• 제목/요약/키워드: Obstetrics and gynecology department

검색결과 2,181건 처리시간 0.033초

Anti-N-methyl-D-aspartate receptor encephalitis associated with ovarian teratoma in Korea: three case reports

  • Lee, Jisun;Kang, Seongwoo;Chang, Hye Jin;Lee, Yong Hee;Son, Joo-Hyuk;Kong, Tae Wook;Chang, Suk-Joon;Hwang, Kyung Joo;Kim, Miran
    • Journal of Yeungnam Medical Science
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    • 제38권4호
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    • pp.350-355
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    • 2021
  • Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a severe autoimmune paraneoplastic syndrome associated with ovarian teratomas. Most patients develop neurologic symptoms, including psychosis, memory deficits, seizures, or abnormal movements, and experience abdominal pain related to ovarian neoplasm. We present a case report of three patients diagnosed with anti-NMDAR encephalitis accompanied by ovarian teratomas at Ajou University Hospital in Korea. The patients demonstrated a different clinical course of the disease. However, upon diagnosis, all patients underwent surgical removal of the ovarian teratoma followed by intensive immunotherapy. The symptoms progressively improved following treatment. This is a case report of a rare autoimmune anti-NMDAR encephalitis associated with ovarian neoplasms, including immature teratoma.

Case-Control Study of Diet in Patients with Cervical Cancer or Precancerosis in Wufeng, a High Incidence Region in China

  • Jia, Yao;Hu, Ting;Hang, Chuan-Ying;Yang, Ru;Li, Xiong;Chen, Zhi-Lan;Mei, Ye-Dong;Zhang, Qing-Hua;Huang, Ke-Cheng;Xiang, Qun-Ying;Pan, Xiu-Yu;Yan, Yu-Ting;Wang, Xiao-Li;Wang, Shao-Shuai;Hang, Zhou;Tang, Fang-Xu;Liu, Dan;Zhou, Jin;Xi, Ling;Wang, Hui;Lu, Yun-Ping;Ma, Ding;Wang, Shi-Xuan;Li, Shuang
    • Asian Pacific Journal of Cancer Prevention
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    • 제13권10호
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    • pp.5299-5302
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    • 2012
  • Purpose: To investigate the diet of patients with cervical cancer and precancerosis in the Wufeng area, a high-incidence region in China. Methods: In the case group, 104 patients diagnosed with cervical cancer or cervical intraepithelial neoplasias (CINII/III) were recruited from the Wufeng area. Nine hundred thirty-six healthy women were selected from the same area as the matched controls. A questionnaire, which included questions about general lifestyle conditions, smoking and alcohol status, source of drinking water, green tea intake, and diet in the past year, was presented to all participants. Results: Green tea intake (P=0.022, OR=0.551, 95% CI=0.330-0.919) and vegetable intake (P=0.035, OR=0.896, 95% CI=0.809-0.993) were identified as protective factors against cervical cancer or CINII/III. There was no indication of any associations of other lifestyle factors (smoking status, alcohol status, source of drinking water) or diet (intake of fruit, meat/egg/milk, soybean food, onion/garlic, staple food and pickled food) with cervical cancer. Conclusions: The results suggest that eating more fresh vegetables and drinking more green tea may help to reduce the risk of cervical cancer or CINII/III in people of the Wufeng area.

Intravenous immunoglobulin G in women with reproductive failure: The Korean Society for Reproductive Immunology practice guidelines

  • Sung, Nayoung;Han, Ae Ra;Park, Chan Woo;Park, Dong Wook;Park, Joon Cheol;Kim, Na Young;Lim, Kyung Sil;Shin, Ji Eun;Joo, Chang Woo;Lee, Seung Eun;Kim, Jae Won;Lee, Sung Ki;IVIG Task Force Korean Society for Reproductive Immunology
    • Clinical and Experimental Reproductive Medicine
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    • 제44권1호
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    • pp.1-7
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    • 2017
  • The task force of the Korean Society for Reproductive Immunology recommends intravenous immunoglobulin G treatment in women with reproductive failure, including recurrent pregnancy loss and/or repeated implantation failure, who show cellular immune factors such as abnormal natural killer cell levels, natural killer cell cytotoxicity, and/or type 1 T helper immunity.

Bufalin, a Traditional Oriental Medicine, Induces Apoptosis in Human Cancer Cells

  • Takai, Noriyuki;Kira, Naoko;Ishii, Terukazu;Yoshida, Toshie;Nishida, Masakazu;Nishida, Yoshihiro;Nasu, Kaei;Narahara, Hisashi
    • Asian Pacific Journal of Cancer Prevention
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    • 제13권1호
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    • pp.399-402
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    • 2012
  • Bufalin is a traditional oriental medicines which induces apoptosis in some lines of human tumor cells. It constitutes the major digoxin-like immunoreactive component of Chan Su, obtained from the skin and parotid venom glands of toads. Bufalin is cardioactive C-24 steroids that exhibits a variety of biological activities, such as cardiotonic, anaesthetic, blood pressure stimulatory, respiratory and antineoplastic effects. In terms of its anti-tumor activity, bufalin has been demonstrated to inhibit the growth of tumors, such as endometrial and ovarian cancers. This commentary introduces biologic and therapeutic effects of bufalin in treating some cancers. The compound is able to mediate inhibition of cell growth, cell cycle arrest, apoptosis, and expression of genes related to the malignant phenotype in human cancer cells.