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Relaxation of Roll-off Characteristics in Organic Electrophosphorescence Diodes

  • Son, Kyung-Soo;Yahiro, Masayuki;Imai, Toshiro;Yoshizaki, Hiroki;Adachi, Chihaya
    • 한국정보디스플레이학회:학술대회논문집
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    • 2007.08b
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    • pp.1474-1477
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    • 2007
  • We demonstrate relaxation of roll-off characteristics by controlling the dopant concentrations and the thickness of an emitter layer in electrophosphorescence diodes composed of 2,6-dicarbazolo-1,5-pyridine (PYD2)-host doped with 25 wt%-Iridium(III)bis[(4,6-di-fluorophenyl)-pyridinato-$N,C^2$] picolinate (FIrpic).

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Acharacteristics on the forming of fishing ground and population ecological study of Yellow tail, Seriola quinqueradiata, in the coastal waters off Gim-nyeong of Jeju Island, Korea (제주도 김녕 연안해역의 방어 어장형성 특성과 자원생물학적 기초 연구)

  • Chang, Dae-Soo;Yoo, Joon-Taek;Kim, Byung-Yeob;Lee, Seung-Jong;Kwon, Dae-Hyeon;Koo, Jun-Ho;Ahn, Gem-Ma;Oh, Im-Yeol
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.46 no.4
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    • pp.406-415
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    • 2010
  • The forming of fishing ground and the population ecological characteristics of yellowtail, Seriola quinqueradiata, in the coastal waters off Gim-nyeong of Jeju Island were investigated. The stock of yellowtail, Seriola quinqueradiata, between Jeju Island and coastal areas of the East Sea is probably the same. Water temperature probably is a major factor for controlling distribution of yellowtails in deeper, offshore areas off Jeju Island. However, the major factor that determines aggregation of yellowtails in coastal areas of Jeju Island, especially off Gim-nyeong is probably strong tidal currents driven by distribution of yellowtails rather than hydrological conditions such as Yellowtails collected off Jeju Island were from 1 to 4yrs old and about 50% of them were $1^{-yr}$ old, probably indicating overfishing. Jack mackerel was the major prey item for yellowtails off Gim-nyeong from October to March, suggesting concurrence of the two species.

The Influence of Non-Linear Frequency Compression on the Perception of Speech and Music in Patients with High Frequency Hearing Loss

  • Ahn, Jungmin;Choi, Ji Eun;Kang, Ju Yong;Choi, Ik Joon;Lee, Myung-Chul;Lee, Byeong-Cheol;Hong, Sung Hwa;Moon, Il Joon
    • Korean Journal of Audiology
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    • v.25 no.2
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    • pp.80-88
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    • 2021
  • Background and Objectives: Non-linear frequency compression (NLFC) technology compresses and shifts higher frequencies into a lower frequency area that has better residual hearing. Because consonants are uttered in the high-frequency area, NLFC could provide better speech understanding. The aim of this study was to investigate the clinical effectiveness of NLFC technology on the perception of speech and music in patients with high-frequency hearing loss. Subjects and Methods: Twelve participants with high-frequency hearing loss were tested in a counter-balanced order, and had two weeks of daily experience with NLFC set on/off prior to testing. Performance was repeatedly evaluated with consonant tests in quiet and noise environments, speech perception in noise, music perception and acceptableness of sound quality rating tasks. Additionally, two questionnaires (the Abbreviated Profile of Hearing Aid Benefit and the Korean version of the International Outcome Inventory-Hearing Aids) were administered. Results: Consonant and speech perception improved with hearing aids (NLFC on/off conditions), but there was no significant difference between NLFC on and off states. Music perception performances revealed no notable difference among unaided and NLFC on and off states. The benefits and satisfaction ratings between NLFC on and off conditions were also not significantly different, based on questionnaires, however great individual variability preferences were noted. Conclusions: Speech perception as well as music perception both in quiet and noise environments was similar between NLFC on and off states, indicating that real world benefits from NLFC technology may be limited in Korean adult hearing aid users.

The Influence of Non-Linear Frequency Compression on the Perception of Speech and Music in Patients with High Frequency Hearing Loss

  • Ahn, Jungmin;Choi, Ji Eun;Kang, Ju Yong;Choi, Ik Joon;Lee, Myung-Chul;Lee, Byeong-Cheol;Hong, Sung Hwa;Moon, Il Joon
    • Journal of Audiology & Otology
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    • v.25 no.2
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    • pp.80-88
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    • 2021
  • Background and Objectives: Non-linear frequency compression (NLFC) technology compresses and shifts higher frequencies into a lower frequency area that has better residual hearing. Because consonants are uttered in the high-frequency area, NLFC could provide better speech understanding. The aim of this study was to investigate the clinical effectiveness of NLFC technology on the perception of speech and music in patients with high-frequency hearing loss. Subjects and Methods: Twelve participants with high-frequency hearing loss were tested in a counter-balanced order, and had two weeks of daily experience with NLFC set on/off prior to testing. Performance was repeatedly evaluated with consonant tests in quiet and noise environments, speech perception in noise, music perception and acceptableness of sound quality rating tasks. Additionally, two questionnaires (the Abbreviated Profile of Hearing Aid Benefit and the Korean version of the International Outcome Inventory-Hearing Aids) were administered. Results: Consonant and speech perception improved with hearing aids (NLFC on/off conditions), but there was no significant difference between NLFC on and off states. Music perception performances revealed no notable difference among unaided and NLFC on and off states. The benefits and satisfaction ratings between NLFC on and off conditions were also not significantly different, based on questionnaires, however great individual variability preferences were noted. Conclusions: Speech perception as well as music perception both in quiet and noise environments was similar between NLFC on and off states, indicating that real world benefits from NLFC technology may be limited in Korean adult hearing aid users.

Early and Midterm Outcome of Redo Coronary Artery Bypass Grafting: On-Pump versus Off-Pump Bypass

  • Shin, Yu Rim;Lee, Sak;Joo, Hyun Chel;Youn, Young-Nam;Kim, Jong Gun;Yoo, Kyung-Jong
    • Journal of Chest Surgery
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    • v.47 no.3
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    • pp.225-232
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    • 2014
  • Background: Redo coronary artery bypass grafting (CABG) is still associated with increased morbidity and mortality as compared to the first-time operation. Further, the application of the off-pump technique to redo CABG is limited due to technical difficulties. The aim of this retrospective study was to analyze early and midterm results after redo CABG and compare the outcome of redo on-pump and off-pump CABG. Methods: From June 1996 to October 2011, elective redo CABG was performed in 32 patients. Mean age was 64.8 years (on pump 64.3 years vs. off pump 65.5 years; p=0.658), and 21 patients were male. Among these patients, 14 (43.8%) underwent on-pump CABG, and 18 (56.2%) underwent off-pump CABG. Results: Internal thoracic artery was used in 22 patients (68.8%), and total arterial revascularization was achieved in 17 patients (53.1%). The average number of distal anastomoses was 2.13, and the rate of incomplete revascularization was 43.8%. The rate of total arterial revascularization was higher in the off-pump group (14.3% vs. 83.3%, p<0.001), and the use of saphenous vein graft was more in the on-pump group (78.6% vs. 16.7%, p<0.001). Overall hospital mortality was 3.1% (n=1) and was comparable in both groups (on pump 7.1% vs. off pump 0%; p=0.249). Postoperative complications occurred in 9 patients (64.2%), and the rate of complications was high in the on-pump group without statistical significance (64.2% vs. 33.3%, p=0.082). The mean follow-up duration was 5.4 years, and overall survival at 10 years was $86.0%{\pm}10.5%$. There was no significant difference in the 10-year survival rate between the two groups (79.6% vs. 100%, p=0.225). Conclusion: Redo CABG can be safely performed with acceptable mortality. Redo off-pump coronary artery bypass is feasible with low mortality and morbidity, comparable target vessel bypass grafting, and long-term survival. The off-pump technique might be considered a safe option for redo CABG in high-risk patients.

SSR (Simple Sector Remapper) the fault tolerant FTL algorithm for NAND flash memory

  • Lee, Gui-Young;Kim, Bumsoo;Kim, Shin-han;Byungsoo Jung
    • Proceedings of the IEEK Conference
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    • 2002.07b
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    • pp.932-935
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    • 2002
  • In this paper, we introduce new FTL(Flash Translation Layer) driver algorithm that tolerate the power off errors. FTL driver is the software that provide the block device interface to the upper layer software such as file systems or application programs that using the flash memory as a block device interfaced storage. Usually, the flash memory is used as the storage devices of the mobile system due to its low power consumption and small form factor. In mobile system, the state of the power supplement is not stable, because it using the small sized battery that has limited capacity. So, a sudden power off failure can be occurred when we read or write the data on the flash memory. During the write operation, power off failure may introduce the incomplete write operation. Incomplete write operation denotes the inconsistency of the data in flash memory. To provide the stable storage facility with flash memory in mobile system, FTL should provide the fault tolerance against the power off failure. SSR (Simple Sector Remapper) is a fault tolerant FTL driver that provides block device interface and also provides tolerance against power off errors.

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Effects of the Sheath on Determination of the Plasma Density of Microwave Probe

  • Kim, Dae-Woong;You, Shin-Jae;Na, Byung-Keun;You, Kwang-Ho;Kim, Jung-Hyung;Chang, Hong-Young
    • Proceedings of the Korean Vacuum Society Conference
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    • 2012.02a
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    • pp.181-181
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    • 2012
  • The microwave probe for measuring plasma density is widely used for its advantages: First, it is not affected by the reactive gas. Second, it can measure local plasma parameters such as plasma density, plasma potential and plasma temperature. Third, it is simple and robust. A cut-off probe is the one of the most promising microwave probe. Recently, Kim et al. reveals the physics of the cut-off probe but the effect of the sheath on the determination of the plasma density is not explained. In this presentation, for taking account of sheath effects on determination of plasma density from the cut-off peak, a simplified circuit modeling and an E/M simulation are conducted. The results show that occupation ratio of sheath volume between two tips of the cut-off probe and subsequence pressure condition mainly change position of the cut-off peak with respect to plasma frequency. Magnitude of relative voltage taken on the impedance of sheath and the impedance of bulk plasma can explain this effect. Furthermore, effects of gap size, tip radius, and tip length ware revealed based on above analysis.

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Brain-Derived Neurotrophic Factor(BDNF) Genetic Polymorphism and the Long-term Outcome of Antidepressant Treatment in Korean Depressive Patients (한국인 우울 장애 환자에서 Brain-Derived Neurotrophic Factor(BDNF)의 유전자 다형성과 항우울제의 장기 치료 반응)

  • Koo, Jae-Woo;Lee, Hwa-Young;Paik, Jong-Woo;Kang, Rhee-Hun;Lee, Min-Soo
    • Korean Journal of Biological Psychiatry
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    • v.13 no.3
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    • pp.162-169
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    • 2006
  • Objective : Since some studies have shown that the brain-derived neurotrophic factor(BDNF) has an important role in the pathophysiology of depression, this study investigated the relationship between BDNF genetic polymorphism and the long-term outcome of the antidepressant treatment. Method : One hundred and eight patients with major depressive disorder were evaluated for the long-term outcome(up to 3 years) of antidepressant treatment. The severity and improvement of depression were assessed with the Clinical Global Impression(CGI) Scale. The genotypes of BDNF 196A/G polymorphism in the patients were determined using Restriction Fragment Length Polymorphism(RFLP). Result : The genotypes of 128 patients were investigated and 95 patients of those have been evaluated for 3 years. No significant differences were noted comparing three-genotype groups for CGI scales at baseline, 4 weeks, 8 weeks, 1 year, 2 years and 3 years. Conclusion : This result shows that BDNF polymorphism investigated in this study was not associated with the long-term outcome of the antidepressant treatment. However, further studies with another BDNF polymorphism should be needed.

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Measuring and Reducing Off-Target Activities of Programmable Nucleases Including CRISPR-Cas9

  • Koo, Taeyoung;Lee, Jungjoon;Kim, Jin-Soo
    • Molecules and Cells
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    • v.38 no.6
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    • pp.475-481
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    • 2015
  • Programmable nucleases, which include zinc-finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), and RNA-guided engineered nucleases (RGENs) repurposed from the type II clustered, regularly interspaced short palindromic repeats (CRISPR)-CRISPR-associated protein 9 (Cas9) system are now widely used for genome editing in higher eukaryotic cells and whole organisms, revolutionising almost every discipline in biological research, medicine, and biotechnology. All of these nucleases, however, induce off-target mutations at sites homologous in sequence with on-target sites, limiting their utility in many applications including gene or cell therapy. In this review, we compare methods for detecting nuclease off-target mutations. We also review methods for profiling genome-wide off-target effects and discuss how to reduce or avoid off-target mutations.