• 한국식품영양과학회지
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• 제27권1호
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• pp.191-199
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• 1998

This paper has studied the nutritional iron status of adults in the city of Taegu. The subjects of the experiment were twenty six men and women living in the city of Taegu. The iron intake was 26.1mg for men and 17.1mg for women, which were respectively 217.5% and 95% of RDA. For men heme iron was 5% and nonheme iron, 95% for women heme iron was 5.8% and nonheme iron, 94.2%. The absorption rate of dietary iron was 6.2% for men and 9.1% for women. The hemoglobin was 14.5g/dl for men and 11.9g/dl for women, and the rate of developing anemia was 8.3% in men and 57.1% in women. The serum ferritin was 57.8ng/ml with men, which was found to be normal, and 14.7ng/ml with women, which showed that 57.1% of women were in the condition of iron depletion or iron deficiency anemia. The rate of developing anemia resulting from the deficiency of serum ferritin was as high as that from the deficiency of hemoglobin. The correlation between iron intake based on the dietary record, and energy intake, vegetable protein intake and dietary fiber intake was found to be positive. So was the correlation between the iron intake, and hemoglobin, serum ferritin and urinary iron excretion. There was also a positive correlation between hemoglobin, and hematocrit and serum ferritin. The correlation between fecal iron excretion and serum ferritin was positive. Fecal iron excretion and urinary iron excretion can be complemented by iron intake but the fact should be considered that 95% of iron intake is nonheme iron, which is difficult to absorb. Based on the above-mentioned things, serum ferritin and hemoglobin can be used as the standards of measuring anemia. As women in their child bearing years show the high rate of 57.1% of developing anemia, the more thorough nutritional education of iron is required.

• 생태와환경
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• 제39권4호통권118호
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• pp.445-449
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• 2006

Phenolic compounds are manufacturing by-products commonly found in industrial wastewater. The toxicity of high level phenolic compounds in wastewater threatens not only the aquatic organisms, but also many components of the adjacent ecosystem. One of the major light harvesting pigments in cyanobacteria is phycocyanin which can be rapidly and specifically degraded by external stimuli such as nutritional depletion or environmental stress. We employed the cyanobacterium Anabaena sp. PCC 7120 as an indicator organism in estimating the pollution level by phenolic compounds. The phycocyanin content of the cyanobacterium decreased without significantly altering the total chlorophyll as the phenol concentration in a medium increased. We examined the phenol contamination level using the correlation of the phycocyanin content and the phenol concentration. Our results indicated that no significant pollution by phenolic compounds was found in several waterbodies in the vicinity of Daegu, South Korea.

• Tuberculosis and Respiratory Diseases
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• 제44권1호
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• pp.93-103
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• 1997

연구배경 : 만성 폐쇄성 폐질환 환자에서 영양결핍이 흔히 나타나며, 그 원인기전은 섭취의 부족보다는 호흡근의 열량요구량의 증가에 따른 과신진대사로 인하여 상대적인 결핍이 초래되기 때문으로 알려져 있다. 또한 만성 패쇄성 폐질환에서 영양결핍은 폐기능, 근력 및 운동수행능 등의 생리적 척도와도 유의한 상관관계를 보이며, 나아가서는 예후에도 영향을 미치는 독립적인 인자로 보고된 바 있다. 방법 : 만성 폐쇄성 폐질환 환자와 유사연령의 건강한 대조군에서 영양섭취량을 조사하였고, 신체계측과 혈액검사 등의 영양상태의 지표를 평가하였으며, 영양상태의 평가지표들과 만성 폐쇄성 폐질환의 중요한 폐기능지표인 1초간 노력성 호기량과의 상관성을 조사하였다. 결과 : 1) 대상 환자는 남자 25예였으며, 평균연령은 66.1세였고, 1초간 노력성 호기량의 예측치에 대한 비율은 $42{\pm}14%$였다. 대조군은 폐기능이 정상인 건강한 남자 26예였고, 평균연령은 65.0세였다. 2) 1일 열량섭취량/열량요구량 비율은 환자군에서 $107{\pm}28%$, 대조군에서 $94{\pm}14%$로 환자군에서 높은 경향을 보였다(p=0.06). 3) 환자군과 대조군의 비만도가 92.8% 및 101.6%로(p=0.024), 신체비만지수가 $20.0kg/m^2$ 및 $21.9kg/m^2$ 로(p=0.015), 악력이 29.0kg 및 34.3kg으로(p=0.003), 환자군에서 유의하게 낮았으나, 상완삼두근부위 피부두겹두께, 상완위 근육둘레, 알부민 및 총림프구수는 두 군간에 유의한 차이가 없었다. 환자군에서 저체중군의 비율은 40%(10/25)였고, 대조군에서는 15%(4/26)였다. 4) 비만도, 신체비만지수, 상완삼두근부위 피부두겹두께, 상완위 근육둘레 등은 1초간 노력성 호기량과 유의한 상관성이 있었다. 결론 : 이상의 결과에서 만성 패쇄성 폐질환 환자는 저체중과 말초근력의 저하 등 영양결핍의 소견을 보이나, 그 원인이 섭취량은 부족에 기인하지 않음을 알 수 있었으며, 영양상태 평가의 지표들이 1초간 노력성 호기량과 유의하게 상관됨을 알 수 있었다.

• 대한지역사회영양학회지
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• 제3권4호
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• pp.556-564
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• 1998

The purpose of this study was to assess the iron nutritional status of college women residing in the Kyungin area. The anthropometric parameters, nutrient intake, and biochemical status of iron were measured for 102 college women. The mean height and weight were 160.3cm and 52.4kg, respectively. The proportion of subjects whose BMI was less than 20 was 41.3%. The proportion of subjects assessed as overweight(25$\geq$25%) assessed by the fat percent(FP) was 53.9%. The mean daily intake of iron was 13.90mg(77.1% of RDA), composed of 0.97mg of heme iron and 12.44mg(69.0% of RDA). When the sources of iron were grouped as rice(including bread), noodle, soup, side dish, and snack, noodle provided, 3.95mg of iron regarded as the highest amount. Subjects were taking 6.72mg(51.4% of RDA) of iron per day from main dishes(rice, bread and noodle). The fifty five percent of the subjects showed iron depletion(serum femitin<20ng/ml)and 33.4% showed suppressed erythropoiesis with iron deficiency(serum ferritin<10ng/ml). The anemic subjects assessed with transferrin saturation (<15%) represented 33.3% of the test population, whereas 11.8% of the subjects possessed less than 12g/dl of hemoglobin. Subjects not satisfied with their body shape were having significantly lower amount of energy intake(p<0.05) than the subjects satisfied with their body shape. College women having mothers who graduated from university had a significantly decreased amount of energy, carbohydrates, fat and vitamin C(p<0.05). The mean RBC and serum iron of the subjects who were on a diet more than one month were lower than those of the subjects who were not on a diet(p<0.05).

• Journal of Nutrition and Health
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• 제38권7호
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• pp.495-502
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• 2005

This study was performed to investigate effects of dietary folic acid supplementation on plasma homocysteine levels, thiobarbituric acid reactive substance s (TBARS) level s and liver SAM/SAH ratio in hyperhomocysteinaemia-induced pregnant rats. Forty-two female Sprague-Dawley rats were divided three groups (C: control diet, HFD: $0.3\%$ homocystine and 0 mg folic acid diet, HFS: $0.3\%$ homocystine and 8 mg/kg folic acid diet) according to homocystine and folic acid levels in the diet. They were fed experimental diets for 5 weeks prior to the mating and also during the entire period of pregnancy till gestational day 20. Dietary folic acid supplementation caused a significant decrease in plasma homocysteine levels which had been increased by a homocystine-diet, with a concomitant increase in plasma and liver folate levels. Liver TBARS levels in homocysteine-folic acid-deficient group (HFD) were higher than those in control group. Dietary folic acid supplementation increased hepatic SAM/SAM ratio in homocysteine-folic acid- sopplemetantion group (HFS) when compared to the HFD (p < 0.05). These data suggest that folate depletion and elevated plasma homocysteine may promote oxidative stress in rat livers and influence the remethylation cycle of the homocysteine metabolism detrimentally. In conclusion, dietary folic acid supplementation was found to be effective for lowering plasma homocysteine levels, relieving oxidative stress, and improving the methylation status in the body.

• Tuberculosis and Respiratory Diseases
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• 제52권4호
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• pp.346-354
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• 2002

연구배경: 만성폐쇄성질환은 호흡곤란과 신체활동능력저하가 특징이며, 이들 환자의 체중감소는 예후를 결정하는 중요한 인자로 알려져 있다. 이러한 사실은 체성분의 변화가 환자의 운동능력에 영향을 미칠 수 있는 요인으로 작용할수 있음을 의미한다. 저자들은 최대산소섭취량에 영향을 미치는 요소들을 분석하여, 체성분의 변화가 환자의 최대운동능력에 미치는 영향을 알아보았다. 대상 및 방법: 만성폐쇄성질환으로 입원한 83명(남자 63명, 여자 20명)을 대상으로 급성기 증상이 호전된 후 퇴원하기 직전 안정시 폐기능 및 체성분 분석, 그리고 운동부하심폐기능을 측정하여 최대산소섭취량에 영향을 미치는 요소를 분석하였다. 결 과: 만성폐쇄성질환자의 최대산소섭취량은 영양상태와 관계없이 감소하였으나, 영양결핍환자들의 최대산소섭취량 및 최대운동부하량, 그리고 최대산소맥압은 영양상태가 정상인 환자보다 훨씬 낮았다. 최대산소섭취량은 최대흡기압 (r=0.71), 최대호기압(r=0.68), 노력성 흡기폐활량(r=0.55), 그리고 폐확산능(r=0.53)과 상관관계가 있고(p<0.01), 체성분 가운데 제지방량(r=0.55), 체질량지수(r=0.47), 제지방지수(r=0.41)와 상관관계가 있었다(p<0.01). 최대산소섭취량과 상관관계가 있는 지표들을 단계적 회귀분석으로 확인한 결과 제지방량 (t=2.31, p<0.05), 노력성 흡입폐활량(t=3.22, p<0.01), 폐확산능(t=3.41, p<0.01)이 유의수준 5% 이내에서 통계적인 의미가 있었다. 이들 세 가지 지표만으로 회귀모델을 만들 경우 최대산소섭취량의 68.8%를 설명할 수 있었다($r^2=0.688$, p<0.05). 결 론: 만성폐쇄성폐질환자의 제지방량은 안정시 폐기능과 더불어 최대운동능력에 영향을 미치는 중요한 인자이며, 환자의 활동능력을 유지하기 위하여 근육량을 보존할 수 있는 치료적인 접근이 반드시 필요할 것으로 생각한다.

• Journal of Chest Surgery
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• 제53권3호
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• pp.93-103
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• 2020

Background: Risk assessment for pulmonary resection in patients with early-stage non-small-cell lung cancer (NSCLC) is important for minimizing postoperative morbidity. Depletion of skeletal muscle mass is closely associated with impaired nutritional status and limited physical ability. We evaluated the relationship between skeletal muscle depletion and early postoperative complications in patients with early-stage NSCLC. Methods: Patients who underwent curative lung resection between 2016 and 2018 and who were diagnosed with pathological stage I/II NSCLC were included, and their records were retrospectively analyzed. The psoas volume index (PVI, ㎤/㎥) was calculated based on computed tomography images from routine preoperative positron emission tomography-computed tomography. Early postoperative complications, defined as those occurring within 90 days of surgery, were compared between the lowest sex-specific quartile for PVI and the remaining quartiles. Results: A strong correlation was found between the volume and the cross-sectional area of the psoas muscle (R²=0.816). The overall rate of complications was 57.6% among patients with a low PVI and 32.8% among those with a normal-to-high PVI. The most common complication was prolonged air leak (low PVI, 16.9%; normal-to-high PVI, 9.6%), followed by pneumonia (low PVI, 13.6%; normal-to-high PVI, 7.9%) and recurrent pleural effusion (low PVI, 11.9%; normal-to-high PVI, 6.8%). The predictors of overall complications were low PVI (odds ratio [OR], 2.18; 95% confidence interval [CI], 1.07-4.09; p=0.03), low hemoglobin level (OR, 0.686; 95% CI, 0.54-0.87; p=0.002), and smoking history (OR, 3.93; 95% CI, 2.03-7.58; p<0.001). Conclusion: Low PVI was associated with a higher rate of early postoperative complications in patients with early-stage NSCLC.

• 대한지역사회영양학회지
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• 제5권3호
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• pp.493-501
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• 2000

The purpose of this study was to assess the nutritional status of iron of the elderly residing in the Jeonju area. The anthropometric parameters, nutrient intake and biochemical status of iron, were measured for 60 korean elderly(23 elderly men and 37 elderly women aged 60 - 79 years old). The level of hemoglobin(Hb), hematocrint(Hct), serum iron(Fe), total iron binding capacity(TIBC) and serum ferritin(Ferritin) were measured and transferrin saturation(TFsaturation) was calculated. Mean values of Hb, Hct, Fe, TIBC, TFsaturation and Ferritin were 14.49$\pm$0.93g/이, 42.47$\pm$2.59%, 125.48$\pm$52,.46$\mu\textrm{g}$/dl, 338.13$\pm$45.92$\mu\textrm{g}$/dl, 193.00$\pm$125.03$\mu\textrm{g}$/l in elderly men and 12.82$\pm$0.99$\mu\textrm{g}$/dl, 37.66$\pm$2.90%, 100.08$\pm$42.82$\mu\textrm{g}$/dl, 356.41$\pm$54.65$\mu\textrm{g}$/dl, and 99.35$\pm$117.22$\mu\textrm{g}$/l in elderly women, respectively. Prevalence of iron deficiency varied greatly with biochemical indices of iron. It was 13.0% when judged by Fe(60 $\mu\textrm{g}$/dl) and TFsaturation(15%) whereas 34.78% by Hct(41%) in elderly men. However 13.5% of the elderly women showed iron depletion(Ferritin<20$\mu\textrm{g}$/l) and 43.2% showed suppressed erythropoiesis with iron deficiency(TIBC>360$\mu\textrm{g}$/dl). The anemic subjects assessed with TFsaturation(<15%) represented 13.5% of the elderly women, whereas 18.9% of the subjects possessed less than 12g/dl of Hb. The Hb concentration was positively correlated with Hct(r=0.980, p<0.001), Fe(r=0.384, p<0.01) and TFsaturation(r=0.349, p<0.01). On the other hand, Ferritin concentration showed a significantly negative correlation with TIBC(r=0.349, p<0.05) and a positive correlation with TFsaturation(r=0.362, p<0.01). Major food groups of iron intake in the elderly were vegetables, cereals, and fish. The mean daily intake of iron was not significantly different between elderly men and women(12.82mg vs 10.35mg). Intake of heme iron however, was significantly higher(p<0.01) in elderly men(1.03mg) than women(0.42mg). Total absorbable iron caculated by the method of Monsen was 0.55mg, 0.40mg in elderly men and women, respectively and bioavailability of dietary iron 4.29% and 3.87%.

• 한국수산과학회지
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• 제27권6호
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• pp.839-846
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• 1994

Changing concepts in fishery science increasingly are recognizing depletion of traditional stocks, utilization of alternate(non-traditional) species, demand for high quality products, and a total resource utilization approach. Innovative practices are occurring in fisheries processing wherein solid and liquid discharges are no longer treated as 'waste,' but rather as valuable feedstocks for recovery of a variety of value-added ('value enhanced') by-products. Among these are protein hydrolysates, soluble proteins and amino acids, proteolytic enzymes, flavor and flavor extracts, pigments, and biopolymers such as chitosan. Properties and applications of this deacetylated derivative of chitin are noted. Crustacean processing by-products are discussed in terms of their serving as materials for generation of natural flavors and flavor extracts, and products such as fish sauces using contemporary enzymatic techniques. Various food and feed applications of fisheries processing by-products are illustrated with increased usage seen in formulated diets for an expanding aquaculture market. Examples are given of aquaculture becoming increasingly significant in global fisheries resource projections. Critical issues in the international seafood industry Include those of seafood quality, processing quality assurance (HACCP), and recognition of the nutritional and health-related properties of fisheries products. A variety of current seafood processing research is discussed, including that of alternate fish species for surimi manufacture and formulation of value-added seafood products from crawfish and blue crab processing operations. Increasing emphasis is being placed on international aspects of global fisheries and the role of aquaculture in such considerations. Coupled with the need for the aquatic food industry to develop innovative seafood products for the 21st century is that of total resource utilization. Contemporary approaches in seafood processing recognize the need to discard the traditional concept of processing 'waste' and adapt a more realistic, and economically sound, approach of usable by-products for food and feed application. For example, in a period of declining natural fishery resources it is no longer feasible to discard fish frames following fillet removal when a significant amount of residual valuable flesh is present that can be readily recovered and properly utilized in a variety of mince-based formulated seafood products.

• Childhood Kidney Diseases
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• 제10권1호
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• pp.58-64
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• 2006

최근 들어 모유 단독 수유의 장기화 및 잘못된 식이 제한 등으로 인한 비타민 D 결핍성 구루병의 발병이 점차 증가하고 있는 시점에서, 비타민 D 결핍성 구루병 및 이와 동반된 저칼슘혈증성 경련에 대한 예는 다소 보고된 바 있으나, 비타민 D 결핍으로 인해 골 병변 뿐 아니라 저칼슘 혈증, 부갑상선 기능 항진증, 나아가 신세뇨관성 산증까지 초래한 예는 보고된 바가 없었다. 저자들은 8개월간 모유 단독 수유만 유지하던 중 저칼슘혈증성 경련을 주소로 내원하여 골 병변을 동반한 비타민 D 결핍성 구루병과 부갑상선 항진 및 근위 세뇨관성 산증을 진단 받은 후, 적절한 칼슘, 비타민 D, 중탄산염 투여 후 완전히 회복된 환자의 1례를 경험하였기에 보고하는 바이다.