• Title/Summary/Keyword: Ocular development

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Development of Videooculograph for Vestibular Function Test (전정 기능 평가를 위한 영상 안구 운동 측정 시스템의 개발)

  • 김수찬;남기창;이원선;김덕원
    • Journal of the Institute of Electronics Engineers of Korea SC
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    • v.40 no.3
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    • pp.189-198
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    • 2003
  • Videooculography (VOG) is one of the eye-movement measurement methods used for objective evaluation of vestibule -ocular reflex. A key feature of VOG is to estimate accurately the center of pupil and ocular torsion with being less influenced by the upper eyelid droop, eyelashes, corneal reflection, and eye blinks. Especially, it Is important to find the accurate center of the pupil in 3-D VOG because the inaccurate pupil center causes significant errors on measuring torsional eye movement. A new algorithm was proposed to find the center of pupil which is a little influenced by factors mentioned above. In this study, real time three-dimensional VOG which can measure horizontal, vortical, torsional eye movements, and the diameter of pupil was implemented using the proposed method.

A neonate with Joubert syndrome presenting with symptoms of Horner syndrome

  • Lee, Narae;Nam, Sang-Ook;Kim, Young Mi;Lee, Yun-Jin
    • Clinical and Experimental Pediatrics
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    • v.59 no.sup1
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    • pp.32-36
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    • 2016
  • Joubert syndrome (JS) is characterized by the "molar tooth sign" (MTS) with cerebellar vermis agenesis, episodic hyperpnea, abnormal eye movements, and hypotonia. Ocular and oculomotor abnormalities have been observed; however, Horner syndrome (HS) has not been documented in children with JS. We present the case of a 2-month-old boy having ocular abnormalities with bilateral nystagmus, left-dominant bilateral ptosis, and unilateral miosis and enophthalmos of the left eye, which were compatible with HS. Brain magnetic resonance imaging (MRI) revealed the presence of the MTS. Neck MRI showed no definite lesion or mass around the cervical sympathetic chain. His global development was delayed. He underwent ophthalmologic surgery, and showed some improvement in his ptosis. To the best of our knowledge, the association of HS with JS has not yet been described. We suggest that early neuroimaging should be considered for neonates or young infants with diverse eye abnormalities to evaluate the underlying etiology.

Development of a vestibulo-ocular reflex measurement system for the study of cybersickness (사이버멀미 경감 연구를 위한 전정안구반사 측정 시스템 개발)

  • Jeon, Hyeonjin;Chang, EunHee;Wendimagegn, Tariku Weldtsadik;Park, Chan Hyun;Jeong, Ji Woon;Kim, Hyun Taek
    • Science of Emotion and Sensibility
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    • v.18 no.1
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    • pp.27-38
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    • 2015
  • Vestibulo-ocular reflex (VOR) is a compensatory response of the extraocular muscles generated by vestibular signals to stabilize images on the retina during head/body movements. It has been reported that mismatches between retinal and vestibular information, which cause motion sickness or cybersickness, modify VOR. To investigate the characteristic changes of VOR in subjects experiencing cybersickness, we developed a low-cost, multi-purpose VOR measurement system using LabVIEW and Arduino. To test the applicability of the system, we performed two experiments. In Experiment 1, horizontal and vertical VORs of four participants were measured using a vestibular autorotation task. In Experiment 2, eight participants were exposed to a virtual navigation to measure changes of VORs as an index of cybersickness. We observed significantly greater head rotations and eye movements while the participants were exposed to the virtual navigation than to a static image. The results suggest that the present system can help understand the psychophysiological mechanisms of cybersickness symptoms.

Retinal Projection Display for Low Vision Aid

  • Nakamura, Hajime;Ando, Takahisa;Shimizu, Eiji
    • 한국정보디스플레이학회:학술대회논문집
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    • 2002.08a
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    • pp.1009-1011
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    • 2002
  • We developed a Retinal Projection Display for a low vision aid. This device can be applied to a low vision whose visual sense is weak. In the device, a digital image was formed with spatial light modulator(SLM) and projected onto a retina with the Maxwellian View. The image on this display can be seen clearly without our ocular accommodation and a low vision can see it without correction of a refraction error.

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EROGOTHIONEINE RESCUES PCl2 CELLS FROM BETA-AMYLOID-INDUCED APOPTOTIC DEATH

  • Jang, Jung-Hee;Surh, Young-Joon
    • Proceedings of the PSK Conference
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    • 2003.10b
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    • pp.141.2-142
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    • 2003
  • beta-Amyloid (A$\beta$) peptide is the major component of senile plaques and considered to have a causal role in the development and progression of Alzheimer's disease. There has been compelling evidence supporting that $A\beta$-induced cytotoxicity is mediated through oxidative and/or nitrosative stress. Recently, considerable attention has been focused on dietary manipulation of oxidative and/or nitrosative damage. L-Egrothioneine (EGT) is a low-molecular weight naturally occurring thiol compound of dietary origin which exists in milimolar concentrations in the brain, liver, kindney, erythrocytes, ocular tissues and in seminal fluids of mammals. (omitted)

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Application of Skin Color Analysis about Digital Color System for Oriental Medicine Observing a Person's Shape and Color Implementation (한방 찰색 구현을 위한 디지털 색체계의 피부색 분석에의 적용)

  • Lee, Se-Hwan;Cho, Dong-Uk;Kim, Bong-Hyun
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.33 no.2C
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    • pp.184-191
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    • 2008
  • Oriental base diagnosis method is not going to hospital different from Oriental medicine and because of the possible disease diagnosis through the network and many communication equipment. Especially diagnosis development using ocular inspection method aspect of Oriental medicine among an aging society advance into cut the medical cost for contribution. Ocular inspection method the most important look at disease color that is Observing a Person's Shape and Color which is implementation the development of methodology and important the build of application ability system. So in this paper study observing a person's shape and color implementation of ocular inspection. Specially body's the five viscera presentate the five colors disease color in face that is important the color coordinate system thesis so that proceed the experiment for the color coordinate system analysis. Finally five color extract need the observing a person's shape and color through experiment select the digital color system and so real skin color analysis and comparison about the experiment which suggest the something to color coordinate system the best case of digital color system for observing a person's shape and color implementation.

Sex Steroid Hormone and Ophthalmic Disease (성호르몬과 안질환)

  • Kim, Jin-Ju;Yu, Hyeong-Gon;Ku, Seung-Yup
    • Clinical and Experimental Reproductive Medicine
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    • v.37 no.2
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    • pp.89-98
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    • 2010
  • Sex and its tropic hormones influence the lacrimal system, corneal anatomy and disease, aqueous humor dynamics and glaucoma, crystalline lens and cataract, and retinal disease. Dry eye occurs especially frequently during pregnancy, oral contraceptive use, and after menopause, during which androgen levels decrease. Androgen control development, differentiation, and lipid production of sebaceous glands throughout the body, and androgen deficiency also leads to meibomian gland dysfunction and evaporative dry eye. On the other hand, estrogen causes a reduction in size, activity, and lipid production of sebaceous glands. Sex and its tropic hormones also influence the corneal anatomy and disease, and corneal thickening occurred on the second day of the menstrual cycle and around the time of ovulation and appeared to be related to estrogen levels. Fuchs' dystrophy is more commonly seen in postmenopausal women than men and may be linked to hormonal changes that occur with aging. In addition, overexpression of estrogen and progesterone receptors in the conjunctiva of vernal keratoconjunctivitis patients. Serum progesterone levels also may be associated with intraocular pressure especially in pregnant women, and for the women. For women with cataracts, hormone levels were typical of menopause, and there was a significant negative correlation between estradiol and follicular stimulating hormone levels. In addition, serum testosterone levels are associated with the development of diabetic retinopathy. Although the role of sex hormones on the eye is largely unknown, and the results should be interpreted with caution until replicated, the functions of sex hormones in ocular disease remains to be investigated, because they may be involved in structure and function of the ocular components, which are important in the pathogenesis of ocular disease.

Dermal and Ocular Irritation Studies of Honeybee (Apis mellifera L.) venom (봉독의 피부자극시험 및 안점막자극시험)

  • Han, Sang-Mi;Lee, Kwang-Gil;Yeo, Joo-Hong
    • Korean Journal of Pharmacognosy
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    • v.42 no.1
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    • pp.76-81
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    • 2011
  • The study of irritation and toxicity of honeybee(Apis mellifera. L) venom collected by a bee venom collector applied topically to the skin and mucous membrane were carried out to prove the safety of honeybee venom in clinical use. Animal for the research was the rabbit and the solution for the test was made from honeybee venom. Six animals were used for the skin test and nine animals were used for the eye mucous membrane test. In results, both tests proved that honeybee venom makes no irritable reaction on skin and eye mucous membrane of rabbit. We consider that this result is helpful for saying about the safety of honeybee venom in clinical use.

Hematological and microbial analysis on a Holstein heifer with infectious bovine keratoconjunctivitis

  • Ha, Seungmin;Hur, Taiyoung;Kang, Seogjin;Jung, Younghun;Son, Junkyu;Kim, Donghyeon;Lee, Jihwan;Sung, Hyunhoon;Cho, Eunseok;Kim, Sangbeom
    • Korean Journal of Veterinary Service
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    • v.43 no.4
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    • pp.245-250
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    • 2020
  • Infectious bovine keratoconjunctivitis (IBK) is the most common ocular disease in cattle, manifesting as corneal opacity, corneal ulcerations and potentially vision loss. The present report describes a 10-month-old Holstein Friesian heifer with IBK treated by systemic tulathromycin, and subconjunctival injection of penicillin and dexamethasone. We investigated changes in the hematological indices and microorganisms related to IBK after treatment. Neutrophils and monocytes decreased during recovery, so it was assumed that these two types of white cells are associated with IBK. Moraxella bovoculi was cleared in the eye, nasal cavity, and oral cavity after treatment. The distribution of M. bovoculi before treatment indicated that a combined systemic and subconjunctival treatment was necessary. The lesioned eye was found to be overwhelmed by Mycoplasma bovoculi, while pathogen abundance was reduced in the nasal cavity and oral cavities. These results suggest that antibiotic treatment can alter the composition and relative abundance of microorganisms.