• Current Optics and Photonics
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• 제4권6호
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• pp.545-550
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• 2020

We propose a hole-filling method to solve discontinuous depth representation and to reduce the visible seams and cracks that cause the limitation of the viewing angle of the three-dimensional (3D) image in the multilayer type 3D display system. The occlusion and the disocclusion regions between layers, such as the visible seams and cracks, are a major bottleneck of the multilayer type 3D display system to represent a volumetric 3D image by stacking multiple images. As a result, in the reconstructed 3D image, the visible seams and cracks appear as brighter overlapping and undesirable cut-off. In order to resolve the problems above, we applied the depth-fused effect to the sub-depth map generating algorithm and improve the viewing characteristics of the multilayer type 3D display. The experimental demonstrations are also provided to verify the proposed scheme.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제28권4호
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• pp.356-364
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• 2006

Transverse mandibular deficiency has a many problem in growing patients. Therefore, Mandible symphysis widening is recommended. A new surgical technique has been developed to widen the mandible. The purpose of this study is to report the effect of mandibluar symphyseal distraction osteogenesis by use of bone-borne type distractor. The surgical procedure was accomplished under general anaesthesia with step-line osteotomy. Bone-borne type distractor was used to generally widen the mandible. The expansion achieved in the mandible was 8.31mm at the device, 6.32mm at the canines, 4.06mm at the first molars. The symphyseal distraction gaps were bridged by new bony regeneration. Mandibular symphseal distraction osteogenesis increased mandibular arch width, stabilized occlusion, and corrected dental crowding.

• 대한치과의사협회지
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• 제10권6호
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• pp.347-349
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• 1972

The authors selected fifty children aged 2 to 4 years who had normal occlusion from the patients admitted at the Pedodontic Department in the Infirmary of Dental College, S.N.U. Study casts were taken and observed on the primate spaces and terminal planes which are characteristics of primary dentition. The results were as follows: 1. The percentages of terminal planes were 56%±7.02 in mesial step type, 38.0%±6.86 in straight step type, 6.0%±3.36 in distal step type, respectively. 2. The percentages of primate space were 80%±5.09 in maxillary dental arch and 5.0%±7.06 in mandibular dental arch. 3. The percentage of mesial step type in korean children was higher in comparison with that in foreign children and the percentage of the primate space was about the same in korean & foreign children.

• 대한치과보철학회지
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• 제54권1호
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• pp.1-7
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• 2016

목적: 수직 교합 고경 증가 시 발생하는 하안모의 변화가 안모의 유형에 따라 어떤 차이가 있는 지 평가하여, 임상적으로 유의하여야 할 안모 유형을 알고자 한다. 대상 및 방법: 진단을 위해 측모두부규격방사선사진을 촬영한 환자 중 261명을 추출하여 그 대상으로 하였다. 시상적 안모 패턴은 Class I, II, III로 분류하였고, 수직적 안모 패턴은 hypodivergent, normodivergent, hyperdivergent로 나누어 환자를 9가지 집단으로 분류하였다. 각각의 환자를 가상적 시뮬레이션 프로그램을 이용하여 하악 중절치 기준 2 mm 수직 교합 고경을 증가시킨 후 연조직 Pogonion의 후방 이동량, 연조직 Menton의 하방 이동량을 측정한 후 연조직 Pogonion의 후방 이동량/연조직 Menton의 하방 이동량의 비율을 구하여 9가지 집단별로 어떤 차이가 있는 지 서로 비교하였다. 비교분석은 2-way ANOVA로 검정하고 사후 분석은 Tukey test를 이용하였다. 모든 검정은 유의수준 5%에서 수행되었다. 결과: 연조직 Pogonion의 후방 이동량은 Class I, II, III 간의 비교에서는 Class III 집단에서, hypodivergent, normodivergent, hyperdivergent 간의 비교에서는 모든 집단에서 통계적으로 유의한 차이를 보였다(P<.05). 연조직 Menton의 하방 이동량은 Class I, II, III 및 hypodivergent, normodivergent, hyperdivergent 집단에서 모두 통계적으로 유의한 차이를 보였다(P<.05). 연조직 Pogonion의 후방 이동량 대 연조직 Menton의 하방 이동량 비율은 Class I, II, III 및 hypodivergent, normodivergent, hyperdivergent 집단에서 모두 통계적으로 유의한 차이를 보였으며(P<.05) 9가지 집단 중 Class II & hyperdivergent 집단에서 가장 크게 나타났다. 결론: 수직 교합 고경의 증가 시 시상적 안모의 패턴 및 수직적 안모의 패턴에 따라 하안모의 변화는 유의한 차이가 있었으며, Class II & hyperdivergent 얼굴 패턴을 가진 환자는 수직 교합 고경 증가가 동반되는 치료 시 다른 유형에 비해 하안모의 변위량이 클 수 있다.

• 대한족부족관절학회지
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• 제17권1호
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• pp.52-59
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• 2013

Purpose: The purpose of this study is to evaluate treatment results of multidisciplinary approach of critical ischemic limb with diabetic foot. Materials and Methods: From March 2005 to March 2012, 674 diabetic foot patients were analyzed. Among them, 85 patients were neuroarthropathic type, 383 patients were infectious type, and 206 patients were ischemic type. The subjects were 206 patients who had critical ischemic limbs and major or minor amputations were done. Various single or combined treatment method before amputation was performed. We investigated their ABI, HbA1c, main occlusion lesion, limb salvage and hospitalization period by various treatment method. Results: Major amputation was 27 cases, minor amputation was 179 cases. Mean HbA1c was 8.2%, and mean ABI was 0.66. Main occlusion lesion was 6 cases at common iliac artery, 13 cases at external iliac artery, 9 cases at internal iliac artery, 11 cases at common femoral artery, 23 cases at deep femoral artery, 52 cases at superficial femoral artery, 35 cases at popliteal artery, 40 cases at posterior tibia artery, 35 cases at anterior tibial artery, 28 cases at peroneal artery, and 13 cases at dorsalis pedis artery. Major amputations were decreased, minor amputations were increased, and hospitalization period was reduced by treatment of multidisciplinary approach. Conclusion: Treatment of multidisciplinary approach, which include preoperation percutaneus transluminal angioplasty, vascular surgery, and amputation, of critical ischemic limb with diabetic foot had advantages of limb salvage and hospitalization period reduction.

• 한방재활의학과학회지
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• 제18권1호
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• pp.47-63
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• 2008

Objectives : Eucommiae cortex is reported that it helps bone and skeletal muscle stronger. In case of bone, many report is presented, but reports related to skeletal muscle are rarely existed. So in order to investigate effects of Eucommiae cortex on the skeletal muscle atrophy following stroke, cerebral infarct was induced by the middle cerebral artery occlusion (MCAO) in the rats. Methods : In order to induce MCAO rats, nylon suture was advanced and then blocked middle cerebral artery(MCA). Water extract of Eucommiae cortex was treated for 15 days, once a day orally, after the MCAO. Effects were evaluated with muscle weights, muscle fiber type composition, cross-sectioned area of muscle fibers in soleus and gastrocnemius of the unaffected and affected hind limbs. And MyoD protein expression in gastrocnemius was demonstrated with immunohistochemistry and western blotting. Results : In the affected hind limb of the MCAO rats, muscle weight loss of gastrocnemius and tibialis anterior muscles were attenuated by Eucommiae cortex treatment. In soleus muscle of the affected hind limb of the MCAO rats, increase of type-I fibers and decrease of type-II fibers were induced by Eucommiae cortex treatment. In soleus muscle of the affected hind limb of the MCAO rats, decrease of cross-sectioned areas of type-I fibers was attenuated by Eucommiae cortex treatment. In gastrocnemius muscle of the affected hind limb of the MCAO rats, increase of type-I fibers and decrease of type-II fibers were induced by Eucommiae cortex treatment. In gastrocnemius muscle of the affected hind limb of the MCAO rats, decreases of cross-sectioned areas of type-I and type-II fibers were attenuated by Eucommiae cortex treatment. In gastrocnemius muscle of the affected and unaffected hind limb of the MCAO rats, MyoD expressions were increased by Eucommiae cortex treatment. Conclusions : These results suggest that Eucommiae cortex has a protective effect against muscle atrophy, through the inhibition of the muscle cell apoptosis, following the central nervous system demage.

• 대한치과교정학회지
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• 제22권4호
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• pp.869-880
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• 1992

The purpose of this study was to evaluate the difference and relationship between the slope of articular eminence and the inclination of upper and lower incisor teeth, which are related to the functional stability of occlusion in mandibular protrusion, according to Ricketts' facial types, by the use of lateral cephalogram and SAM2 articulator in 68-adult normal occlusion without tooth missing, orthodontic treatment and occlusal equilibration. The results of this study were as follows : 1 . The angle of articular eminence slope to occlusal plane in brachyfacial type was steeper than that in dolichofacial type, but the angle of articular eminence slope to SN plane and FH plane was not different between facial types. 2. The upper incisor axis in dolichofacial type was steeper than that in brachyfacial type, but lingual surface slope of upper incisor was not different between facial types. 3. In all samples there was a positive correlation between the angle of articular eminence slope and the lingual surface slope of upper incisor to SN plane and FH plane, and in mesofacial type there was a positive correlation between the angle of articular eminence slope and the lingual surface slope of upper incisor to SN plane, FH plane and occlusal plane, and in brachyfacial type there was a positive correlation between the angle of articular eminence slope and the lingual surface slope of upper incisor to occlusal plane. 4. In all samples there was a positive correlation between the angle of articular eminence slope and the angle of Dc-Gn to SN plane, and in mesofacial type there was a positive correlation between the angle of articular eminence slope and the angle of Dc-Gn to occlusal plane, and in brachyfacial type there was a positive correlation between the angle of articular eminence slope and the angle of Dc-Gn to SN plane and FH plane. 5. In all samples there was a positive correlation between the angle of Dc-Gn and the lingual surface slope of upper incisor to SN plane and FH plane, and in mesofacial type there was a positive correlation between the angle of Dc-Gn and the lingual surface slope of upper incisor to SN plane. 6. In all samples and facial types there was a negative correlation between MP to 1 axis and condylar incisal angle.

• 한국산학기술학회논문지
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• 제20권11호
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• pp.305-313
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• 2019

최근 드론을 이용한 공간정보 구축이 활성화되면서 공간정보 산업발전에 많은 기여를 하고 있다. 하지만 드론 공간정보는 카메라의 중심투영에 의한 발생하는 폐색영역 뿐 아니라 가로수, 보행자, 현수막과 같은 적치물에 의한 폐색 영역이 필연적으로 발생한다. 이러한 폐색영역을 효율적으로 해결하기 위한 다양한 방안이 연구되고 있다. 본 연구에서는 폐색영역 해결을 위해 원초적인 재촬영이 아닌 딥러닝 알고리즘을 적용하기 위한 다양한 알고리즘별 조사 및 비교 연구를 수행하였다. 그 결과, 객체 검출 알고리즘인 HOG부터 기계학습 방법인 SVM, 딥러닝 방식인 DNN, CNN, RNN까지 다양한 모델들이 개발 및 적용되고 있으며, 이 중 영상의 분류, 검출에 가장 보편적이고 효율적인 알고리즘은 CNN 기법임을 확인하였다. 향후 AI 기반의 자동 객체 탐지와 분류는 공간정보 분야에서 각광받는 최신 과학기술이다. 이를 위해 다양한 알고리즘에 대한 검토와 적용은 중요하다. 따라서, 본 연구에서 제시하는 알고리즘별 적용 가능성은 자동으로 드론 영상의 폐색영역을 탐지하고 해결할 수 있어 공간정보 구축의 시간, 비용, 인력에 대한 효율성 향상에 기여할 것으로 판단된다.

• 한방안이비인후피부과학회지
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• 제32권3호
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• pp.77-86
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• 2019

Objectives : By analyzing symptoms of tinnitus, we tried to find out the relationship between deficiency and excess(虛實) and visceral pattern identification(臟腑辨證). By testing Tinnitus Handicap Inventory(THI), we evaluated the quality of life of people suffering from various aspects of tinnitus, as well as comparing treatment efficiency. Methods : 52 patients were recruited in this study who was ill with tinnitus. They wrote out the questionnaire about tinnitus and the THI. Results : The vast majority of high-grade tiny noise patients are deficiency type(虛症). The vast majority of low-grade roar patients are excess type(實症). Tinnitus persistence and feeling of ear occlusion were prominent in low-grade roar patients. low-grade roar patients suggest that overall quality of life is lower than high-grade tiny noise patients. In terms of treatment efficiency, spleen-stomach weakness(脾胃虛弱)-type, stomach heat(胃熱)-type and phlegm-fire(痰火)-type was higher than kidney essence depletion(腎精虧損)-type and liver qi depression(肝氣鬱結)-type regardless of the aspect of tinnitus. Conclusions : The present study suggests that tinnitus pattern may be helpful in differentiating patients with tinnitus, and the effectiveness of treatment can be predicted through differentiation.

• Bulletin of the Korean Chemical Society
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• 제31권9호
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• pp.2607-2612
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• 2010

Human tissue-type plasminogen activator (tPA) is a valuable thrombolytic agent used to successfully treat acute myocardial infarction, thromboembolic stroke, peripheral arterial occlusion, and venous thromboembolism. Recombinant tPA is accumulated as an inactive form in inclusion bodies of E. coli and is refolded in vitro, which is accompanied by extensive aggregation. In the present study, a tPA protease domain was expressed in an active soluble form in the cytosol of E. coli Rosetta-gami cells, which allowed disulfide bond formation and supplied the tRNA molecules required for six rarely used codons in E. coli. This strategy increased the amount of soluble protease domain protein and avoided the cumbersome refolding process. The purified protease domain not only degraded tPA substrate peptides but also formed a covalently bound complex with plasminogen activator inhibitor-1, as does full-length tPA. Soluble expression and purification of tPA domains may aid in functional analyses of this multi-domain protein, which has been implicated in many physiological and pathological processes.