This study aimed to evaluate the safety and efficacy of various biodegradable mulching films in maize cultivation by analyzing crop growth, yield, film degradation rate, as well as soil chemistry, temperature, and moisture. The results indicated that maize plant height, heading, and silking rates were lower in plots without mulching than in those with biodegradable mulching (F, H, and V) and polyethylene (PE) films. Plant height, heading, and silking rates were consistent throughout the study period between PE and biodegradable mulching films. At harvest, there were no significant differences in the number of leaves per plant, shoot fresh weight, stem length, ear length, ear width, maize count, and yield per 10a between the PE and biodegradable mulching films. However, the light transmittance was higher with biodegradable than with PE films during cultivation and post-harvest. At 63 days post-transplanting, the H film showed the highest transmittance of up to 45% compared to the F and V films. Additionally, the films were completely degraded by 14 days post-harvest. The deterioration level (0-5) of biodegradable mulching films increased over time after transplanting, while the deterioration of the PE film was minimal. At 70 days post-transplanting, the deterioration level of biodegradable films ranged from 2.7 to 4.3, and from 3 to 5 post-harvest, with the H film exhibiting the highest degradation. Up to 49 days post-transplanting, the degradation rate of the biodegradable mulching films was comparable to that of the PE film. However, at 63 days post-transplanting, the degradation rate of the biodegradable film was significantly higher than that of the PE film. The H film, with a degradation rate of 56%, showed the highest rate, followed by the V film at 11%, and the F film at 8%. Although soil pH, electrical conductivity (EC), and organic matter content fluctuated throughout the observation period, there were no significant differences between soils covered with biodegradable mulching films and those covered with PE film. The soil temperature and moisture levels were also similar between the two film types. However, the use of mulch films increased soil temperature by approximately 2 ℃ and soil moisture by 5-15% compared to non-mulched soil. Thus, the biodegradable mulch films used in this study can be safely used without adversely affecting maize growth, yield, or the soil environment.