• Journal of Korean Medicine for Obesity Research
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• v.17 no.1
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• pp.54-60
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• 2017

Many obesity patients were affected by depressed liver function including hepatosteatosis. The aim of this study was to investigate the clinical effect of the obesity therapy with Korean herbal medicine (KHM) on obese patient with abnormal liver function. This is a retrospective observational study performed on obesity patients with abnormal liver function. All subjects have taken serum liver function tests (LFTs) before treatment. Ten patients showed abnormal LFTs. They were treated with KHM at least 15 days. During this treatment, LFTs were evaluated afterwards. Body weight and body mass index of the patients were decreased during treatments. Five of 10 subjects recovered normal levels of LFTs. While other subjects remained at abnormal level but their levels were decreased. This study shows that the obesity therapy including KHM could be effective to improve liver function on obese patient. Additional large scale studies are necessary for more evidences.

• Journal of Korean Public Health Nursing
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• v.27 no.3
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• pp.619-632
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• 2013

Purpose: The purpose of this study was to develop an obesity management program for obese children and examine its effects on body composition, self-efficacy, and health promotion. The obesity management program was based on a KAP & HBM mixed model and consisted of health education and group playing exercises. Method: This study was implemented at one elementary school in K city for a total of 12 weeks. The study subjects were a single group, and their body composition, self-efficacy, and health promotion were assessed at both pre-treatment and post-treatment. Data were analyzed by Wilcoxon Signed Rank Test using SPSS WIN 20.0. Result: After the program, the average height of subjects increased by 0.9cm (p=.001), whereas BMI decreased by $0.64kg/m^2$ (p=.003), obesity index decreased by 3.79% (p=.003), and body fat decreased by 1.34% (p=.002). There were significant effects on diet self-efficacy (p=.027), exercise self-efficacy (p<.001), and health promotion (p=.001). Conclusion: This obesity management program reduced the degree of obesity and improved self-efficacy and health promotion. Therefore, the obesity management program is an effective intervention method for elementary-aged obese children.

• Journal of Korean Medicine for Obesity Research
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• v.19 no.1
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• pp.31-41
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• 2019

Objectives: The purpose of this study was to investigate the effects of gender, age, body weight, muscle mass, fat mass, body mass index (BMI), metabolism, and compliance with medication on weight loss in obese adults. Methods: We reviewed the medical records of 178 patients who were visited to the Korean Oriental Clinic for 3~6 month and had obesity treatment using Gamitaeumjowee-tang from April 2017 to May 2017. We conducted a paired T-test, correlation coefficient and decision tree to analyze factors influencing obesity treatment. Results: The results of correlation analysis showed that initial weight (kg), initial fat mass (kg), BMI ($kg/m^2$), compliance with medication (%), Original Harris-Benedict Equation, Revised Harris-Benedict Equation and The Mifflin St Jeor Equation was significantly correlated to weight loss (kg) (P<0.001). As a result of constructing the decision tree model, it showed that over 5% weight loss of their initial weight (n=154) was related with initial BMI ($kg/m^2$), compliance with medication (%) and initial muscle mass (kg). In case of over 5 kg weight loss of their initial weight (n=131), it was related with initial BMI ($kg/m^2$), compliance with medication (%) and final BMI ($kg/m^2$). Conclusions: This study suggests that weight loss may be affected by initial factors and that initial factors can be used for obesity treatment.

• Journal of Korean Medicine for Obesity Research
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• v.22 no.1
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• pp.47-53
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• 2022

Objectives: The purpose of this study was to observe the effect of improving obesity after 4 week complex Korean medicine treatment in obese patients by retrospectively analyzing. Methods: A retrospective chart review was conducted on 44 patients who received obesity treatment at 23 Korean medicine clinics in Daejeon city. We analyzed weight, body mass index (BMI), body fat percentage, body fat mass, muscle mass, hip and waist circumference, EuroQol-5D (EQ-5D), Korean version of obesity-related quality of life scale (KOQOL), and satisfaction surveys at 4 and 8 weeks after treatment. Results: The weight, BMI change after 4 weeks and 8 weeks was decreased significantly. In addition, there were significant differences in fat mass, muscle mass, waist circumference, and hip circumference. Life quality scale EQ-5D and KOQOL showed decreased significantly. In the evaluation of overall satisfaction, safety, help level, recommendation intention, and revisit intention, more than 89% answered positively that they were satisfied. There were no serious side effects. Conclusions: It was significant effect on weight loss and obesity improvement after complex Korean medicine. And quality of life evaluation and satisfaction survey also show positive results.

• Journal of Korean Medicine for Obesity Research
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• v.3 no.1
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• pp.49-59
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• 2003

Objectives : The purpose of this study is to evaluate the effect the of treatment in obesity clinic in east-west collaboration center, furthermore to search for how to join and improve east medicine and west medicine more closely. Methods : 37 patients were classified into four groups by Body Mass Index(BMI); normal, overweight, 1st obesity and 2nd obesity groups. Weight, BMI, body fat rate and abdominal fat rate were compared in each group by paired t-test. Results & Conclusions : In distribution of sex, male were 10(27%), female were 27(73%). Mean age was $34{\pm}13$ and the patients in twenties un the most. Among four groups, the number of End obesity groups was the most. Most patients had a preference for western medication and ear acupuncture therapy. In general we could find the correlation between the effect of obesity treatment and the degree of obesity. The more the obesity degree was, the more weight loss was.

• Journal of Korean Medicine for Obesity Research
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• v.19 no.1
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• pp.68-78
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• 2019

Objectives: The purpose of this review is to analyse the trend in papers related to obese people with disabilities. Methods: We reviewed Korean Medicine papers by searching 4 Korean web databases and classified the papers by the year of publishment, the title of journals, the type of study, main treatment, assessment for outcomes. Results: There were 18 studies about the intellectually disabled, which accounted for most of the study. It is expected that intensive research on obesity for the intellectually disabled will be conducted in the future. Also, study on obesity for the disabled will require special attention. Disabled person tend to have a higher obesity rate and secondary diseases due to disabilities can be easily developed. Their health care capabilities are more likely lower than those of the general population. Given these considerations, it would be necessary to study metabolic syndrome in parallel in the study of obesity for the disabled. Disabled person are exposed to obesity more easily than ordinary people, and there is a higher risk of health degradation due to complications from obesity, which requires more attention and research. However, since there is not research in the oriental medical and medical circles on obesity in the disabled, medical approaches and studies on obesity in the disabled are necessary. Conclusions: We expect that more interest and research will be carried out on obesity for the disabled in the Korean medicine to achieve clinical application and to develop treatment protocols for the disabled obesity disease.

• Journal of Korean Medicine for Obesity Research
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• v.15 no.1
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• pp.33-37
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• 2015

Objectives: The purpose of this study is to report the effectiveness of Korean medicine treatment on 254 patients visited obesity clinic. Methods: Two hundred fifty-four patients, who had visited obesity clinic from May 2013 to November 2014, were analyzed by bioelectrical impedance analysis. We analyzed changes of weight, skeletal muscle mass, fat mass, body mass index (BMI) and body fat percentage after treatment, also investigated differences of weight and fat mass loss according to age, BMI and body fat percentage. Results and Conclusions: Male and female percent of the study group was 3.5% and 96.5%. All patients were constituted with 50.0% of 20~29-year-old group, 34.1% of 30~39-year-old and 15.9% of 40 and more year-old. In BMI, $21kg/m^2$, $21.0{\sim}22.9kg/m^2$, $23.0{\sim}29.9kg/m^2$, above $30kg/m^2$ were 20.5%, 30.3%, 42.1%, 7.1%, respectively. In Body fat percentage, under 25%, 25.0%~29.9%, 30.0%~34.9%, above 35% were 11.4%, 23.2%, 30.7%, 34.6%, respectively. 96.1% of patients were showed weight loss compared with baseline, the decrease of body weight was $2.96{\pm}1.86$ kg, that of BMI was $1.13{\pm}0.70kg/m^2$ and that of body fat percentage was $2.43%{\pm}2.06%$ after 1 month treatment. We observed a decline of weight and fat mass with higher BMI and body fat percentage at the baseline.

• Journal of Korean Medicine for Obesity Research
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• v.20 no.1
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• pp.31-39
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• 2020

Objectives: Obesity is becoming more popular disease worldwide. Because of the side effects of conventional obesity treatment modality, herbal medicine treatment is becoming more preferred. Gambihwan which including Ephedra sinica Staph is widely used in traditional Korean Medicine practice for obesity treatment. Garcinia cambogia is a kind of health functional food that has body fat reducing effect. Nowadays, ephedra and Garcinia cambogia are often used simultaneously in clinical practice of Korean Medicine. However, the effectiveness and safety of combination therapy in obesity treatment is not well established. Methods: We conducted retrospective observational study to explore effectiveness and safety of combination therapy. We evaluated effect of combined treatment of Gambihwan and Garcinia cambogia on body weight, body mass index, body fat mass, and waist hip ratio reduction. We also assessed safety via liver function test and adverse event. Results: Finally, 23 patients were included. In paired t-test, body weight significantly decreased from 64.50±14.50 kg to 62.94±13.85 kg (P<0.001) and body mass index were also significantly decreased from 24.43±3.79 kg/㎡ to 23.83±3.59 kg/㎡ (P<0.001). Body fat mass was also reduced. Aspartate transaminase and alanine aminotransferase were not significantly increased. There were no drug-induced liver injury and no severe adverse event. Conclusions: In our retrospective review, we found combination therapy of Gambihwan and Garcinia cambogia reduce body weight, body mass index and body fat mass. There were no severe adverse event and drug induced liver injury which indicated safety of combination therapy in obesity treatment.

• Clinical and Experimental Pediatrics
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• v.64 no.10
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• pp.511-518
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• 2021

The prevalence of childhood obesity is increasing worldwide at an alarming rate. While obesity is known to increase a variety of cardiovascular and metabolic diseases, it also acts as a risk factor for the development and progression of chronic kidney disease (CKD). During childhood and adolescence, severe obesity is associated with an increased prevalence and incidence of the early stages of kidney disease. Importantly, children born to obese mothers are also at increased risk of developing obesity and CKD later in life. The potential mechanisms underlying the association between obesity and CKD include hemodynamic factors, metabolic effects, and lipid nephrotoxicity. Weight reduction via increased physical activity, caloric restriction, treatment with angiotensin-converting enzyme inhibitors, and judicious bariatric surgery can be used to control obesity and obesity-related kidney disease. Preventive strategies to halt the obesity epidemic in the healthcare community are needed to reduce the widespread deleterious consequences of obesity including CKD development and progression.

• Journal of Yeungnam Medical Science
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• v.41 no.3
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• pp.158-165
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• 2024

Over the past few decades, there has been a notable increase in the incidence of pediatric obesity, which is a significant public health concern. Children who are obese have a greater risk of type 2 diabetes, hypertension, dyslipidemia, polycystic ovary syndrome, obstructive sleep apnea, and adult obesity. Lifestyle modification therapy is typically the initial approach to treat pediatric obesity. For patients who do not achieve success with lifestyle modification therapy alone, pharmacotherapy is the next logical treatment option. When selecting an anti-obesity medication (AOM), it is essential to first ascertain the medical background of the patient, including current medications and obesity-associated comorbidities. Evaluation of obesity phenotypes in patients may also be beneficial. AOMs for pediatric obesity include metformin, orlistat, glucagon-like peptide 1 agonists, phentermine, and the phentermine/topiramate combination. Sufficient lifestyle modification therapy should be administered before considering pharmacotherapy and continued after the initiation of AOM. To ensure healthy development, monitoring growth and puberty development during anti-obesity treatments is essential.