• 한국가시화정보학회지
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• 제3권1호
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• pp.63-70
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• 2005

Optical Line Patternator(OLP) has been applied to get a distribution of the spray at high ambient pressure. OLP is a combined technique of extinction measurement and image processing. The attenuated intensity of laser beam after traversing spray region was measured by using a photo-detector, and the line image of Mie-scattering was captured simultaneously in the path of each laser beam by using a CCD camera. The distribution of extinction coefficient in the spray is obtained by processing these data with the algebraic reconstruction technique. From the distribution of extinction coefficient, the surface distribution of spray can be reconstructed. OLP does not use laser sheet but use laser beam so that the noise effect of multiple scattering, caused by increasing number density of droplet in high pressure environment, is reduced drastically. OLP is expected as a suitable method which can investigate the characteristics of relatively large spray under the high pressure environment such as liquid rocket engine.

• International Journal of Control, Automation, and Systems
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• 제3권1호
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• pp.32-42
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• 2005

In this paper, to improve the efficiency of welding and user convenience in the shipbuilding industry, a PC-based off-line programming (OLP) technique and the development of a robot transfer unit are presented. The developed OLP system is capable of not only robot motion simulations but also automatic generations of a series of robot programs. The strength of the developed OLP system lies in its flexibility in handling the changes of the welding robot's target objects. Moreover, for a precise transfer of the robot to a desired location, an auxiliary mobile platform named a robot-origin-transfer-unit (ROTU) was developed. To enhance the cornering capability of the platform in a narrow area, the developed ROTU is equipped with 2 steering wheels and 1 driving wheel. Both the OLP and the ROTU were field­tested and their performances were proven successful.

• Journal of Oral Medicine and Pain
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• 제47권3호
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• pp.161-166
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• 2022

Oral lichen planus (OLP) is a chronic oral mucosal disease affecting the buccal cheek, tongue, palate, lip, and gingival mucosa. Lesions in the gingiva make it difficult to control dental plaque due to pain. As a result, the disease is often accompanied by gingivitis or periodontitis. If OLP and dental plaque are not properly managed, the patient's periodontal condition will worsen. Thus, clinicians treating OLP should emphasize periodic visits and dental plaque control. Here, we report the management of a patient who struggled with OLP for 20 years and discuss the importance of periodic regular observations and active periodontal management.

• 구강회복응용과학지
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• 제31권4호
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• pp.371-377
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• 2015

편평태선은 피부, 점막에 양측성 또는 다발성의 병소가 만성으로 나타나는 흔한 질환이다. 편평태선을 발생시키는 원인으로는 구강 내 수복물, 전신질환, 약물, 스트레스 등 여러 가지 요인이 작용한다고 알려져 있다. 그 중 편평태선에 대한 구강 내 수복물과 위생관리의 영향은 치과 영역에서 큰 관심이 되어왔다. 본 증례는 형태가 불량하고 경계가 잘 맞지 않는 보철물이 수복되어 있는 편평태선 환자에 관한 것이다. 환자는 오랜 시간 동안 편평태선으로 치료받고 있었고 양측 구치부에 금속도재관을 수복한 이후 증상이 더욱 악화되어 있었다. 불량한 적합도와 외형을 보이는 금속도재관을 제거하고 치주치료를 동반하여 보철물의 형태와 변연 적합도를 개선시킴으로써 편평태선이 효과적으로 줄어들었기에 다음을 보고자 한다.

• Asian Pacific Journal of Cancer Prevention
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• 제14권11호
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• pp.6979-6983
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• 2013

Background: Oral lichen planus (OLP) is categorized as premalignant lesion although its malignant potential is a matter of controversy. The objective of this study was to investigate Ki67 expression in OLP, oral epithelial dysplasia and oral squamous cell carcinoma (OSCC). Materials and Methods: Expression of Ki67 was evaluated through immunohistochemistry (IHC) in groups of A (17 cases of epithelial hyperplasia), B (16 cases of OLP), C1 (10 cases of mild epithelial dysplasia), C2 (10 cases of severe epithelial dysplasia), D1 (10 cases of well-differentiated OSCC), and D2 (10 cases of poorly-differentiated OSCC). Results: There was a significant difference in Ki67 expression based on quantitative analysis among the six studied groups as well as group B compared bilaterally with groups C2, D1 and D2 (p< 0.0001). However, there was no significant difference between groups B and C1 or between groups D1 and D2 (p> 0.05). Conclusions: Based on the results of the present study it may not be possible to definitely consider malignant transformation potential for OLP. However, expression of Ki67 was significantly higher in OLP than that of epithelial hyperplasia with no significant difference from that of mild epithelial dysplasia. This should be considered by clinicians to carefully and regularly follow up OLP lesions to detect potential subtle changes at an early stage.

• International Journal of Oral Biology
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• 제45권1호
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• pp.1-7
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• 2020

Oral lichen planus (OLP) is a chronic inflammatory disease observed in approximately 0.5-2.2% of the population, and it is recognized as a premalignant lesion that can progress into oral squamous cell carcinoma (OSCC). The rate of malignant transformation is approximately 1.09-2.3%, and the risk factors for malignant transformation are age, female, erosive type, and tongue site location. Malignant transformation of OLP is likely related to the low frequency of apoptotic phenomena. Therefore, apoptosis-related genetic factors, like p53, BCL-2, and BAX are reviewed. Increased p53 expression and altered expression of BCL-2 and BAX were observed in OLP patients, and the malignant transformation rate in these patients was relatively higher. The involvement of microRNA (miRNA) in the malignant transformation of OLP is also reviewed. Because autophagy is involved in cell survival and death through the regulation of various cellular processes, autophagy-related genetic factors may function as factors for malignant transformation. In OLP, decreased levels of ATG9B mRNA and a higher expression of IGF1 were observed, suggesting a reduction in cell death and autophagic response. Activated IGF1-PI3K/AKT/mTor cascade may play an important role in a signaling pathway related to the malignant transformation of OLP to OSCC. Recent research has shown that miRNAs, such as miR-199 and miR-122, activate the cascade, increasing the prosurvival and proproliferative signals.

• Journal of Dental Anesthesia and Pain Medicine
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• 제22권6호
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• pp.405-417
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• 2022

Oral lichen planus (OLP) is a chronic inflammatory immune-mediated condition that has been identified as a potentially malignant oral disorder. Various therapies have been proposed for its management as alternative to corticosteroids. However, no definitive treatment has been identified that can result in complete remission or minimal recurrence. Hyaluronic acid has recently been used as an alternative therapy for the management of OLP. This study aimed to systematically review the effectiveness of Hyaluronic acid in the management of symptomatic OLP. Online electronic databases and manual searches were performed for randomized controlled trials (RCTs) published in English between January 2010 and April 2022. RCTs were identified that compared the efficacy of hyaluronic acid and other interventional therapies at baseline and during follow-up. The Cochrane Risk of Bias tool was used to assess the quality of the included studies. Visual analog scale (VAS) scores, Thongprasom sign scores, lesion size, degree of erythema, clinical severity, and disease severity were assessed both quantitatively and qualitatively. Seven studies were analyzed. Five studies reported a high risk of bias while the remaining two studies reported an unclear risk of bias. The overall quantitative assessment of size, symptoms, degree of erythema, and sign score in OLP lesions treated with HA was not statistically significant compared to that in the control group (P > 0.05). In addition, subgroup analysis comparing HA with placebo or corticosteroids did not yield statistically significant (P > 0.05) results. Qualitatively, both HA and tacrolimus resulted in an effective reduction in signs and symptoms. Clinical/disease severity index/scores were inconsistent. A high degree of heterogeneity was observed among the included studies. None of the included studies reported the side effects of HA. These findings suggest that corticosteroids, tacrolimus, placebo, and HA could be equally effective in OLP management. The clinical/disease severity index or score reduction cannot be determined with certainty. Thus, OLP can be treated with HA as an alternative therapy. Owing to limited clinical trials on HA, high heterogeneity, and high risk of bias in the included studies, definitive conclusions cannot be derived.

• 대한기계학회논문집
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• 제19권2호
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• pp.568-579
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• 1995

An off-line programming (OLP) system was proposed and developed in order to save cost and time in adjusting a robot to new workcells or applying new algorithms to actual trajectory planning. The developed OLP system was especially designed to be operated in a PC level host computer. A SCARA robot with four axes was selected as an objective robot. The OLP system developed in this study consisted of such modules as data base, three-dimensional graphics, kinematics, trajectory planning, dynamics, control, and commands. Each module was constructed to form an independent unit so that it can be easily modified or improved. The OLP system was programmed for a graphic user interface in Borland $C^{++}$ language. Some of system operating commands and an interpreter were devised and used for more convenient programming of robot simulations.s.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 1997년도 한국자동제어학술회의논문집; 한국전력공사 서울연수원; 17-18 Oct. 1997
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• pp.1840-1843
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• 1997

The task environment of a robot is changing rapidly and task itself becomes complicated due to current industrial trends of multi-product and small lot size production. A convenient user-interfaced off-line programming(OLP) system is being developed in order to overcome the difficulty in teaching a robot task. Using the OLP system, operators can easily teach robot tasks off-line and verify feasibility of the task through simulation of a robot prior to the on-line execution. However, some task errors are inevitable by kinematic differences between the robot model in OLP and the actual robot. Three calibration methods using image information are proposed to compensate the kinematic differences. These methods compose of a relative position vector method, three point compensation method, and base line compensation method. To compensate a kinematic differences the vision system with one monochrome camera is used in the calibration experiment.

• Journal of Welding and Joining
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• 제14권1호
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• pp.30-37
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• 1996

조선에서 추진되어온 용접로봇의 적용은 주로 대조립 용접공정의 자동화로서, 갠트리(Gantry)에 용접토치를 장착한 로봇을 설치하여 구성하였다. 이러한 시스템에 서의 용접은 로봇을 용접부위까지 이송시킨 후 로봇의 구동으로 용접을 수행하거나, 또는 로봇과 캔트리의 동시 구동으로 용접을 수행하기도 한다. 또한 이 공정은 복잡 한 용접구조물을 OLP(Off-Line Programming)를 이용하여 교시하므로서 효과적인 자동 화 시스템의 구성이 가능할 수 있었다. 소조립 공정은 대조립공정과 비교하면 더 간단 한 부재의 용접이라 할 수 있으나 공정과 공장의 생산방법에 따라 자동화의 어려움은 따른다. 적용되는 매니프레이타는 소조립 공정의 특성에 맞게 그 형태가 설계되어야 하고 이를 운용하는 시스템은 소조립 생산방법에 맞게 통합, 개발되는 Task-Based System"이 되어야 한다. 특히 소조립 공정은 대조립 공정과 달리 여러가지 용접 판넬 을 동시에 이송시킨 후 용접함으로서 OLP의 직접 적용을 어렵게 하는 요인이 있어 이것을 해결하는 것이 생산성을 증가시키는데 적지 않은 영향을 미친다 하겠다. 이 글에서는 소조립 용접 자동화를 구성하기 위해 필요한 젓으로서 소조립 용접 공정을 소개하고, 공정의 특성에 맞도록 설계된 매니퓰레이타 시스템과, OLP, 판넬인식, 자동 교시 모들로 이루어지는 작업인식 시스템에 관해 기술한다.기술한다.