• Journal of Korean Medicine for Obesity Research
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• v.8 no.1
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• pp.1-12
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• 2008

Adverse reactions to foods are common and increasing problems worldwide. It is important to differentiate between the different forms of adverse reactions to foods, in particular the difference between food intolerance and food allergy. Food allergy is an adverse immunologic response to food and typically rapid in onset, whereas food intolerance is consequence of a variety of non-immune mechanisms and slow in onset. It has been difficult to diagnose food intolerance because of lack of diagnosis measure. There are now effective findings to identify food intolerance, and paradigms with food allergy are shifting. Food intolerance affects virtually every part of the body-from mildly uncomfortable symptoms to severe illness. While there is no known simple 'cure' for food allergy and food intolerance, there are a number of measures that will help avoid and lessen symptoms and correct the underlying causes. We focus the diagnosis and treatment of food intolerance through various views.

• Journal of Lipid and Atherosclerosis
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• v.7 no.2
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• pp.88-97
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• 2018

The prevalence of atherothrombotic disease continues to rise, presenting an increasing number of challenges to modern society and creating interest in functional foods. Platelet activation, adhesion, and aggregation at vascular endothelial disruption sites are key events in atherothrombotic disease. Physiological challenges such as hyperlipidemia, obesity, and cigarette smoking are associated with vascular changes underlying platelet aggregation and inflammatory processes. However, it is difficult to determine the beneficial response of functional foods in healthy subjects. To address this problem, challenge models and high-risk models related to smokers, obesity, and dyslipidemia are proposed as sensitive measures to evaluate the effects of functional foods in healthy subjects. In this review, we construct a model to evaluate the effects of functional food such as natural products on blood flow based on a human intervention study.

• Clinical Psychopharmacology and Neuroscience
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• v.16 no.4
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• pp.481-488
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• 2018

Preliminary studies have claimed that short term fasting would negatively affect school performance and cognition. In contrast some other studies have reported not important decline in cognition and executive function as a result of fasting. Also limited attention was generally devoted to dietetic regimens, nutritional status and body weight. Yet neuroscience and neuro-cognitive aspects of acute hunger on the electroencephalogram and differences between obese and non-obese cases is not well understood. Hence, we decided to design and perform a case study in a more controlled situation similar to reality. Therefore, we performed several examinations including subjective tests (for eating status) and objective tests (cognitive tests such as Stroop effect and Sternberg search and electroencephalogram measures such as steady-state visual evoked potential and auditory steady-state responses) for an obese and a non-obese academic case before and after a simple breakfast. The results showed that the breakfast effects on the neuro-cognitive functions depend on either obesity status, nutritional status of the case or the type of cognitive task (visual or auditory). This paper would open a new insight to answer some important questions about the neuro-cognitive implications of fasting and feeding in obese and non-obese human cases.

• The Korean Journal of Food And Nutrition
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• v.34 no.1
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• pp.69-78
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• 2021

The aim of this study was to evaluate the basic data of Cirsium setidens Nakai fine powder (FPC), which will then be used in the development of functional fooditems. We measures and evaluated the level of pectolinarin content, phenol content, flavonoids content, antioxidants and anti-obesity properties of FPC. Our results from the study showed that the pectolinarin, phenol, and flavonoids contents of FPC measured at 10.95±0.1 5mg/g, 12.92±0.18 mg gallic acid equivalent (GAE)/g and 26.47±0.77 mg rutin equivalent (RE)/g, respectively. The exhibited antioxidant activity of FPC increased significantly depending on the dosage, and additionally. FPC did not show any cytotoxicity up to the dosage level of 500 μg/mL. During adipocyte differentiation, FPC significantly inhibited ROS production and lipid accumulation, compared with the control substance. These results suggest that FPC could be considered a promising resource of natural antioxidants and could serve a variety of health-improving roles in the production of functional food ingredients.

• Journal of Preventive Medicine and Public Health
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• v.46 no.6
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• pp.336-345
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• 2013

Objectives: Research has shown that obesity appears to spread through social ties. However, the association between other characteristics of social networks and obesity is unclear. This study aimed to identify the association between social network characteristics and body mass index (BMI, $kg/m^2$) in an elderly Korean population. Methods: This cross-sectional study analyzed data from 657 Koreans (273 men, 384 women) aged 60 years or older who participated in the Korean Social Life, Health, and Aging Project. Network size is a count of the number of friends. Density of communication network is the number of connections in the social network reported as a fraction of the total links possible in the personal (ego-centric) network. Average frequency of communication (or meeting) measures how often network members communicate (or meet) each other. The association of each social network measure with BMI was investigated by multiple linear regression analysis. Results: After adjusting for potential confounders, the men with lower density (<0.71) and higher network size (4-6) had the higher BMI (${\beta}$=1.089, p=0.037) compared to the men with higher density (>0.83) and lower size (1-2), but not in the women (p=0.393). The lowest tertile of communication frequency was associated with higher BMI in the women (${\beta}$=0.885, p=0.049), but not in the men (p=0.140). Conclusions: Our study suggests that social network structure (network size and density) and activation (communication frequency and meeting frequency) are associated with obesity among the elderly. There may also be gender differences in this association.

• Clinical and Experimental Pediatrics
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• v.53 no.10
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• pp.892-897
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• 2010

Purpose: This study evaluated the prevalence of the metabolic syndrome (MetS) and risk factors for metabolic derangement in young adults with childhood-onset hypopituitary growth hormone deficiency (ACOHGHD). Methods: Thirty patients with ACOHGHD who were treated with hormone-replacement therapy, aged 18 to 29 years, who visited the Seoul National University Children's Hospital between September 2009 and February 2010 were enrolled. Height, weight, waist circumference, hip circumference, and blood pressure were measured, and the clinical and hormonal features were reviewed retrospectively. We evaluated measures of metabolic derangement in the enrolled patients and in the data of healthy adults aged 20 to 29 years taken from the 2005 Korean National Health and Nutrition Examination Survey (KNHANES) as part of the National Cholesterol Education Program-the Adult Treatment Panel III. Results: Compared with the KNHANES participants, patients with ACOHGHD had significantly large waist circumference (men and women), high systolic blood pressure (BP) (women) and diastolic BP (men), and high serum triglyceride levels (women). The duration of illness correlated significantly with central obesity ($r^2$=0.546, $P$=0.003). The prevalence of MetS was 10% in patients with ACOHGHD and 2.3% in KNHANES participants. The prevalence of central obesity and MetS was higher in patients with ACOHGHD than in KNHANES participants ($P$<0.001 and $P$=0.042, respectively). Conclusion: Abdominal obesity correlated with the duration of illness in patients with ACOHGHD. Waist circumference should be measured in the clinic to prevent MetS, particularly in patients with a long history of ACOHGHD, regardless of age or sex.

• Journal of muscle and joint health
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• v.15 no.1
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• pp.62-72
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• 2008

Purpose: There has been a need to integrating the self-help program for arthritis with the Tai Chi for arthritis(SHTCA). The purpose of this study was to develop and to examine the effect of SHTCA for arthritis applying the nine movement Tai Chi. Method: This study was designed the pre-post test, quasi-experimental design. A total 47 participants were recruited in W-city in Korea, an experimental group(26) and a control group(21) at pre-test, but after the eight weeks the composition of the groups were changed to 22 experimental group and 15 control group. The experimental group participated in the SHTCA once a week for eight weeks. SHTCA program consisted of understanding of the arthritis, contracting of the promise, exercise for muscle strength and joint flexibility and the nine movements of Tai Chi exercise. The measures used to examine the effect of the SHTCA were shoulder flexibility, back flexibility, grasping power, balance, abdominal obesity rates, perception of health status, and EQ-5D standardized five dimensions, mobility, self-care, usual activities, pain/discomfort, and anxiety/depression. Results: At The completion of the eight weeks of SHTCA applying the nine movement Tai Chi, the experimental group reported a significance in a number of variables compared to those of the control group: the right shoulder flexibility(p=.018), left shoulder flexibility(p=.031), right grasping power(p=.014), left grasping power(p=.024), the perception of health status(p=.005) and abdominal obesity rates(p=.027). Conclusion: This SHTCA applying the nine movement Tai Chi would be helpful on right shoulder flexibility, left shoulder flexibility, right grasping power, left grasping power, abdominal obesity rates and the perception of health status for arthritis patients.

• The Journal of Pediatrics of Korean Medicine
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• v.38 no.1
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• pp.55-77
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• 2024

Objectives This study aimed to analyze the registration status and characteristics of clinical trials on herbal medicine (HM) and medication interventions for simple obesity in children and adolescents. Methods All interventional clinical trials registered in the International Clinical Trials Registry Platform of the World Health Organization until December 12, 2024, were collected. The study design, interventions, inclusion and exclusion criteria, and outcome measures were extracted. Results A total of 24 clinical trials (23 medications and 1 HM) were analyzed. The most common study designs were single-center, randomized controlled, parallel, and phase 2. Placebo controls were used in 87.5% of the studies, blinding was used in 79.1%, and quadruple blinding was the most common. Informed consent was obtained from 70.8% of the participants. Among the oral medications (66.6%), metformin was the most common (25%). Among the non-oral medications (29.1%), exenatide (Bydureon) was the most common intervention (42.8%). Body mass index was the most commonly reported primary outcome measure (79.1%), with most assessments performed at 6 months. Conclusions Based on the characteristics of the medication interventional clinical trial design analyzed in this study, additional high-quality multicenter traditional Korean medicine trials need to be designed in the future.

• Journal of the Korean Society of Clothing and Textiles
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• v.32 no.1
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• pp.134-146
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• 2008

This study measured the body parts of female adults in their 20s, 40s and 60s living in Japan and analyzed and examined the measures by age group in order to provide the basic data required for the somatics study of Koreans living abroad. The subjects were 304 women in their 20s, 40s and 60s born in Japan and living in Osaka at present, and 81 items were measured. The major results of this study are described below. All women in their 20s, 40s and 60s showed significant differences in weight, waist size and abdominal size. The 19 height items of which group were different from the measurements of the women in their 60s. All 20 length items displayed a significant difference by age group. The significant differences by age group were also observed in eight items of 12 width items, 10 items of 13 thickness items and 13 items of 14 girth items except the ankle girth. The weight measurements had a significant difference by age group(${\le}0.05$). The women in their 20s, 40s and 60s revealed almost similar values in the shoulder angles. As a result of the analysis above, the items that were considered being included in the obesity items in all age groups displayed significant personal differences. The women in their 20s had the largest sizes in the length and height items. The older the age, the higher the measures of width and girth items were. Those results helped to estimate the change of figures by torso by age.

• Journal of Fashion Business
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• v.14 no.1
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• pp.57-75
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• 2010

This study is done in Shanghai area by sample survey of female college students in their lower 20s. Through direct contact survey, this study collected and analyzed information on figure to understand feature of breasts and measurements of body to provide base information to improve product of brassiere for adult female in China. Data was analyzed by using SPSSWIN 13.0 Program and SAS 9.0. 1. From a result of factor analysis on 40 items of measures to derive the components of the shape of the breast, 6 factors were derived such as the factors to show the obesity of the bust, to show the ratio of the upper and lower area of the lower bust, droop and volume, to show the internal shape and broadness of the bust, to show the location and vertical size of the bust, to show the protrusion of the bust and the eternal shape of the bust. 2. From a result of classification on the shape of the breast of the Chinese women in their early 20s, 4 types were selected. Type 1 is the protrusion type that a woman has a broad drooped breast due to the development in the upper and lower parts of the chest as well as the highest height, a high degree of obesity in the bust part, big volume and much protrusion. Type 2 is the hemisphere type that the degree of obesity in the breast is second to Type 1 and a breast is located at a region higher than Type 1 as the degree of obesity in the breast is secondly highest, the lower part of the bust is bigger than the Type 1 and the degree of being broad and drooped is second to Type 1. Type 3 is the cone type with a breast of being drooped and broad a little bit and a certain degree of a volume. Type 4 is the flat type with the smallest value in the item that shows the obesity of the bust area and with the smallest value in the R$\ddot{o}$hrer index to have the small and slender body type for the bust area, which is somewhat flat due to a low slope at the internal side of the bust.