월령이 높을수록 높았고, 일당증체량도 자유채식보다 제한급여가 그리고 출하월령이 낮을수록 높았으며, 제한급여가 자유채식보다 약 8.3% 증가하였고 출하월령이 경과됨에 따라 월평균 2.0%씩 감소하였다. 1kg 증체에 소요된 TDN은 평균 6.765kg 이었고, 제한급여가 자유채식보다 8.4% 적게 소요되었고, 출하시기가 1개월 늦어짐에 따라 소요량이 약 4%가 증가되었다. 도체조사 결과, 등지방두께 및 등심단면적은 4.6${\sim}$8.5mm(평균 6.7mm) 및 73.8${\sim}$81.8cm2(평균 77.1cm2)로 자유채식보다 제한급여가 그리고 출하시기가 늦어질수록 두껍거나 넓어졌고, 근내지방도는 1.17${\sim}$3.67(평균 2.46)로 자유채식보다 제한급여가 그리고 출하시기가 늦어질수록 높았다. 경제성 분석결과 총 소득은 537.2${\sim}$1,071.8천원/두으로 자유채식보다 제한급여가 그리고 출하월령이 늦어질수록 높았지만, 월평균 소득은 26.4${\sim}$52.9천원/두으로 T4>T6>T2의 순으로 높았다. 이상과 같은 결과들을 종합해 볼 때, Holstein 거세우 비육시 조사료원이 볏짚일 경우, 육성기에는 농후사료를 체중의 1.9% 수준으로 그리고 비육기에는 자유채식의 형태로 하되, 22${\sim}$25개월령 사이에 출하하는 것이 바람직 할 것으로 판단된다.