Loh, Yean Chun;Tan, Chu Shan;Yam, Mun Fei;Oo, Chuan Wei;Omar, Wan Maznah Wan
Journal of Pharmacopuncture
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v.21
no.3
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pp.203-206
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2018
Objectives: There is an increasing number of complex diseases that are progressively more difficult to be controlled using the conventional "single compound, single target" approach as demonstrated in our current modern drug development. TCM might be the new cornerstone of treatment alternative when the current treatment option is no longer as effective or that we have exhausted it as an option. Orthogonal stimulus-response compatibility group study is one of the most frequently employed formulas to produce optimal herbal combination for treatment of multi-syndromic diseases. This approach could solve the relatively low efficacy single drug therapy usage and chronic adverse effects caused by long terms administration of drugs that has been reported in the field of pharmacology and medicine Methods: The present review was based on the Science Direct database search for those related to the TCM and the development of antihypertensive TCM herbal combination using orthogonal stimulus-response compatibility group studies approach. Results: Recent studies have demonstrated that the orthogonal stimulus-response compatibility group study approach was most frequently used to formulate TCM herbal combination based on the TCM principles upon the selection of herbs, and the resulting formulated TCM formula exhibited desired outcomes in treating one of global concerned complex multi-syndromic diseases, the hypertension. These promising therapeutic effects were claimed to have been attributed by the holistic signaling mechanism pathways employed by the crude combination of herbs. Conclusion: The present review could serve as a guide and prove the feasibility of TCM principles to be used for future pharmacological drug research development.
Journal of the Korean Association of Oral and Maxillofacial Surgeons
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v.44
no.1
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pp.12-17
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2018
Objectives: Airway management in patients with panfacial trauma is complicated. In addition to involving facial lesions, such trauma compromises the airway, and the use of intermaxillary fixation makes it difficult to secure ventilation by usual approaches (nasotracheal or endotracheal intubation). Submental airway derivation is an alternative to tracheostomy and nasotracheal intubation, allowing a permeable airway with minimal complications in complex patients. Materials and Methods: This is a descriptive, retrospective study based on a review of medical records of all patients with facial trauma from January 2003 to May 2015. In total, 31 patients with complex factures requiring submental airway derivation were included. No complications such as bleeding, infection, vascular, glandular, or nervous lesions were presented in any of the patients. Results: The use of submental airway derivation is a simple, safe, and easy method to ensure airway management. Moreover, it allows an easier reconstruction. Conclusion: Based on these results, we concluded that, if the relevant steps are followed, the use of submental intubation in the treatment of patients with complex facial trauma is a safe and effective option.
The seismic provisions of the current edition (2005) of the National Building Code of Canada (NBCC) differ significantly from the earlier edition. The current seismic provisions are based on the uniform hazard spectra corresponding to 2% probability of exceedance in 50 years, as opposed to the seismic hazard level with 10% probablity of exeedance in 50 years used in the earlier edition. Moreover, the current code is presented in an objective-based format where the design is performed based on an acceptable solution. In the light of these changes, an assessment of the expected performance of the buildings designed according to the requirements of the current edition of NBCC would be very useful. In this paper, the seismic performance of a set of six, twelve, and eighteen story buildings of regular geometry and with concrete moment resisting frames, designed for Vancouver western Canada, has been evaluated. Although the effects of non-structural elements are not considered in the design, the non-structural elements connected to the lateral load resisting systems affect the seismic performance of a building. To simulate the non-structural elements, infill panels are included in some frame models. Spectrum compatible artificial ground motion records and scaled actual accelerograms have been used for evaluating the dynamic response. The performance has been evaluated for each building under various levels of seismic hazard with different probabilities of exceedance. From the study it has been observed that, although all the buildings achieved the life-safety performance as assumed in the design provisions of the building code, their performance characteristics are found to be non-uniform.
Electric vehicles (EVs) are spreading rapidly and many counties are promoting hybrid and fully EVs through legislation. Therefore, an increasing amount of lithium ion batteries will reach the end of their usable life and will require effective and sustainable end-of-life management plan which include landfill disposal or incineration. The current research focuses on more sustainable methods such as remanufacturing, reuse and recycling in order to prepare for future battery compositions and provide insights to the need recycling methods to be developed to handle large amounts of batteries sustainably in the near future. The two most prominent material recovery techniques are hydrometallurgy and pyrometallurgy which are explored and assessed on their relative effectiveness, sustainability, and feasibility. Hydrometallurgy is a superior recycling method due to high material recovery and purity, very low emissions, high prevalence of chemical reuse and implementation of environmentally sustainable compounds. Expanding recycling technologies globally should take the research and technologies pioneered by Umicore to establish a sustainable recycling program for end-of-life EVs batteries. Emerging battery technology of Telsa show the most effective designs for high performance batteries includes the use of silicon which is expected to increase capacity of batteries in the future.
NGUYEN, Loan Thi;NGUYEN, Anh Hong Viet;LE, Hac Dinh;LE, Anh Hoang;TRUONG, Tu Tuan Vu
The Journal of Asian Finance, Economics and Business
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v.7
no.8
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pp.103-115
/
2020
In many countries, the Government enacts tax laws in order to manage tax collection and regulate the macro-economy. According to Noor, Jamaludin, Omar, and Aziz (2013), tax non-compliance is a growing concern because of its negative effects on the state budget. The main objectives of this article are to identify the factors affecting corporate income tax non-compliance of enterprises in Ho Chi Minh City in accordance with the current situation of Vietnamese tax administration. We use several research methods, including the exploitation of information and practical experiences from both taxpayers and tax authorities; with Probit regression model on a sample of 187 enterprises that have been inspected or examined by tax authorities in Vietnam during the period from 2013 to 2017.The article identified eight factors affecting corporate income tax (CIT) non-compliance: (1) working capital/total assets; (2) revenue/total assets; (3) total debt/total assets; (4) loss in the previous year; (5) receivables/revenue; (6) the size of enterprises; (7) tax administrative penalties/tax payable; and (8) business field. In particular, the tax non-compliance was studied as a violation of Vietnamese tax laws by enterprises declaring an insufficient amount of CIT payable to the State budget.
MUHARDI, Muhardi;CINTYAWATI, Cici;ADWIYAH, Rabiatul;HAMI, Norsiah;HASHIM, Rushanim;OMAR, Salmah;SHAFIE, Shafini Mohd
The Journal of Asian Finance, Economics and Business
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v.7
no.11
/
pp.1041-1047
/
2020
The intention of this paper is to give a better understanding about the implementation of sustainable manufacturing practice in the textile companies in Indonesia as one of the promising sectors in the manufacturing industry. The data was collected by taking a case study approach in one of the leading textile companies in Indonesia. Questionnaire and interview techniques were used to gather in-depth information about the implementation of a sustainable concept in the company. The result reveals that the extent of the implementation of Sustainable Manufacturing Practices (SMP) in the companies are at a level of moderate to high. From the three dimensions measured which are environment, economy, and social dimensions, the evaluation result shows good performance in terms of the implementation of sustainable concepts, like low level of gas emission, high percentage of renewable energy usage, cost reduction rate, high quality of life, etc. From this result, the authors then develop a sustainable manufacturing model in the wider coverage to be implemented not only in the textile industry but is expected to be implemented in manufacturing sectors as well. This model consists of at least seven basic archetypes which are divided into three dominant areas: technological innovation, economical, and social areas which aim to bring better performance in the manufacturing industry of Indonesia.
Journal of Information Science Theory and Practice
/
v.2
no.4
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pp.31-48
/
2014
The proliferation of many interactive Topic Detection and Tracking (iTDT) systems has motivated researchers to design systems that can track and detect news better. iTDT focuses on user interaction, user evaluation, and user interfaces. Recently, increasing effort has been devoted to user interfaces to improve TDT systems by investigating not just the user interaction aspect but also user and task oriented evaluation. This study investigates the combination of the bag of words and named entities approaches implemented in the iTDT interface, called Interactive Event Tracking (iEvent), including what TDT tasks these approaches facilitate. iEvent is composed of three components, which are Cluster View (CV), Document View (DV), and Term View (TV). User experiments have been carried out amongst journalists to compare three settings of iEvent: Setup 1 and Setup 2 (baseline setups), and Setup 3 (experimental setup). Setup 1 used bag of words and Setup 2 used named entities, while Setup 3 used a combination of bag of words and named entities. Journalists were asked to perform TDT tasks: Tracking and Detection. Findings revealed that the combination of bag of words and named entities approaches generally facilitated the journalists to perform well in the TDT tasks. This study has confirmed that the combination approach in iTDT is useful and enhanced the effectiveness of users' performance in performing the TDT tasks. It gives suggestions on the features with their approaches which facilitated the journalists in performing the TDT tasks.
DOTIFS is a new multi-object Integral Field Spectrograph (IFS) being designed and fabricated by the Inter-University Center for Astronomy and Astrophysics, Pune, India, (IUCAA) for the Cassegrain side port of the 3.6m Devasthal Optical Telescope (DOT). The telescope is constructed by the Aryabhatta Research Institute of Observational Sciences, Nainital (ARIES). Its main scientific objectives are the physics and kinematics of the ionized gas, star formation and H II regions in nearby galaxies. It is a novel instrument in terms of multi-IFU, built in deployment system, and high throughput. It consists of one magnifier, 16 integral field units (IFUs), and 8 spectrographs. Each IFU is comprised of a microlens array and 144 optical fibers, and has $7.4^{\prime\prime}{\times}8.7^{\prime\prime}$ field of view with 144 spaxel elements with a sampling of 0.8" hexagonal aperture. The IFUs can be deployed on the telescope side port over an 8' diameter focal plane by x-y actuators. 8 Identical, all refractive, dedicated fiber spectrographs will produce 2,304 R~1800 spectra over 370-740nm wavelength range with single exposure. Currently, conceptual and baseline design review had been done, and is in the critical design phase with a review planned for later this year. Some of the components have already arrived. The instrument will see its first light in 2015.
Al-Osta, Mohammed A.;Baig, Mirza G.;Al-Malack, Muhammad H.;Al-Amoudi, Omar S. Baghabra
Advances in concrete construction
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v.4
no.2
/
pp.123-143
/
2016
Use of heavy fuel fly ash (HFFA) (diesel and cracked fuel) for power generation in Saudi Arabia has generated and accumulated large quantities of HFFA as a byproduct. In this research, HFFA is studied with the emphasis on the utilization of this waste material in concrete blocks and asphalt concrete mixes. Two types of mixes, one with low and other with high cement content, were studied for concrete blocks. Different mixes having varying percentages of HFFA (0% to 25%), as cement/sand replacement or as an additive, were studied. The performance of concrete blocks is evaluated in terms of compressive strength, water absorption, durability and environmental concerns. The results showed that blocks cannot be cast if more than 15% HFFA is used; also there is a marginal reduction in the strength of all the mixes before and after being exposed to the sulfate solution for a period of ten months. HFFA is studied in asphalt concrete mixes in two ways, as an asphalt modifier (3&5%) and as a filler (50%) replacement, the results showed an improvement in stiffness and fatigue life of mixes. However, the stability and indirect tensile strength loss were found to be high as compared to the control mix due to moisture damage, indicating a need of using antistripping agents. On environmental concerns, it was found that most of the concerned elements are within acceptable limits also it is observed that lower concentration of barium is leached out with the higher HFFA concentrations, which indicates that HFFA may work as an adsorbent for this leaching element.
Hesham, Abd El-Latif;Mostafa, Yasser S.;AlSharqi, Laila Essa Omar
Mycobiology
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v.48
no.2
/
pp.122-132
/
2020
Citric acid is a commercially valuable organic acid widely used in food, pharmaceutical, and beverage industries. In this study, 260 yeast strains were isolated from soil, bread, juices, and fruits wastes and preliminarily screened using bromocresol green agar plates for their ability to produce organic acids. Overall, 251 yeast isolates showed positive results, with yellow halos surrounding the colonies. Citric acid production by 20 promising isolates was evaluated using both free and immobilized cell techniques. Results showed that citric acid production by immobilized cells (30-40 g/L) was greater than that of freely suspended cells (8-19 g/L). Of the 20 isolates, two (KKU-L42 and KKU-L53) were selected for further analysis based on their citric acid production levels. Immobilized KKU-L42 cells had a higher citric acid production rate (62.5%), while immobilized KKU-L53 cells showed an ~52.2% increase in citric acid production compared with free cells. The two isolates were accurately identified by amplification and sequence analysis of the 26S rRNA gene D1/D2 domain, with GenBank-based sequence comparison confirming that isolates KKU-L42 and KKU-L53 were Candida tropicalis and Pichia kluyveri, respectively. Several factors, including fermentation period, pH, temperature, and carbon and nitrogen source, were optimized for enhanced production of citric acid by both isolates. Maximum production was achieved at fermentation period of 5 days at pH 5.0 with glucose as a carbon source by both isolates. The optimum incubation temperature for citric acid production by C. tropicalis was 32 ℃, with NH4Cl the best nitrogen source, while maximum citric acid by P. kluyveri was observed at 27 ℃ with (NH4)2 SO4 as the nitrogen source. Citric acid production was maintained for about four repeated batches over a period of 20 days. Our results suggest that apple and banana wastes are potential sources of novel yeast strains; C. tropicalis and P. kluyveri which could be used for commercial citric acid production.
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