• Title/Summary/Keyword: OECD Model

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Alternatives to In Vivo Draize Rabbit Eye and Skin Irritation Tests with a Focus on 3D Reconstructed Human Cornea-Like Epithelium and Epidermis Models

  • Lee, Miri;Hwang, Jee-Hyun;Lim, Kyung-Min
    • Toxicological Research
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    • v.33 no.3
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    • pp.191-203
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    • 2017
  • Human eyes and skin are frequently exposed to chemicals accidentally or on purpose due to their external location. Therefore, chemicals are required to undergo the evaluation of the ocular and dermal irritancy for their safe handling and use before release into the market. Draize rabbit eye and skin irritation test developed in 1944, has been a gold standard test which was enlisted as OECD TG 404 and OECD TG 405 but it has been criticized with respect to animal welfare due to invasive and cruel procedure. To replace it, diverse alternatives have been developed: (i) For Draize eye irritation test, organotypic assay, in vitro cytotoxicity-based method, in chemico tests, in silico prediction model, and 3D reconstructed human cornealike epithelium (RhCE); (ii) For Draize skin irritation test, in vitro cytotoxicity-based cell model, and 3D reconstructed human epidermis models (RhE). Of these, RhCE and RhE models are getting spotlight as a promising alternative with a wide applicability domain covering cosmetics and personal care products. In this review, we overviewed the current alternatives to Draize test with a focus on 3D human epithelium models to provide an insight into advancing and widening their utility.

Workers' Compensation Insurance and Occupational Injuries

  • Shin, Il-Soon;Oh, Jun-Byoung;Yi, Kwan-Hyung
    • Safety and Health at Work
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    • v.2 no.2
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    • pp.148-157
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    • 2011
  • Objectives: Although compensation for occupational injuries and diseases is guaranteed in almost all nations, countries vary greatly with respect to how they organize workers' compensation systems. In this paper, we focus on three aspects of workers' compensation insurance in Organization for Economic Cooperation and Development (OECD) countries - types of systems, employers' funding mechanisms, and coverage for injured workers - and their impacts on the actual frequencies of occupational injuries and diseases. Methods: We estimated a panel data fixed effect model with cross-country OECD and International Labor Organization data. We controlled for country fixed effects, relevant aggregate variables, and dummy variables representing the occupational accidents data source. Results: First, the use of a private insurance system is found to lower the occupational accidents. Second, the use of risk-based pricing for the payment of employer raises the occupational injuries and diseases. Finally, the wider the coverage of injured workers is, the less frequent the workplace accidents are. Conclusion: Private insurance system, fixed flat rate employers' funding mechanism, and higher coverage of compensation scheme are significantly and positively correlated with lower level of occupational accidents compared with the public insurance system, risk-based funding system, and lower coverage of compensation scheme.

A Study on Determinants of Photovoltaic Energy Growth: Panel Data Regression with Autoregressive Disturbance (태양광 보급의 결정요인 연구: 자기상관 패널데이터 분석)

  • Kim, Kwangsu;Choi, Jinsoo;Yoon, Yongbeum;Park, Soojin
    • Current Photovoltaic Research
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    • v.10 no.1
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    • pp.6-15
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    • 2022
  • Climate change is among the most important issues facing mankind in modern society. However, global PV energy expansion has been driven mainly by OECD countries. We investigate the determinants of PV energy growth by panel data of selected OECD countries from 1991 to 2018. We investigate four categories of driving factors: socioeconomic, technological, country specific, and policy factors. The test results support that PV capacity growth is significantly driven by technology development and multidimensional environment policy factors. Socioeconomic factors such as CO2, GDP, and electricity price are statistically significant on the growth of PV energy, too. Whereas, country-specific solar potential factor is the least related. As most of the socioeconomic factors are exogenous, we need to focus more on PV technology development and policy measures.

NUCLEAR DATA UNCERTAINTY PROPAGATION FOR A TYPICAL PWR FUEL ASSEMBLY WITH BURNUP

  • Rochman, D.;Sciolla, C.M.
    • Nuclear Engineering and Technology
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    • v.46 no.3
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    • pp.353-362
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    • 2014
  • The effects of nuclear data uncertainties are studied on a typical PWR fuel assembly model in the framework of the OECD Nuclear Energy Agency UAM (Uncertainty Analysis in Modeling) expert working group. The "Fast Total Monte Carlo" method is applied on a model for the Monte Carlo transport and burnup code SERPENT. Uncertainties on $k_{\infty}$, reaction rates, two-group cross sections, inventory and local pin power density during burnup are obtained, due to transport cross sections for the actinides and fission products, fission yields and thermal scattering data.

Is Fertility Rate Proportional to the Quality of Life? An Exploratory Analysis of the Relationship between Better Life Index (BLI) and Fertility Rate in OECD Countries (출산율은 삶의 질과 비례하는가? OECD 국가의 삶의 질 요인과 출산율의 관계에 관한 추이분석)

  • Kim, KyungHee;Ryu, SeoungHo;Chung, HeeTae;Gim, HyeYeong;Park, HeongJoon
    • International Area Studies Review
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    • v.22 no.1
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    • pp.215-235
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    • 2018
  • Policy concerns related to raising fertility rates are not only common interests among the OECD countries, but they are also issues of great concern to South Korea whose fertility rate is the lowest in the world. The fertility rate in South Korea continues to decline, even though most of the national budget has been spent on measures to address this and many studies have been conducted on the increase in the fertility rates. In this regard, this study aims to verify the effectiveness of the detailed factors affecting the fertility rate that have been discussed in the previous studies on fertility rates, and to investigate the overall trend toward enhancing the quality of life and increasing the fertility rate through macroscopic and structural studies under the recognition of problems related to the policy approaches through the case studies of the European countries. Toward this end, this study investigated if a high quality of life in advanced countries contributes to the increase in the fertility rate, which country serves as a state model that has a high quality of life and a high fertility rate, and what kind of social and policy environment does the country have with regard to childbirth. The analysis of the OECD Better Life Index (BLI) and CIA fertility rate data showed that the countries whose people enjoy a high quality of life do not necessarily have high fertility rates. In addition, under the recognition that a country with a high quality of life and a high birth rate serves as a state model that South Korea should aim for, the social characteristics of Iceland, Ireland, and New Zealand, which turned out to have both a high quality of life and a high fertility rate, were compared with those of Germany, which showed a high quality of life but a low fertility rate. According to the comparison results, the three countries that were mentioned showed higher awareness of gender equality; therefore, the gender wage gap was small. It was also confirmed that the governments of these countries support various policies that promote both parents sharing the care of their children. In Germany, on the other hand, the gender wage gap was large and the fertility rate was low. In a related move, however, the German government has made active efforts to a paradigm shift toward gender equality. The fertility rate increases when the synergy lies in the relationship between parents and children; therefore, awareness about gender equality should be firmly established both at home and in the labor market. For this reason, the government is required to provide support for the childbirth and rearing environment through appropriate family policies, and exert greater efforts to enhance the effectiveness of the relevant systems rather than simply promoting a system construction. Furthermore, it is necessary to help people in making their own childbearing decisions during the process of creating a better society by changing the national goal from 'raising the fertility rate' to 'creating a healthy society made of happy families'

Proposed TATI Model for Predicting the Traffic Accident Severity (교통사고 심각 정도 예측을 위한 TATI 모델 제안)

  • Choo, Min-Ji;Park, So-Hyun;Park, Young-Ho
    • KIPS Transactions on Software and Data Engineering
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    • v.10 no.8
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    • pp.301-310
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    • 2021
  • The TATI model is a Traffic Accident Text to RGB Image model, which is a methodology proposed in this paper for predicting the severity of traffic accidents. Traffic fatalities are decreasing every year, but they are among the low in the OECD members. Many studies have been conducted to reduce the death rate of traffic accidents, and among them, studies have been steadily conducted to reduce the incidence and mortality rate by predicting the severity of traffic accidents. In this regard, research has recently been active to predict the severity of traffic accidents by utilizing statistical models and deep learning models. In this paper, traffic accident dataset is converted to color images to predict the severity of traffic accidents, and this is done via CNN models. For performance comparison, we experiment that train the same data and compare the prediction results with the proposed model and other models. Through 10 experiments, we compare the accuracy and error range of four deep learning models. Experimental results show that the accuracy of the proposed model was the highest at 0.85, and the second lowest error range at 0.03 was shown to confirm the superiority of the performance.

A Study on Impact of Factors Influencing Maritime Freight Rates Using Poisson and Negative Binomial Regression Analysis on Blank Sailings of Shipping Companies (포아송 및 음이항 회귀분석을 이용한 해상운임 결정요인이 해운선사의 블랭크 세일링에 미치는 영향 분석 연구)

  • Won-Hyeong Ryu;Hyung-Sik Nam
    • Journal of Navigation and Port Research
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    • v.48 no.1
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    • pp.62-77
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    • 2024
  • In the maritime shipping industry, imbalance between supply and demand has persistently increased, leading to the utilization of blank sailings by major shipping companies worldwide as a key means of flexibly adjusting vessel capacity in response to shipping market conditions. Traditionally, blank sailings have been frequently implemented around the Chinese New Year period. However, due to unique circumstances such as the global pandemic starting in 2020 and trade tensions between the United States and China, shipping companies have recently conducted larger-scale blank sailings compared to the past. As blank sailings directly impact freight transport delays, they can have negative repercussions from perspectives of both businesses and consumers. Therefore, this study employed Poisson regression models and negative binomial regression models to analyze the influence of maritime freight rate determinants on shipping companies' decisions regarding blank sailings, aiming to proactively address potential consequences. Results of the analysis indicated that, in Poisson regression analysis for 2M, significant variables included global container shipping volume, container vessel capacity, container ship scrapping volume, container ship newbuilding index, and OECD inflation. In negative binomial regression analysis, ocean alliance showed significance with global container shipping volume and container ship order volume, the alliance with container ship capacity and interest rates, non-alliance with international oil prices, global supply chain pressure index, container ship capacity, OECD inflation, and total alliance with container ship capacity and interest rates.

An exploratory study on the impacts of International Digital Tax Agreement on Korean Industry (디지털세 국제 합의가 국내 산업에 미치는 영향에 대한 탐색적 연구)

  • Lee, Jinhui;Kim, Taeyeol
    • Journal of Platform Technology
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    • v.9 no.4
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    • pp.10-31
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    • 2021
  • The digital tax, recently referred to as the Google tax was finally agreed at the 31st General Assembly of the OECD (October 8, 2021) with full support by 136 countries and will take effect from 2023. The purpose of this study is to analyze the digital tax prepared by the OECD for global MNEs, and to suggest the impacts on the Korean industry and to present the Korean governmental countermeasures. As the first study, we analyzed the international agreement on digital tax. In results, we found that even if global MNEs do not set up a business operation in overseas countries, if sales and profits are generated, 25% of the excess profit is borne as tax (pillar 1), and when MNEs do business in all the countries, they are liable to at least a 15% tax (pillar 2). We think that countries around the world have prepared a minimum countermeasure to protect their companies in anticipation that global MNEs will easily encroach on their markets in the future. As the second study, in order to discover the reason why the MNEs are so strong, we investigated the trends of Google and B2B SaaS companies in details. In results, we discovered that the global MNEs establishes a digital platform partnership ecosystem that enables them to enter foreign markets easily and expand rapidly. In conclusion, as a countermeasure for the Republic of Korea, governmental policies were proposed at the corporate (startup nurturing), industry, and national level respectively.

Fitting competing risks models using medical big data from tuberculosis patients (전국 결핵 신환자 의료빅데이터를 이용한 경쟁위험모형 적합)

  • Kim, Gyeong Dae;Noh, Maeng Seok;Kim, Chang Hoon;Ha, Il Do
    • The Korean Journal of Applied Statistics
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    • v.31 no.4
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    • pp.529-538
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    • 2018
  • Tuberculosis causes high morbidity and mortality. However, Korea still has the highest tuberculosis (TB) incidence and mortality among OECD countries despite decreasing incidence and mortality due to the development of modern medicine. Korea has now implemented various policy projects to prevent and control tuberculosis. This study analyzes the effects of public-private mix (PPM) tuberculosis control program on treatment outcomes and identifies the factors that affecting the success of TB treatment. We analyzed 130,000 new tuberculosis patient cohort from 2012 to 2015 using data of tuberculosis patient reports managed by the Disease Control Headquarters. A cumulative incidence function (CIF) compared the cumulative treatment success rates for each factor. We compared the results of the analysis using two popular types of competition risk models (cause-specific Cox's proportional hazards model and subdistribution hazard model) that account for the main event of interest (treatment success) and competing events (death).

Development of Competency-Based Entrepreneurship Education Model : The Case of K University (역량기반 기업가정신 교육모델 개발 : K대학의 사례)

  • Lee, Cheolki;Ahn, Taeuk;Lee, Sangkon;Lee, Sangsook
    • Journal of Practical Engineering Education
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    • v.12 no.1
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    • pp.61-72
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    • 2020
  • Entrepreneurship works as a driving force in socio-economic innovation, the leading role in job creation and economic development. As the importance of entrepreneurship is increased, research on entrepreneurship training methods based on the capability model is vitalized in order to effectively develop entrepreneurship in the EU and OECD. In Korea, however, the research on entrepreneurship capability is nearly not proceeding while the outcome of entrepreneurship training is insufficient. The research, therefore, invented the entrepreneurship training model at K university after analyzing cases of entrepreneurship training from inside and outside of the country followed up through the theoretical consideration of entrepreneurship capability and collecting suggestions from experts. The training model rejects the existing economics-based theory education, focuses on the development of entrepreneurship capability, and suggests an educational process considering students' developing stage of entrepreneurship capabilities.