• Title/Summary/Keyword: OT

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What is the Potential of Animal Models to Inform Occupational Therapy Theories and Interventions From the Perspective of Neuroscience? (신경과학적 관점으로 본 작업치료에서 동물 모델의 필요성)

  • Park, Ji-Hyuk;Ahmad, S. Omar
    • Therapeutic Science for Rehabilitation
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    • v.1 no.1
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    • pp.39-56
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    • 2012
  • Introduction : Animal studies cannot be applied directly to Occupational Therapy(OT) intervention protocol. However, animal models still provide essential evidences and knowledge to improve OT practice and to develop OT theories as well as human studies do. The purpose of this scholarly paper is to explore the potential of animal models to inform OT theory and practice particularly as it relates to neuroscience. Body : The animal models provide related knowledge for a better understanding of the mechanism of diseases and related neural networks. Based on this knowledge, researchers can test their hypothesis of neural disease. In addition, accumulated animal studies contribute to introduce the new approaches to human diseases and to improve the effectiveness of treatment. Conclusions : Animal models of neurological disease are critical and have the potential to improve OT practice and theory in many ways. Therefore, OT researchers need to pay more attention to animal models in addition human studies.

The influence of systemically administered oxytocin on the implant-bone interface area: an experimental study in the rabbit

  • Cho, Sung-Am;Park, Sang-Hun;Cho, Jin-Hyun
    • The Journal of Advanced Prosthodontics
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    • v.6 no.6
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    • pp.505-511
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    • 2014
  • PURPOSE. The purpose of this study was to assess the effect of systemically administered oxytocin (OT) on the implant-bone interface by using histomorphometric analysis and the removal torque test. MATERIALS AND METHODS. A total of 10 adult, New Zealand white, female rabbits were used in this experiment. We placed 2 implants (CSM; CSM Implant, Daegu, South Korea) in each distal femoral metaphysis on both the right and left sides; the implants on both sides were placed 10 mm apart. In each rabbit, 1 implant was prepared for histomorphometric analysis and the other 3 were prepared for the removal torque test (RT). The animals received intramuscular injections of either saline (control group; 0.15 M NaCl) or OT (experimental group; $200{\mu}g/rabbit$). The injections were initiated on Day 3 following the implant surgery and were continued for 4 subsequent weeks; the injections were administered twice per day (at a 12-h interval), for 2 days per week. RESULTS. While no statistically significant difference was observed between the two groups (P=.787), the control group had stronger removal torque values. The serum OT concentration (ELISA value) was higher in the OT-treated group, although no statistically significant difference was found. Further, the histomorphometric parameter (bone-to-implant contact [BIC], inter-thread bone, and peri-implant bone) values were higher in the experimental group, but the differences were not significant. CONCLUSION. We postulate that OT supplementation via intramuscular injection weakly contributes to the bone response at the implant-bone interface in rabbits. Therefore, higher concentrations or more frequent administration of OT may be required for a greater bone response to the implant. Further studies analyzing these aspects are needed.

A Study on Wadding Dresses for Women in the Latter Period of Chosun (조선후기 여자 혼례복에 관한 연구)

  • 전혜숙;김숙경
    • The Research Journal of the Costume Culture
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    • v.10 no.2
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    • pp.160-177
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    • 2002
  • Wedding ceremony is a most basic and significant rite of religion. Clothing fur the ceremony is also assumed religious in essence. Thus this study focuses on ideas and religious qualities implied in wedding dresses for women in the latter period of Chosen. Among those wedding dresses for women in the public class, in this study, Yeom-Eui(염의), Won-Sam(원삼) in green and Hwal-Ot(활옷) are discussed. Yeom-Eui seemed preferred by only some of the nobel class who still considered manners and customs as very important. The rest people often wore a brilliant Hwal-Ot rather than Yeom-Eui under influences of a loosened social position system and sumptuous moods. Since a wedding is the reflection of social condition and at the same time a religious rite, the above mentioned difference in wedding dresses between the class of scholars obsessed with Confucianism and the rest public seems attributable to differences in values and religious views between the two groups. Of course, Hwal-Ot was also transmitted from the Chinese nation of Tang, so it complied with a contemporary flunkeyism about Chinese culture. Won-Sam and Hwal-Ot were designed with patterns representing the very significance of wedding and those wishing worldly blessings more children and more sons, longevity and wealth and prosperity. The fact that wishes of more children and more sons were more often implied by patterns of wedding dress in the latter Chosen indicates the legitimate oldest son-oriented patriarchical family system at that time influenced to such contemporary dresses. Meanwhile, those patterns used for Won-Sam and Hawl-Ot were influenced mainly by Confucianism, but sometimes based on Buddhism and Taoism. It suggests that the Chosun dynasty emphasized Confucian manners and customs to restore previous values which had been about to be collapsed since wars with the Chinese Ching and Japan, but nevertheless in the public class, Buddhism and Taoism were more deeply prevailed. This was supported by patterns and colors shown in wedding clothing.

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A Survey on the Awareness of Occupational Therapists by the Adult Day Care Center Staff in Korea: Focusing on Managers or Center Directors (국내 노인 주간보호시설 종사자의 작업치료사에 대한 인식조사 : 관리자 또는 시설장을 중심으로)

  • Kim, Min-Ho;Park, Sung-Ho
    • Journal of The Korean Society of Integrative Medicine
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    • v.9 no.1
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    • pp.91-100
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    • 2021
  • Purpose : This study aims to investigate the awareness of occupational therapists among managers and directors of adult day care centers in Korea to explore the cause of the low employment rate of these therapists and offer the results as basic data that can be used to expand occupational therapy at adult day care centers. Methods : This study collected data by conducting an online questionnaire with managers and directors of adult day care centers located in Seoul, Busan, Incheon, Daejeon, Gwangju, and Ulsan. A total of 70 completed questionnaires were divided into two groups a 'group with experience in occupational therapy information (OT experience)' and a 'group with no experience in occupational therapy information (OT inexperience)' and analyzed. Results : First, the 'OT experience' was found to have higher levels of awareness of the scope of work of occupational therapists than the 'OT inexperience'. Second, significant differences were found in the degree of awareness and necessity of occupational therapists and plans to employ occupational therapists later between the 'OT experience' and the 'OT inexperience'. Third, it was shown that there were significant correlations between whether the respondents were familiar with occupational therapy and the degree of awareness and necessity of occupational therapists and plans to employ occupational therapists later. Conclusion : Based on these findings, the following measures are recommended to expand the area of occupational therapy in adult day care centers, the need for occupational therapists should be mentioned in the health and welfare-related education for workers at these adult day care centers, policies such as a medical fee system for occupational therapy at these adult day care centers should be prepared.

Parents Response for the Therapy Support Services Provided by Center for Special Education - Centered on Parents of Occupational Therapy Support Service - (특수교육지원센터 치료지원서비스에 대한 견해 - 작업치료 서비스를 받는 보호자를 중심으로 -)

  • Song, Min-Ok;Lee, Sung-Ja;Kim, Hun-Ju
    • The Journal of Korean Academy of Sensory Integration
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    • v.8 no.1
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    • pp.51-60
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    • 2010
  • Objective : The purpose of this study is to provide practical guidelines for the better performance of the Occupational therapy services(OT services) in the Supporting Center for Special Education. The study is based upon the quality and satisfaction of the OT services, measured by interviewing parents whose children have taken the services provided by Ulsan Kang-Nam Supporting Center for Special Education. Methods : Five parents for the children having OT services since March, 2010 in the Kang-Nam Supporting Center were interviewed individually. The interview per each person took thirty to fifty minutes and was all audio-recorded. Results : The satisfaction of the qualification for the OT therapists working at the Kang-Nam Supporting Center was high. The quality for treatment facilities and the variety for treatment materials met the expectation for OT to be well-performed. The free OT treatment system was the one of significant features for the OT services provided by the Kang-Nam Supporting Center. However, the perception of the interviewed parents for the OT was very low.

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Ovarian Transposition for Stage Ib Squamous Cell Cervical Cancer - Lack of Effects on Survival Rates?

  • Turan, A. Taner;Keskin, H. Levent;Dundar, Betul;Gundogdu, Burcu;Ozgul, Nejat;Boran, Nurettin;Tulunay, Gokhan;Kose, M. Faruk
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.1
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    • pp.133-137
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    • 2013
  • Background: To investigate the impact of ovarian transposition (OT) on survival rates of the patients with stage Ib squamous cell cervical cancer. Materials and Methods: Ninety-two subjects who underwent a radical hysterectomy including oophorectomy were evaluated. For nineteen (20.7%), OT was performed. Patients were divided into two groups, OT versus oophorectomy alone. The primary end-point of this study was to investigate the impact of OT on tumor recurrence rate and time, 5-year disease-free survival (DFS) and overall survival (OS). These comparisons were performed for subgroups including patients who received radiotherapy versus who did not. Statistical analyses were conducted using the Chi-square test, T-test and Mann-Whitney test. OS was examined using the Kaplan-Meier method. $P{\leq}0.05$ was considered to be statistically significant. Results: The median follow-up period was 89 months for OT and 81 months for the oophorectomy group (p>0.05). Both groups experienced similar recurrence rates (31.6% vs. 26.4%, p=0.181). The median duration from surgery to recurrence, and surgery to death were also similar between the groups (p>0.05). The 5-year DFS and OS rates were both 68.4% for the OT group, and 73.6% and 77.8% for the oophorectomy group (p=0.457 and p=0.307, respectively). While the 5-year DFS rate was not statistically significant between the OT and oophorectomy groups who did not receive radiotherapy (p=0.148), the 5-year OS rate was significantly higher in the oophorectomy group (95.4% vs 66.7%, respectively) without radiotherapy (p=0.05). The 5-year DFS and OS rates were statistically similar between the groups who received adjuvant radiotherapy (p>0.05). Conclusions: Ovarian transposition has not significantly negative effect on the survival rates when adjuvant radiotherapy will be applied, while 5-year OS may be less in OT group if radiotherapy is not mandatory.

Perception of Long-Term Oxygen Therapy for Chronic Lung Diseases May Affect Poor Adherence in Korea

  • Hyo Jin Kim;Hongyeul Lee;Ji Young Yang;Jae Ha Lee;Seung Won Ra;SungMin Hong;Ho Young Lee;Sung Hyun Kim;Mi-Yeong Kim;Hyun-Kyung Lee
    • Tuberculosis and Respiratory Diseases
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    • v.87 no.1
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    • pp.100-114
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    • 2024
  • Background: Long-term oxygen therapy (LTOT) improves the survival of patients with hypoxemia due to chronic respiratory diseases. The clinical outcomes of LTOT are strongly associated with patient adherence. To improve the adherence of patients, physicians have focused on the efficacy of LTOT. However, poor adherence may stem from patients' perceptions of LTOT. Herein we evaluated patients' perceptions of LTOT affecting adherence. Methods: We conducted a cross-sectional survey study using descriptive, open, and closed-ended questionnaire. Patients using oxygen therapy (OT) or requiring it but avoiding OT responded to the questionnaires at three university hospitals. Results: Seventy-nine patients responded to the questionnaires. The number of patients using home and portable OT was 69 (93%) and 37 (46.3%), respectively. Patients with good adherence were 22 (30.1%). Among patients with good adherence, 90.9% used oxygen according to physicians' prescriptions whereas only 37.3% of those with poor adherence followed physicians' prescriptions (p<0.01). The reasons for avoiding using home OT were fear of permanent use (50%), unwanted attention (40%), and lack of symptoms (40%). They avoided portable OT because of unwanted attention (39%), heaviness (31.7%), and lack of symptoms (21.6%). Conclusion: Patients on LTOT had the perception of the misunderstanding the effects of OT and of psychosocial barriers to initiate or use LTOT. Considering these findings, health professionals need to provide effective education on the purpose of LTOT to improve patient adherence to OT and provide sufficient support for the management of psychosocial barriers in patients using LTOT.

Blockade of STAT3 in T Cells Inhibits Germinal Center Reactions against Intranasal Allergens

  • Choi, Garam;Chung, Yeonseok
    • Biomolecules & Therapeutics
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    • v.24 no.3
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    • pp.244-251
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    • 2016
  • Understanding the developmental mechanisms of humoral immunity against intranasal antigens is essential for the development of therapeutic approaches against air-borne pathogens as well as allergen-induced pulmonary inflammation. Follicular helper T (Tfh) cells expressing CXCR5 are required for humoral immunity by providing IL-21 and ICOS costimulation to activated B cells. However, the regulation of Tfh cell responses against intranasal antigens remains unclear. Here, we found that the generation of Tfh cells and germinal center B cells in the bronchial lymph node against intranasal proteinase antigens was independent of $TGF-{\beta}$. In contrast, administration of STAT3 inhibitor STA-21 suppressed the generation of Tfh cells and germinal center B cells. Compared with wild-type OT-II T cells, STAT3-deficient OT-II T cells transferred into recipients lacking T cells not only showed significantly reduced frequency Tfh cells, but also induced diminished IgG as well as IgE specific for the intranasal antigens. Cotransfer study of wild-type OT-II and STAT3-deficient OT-II T cells revealed that the latter failed to differentiate into Tfh cells. These findings demonstrate that T cell-intrinsic STAT3 is required for the generation of Tfh cells to intranasal antigens and that targeting STAT3 might be an effective approach to ameliorate antibody-mediated pathology in the lung.

A Study on the Design for a Boll Jointed Doll's Costume with the Ladies' Vogue of Bok-yo in the Early-middle Joseon Dynasty (조선 초.중기 양반부녀복식의 복요(服妖) 유행을 응용한 구체관절인형 고증의상 디자인 연구)

  • Choi, Hae-Yool
    • Journal of the Korean Society of Clothing and Textiles
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    • v.33 no.9
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    • pp.1386-1397
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    • 2009
  • This study investigates costumes for ball jointed dolls under the theme of Bok-yo(服妖): The Lady in Early-middle Joseon with relic costumes as a reference. The Bok-yo style was spread universally for Joseon women in the $15^{th}-16^{th}$ centuries, but it is an uncommon theme in the area of media and traditional costume for dolls. Bok-yo (curious outfit), consisted of a Dang-jeogori with a golden brocade in the front bottom, manlike Jang-ot, wide Chima, and Jang-ot was dressed between Chima and the Dang-jeogori. To make correct patterns and approvals for idle bodies of female ball-jointed dolls, darts are added in the front vertical line and center back of the golden brocade Dan-jeogori for Joseon ladies. The pattern of the golden brocade Chima is made as a trapezoid shape for the thin waist of a doll, and the length of a deep-greened silk gauze The Jang-ot increased because of the length of the doll's legs. In addition, the kinds of investigated accessories, hair, traditional underwear for dolls are limited. Suggested is a closer cooperation between the investigated costume designers, doll companies, and accessory makers for the future market of ball jointed dolls.

Unavailability Analysis of OP$\Delta$T & OT$\Delta$T Channel by Direct Simulation Method (직접 모의방식에 의한 OP$\Delta$T & OT$\Delta$T 찬넬의 비가용도 분석)

  • Yun, Won-Young;Park, In-Yong
    • Nuclear Engineering and Technology
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    • v.19 no.3
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    • pp.186-191
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    • 1987
  • In this paper, we suggest the simple and practical direct simulation method for the system reliability calculation In the aspect of system unavailability calculation, this method can simplify the calculation process by applying the hard-wired system fault tree. For the calculation purpose, we use the ESCAF which is developed by Mr. Laviron in France. As a consequence, we estimate the unavailability of OP$\Delta$T & OT$\Delta$T channel in W PWR plants as a value of 8.17576$\times$10$^{-9}$ from IEEE std. 500-1977's reference data. In our calculation, the processing time is no more than 25 sec.

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