• Asian Pacific Journal of Cancer Prevention
• /
• 제15권23호
• /
• pp.10251-10254
• /
• 2015

Uterine cancer is the most common invasive gynaecological cancer in Australia. Early detection is a key predictive factor achieved by increasing public awareness and participation in screening. This observational study measures awareness of gynaecological malignancies, particularly uterine, among women in two rural areas of New South Wales, Australia. Patients presenting to gynaecology clinics in January to March 2014 were invited to complete a structured questionnaire. Women with a history of cancer and incomplete questionnaires were excluded. Of the 382 patients invited to participate, 329 (86%) responded with complete feedback. Most respondents were younger than than 50 years (66%) and married with at least 2 children (74%). The majority (94%) of participants had no awareness of uterine cancer and many (46%) were unable to identify common risk factors including obesity, diabetes and hypertension. The ability to identify risk factors was correlated to age, marital status and obesity. The study identifies poor awareness on uterine malignancies in two typical areas of rural Australia. Although external validity is limited by sociological factors, poor awareness of uterine cancer among rural patients in this study represents a valid public health concern. It is imperative to improve awareness of uterine cancer and available screening programs to facilitate early detection and cure.

• Journal of Nutrition and Health
• /
• 제49권4호
• /
• pp.223-232
• /
• 2016

Purpose: We investigated the potential interaction between the G-protein beta-3 subunit gene (GNB3) C825T polymorphism, a risk factor for chronic disease in various ethnicities, and obesogenic environments in overweight/obese Korean children. Methods: The present study was conducted as a cross-sectional study using measures of anthropometry, blood pressure (BP), and fasting blood samples as well as 3-day food records. Subjects were recruited from seven elementary schools in an urban district in Seoul, South Korea, between 2007 and 2008. A total of 1,260 children aged 8-9 years were recruited in the study, including 633 boys (50.3%) and 627 girls (49.7%). Results: The allele frequencies of the GNB3 polymorphism were C allele = 49.7% and T allele = 50.3% in subjects. In general, boys with T allele had higher BMI, systolic BP (SBP), and triglycerides, although their energy intake was not significantly different from boys with C allele. In contrast to boys, girls with T allele had lower BMI but higher SBP and energy intake than those with C allele. The girls with T allele had a significantly lower BMI and waist circumference in both the normal weight group and obese group (OB). T allele carriers in both genders had significantly higher TC than C allele carriers in the OB group. At last, girls with T allele in OB appeared to have significantly lower HOMA-IR than those with C allele. Conclusion: Unlike higher risk for negative health outcomes by the GNB3 polymorphism in various ethnicities, GNB3 polymorphism did not influence obesogenic environments in overweight/obese Korean children.

• 대한간호학회지
• /
• 제46권3호
• /
• pp.390-399
• /
• 2016

Purpose: The purpose of this study was to determine the effects of smartphone apps applying BodyThink program on BMI, percentage of body fat, skeletal muscle rate, body image, and self-esteem of adolescent girls. Methods: Sixty-eight high school girls with a BMI of over $25kg/m^2$ were recruited to participate in this study. Girls from four schools were divided into two groups: the experimental group, which used the smartphone apps applying BodyThink program, and the control group, which used smartphone apps and small group counseling. The experimental group received the BodyThink program 6 times, scheduled once a week, with each session lasting 40~50 minutes. Test measures were completed before and after the 6 week intervention period for all participants. Collected data was analyzed using Shapiro-Wilk test, descriptive statistics, ${\chi}^2$ test, independent t-test, Mann-Whitney U test with the SPSS/WIN 18.0 program. Results: The girls in the experimental group significantly improved their results in BMI(Z=-1.67, p=.042), percentage of body fat (Z=-3.01, p=.001), skeletal muscle rate (t=-3.50, p<.001), and self-esteem (t=2.66, p=.005) after the program, compared to the girls in the control group. Conclusion: Mobile applications applying psychological and emotional intervention programs have the potential to be effective alternative methods to improve the body composition and self-esteem of obese adolescent girls.

• 농업과학연구
• /
• 제48권3호
• /
• pp.557-565
• /
• 2021

Interest in research on various medicinal plants has increased globally over the last few decades, possibly due to their possible antibacterial and antioxidant activities. The present study was conducted to verify the antioxidant effects, antibacterial activity, and collagen synthesis and cell viability outcomes of adipocytes upon exposure to Abeliophyllum distichum Nakai (AdN). Antibacterial activity was measured through the Disc diffusion method to compare the growth ability of pathogenic microorganisms (E.coli, Salmonella). The absorbance was measured at 560 nm to calculate the active oxygen scavenging ability. Fibroblasts were dispensed in a 96-well plate at a density of 1 × 10⁵ cells·well^-1. The amount of procollagen was measured in each case using a procollagen type 1 C-peptide EIA KIT. The cytotoxicity of the Abeliophyllum distichum Nakai extract against animal adipocytes (Hanwoo backfat cells) was determined using a 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium (MTS) assay, a method that measures the conversion of MTS to Formazan by means of mitochondrial dehydrogenases. The concentrations of the samples were made to be 0.0125, 0025, 0.05, 0.1, and 0.5% and all were -completely absorbed into the disc in an incubator at 37℃ for 24 to 36 hours. For the 0.125 mg·disc^-1, effects of Abeliophyllum distichum Nakai on the antioxidant effect, antibacterial activity, and cell viability of adipocytes were found. However, Abeliophyllum distichum Nakai had no effect on collagen synthesis, thus suggesting that AdN extracts may be useful for the prevention and/or treatment of obesity.

• 한방비만학회지
• /
• 제23권1호
• /
• pp.28-41
• /
• 2023

Objectives: This study was aimed to evaluate the hemodynamic feasibility using pulse parameters as a way to establish safe dose guidelines for herbal prescription containing Ephedra herb (Ephedra intermedia Schrenk & C.A.Mey) on weight loss, and to provide a foundation for developing evidence-based guidelines for clinical use. Methods: Forty-two volunteers were recruited to participate in a study examining the changes in pulse wave characteristics following the ingestion of Gambi-hwan, a herbal prescription containing ephedra, over a period of 4 weeks, and pulse wave measurements were taken before and after the administration. Pulse wave parameters were measured in this study using a 3-dimensional radial pulse tonometry device (DMP-Lifeplus). In addition, questionnaire, blood pressure, temperature, and body composition were also measured as secondary measures. Results: Fifteen minutes after administration of Gambi-hwan, the non-adverse event group (non-AE) exhibited a statistically significant increase in several power and pressure-related parameters, including h1, h5, systolic area, pulse area, and pulse width, while the AE group showed a trend of decreasing stroke volume and increasing Radial Augmentation Index (RAI), w, and w/t. After 4 weeks of administration, both groups exhibited significant changes in pulse rate, w/t, RAI, t3/t, stroke volume (SV), and stroke volume Index (SVI). Notably, there are significant differences between AE group and non-AE group in w/t, SV, and SVI. Conclusions: These findings suggest that pulse parameters may be a useful way to establish safe dosing guidelines for weight loss herbal prescription containing ephedra. Further research is needed to confirm these results and to develop evidence-based guidelines for clinical use.

• 정신신체의학
• /
• 제22권2호
• /
• pp.112-120
• /
• 2014

연구목적 이 연구의 목적은 양극성 장애로 진단받은 정신과 외래 환자에서 야간 식이습관의 임상적 특성을 조사하는데 있다. 방 법 정신건강의학과 외래를 방문한 84명의 양극성 장애 환자를 대상으로 14개 항목의 야간 식이증후군 설문지(NEQ)를 자가 보고로 실시하였다. 이들의 인구학적, 임상적 특성을 조사하고 신체 질량 지수(BMI), 주관석 기분과 수면, 폭식과 체중에 관련된 삶의 질에 대한 평가를 Beck Depression Inventory(BDI), Binge Eating Scale(BES), Korean version of Obesity-related Quality of Life scale(KOQoL), Pittsburg Sleep Quality Index(PSQI) 등을 포함한 설문을 통해 얻었다. 결 과 양극성 장애 외래 환자 중 야간 식이증후군의 유병률은 14.3%(84명 중 12명)이었다. NES와 Non-NES군 사이에서는 경제적 상태와 동반되는 내과 질환을 제외한 성별, 나이, 교육 년 수, 결혼 및 직업 상태, 흡연, 음주 등의 인구사회학적 특성에서 양군간에 유의한 차이를 보이지는 않았다. 하지만, Non-NES 군에 비해 NES군에서 폭식이 많았고 비만으로 인한 삶의 질 저하가 나타났다. 결 론 이번 연구는 야간식이를 보이는 양극성 장애 외래환자의 임상적 특성을 처음으로 기술하였다. 비록 양극성 장애 외래 환자의NES군에서 뚜렷한 상관 관계를 보이는 특성이 많지는 않았지만, 상대적으로 NES 유병률이 높은 것으로 볼 때 임상에서 양극성 장애 환자 평가 시 비만 여부에 관계 없이 NES를 염두에 두어야 할 것이다.

• 정신신체의학
• /
• 제22권2호
• /
• pp.93-103
• /
• 2014

연구목적 본 연구의 목적은 조현병 외래 환자를 대상으로 야간식이증후군(night eating syndrome : NES)의 유병률과 이와 관련된 임상적 요인들에 대해 살펴보는 것이다. 방 법 정신건강의학과 외래를 방문한 201명의 조현병 환자들을 14 문항의 자기보고 형식인 야간식이증후군 설문지(Night Eating Questionnaire : NEQ)로 평가하였다. 인구학적, 임상적 특징과 체 질량 지수(BMI)을 조사하였고, 주관적인 기분과 수면, 폭식과 체중 관련 삶의 질에 대해서는 각각 Beck's Depression Inventory(BDI), Pittsburgh Sleep Quality Index(PSQI), Binge Eating Scale(BES)와 Korean version of Obesity-Related Quality of Life Scale(KOQoL)를 이용하여 평가하였다. 결 과 조현병 외래 환자에서 야간 식이 증후군의 유병률은 10.4%(201명 중 21명)이었다. NES 군과 non-NES 군간에 나이를 제외하면 인구사회학적 및 임상적 특성, BMI에서는 유의한 차이를 보이지 않았다. NES 군이 Non-NES 군에 비해 보다 우울했고, 수면과 폭식 양상, 체중 관련 삶의 질에 있어서 의미 있는 장애를 나타냈다. '아침 식욕부진'과 '지연된 아침식사'(NEQ에서 NES 핵심 항목 5개 중 2개)는 두 군간에 차이가 없었으나, '야간 섭식', '야간 식욕항진' 그리고 '기분/수면'은 NES 군에서 더 손상되어 있는 것으로 나타났다. 결 론 본 연구는 조현병 외래 환자를 대상으로 NES의 유병률과 관련 요인에 대해 기술한 최초의시도이다. 비록 NES와 비만과의 연관성은 밝히지 못했지만, 본 연구의 결과는 NES가 정신 건강에 부정적 영향을 준다는 사실을 보여주었다. 향후 이러한 결과를 뒷받침할 수 있는 추가 연구가 필요할 것이다.

• Journal of Preventive Medicine and Public Health
• /
• 제24권1호
• /
• pp.57-69
• /
• 1991

중심성 지방분포와 고혈압과의 관계와 비근 내측 피부두께가 기존의 말초성 지방분포를 나타내주는 삼두근 피부두께에 비해 더 우수한 지표가 되는지를 알아보기위해서 1990 년 해군수중 근무자 특수신체검사자 중에서 450 명을 연구자의 편의에 의해 추출되었다. 대상자의 평균 연령이 27.9 세였고 범위가 19-51세었다. 말초성 지방분포의 지표로 삼두근과 비골 내측 피부두께를, 중심성 지방분포는 견갑골하 피부두께와 이것과 삼두근으로 이루어진 비와 차이로 측정을 했다. 신체의 지방분포를 나타내는 피부두께와 이 들을 기준으로한 비와 차이의 지수를 4 분위수로 나누어 첫 1/4 분위수를 기준으로 하고 나머지 3 가지 수준을 기준에 비교를 했다. 연령과 전체적인 비만도를 다중지수분석으로 통제를 한 후 고혈압과의 관계에서 견갑골하 피부두께가 기준인 1/4 분위수와 비교해 보아 2/4, 3/4, 4/4 분위수로 증가함에 따라 각각 2.05(95 % 신뢰구간 1.18-3.59), 2.02(1.06-3.86), 4.00 (1.99-8.06) 의 유병비차비를 보였다. 견갑골하 피부두께와 비골 내측 피부두께의 차이 역시 4/4 분위수가 되었을 때만 2.45 (1.28-4.68)의 비차비를 보였다. 그 외의 삼근 피부두께와 비근내측 피부두께에서는 기준에 비교해 보아 1 을 포함하지 않은 비차비는 없었다. 연령과 전체적인 비만도를 조정한 비차비는 조정치 않은 조비차비에 비해 대체적으로 조금 감소했다. 비근 내측의 피부두께는 삼두근 피부두께에 비교해보아 더 우수한 말초성 지방분포를 대표해주는 피부두께로 보였다. 이러한 결과는 전체적인 비만도 수준과는 독립적으로 견갑골하 피부두께로 측정된 중심성 지방분포가 고협압과 관계가 있으며 우수한 중심성 지방분포를 나타내주는 지표가 됨을 시사해주는 소견이다.

• 척추신경추나의학회지
• /
• 제2권2호
• /
• pp.105-116
• /
• 2007

Objectives : Physical activity is known as beneficial to mental health like decreasing depression and stress. In this study, we tried to find out the relationship between body composition, stress, depression, and self-esteem with physical activity level. Methods : International Physical Activity Questionnaire(IPAQ)-short form, SRRS(Social readjustment rating scale), SRI(Stress response index), and BDI(Beck's depression index), SES(Self-esteem scale) were given to peri-menopausal women aged 45-55 and BMI$\geq$23kg/m2. They were given written consent and this study is performed under the permission of institutional review board of Kyung Hee East-west Neo Medical Center. Results : The mean of physical activity of total subjects was 2406MET-min/week(n=42). The physical activity of overweight(23kg/m2$\leq$BMI<25kg/m2) and obese(BMI$\geq$25kg/m2) permimenopausal women was 1428MET-min/week and 2970MET-min/week(p<0.05) respectively. When three levels of physical activity pattern(inactive, minimally active, and HEPA(Health-enhancing physical activity) active) was analyzed, all of them were heavily relied on the activity intensities of walking. The scores of BDI, SRRS, and SRI were lower and that of SES were higher in HEPA active group, not showing statical significance. Anger(subscale of SRI) measures were lower and SES measures were higher in HEPA active group than others among overweight women(p<0.05). Conclusions : The level of physical activity of peri-menopausal women was on the average, but the vigorous activity is thought to be necessary. The HEPA active group showed lower depression, stress and higher self-esteem than minimally active and inactive group.

• 대한통합의학회지
• /
• 제2권3호
• /
• pp.75-82
• /
• 2014

Purpose : The purpose of this study was to investigate the effect of pilates mat exercise (PME) and instability support surface exercise (ISSE) for TUG (Time up & go) and static balance in the elderly person aged 65 or more. Method : 30 subjects in Y-equestrian were randomly divided two group, pilates mat exercise (PME) group and instability support surface exercise (ISSE) group. Each group carried out 40 minutes exercise two times a week for 12 weeks. TUG (Time up & go) and Biorescue were measured for static balance. Result : The results were as follows, the TUG between pilates mat exercise (PME) group and instability support surface exercise (ISSE) group in post-test, were significantly different in measures (p<.05). And there were significant in two group after exercise (p<.05). The static balance between pilates mat exercise (PME) group and instability support surface exercise (ISSE) group in post-test, were significantly different in measures (p<.05). And there were significant in two group after exercise (p<.05). Conclusion : These finding revealed that pilates mat exercise was effective on TUG and static balance in the elderly person aged 65 or more so that these exercise can be new alterative exercise for obesity management in the elderly person.