• 제목/요약/키워드: Nutraceutical food

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Isolation and Characterization of Steroids of Nutraceutical Value in Physalis minima

  • Misra Laxmi N.;Lal Pyare;Kumar Devinder
    • Preventive Nutrition and Food Science
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    • 제11권2호
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    • pp.133-139
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    • 2006
  • There is great demand of nutraceutical secondary metabolites in the world so as to feed the population by improving agricultural production with new varieties of food crops but what is still more important is to add nutrition into the food. Physalis minima, plant of Solanaceae family, contain certain secondary metabolites which enhance the over all metabolic functions of the body. Withasteroids are one of such phytochemicals that are generally regarded as safe. These chemicals are almost monopoly of the plants of Solanaceae. The leaves, stem and roots of P. minima have been examined to yield several steroids, identification of which has been discussed in this paper. These withasteroids contribute to the potential nutraceutical and health function value since incorporation of withanolides in the diet may prevent or decrease the growth of tumors in humans.

함양에서 재배된 여주의 추출조건에 따른 생리활성 (Comparison of Biological Activities of Ethanol Extracts of Unripe Fruit of Bitter Melon (Momordica charantia L.) Cultivated in Hamyang, Korea)

  • 문정한;최동원;김성은;서문지훈;홍수영;김현규;조계만;송진;강상수;김강화;권오경
    • 한국식품영양과학회지
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    • 제44권11호
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    • pp.1637-1644
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    • 2015
  • 본 연구에서는 항당뇨 소재로 잘 알려져 있는 여주를 이용한 혈당 개선 건강기능성 원료 개발의 기초 연구로 주정 추출조건에 따른 항산화, 항당뇨, 항비만 효능을 검증하였다. 여주주정 추출물의 총 폴리페놀과 총 플라보노이드 함량, 항산화능, 탄수화물과 지방의 흡수 지연능을 평가하는 ${\alpha}$-glucosidase 및 pancreatic lipase 저해 활성은 온도 $70^{\circ}C$, 주정농도 70% 추출조건에서 가장 높게 나타났다. 본 연구 결과를 바탕으로 향후 여주의 항산화, 항당뇨, 항비만 효능 등 대사성 질환에 대한 예방 및 개선 효과를 가지는 건강기능식품을 개발하는 데 기초자료로 활용될 것으로 기대된다.

Nutraceutical Properties of Dioscorea opposita Thunb. (Yam) Fermented by Lactobacillus bulgaricus and Streptococcus thermophilus

  • Jeon, Byung Ju;Ko, Eun Jung;Kwak, Hae-Soo
    • Journal of Dairy Science and Biotechnology
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    • 제30권2호
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    • pp.69-74
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    • 2012
  • This study was performed to determine by the ability of the mixed culture of Lactobacillus bulgaricus and Streptococcus thermophilus to ferment Dioscorea opposita Thunb. (yam) and to evaluate the nutraceutical value of fermented yam. The titratable acidity (TA) value increased from 2 to 6% with increased concentrations in both raw yam and extracted lactic acid bacteria (LAB) fermented yam (LFY). The viable cell counts and the allantoin and diosgenin contents were higher in raw LFY at large concentrations (6%) than in extracted LFY samples at all fermentation periods up to 32 h. Based on these data, it confirmed that raw yam fermented by the combination culture of L. bulgaricus and S. thermophilus for various fermentation periods favors the symbiotic growth of LAB and results in higher nutraceutical content.

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Nelumbo nucifera Leaf Extract Regulates Lipid Metabolism and Differentiation in 3T3-L1 Adipocytes and db/db Mice

  • Chul-Min Park;Oh Jin Min;Min-Seok Kim;Bhesh Raj Sharma;Dong Wook Kim;Dong Young Rhyu
    • Natural Product Sciences
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    • 제28권4호
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    • pp.161-167
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    • 2022
  • Obesity is a complex metabolic disorder that increases the risk for type 2 diabetes, hyperlipidemia, hypertension, and atherosclerosis. In this study, we evaluated the anti-obesity effects of Nelumbo nucifera leaf (NL) extract in 3T3-L1 adipocytes and obese db/db mice. NL extract among various parts (leaf, seed, and root) of N. nucifera most effectively reduced adipogenesis via inhibiting CCAAT enhancer binding protein α (C/EBPα) and peroxisome proliferator activated receptor γ (PPARγ) expression in 3T3-L1 adipocytes. The addition of NL extract enhanced the protein expression of uncoupling protein 2 (UCP2) as compared to untreated 3T3-L1 adipocytes. The oral administration of NL extract (100 mg/kg BW) significantly reduced food efficacy ratio, body weight, and face or total cholesterol level in obese db /db mice. Also, administration of NL extract significantly decreased adipocyte size and C/EBPα or PPARγ expression in the adipose tissues as compared with control (obese db/db mice). Therefore, our results suggest that NL extract among various parts of N. nucifera could be used as a functional food ingredient for the prevention and treatment of metabolic diseases including obesity and diabetes.

구절초의 추출조건에 따른 Linarin 함량과 In Vitro 생리활성 변화 (Comparison of Linarin Content and Biological Activity in Ethanol Extraction of Chrysanthemum zawadskii)

  • 김양지;김성은;이학성;홍수영;김성은;김영준;이진협;박성진;김준호;박윤제;김현규
    • 한국식품영양과학회지
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    • 제45권10호
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    • pp.1414-1421
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    • 2016
  • 본 연구에서는 구절초를 대상으로 물과 에탄올을 이용하여 확보한 각각의 추출물에 대하여 추출 수율, 폴리페놀 함량, 플라보노이드 함량, linarin 함량, ABTS 라디칼 소거능과 DPPH 라디칼 소거능, ${\alpha}$-glucosidase 저해 활성, lipase 저해 활성을 측정하였다. 구절초는 $70^{\circ}C$, 50% 주정 추출조건에서 추출 수율과 총플라보노이드 함량, linarin 함량, ABTS 라디칼 소거능과 DPPH 라디칼 소거능, ${\alpha}$-glucosidase 저해 활성, lipase 저해 활성이 가장 높았다. 또한, linarin 함량이 구절초 추출물의 생리활성과 상관관계가 있음을 확인하였다. 구절초 추출물은 linarin 함량이 증가함에 따라 항산화, 탄수화물 및 지방 흡수 지연 활성을 가지는 것으로 생각한다. 본 연구를 통하여 구절초의 추출조건에 따른 생리활성을 확인함으로써 향후 구절초를 이용한 건강기능식품의 소재 등으로 이용 가능할 것으로 생각한다.

Papaya: A gifted nutraceutical plant - a critical review of recent human health research

  • Karunamoorthi, Kaliyaperumal;Kim, Hyung-Min;Jegajeevanram, Kaliyaperumal;Xavier, Jerome;Vijayalakshmi, Jayaraman
    • 셀메드
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    • 제4권1호
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    • pp.2.1-2.17
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    • 2014
  • The plant kingdom is considered to be a repository of modern medicine, attributable to their rich source of bio-active molecules and secondary metabolites. It is indeed the Nutraceuticals that enhance immunity and ensure a healthier life because of their prophylactic and therapeutic values. Over centuries, papaya [Caricaceae; (Carica papaya Linn.)] is a renowned nutritious and medicinal plant. Each part of the papaya like root, stem, leaf, flower, fruit, seed, rinds, and latex has its own nutraceutical properties. It serves as food, cooking aid, and Ethnomedicine to prevent and treat wide-range of diseases and disorders. It has also been traditionally used as appetite enhancer, meat tenderizer, purgative, medicinal acne, abortifacient and vermifuge. Over decades, a series of scientific attempts were made to authenticate the nutraceutical properties of papaya. These studies validated that the papaya has antiplasmodial, antitrichochramal, antitrichomonal, antidengue, and anti-cancer activities. They have also exhibited that papaya possesses antiseptic, antiparasitic, anti-inflammatory, antidiabetic, and contraceptive features, and it helps in the management of sickle-cell anaemia, HIV, heart diseases and digestional disorders too. Nevertheless, the responsible bio-active molecules and their mode of actions remain indistinct and imprecise, and this calls for further pharmacological and clinical research on them. Conclusively, papaya is one of the naturally gifted plants; though its nutraceutical properties as a food or as a quasi-drug are poorly understood or undervalued by people. Accordingly, this scrutiny, demand for instigation of public health awareness campaigns to promote papaya consumption, so that the society shall acquire optimal benefits of papaya and in turn prevent and alleviate various diseases and illness.

Components of Nutraceutical Value in Physalis minima

  • Misra, L.N.;Lal, P.;Kumar, D.
    • Preventive Nutrition and Food Science
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    • 제11권1호
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    • pp.25-30
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    • 2006
  • It is of utmost importance to feed the current world population by improving agricultural production with newer varieties of food crops, but what is still more important is to add nutrition into the food. Some of the plants, which are currently growing in the wastelands, contain certain phytochemicals which add to their neutraceutical and health value. These plants contain secondary metabolites which enhance the over all metabolic functions of the body. Withasteroids are one of such phytochemicals. These chemicals are almost exclusively found in plants of the Solanaceae family; one of which, Physalis minima, contains several with asteroids. The aerial parts and roots of P. minima have been found to contain several steroids, identification of which is been discussed in this paper. These with asteroids contribute to the functional value since incorporation of withanolides in the diet may prevent or decrease the growth of tumors in humans.

Preparation and Characterization of Resveratrol Nanoemulsions Stabilized by Self-assembly and Complex Coacervation Consisting of Sodium Alginate, Chitosan, and β-Cyclodextrin

  • Choi, Ae-Jin;Jo, Younghee;Cho, Yong-Jin;Kim, Tae-Eun;Kim, Chong-Tai
    • 산업식품공학
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    • 제21권3호
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    • pp.215-224
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    • 2017
  • Resveratrol was incorporated into various combinations of single- and double-layer nanoemulsions, prepared by self-assembly emulsification and complex coacervation with chitosan, alginate, and ${\beta}$-cyclodextrin, respectively. Resveratrol nanoemulsions were composed of medium-chain trigacylglycerols (MCTs), $Tween^{(R)}$ 80, water, chitosan, alginate, and ${\beta}$-cyclodextrin. The corresponding mixtures were formulated for the purpose of being used as a nutraceutical delivery system. Resveratrol nanoemulsions were obtained with particle sizes of 10-800 nm, with the size variation dependent on the emulsification parameters including the ratio of aqueous phase and surfactant ratio. Resveratrol nanoemulsions were characterized by evaluating particle size, zeta-potential value, stability, and release rate. There were no significant changes in particle size and zeta-potential value of resveratrol nanoemulsions during storage for 28 days at $25^{\circ}C$. The stability of resveratrol in the double-layer nanoemulsions complexed with chitosan or ${\beta}$-cyclodextrin was higher, compared with the single-layer nanoemulsions.