• 제목/요약/키워드: Occupational Safety

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IN VITRO AND IN VIVO EVALUATION OF THE GENOTOXIC EFFECT OF 2-BROMOPROPANE BY THE ALKALINE SINGLE-CELL GEL ELECTROPHORESIS(COMET) ASSAY

  • Kim, Soo-Jin;Yu, Il-Je;Lee, Yong-Mook;Chung, Ho-Keun;Maeng, Seung-Hee
    • 한국독성학회:학술대회논문집
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    • 한국독성학회 2002년도 Molecular and Cellular Response to Toxic Substances
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    • pp.146-146
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    • 2002
  • The alkaline single cell gel electrophoresis (comet) assay was used to clarify in vitro and in vivo genotoxicity of 2-bromopropane (2-BP). For in vitro studies, fresh medium containing 2-BP (2.50, 1.00, 0.50, 0.25, 0.10, 0.05, 0.01 mM, and vehicle control) were added in human lymphocytes.(omitted)

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A Study on the Better Operation of Occupational Safety and Health Management Systems

  • Choi, Jae-Wook;Yoon, Seok-J.;Lee, Gwan-Hyung;Yang, H.S.
    • International Journal of Safety
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    • 제4권1호
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    • pp.32-37
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    • 2005
  • This study was conducted to identity the characteristics of occupational health and safety management systems around the world, to survey the implementation of OHSMS in Korean companies, to find problems and corrective measures, and to understand the opinions of top management about OHSMS. Questionnaires on the operation of occupational health and safety management systems in Korean manufacturing companies were carried out. Occupational health and safety management systems around the world, including OHSAS 18001, BS8800, KOSHA 18001, VPP, J-OHSMS, were reviewed. In order to implement an occupational health and safety management system successfully, it was found that the management should consider occupational health and safety as important, provide employees with necessary training, and have a strong commitment to occupational health and safety.

산업안전보건청의 설립 필요성과 추진방안에 관한 연구 (A Study on the Necessity and Action Plan of Establishment of Occupational Safety and Health Executive in Korea)

  • 정진우
    • 한국산업보건학회지
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    • 제27권1호
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    • pp.1-12
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    • 2017
  • Objectives: The major objectives of this study are to review the requirements for the advancement of occupational safety and health administrative organization and to propose measures to establish an Occupational Safety and Health Executive. Methods: The problems of occupational safety and health administrative organization in korea were examined empirically and cases of occupational safety and health administrative organizations in developed countries were investigated (United Kingdom, United States, Germany, and Japan). A plan for establishing an Occupational Safety and Health Executive was proposed over the short and medium term. Results: An occupational safety and health administration is characterized by a professional and technical nature, and even more so in modern society. Therefore the greatest value required by an occupational safety and health administrative organization is expertise. In addition, administrative values it requires include efficiency, specificity, independence, and activity. The Korean occupational safety and health administrative organization has a number of problems in terms of these values. The most appropriate way to realize these values is to establish an Occupational Safety and Health Executive. It is desirable to establish such an Occupational Safety and Health Executive in a phased manner taking into consideration its relationship with Korea Occupational Safety and Health Agency(KOSHA), including KOSHA's functional adjustment Conclusions: In order to solve the deep-seated problems in occupational safety and health administrative organization and to advance occupational safety and health administration in Korea, it is necessary to establish an Occupational Safety and Health Executive as a foundation for achieving an advanced industrial safety and health administration.

The Trend of Occupational Injuries in Korea from 2001 to 2010

  • Rhee, Kyung Yong;Choe, Seong Weon;Kim, Young Sun;Koo, Kwon Ho
    • Safety and Health at Work
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    • 제4권1호
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    • pp.63-70
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    • 2013
  • Objectives: This study is planned to assess the trend of occupational injuries in Korea from 2001 to 2010. Methods: Ten years of occupational injuries, from 2001 to 2010, were analyzed in order to investigate the changing profiles according to the various characteristics of injuries; economic sectors, age of the injured, and type of injuries. The changing profile of occupational injuries was investigated by comparison with an index-created relative value based on the number of cases of reference category. Results: The fatalities of construction, forest, agriculture, and service show the increasing trend. The nonfatal occupational injuries of the manufacturing sector were higher than those of other sectors in every year but the fatal occupational injuries of construction workers were higher than those of the manufacturing sector. Occupational injuries occurring due to amputation and those of slip and trip increased. The number of occupational injuries for the worker groups of 24 years old and below decreased and 45 years old and above increased. In comparison to the figure of fall from height, the figures of slip and trip or caught in equipment are higher in every calendar year. Conclusion: This study find out construction, forest, agriculture, and service sectors, aged worker with 45 years old and over can be target population for the strategies of occupational safety.

Occupational Health Could be the New Normal Challenge in the Trade and Health Cycle: Keywords Analysis Between 1990 and 2020

  • Kiran, Sibel
    • Safety and Health at Work
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    • 제12권2호
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    • pp.272-276
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    • 2021
  • This brief report aims to establish the keyword content of studies on occupational health and safety-the key framework of the world of work in the trade and health domain. Data were collected from the SCOPUS database, focusing on articles on occupational health and safety and related keywords, with an emphasis on abstracts and titles. Data were analyzed and summarized based on keywords included from the MeSH database. There were 24,499 manuscripts in the domain and 1,346 (5.40%) occupational health-related keywords, including those that overlapped. The most frequently referenced occupational health-related keyword was "occupational health" (452 articles), followed by "occupational safety" (141 articles). There were fewer keywords on occupational health in the trade and health literature. As the world of work has been prioritized because of the recent new normal of work life since the COVID-19 pandemic, examining the focus of occupational health priorities within the global perspective is crucial.

Subchronic Inhalation Toxicity Study of n-pentane in Rats

  • Kim, Jong-Kyu;Cho, Hae-Won;Han, Jeong-Hee;Lee, Sung-Bae;Chung, Yong-Hyun;Rim, Kyung-Taek;Yang, Jeong-Sun
    • Safety and Health at Work
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    • 제3권3호
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    • pp.224-234
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    • 2012
  • Objectives: This study was conducted in order to obtain information concerning the health hazards that may result from a 13 week inhalation exposure of n-pentane in Sprague-Dawley rats. Methods: This study was conducted in accordance with the Organization for Economic Co-operation and Development (OECD) guidelines for the testing of chemicals No. 413 'Subchronic inhalation toxicity: 90-day study (as revised in 2009)'. The rats were divided into 4 groups (10 male and 10 female rats in each group), and were exposed to 0, 340, 1,530, and 6,885 ppm n-pentane in each exposure chamber for 6 hour/day, 5 days/week, for 13 weeks. All of the rats were sacrificed at the end of the treatment period. During the test period, clinical signs, mortality, body weights, food consumption, ophthalmoscopy, locomotion activity, urinalysis, hematology, serum biochemistry, gross findings, organ weights, and histopathology were assessed. Results: During the period of testing, there were no treatment related effects on the clinical findings, body weight, food consumption, ophthalmoscopy, urinalysis, hematology, serum biochemistry, gross findings, relative organ weight, and histopathological findings. Conclusion: The no-observable-adverse-effect level (NOAEL) of n-pentane is evaluated as being more than 6,885 ppm (20.3 mg/L) in both male and female rats. n-pentane was not a classified specific target organ toxicity in the globally harmonized classification system (GHS).

A STUDY ON BIOLOGICAL MARKERS FOR THE ASSESSMENT OF GENOTOXICITY AND OXIDATIVE DAMAGE IN CHROMIUM EXPOSED WORKERS.

  • Maeng, Seung-Hee;Hiroshi Kasai;Yu, Il-Je;Lee, Byung-Moo;Lee, Jong-Yoon;Lee, Kwon-Seob;Chung, Ho-Keun;Chung, Hai-Won
    • 한국독성학회:학술대회논문집
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    • 한국독성학회 2001년도 International Symposium on Dietary and Medicinal Antimutgens and Anticarcinogens
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    • pp.121-122
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    • 2001
  • According to the epidemiological studies in chromium workers, hexavalent chromium is associated with the risk of lung cancer. Genotoxicity such as chromosome aberration, and cellular oxidative damages by reactive oxygen species produced by hexavalent chromium exposure may play an important role in the carcinogenesis process. We investigated the availabilities of several kinds of biological markers to assess the genotoxicity and oxidative damages from chromium exposure in Korean chromium plating workers.(omitted)

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