• Structural Engineering and Mechanics
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• 제86권5호
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• pp.607-619
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• 2023

This study, it was tried to evaluate the asphalt behavior under tensile loading conditions through indirect Brazilian and direct tensile tests, experimentally and numerically. This paper is important from two points of view. The first one, a new test method was developed for the determination of the direct tensile strength of asphalt and its difference was obtained from the indirect test method. The second one, the effects of particle size and loading rate have been cleared on the tensile fracture mechanism. The experimental direct tensile strength of the asphalt specimens was measured in the laboratory using the compression-to-tensile load converting (CTLC) device. Some special types of asphalt specimens were prepared in the form of slabs with a central hole. The CTLC device is then equipped with this specimen and placed in the universal testing machine. Then, the direct tensile strength of asphalt specimens with different sizes of ingredients can be measured at different loading rates in the laboratory. The particle flow code (PFC) was used to numerically simulate the direct tensile strength test of asphalt samples. This numerical modeling technique is based on the versatile discrete element method (DEM). Three different particle diameters were chosen and were tested under three different loading rates. The results show that when the loading rate was 0.016 mm/sec, two tensile cracks were initiated from the left and right of the hole and propagated perpendicular to the loading axis till coalescence to the model boundary. When the loading rate was 0.032 mm/sec, two tensile cracks were initiated from the left and right of the hole and propagated perpendicular to the loading axis. The branching occurs in these cracks. This shows that the crack propagation is under quasi-static conditions. When the loading rate was 0.064 mm/sec, mixed tensile and shear cracks were initiated below the loading walls and branching occurred in these cracks. This shows that the crack propagation is under dynamic conditions. The loading rate increases and the tensile strength increases. Because all defects mobilized under a low loading rate and this led to decreasing the tensile strength. The experimental results for the direct tensile strengths of asphalt specimens of different ingredients were in good accordance with their corresponding results approximated by DEM software.

• 한국수산과학회지
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• 제27권4호
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• pp.413-433
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• 1994

진해만은 빈산소로 인한 수산생물의 생산성 저하가 현저하다. 본 연구에서는 진해만의 수질환경개선 및 회복을 위해서 빈산소 수괴의 형성방지가 무엇보다도 중요하다고 생각되어 해수유동 및 물질순환 모델을 이용하여 빈산소 수괴 형성상태를 재현하였고, 주요 오염부하가 용존산소에 미치는 영향의 정도를 예측하여 어장환경 관리방안을 도출한 결과는 다음과 같다. 저층의 용존산소 농도분포는 수온 및 밀도성층과 밀접한 관계를 가지고 변동하였고 수온성층이 가장 강했던 $6{\sim}7$월에 양식어장이 밀집된 진해만 서부해역과 마산만 해역에서 2.0mg/l이하의 빈산소 수괴가 형성되었다. 해수유동 모델에 의한 $M_2$분조 계산결과 창조시 유향의 주류는 가덕수로를 통하여 서쪽으로 이동하였고 일부는 마산만으로 유입되었으며, 낙조시는 반대방향이었다. 최강유속은 가덕수로 부근에서 발생하였고 진동만, 고현성만, 원문만등의 진해만 서부해역과 마산만에서는 5cm/sec이하로 미약하였다. 항유는 만 중앙부와 칠천도 사이에서 반시계방향의 환유가 형성되는 것이 특징적이었으며, 마산만이나 당황만 입구 부근에서는 표층의 경우 남향의 흐름이 나타났고, 저층에서는 북향의 흐름이 형성 되었다. 물질순환 모델의 보정결과 상관성은 0.85이상을 보였고 상대오차는 $28\%$이하의 범위내에서 여름철의 빈산소 수괴를 재현하였다. 각종 오염부하가 용존산소에 미치는 영향의 정도와 범위를 시뮬레이션을 통하여 예측한 결과 SOD가 전지역에 걸쳐 가장 큰 영향을 나타내었고 ,마산만의 유입부하도 용존산소 분포에 큰 영향을 미쳤으나 마산만내 국한되어 나타났으며, 양식생물에 의한 부하는 영향도 적었고 진해만 서부해역에 국한되었다. 빈산소 수괴가 강하게 형성되는 마산만과 진해만 서부해역의 빈산소 수괴 형성방지를 위해 효율적인 오염저감 대책으로서 마산만의 경우 유입 COD부하와 SOD를 저감해야하며, 진해만 서부해역의 경우 SOD가 주가 되어야 함을 알 수 있었다. 회복시켜야 할 용존산소 농도를 해역II등급인 5.0mg/l의 농도를 유지시키기 위해서는 마산만의 경우 유입되는 COD 부하를 $50\%$, SOD를 $70\%$로 저감해야 하며, 진해만 서부해역의 경우 SOD를 $95\%$, 양식생물 오염부하를 $90\%$까지 저감해야 되는 것으로 나타났다.

• 대한토목학회논문집
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• 제5권1호
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• pp.21-30
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• 1985

Tension Leg Platform (TLP)이란 평행위치로부터 일정 범위내에서 움직임으로 인하여 외 력의 효과를 완화시키는 compliant 구조물인 동시에, 기인장력을 받고 있는 연직 anchor cable 이 있으므로 부력이 자중을 초과하게 되는 안정한 platform 이다. 일반적으로 부체는 해상조건이 험할수록, 그리고 수심이 깊어질수록 동요가 심해지는데 TLP는 기인장 cable로 인하여 심해에서도 비교적 동요가 작아서 최근 대수심구조물의 총아로 각광받고 있다. 일찌기 Paulling 등이 TLP 거동의 예측을 위하여 수정된 Morison 방정식을 사용하는 선형동유체력합성방법을 발표하였다. 그러나 만일 TLP의 각 부재가 Morison 방정식의 가정이 성립할 수 없을 정도로 크다면 새로운 해석이 필요하다 하겠다. 일본의 Tanaka는 이런 경우에 McCamy-Fuchs 이론의 결과치를 이용하였으나, 완전한 해석이라기 보다는 일종의 간편법이라 하겠다. 본고에서는 큰 배수용적을 가진 연직부체가 있고, 이론적 해석의 결과를 검토해 볼 수 있는 수리모형 실험 결과가 있는 Deep Oil Technology (DOT) 회사의 TLP를 대상으로 하였다. 이 TLP는 부력을 전담하고 있는 연직축대칭 원통과 이들을 연결하고 있는 세부재로 이루어져 있어 축대칭부분에는 축대칭 Green 함수를 사용하여 동유체력을 구하고 세부재는 종래의 수정된 Morison 방정식의 항력항을 선형화하여 동유체력을 구하였다. 그리하여 부재의 각 미소부분에서 구한 힘들을 TLP의 중심에 원점을 둔 좌표계로 옮겨 동적응답을 구한 것이다. 본 해석에서 부재 상호간의 작용은 무시하였으며 단지 부재간의 거리효과만 고려하였다. 따라서 사용된 좌표계는 전체 (Global) 좌표계, 지점 (Local) 좌표계 및 파랑 (Wave) 좌표계 등이었고 각 좌표계간의 변환식이 필요하였다. 전체적인 해석정도는 선형이론으므로 케이블의 강성도 역시 선형적으로 구하였으며, 앞서 언급했다시피 Morison 방정식의 비선형항인 항력항은 Fourier 해석으로 선형화 하였다. 이러한 Fourier 해석은 잘 알려져 있는 Lorentz 원리와 같다고 볼 수 있다. 세부재의 경우 접선력은 무시하였고 수입자의 운동에 의한 부채에 대한 수직력만 고려하였다. 여기서 파랑좌표계에서 지점좌표계로의 좌표변환이 주의를 요하고 있다. 이제 이렇게 구한 각 힘들을 전체좌표 계에서 6개의 자유도별로 운동방정식에 대입하면 각 자유도별 동적응답이 구하여지는 것이다. DOT TLP의 Surge mode에 대한 동적응답을 실험치와 비교하여 본 결과, 세부재에 대한 고려를 뺄 수 없음을 알 수 있었다. 이는 연직축대칭 부체의 크기가 그리 크지 않으므로 인한 것이며, TLP의 원형의 경우에는 보다 더 관성력이 지배적일 것으로 사료된다.

• 설비공학논문집
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• 제25권6호
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• pp.346-361
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• 2013

This article reviews the papers published in the Korean Journal of Air-Conditioning and Refrigeration Engineering during 2012. It is intended to understand the status of current research in the areas of heating, cooling, ventilation, sanitation, and indoor environments of buildings and plant facilities. The conclusions are as follows : (1) The research works on thermal and fluid engineering have been reviewed as groups of fluid machinery, pipes and valves, fuel cells and power plants, ground-coupled heat pumps, and general heat and mass transfer systems. Research issues are mainly focused on new and renewable energy systems, such as fuel cells, ocean thermal energy conversion power plants, and ground-coupled heat pump systems. (2) Research works on the heat transfer area have been reviewed in the categories of heat transfer characteristics, pool boiling and condensing heat transfer, and industrial heat exchangers. Researches on heat transfer characteristics included the results for natural convection in a square enclosure with two hot circular cylinders, non-uniform grooved tube considering tube expansion, single-tube annular baffle system, broadcasting LED light with ion wind generator, mechanical property and microstructure of SA213 P92 boiler pipe steel, and flat plate using multiple tripping wires. In the area of pool boiling and condensing heat transfer, researches on the design of a micro-channel heat exchanger for a heat pump, numerical simulation of a heat pump evaporator considering the pressure drop in the distributor and capillary tubes, critical heat flux on a thermoexcel-E enhanced surface, and the performance of a fin-and-tube condenser with non-uniform air distribution and different tube types were actively carried out. In the area of industrial heat exchangers, researches on a plate heat exchanger type dehumidifier, fin-tube heat exchanger, an electric circuit transient analogy model in a vertical closed loop ground heat exchanger, heat transfer characteristics of a double skin window for plant factory, a regenerative heat exchanger depending on its porous structure, and various types of plate heat exchangers were performed. (3) In the field of refrigeration, various studies were executed to improve refrigeration system performance, and to evaluate the applicability of alternative refrigerants and new components. Various topics were presented in the area of refrigeration cycle. Research issues mainly focused on the enhancement of the system performance. In the alternative refrigerant area, studies on CO2, R32/R152a mixture, and R1234yf were performed. Studies on the design and performance analysis of various compressors and evaporator were executed. (4) In building mechanical system research fields, twenty-nine studies were conducted to achieve effective design of mechanical systems, and also to maximize the energy efficiency of buildings. The topics of the studies included heating and cooling, HVAC system, ventilation, renewable energy systems, and lighting systems in buildings. New designs and performance tests using numerical methods and experiments provide useful information and key data, which can improve the energy efficiency of buildings. (5) In the fields of the architectural environment, studies for various purposes, such as indoor environment, building energy, and renewable energy were performed. In particular, building energy-related researches and renewable energy systems have been mainly studied, reflecting interests in global climate change, and efforts to reduce building energy consumption by government and architectural specialists. In addition, many researches have been conducted regarding indoor environments.

• 한국해양학회지:바다
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• 제29권2호
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• pp.77-100
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• 2024

진해·마산만에 대한 연구는 그동안 해수순환, 조석, 조류, 적조, 수질, 빈산소 환경을 주제로 많이 연구되었으나 주로 단기간 동안 일어나는 해양현상에 대해 연구가 수행되었으며, 만 전체적인 해수순환을 일으키는 물리적 기작을 자세히 살펴본 연구는 부족했다. 오염 물질의 이동과 확산 같은 현상은 주로 계절별로 변동성이 크기 때문에, 이 연구에서는 진해·마산만 해역의 해수순환이 계절적으로 어떻게 변동하는지를 파악하고자 하였다. 이를 위하여 3차원 해양 순환 모델을 이용하여 2016년부터 2018년까지 진해·마산만의 해수순환을 수치모의하고, 여름철과 겨울철 해수순환을 표층, 중층, 저층에 대하여 살펴보았다. 또한 조석, 바람, 담수 유입에 대한 민감도 실험을 수행하여 각 요인들이 해수 유동에 미치는 영향을 분석하였다. 진해·마산만의 해수순환은 가덕수도 저층에서 대한해협의 해수가 유입되고, 표층에서 진해·마산만의 해수가 유출되는 대류성 염하구 순환이 일어난다. 가덕수도를 통해 교환되는 해수의 순환은 크게 진해만 동부해역과 진해만 서부해역으로 나누어져 일어난다. 각 해역의 수로 방향을 기준으로 해수 수송량을 계산하였을 때, 진해만 동부해역의 남북방향 해수 교환 수송량은 진해만 서부해역에서 일어나는 동서방향 해수 교환량보다 겨울철에는 2.3배, 여름철에는 1.4배 크다. 진해만 서부해역은 계절별로 작용하는 힘들의 균형이 변화하여 해수순환 특성이 계절에 따라 크게 다르다. 겨울철에는 북서풍이 만드는 전단응력과 해수면 기울기의 영향으로 표층 해류가 남쪽으로, 저층 해류는 북쪽으로 흐르는 남북방향 대류성 순환이 강화된다. 반면, 남서풍이 부는 여름철에는 바람 응력에 의해 표층 해수가 동쪽으로 유출되고, 또한 남동쪽 해수면이 높아 북쪽 방향 순압성 압력경도력이 커져 동쪽 방향 유속이 강화된다. 저층에서는 밀도 구배가 커져 경압성 압력경도력이 남쪽으로 크게 작용하여 지형류 균형에 의해 가덕수도의 해수가 서쪽으로 강하게 유입하는 동서방향 대류성 순환이 겨울철보다 26% 강화된다. 진해만 서부의 대류성 순환은 겨울과 여름 모두 조류와 바람의 영향을 크게 받는다. 진해만 동부해역과 마산만에서는 모든 계절에 표층에서는 해수가 외해로 유출되고, 저층에서는 해수가 만 안쪽으로 유입되는 전형적인 염하구 순환을 보였다. 겨울철에는 바람과 담수유입이, 여름철에는 조류의 영향이 남북방향 염하구 순환 규모에 크게 기여하였다. 진해만 동부해역에는 지형의 영향을 받아 형성된 조석 잔차류도 뚜렷하다. 이 연구에서 제시한 진해·마산만의 계절별 해수순환 특성은 이 해역의 오염물질 확산, 여름철 빈산소수괴의 형성 기작 파악, 적조 생물의 유입과 유출을 이해하는 데 도움이 될 것으로 기대된다.

• 한국해양환경ㆍ에너지학회지
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• 제7권1호
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• pp.1-12
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• 2004

진해만 해역에 있어서 적조발생역과 물질집적공간을 진단하기 위해서 수치모델링에 의해 하계 적조가 발생했을 때 환경요인의 변통에 따른 $Cha-{alpha}$ 분포와 물리과정의 기여도를 평가하였다. 해수유동모델에 의한 표층 잔차류는 무풍시와 풍속 2 m/sec이하일 때 진해만 서부해역과 동부해역에서 각각 남향과 북향 하는 흐름이 상접하는 공간이 예측되었고, 풍속이 강해질 때는 유속도 강해지고 유향도 크게 달라지는 것으로 나타났다. 생태계모델에 의해 하계 $Cha-{alpha}$를 예측한 결과, 진동만과 가덕수로 북단의 인근 해역에서는 20 mg/㎥ 이상으로 매우 높았고, 서부해역에서도 대부분 10 mg/㎥이상으로 진해만은 전역에서 하계에는 적조발생 가능성이 매우 높은 것으로 예측되었다. 현 상황에서 $Cha-{alpha}$현존량에 대한 물리과정량을 평가한 결과, 동부해역의 가덕수로 북단과 칠천도 주변, 서부해역의 진동만 내측 그리고 가조도 서쪽지역에서 물리과정량이 (+)로 계산되어 물질의 집적이 일어날 가능성이 큰 공간으로 평가되었고, 마산만, 행암만, 진동만, 원문만 및 고현만 등에서는 물리과정량이 (-) 즉, 발산지역으로 나타나서 물리과정량 보다는 생물학적인 증식과정이 큰 기여를 하는 것으로 고려되었다. 모델링과 현장관측자료 분석결과, 진해만 해역에 있어서 적조의 초기발생역은 마산만과 행암만으로 나타났다. 풍속의 증가는 $Cha-{alpha}$의 농도를 감소시키지만 물리적으로 집적하는 공간의 확대를 야기 시키는 것으로 예측되었고, 동남풍 계열보다는 북서풍 계열이 더 큰 영향을 미치는 것으로 나타났다. 일사량 및 일조시간의 변통은 물리적 집적공간의 분포에는 큰 영향이 없었지만, $Cha-{alpha}$의 급격한 증감을 초래하는 것으로 시뮬레이션되었다. 육상오염부하량 자체만의 변동으로는 $Cha-{alpha}$를 적조발생 가능농도이하로 감소시키지는 않는 것으로 모델링되었다.

• 한국해양학회지:바다
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• 제24권2호
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• pp.351-373
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• 2019

인공위성이 관측한 해수면 높이 자료를 활용하여 울릉분지 일대에서 발생하는 냉수성 소용돌이들을 1993년부터 2015년까지 Winding-Angle 방법을 이용하여 탐지하고 분류하였다. 냉수성 소용돌이들 중에서 동한난류 사행의 첫 번째 골에서 형성되어 동쪽으로 흐르는 해류의 주경로로부터 남서쪽으로 떨어져 나온 독도 냉수성 소용돌이(Dokdo Cold Eddy, DCE)를 구분하였고, 그 이동 특성을 분석하였다. 또한 국립수산과학원(National Institute of Fisheries Science)이 관측한 수온과 염분 자료와 Hybrid Coordinate Ocean Model의 수치모의 결과를 이용하여 DCE 중심 근처에서 수온과 유속의 수직구조를 살펴보았다. DCE는 23년 동안 총 112개 발생하였고, 이 중 39개의 DCE가 서쪽으로 이동하여 한국 동해안 근처 연안에 도달하였으며, 평균 이동 거리는 250.9 km, 평균 수명은 93일, 평균 이동 속도는 3.5 cm/s였다. 나머지 73개의 DCE는 동쪽으로 이동하거나 생성된 위치 주변을 맴돌다가 소멸하였다. DCE 아래 50~100 m에서 수온(T)과 염분(S)이 주변보다 낮아(T < $5^{\circ}C$, S < 34.1) 등온선들과 등염선들이 돔(dome, 반구형으로 된 지붕 모양) 구조를 보였다. 또한 DCE의 중심에서 평균 38 km 떨어진 곳에서 10 cm/s 이상의 해류가 표층부터 수심 300 m까지 반시계방향으로 원을 그리며 흐른다. 동한난류가 이안하여 동쪽으로 흐르다가 울릉도 북쪽에서 울릉도를 끼고 시계방향으로 흘러서 사행을 시작하고, 울릉도 동쪽에 위치한 사행의 첫 번째 골이 남서쪽으로 깊이 파고들면, 해류사행의 마루와 마루가 연결되고 골 부분이 독립적으로 떨어져 나와 반시계방향 순환을 형성하면서 DCE가 생성된다. DCE가 서쪽으로 이동할 때 울릉 난수성 소용돌이(Ulleung Warm Eddy, UWE)의 가장자리를 따라 우회하여 시계방향으로 U 모양을 그리며 한국 동해안 쪽으로 이동한다. DCE가 연안 부근에 도달하면, 동한난류는 냉수성 소용돌이 보다 더 남쪽에서 이안하고, 냉수성 소용돌이의 가장자리를 따라 우회하여 북쪽으로 흐른다. 연안에서 독도 냉수성 소용돌이가 약화되고 약 30일 후에 소멸하면, 동한난류가 다시 한국 동해안을 따라 북쪽으로 흘러서 본래의 경로를 회복한다. DCE는 열과 염을 북쪽에서 남쪽으로 꾸준히 수송하고 울릉분지 남서쪽에 냉수해역 형성에 도움을 주며, 양의 상대와도를 가지고 와서 동한난류의 경로를 변경시키는 역할을 한다. 서쪽으로 이동하는 DCE 중에서 일부는 연안 냉수성 소용돌이와 병합되어 울릉분지 서쪽에 넓고 긴 냉수해역을 만들고 반시계 방향의 순환을 형성한다. 이와 같이 병합된 소용돌이는 북쪽에 UWE를 남쪽에 동한난류로부터 분리시킨다.

• 재무관리연구
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• 제6권1호
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• pp.31-62
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• 1989

본 연구에서는 변동환율을 취하고 있는 small open economy 가 대외경제에 얼마나 긴밀하게 연결되어 있는가에 따라 그 경제의 환율이 어떻게 달리 반응하는가를 살폈다. 그 경제주체들은 대단히 효율적으로 필요한 정보를 활용해서 미래를 예측한다. 즉 이성적 기대(rational erpectation)를 갖는다고 가정한다. Small open economy의 환율을 분석한 기존의 모델들 대부분이 어떤 특정한 국제경제여건에 국한하여서 가능하면 단순한 모델들을 설정했기 때문에 그 결론들이 얼마나 광범위하게 다른 경우에도 유효한지 쉽게 알 수가 없다. 본 연구에선 점차적으로 현실적인 요소들을 모델에 가미해가고, 현대의 고도정보처리능력에 가장 적합한 기대형태인 이성적 기대를 다룸으로써 변동환율의 움직임에 어떤 일반성이 있을 수 있는가를 공부했다. 구체적으로, 제2장에는 국내경제가 국제경제와 구매력동등가설 (purchasing power parity)과 이자율동등가성(uncovered interest parity)로 긴밀히 연결되어 있는 경우를 살피고, 제3장에는 구매력동등가설은 적용되지 않고 이자율동등가설만 국내경제에 유효한 경우를 살폈다. 2장과 3장에서 국내투자자가 투자할 수 있는 금융자산은 통화와 국내.외 채권이며 주식시장은 고려되지 않았다. 4장에서는 상당히 자립적이고 현실적인 요소가 많이 반영된 경제를 분석하였다. 즉 국내경제가 국제경제와 구매동등가설이나 이자율동등가설로 직접적으로 연결되지 아니한 상황에서 주식을 포함한 모든 금융자산이 투자대상자산으로 가능하고, 또 환율의 변동이 재화의 국내가격에 반영되는데 어느 정도의 시차가 요구되는 경우를 살펴 보았다. 여기서는 내재변수의 수가 많은 관계로 numerical simulation을 이용했다. 본 연구의 결론 일부로서 첫째, 자국경제의 통화가 팽창되는 경우, 그 경제의 국제경제유착 정도에 상관없이 자국통화의 평가절하를 곧 유발하였다. 재정팽창의 경우에는 통화팽창의 경우처럼 환율의 방향에 대한 일반적인 결론을 얻지 못 했다. 둘째, 환율의 움직임에 대해 최근의 자산가격 모델(asset model)들은 과러 전통적인 Keynesian모델들과는 다른 설명을 하고 있는데 본 연구에서는 단기적으로 금융시장에서 자산의 수급일치가 균형조건으로 고려되고, 장기적으로 는 경상수지일치가 균형조건으로 포함되었다. 그 결과 장기균형을 예측하는 경제주체들의 기대가 현재환율의 움직임에 큰 영향력을 미침으로써, 전통적인 Keynesian모델들의 단기예측 유효성을 무시할 수 없음을 보였다. 세째, 개방된 경제에서 변동환율의 초기과민반응(overshooting)이 그것이 미칠 수 있는 왜곡된 signal효과 등으로 인해 상당히 염려. 논의되고 있는데, 본 연구 4장의 경제는 상당히 자립적이고 자국통화로 표시된 채권이 국제적으로 수용되지 않음에도 불구하고, 경제주체들이 이성적기대를 견지하는 한, 환율의 초기과민반응은 쉽게 관찰될 수 있었다. 넷째, 환율의 변동이 재화의 국내통화가격에 반영되는데 시차를 인정한 경우, 경제주체들이 이성적기대를 갖는한, 시차도입 후 뚜렷이 다른 경제양상을 보이지 않았다.

• 대한의용생체공학회:의공학회지
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• 제6권2호
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• pp.1-8
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• 1985

The wall shear stress in the vicinity of end-to end anastomoses under steady flow conditions was measured using a flush-mounted hot-film anemometer(FMHFA) probe. The experimental measurements were in good agreement with numerical results except in flow with low Reynolds numbers. The wall shear stress increased proximal to the anastomosis in flow from the Penrose tubing (simulating an artery) to the PTFE: graft. In flow from the PTFE graft to the Penrose tubing, low wall shear stress was observed distal to the anastomosis. Abnormal distributions of wall shear stress in the vicinity of the anastomosis, resulting from the compliance mismatch between the graft and the host artery, might be an important factor of ANFH formation and the graft failure. The present study suggests a correlation between regions of the low wall shear stress and the development of anastomotic neointimal fibrous hyperplasia(ANPH) in end-to-end anastomoses. 30523 T00401030523 ^x Air pressure decay(APD) rate and ultrafiltration rate(UFR) tests were performed on new and saline rinsed dialyzers as well as those roused in patients several times. C-DAK 4000 (Cordis Dow) and CF IS-11 (Baxter Travenol) reused dialyzers obtained from the dialysis clinic were used in the present study. The new dialyzers exhibited a relatively flat APD, whereas saline rinsed and reused dialyzers showed considerable amount of decay. C-DAH dialyzers had a larger APD(11.70$\pm$1.32mmHg/min)compared to CF dialyzers(4.32$\pm$0.55mmHg/min)(p<0.05). However, there was no observable difference in the UFR between the two dialyzers. Neither APD nor UFR showed any significant increase with an increasing number of reuses for up to more than 20reuses. A substantial number of failures observed in APD(larger than 20mmHe/min)on the reused dialyzers(2 out of 40 CP and S out 26 C-DAK) were attributed to the Possible damage on the fibers. The CF 15-11 HFDs which failed APD test did not show changes in the UFR compared to normal dialyzers indicating that APD is a more sensitive test than UFR test to evaluate the integrity of the fibers. 30527 T00401030527 ^x For quantitative measurement of reflected light from a clinical diagnostic strip, a prototype old reflectance photometer was designed. The strip loader and cassette were made to obtain more accurate reflectance parameters. The strip was illuminated at 45˚c through optical fiber and the intensity of reflected light was determined at rectanguLat angle using a photodiode. The kubelka-munk coefficient and reflection optical density were determined ar four different wavelengths(500, 550, 570 and 610nm) for blood glucose strip. For higher concentration than 300mg/41 about glucose, a saturation state of abforbance was observed at 500, 550 and 570nm. The correlation between glucose concentration and parameters was the best at 610nm. 30535 T00401030535 ^x Radiation-induced fibrosarcoma tumors were grown on the flanks of C3H mice. The mice were divided into two groups. One group was injected with Photofrin II, intravenously (2.5mg/kg body weight). The other group received no Photofrin II. Mice from both groups were irradialed for approximately 15 minutes at 100, 300, or 500 mW/cm2 with the argon (488nm/514.5 nm), dye(628nm) and gold vapor (pulsed 628 nm) laser light. A photosensitizer behaved as an added absorber. Under our experimental conditions, the presence of Photolfrin II increased surface temperature by at least 40% and the temperature rise due to 300 mW/cm2 irradiation exceeded values for hyperthermia. Light and temperature distributions with depth were estimated by a computer model. The model demonstrated the influence of wavelength on the thermal process and proved to be a valuable tool to investigate internal temperature rise. 30536 T00401030536 ^x We investigated the structural geometry of thirty-eight Korean femurs. The purpose of this study is to identify major geometrical differences between Korean femurs 3nd others that we believe belong to Caucasians so that we would be able to get insights into the femoral component design that fits Asians including Koreans. We utilized computerized tomography (CT) images of femurs extracted from cadavers. The CT images were transformed into bitmap data by using a film scanner, and then analyzed by using a commercially available software called Image v.1.0 and a Macintosh IIci computer.The resulting data were compared with already published data. The major results show that the geometry of the Korean femurs is significantly different from that of Caucasians: (1) the anteversion angle and the canal flare index are greater by the amount of approximately 8˚ and 0.5, respectively, (2) the shape of the isthmus cross section is more round, and (3) the distance between the teaser trochanter and the proximal border of the isthmus is shelter by about 15 mm. The results suggested that the femoral component suitable for Asians should be different from the currently-used components designed and manufactured mostly by European or American companies. 30537 T00401030537 ^x It is well known that nonlinear propagation characteristics of the wave in the tissue may give very useful information for the medical diagnoisis. In this paper, a new method to detect nonlinear propagation characteristics of the internal vibration in the tissue for the low frequency mechanical vibration by using bispectral analysis is proposed. In the method, low frequency vibration of f0( = 100Hz) is applied on the surface of the object, and the waveform of the internal vibration x (t) is measured from Doppler frequency modulation of silmultaneously transmitted probing ultrasonic waves. Then, the bispectra of the signal x (t) at the frequencies (f0, f0) and (f0, 2f0) are calculated to estimate the nonlinear propagation characteristics as their magnitude ratio, w here since bispectrum is free from the gaussian additive noise we can get the value with high S/N. Basic experimental system is constructed by using 3.0 MHz probing ultrasonic waves and the several experiments are carried out for some phantoms. Results show the superiority of the proposed method to the conventional method using power spectrum and also its usefulness for the tissue characterization. 30541 T00401030541 ^x This paper describes the implementation of a computerized radial pulse diagnosis by aids of a clinical expert. On this base, we composed of the radial pulse diagnosis system in korean traditional medicine. The system composed of a radial pulse wave detection system and a radial pulse diagnosis system. With a detection system, we detected Inyoung and Cheongu radial pulse wave and processed it. Then, we have got the characteristic parameters of radial pulse wave and also quantified that according to the method of Inyoung-Cheongu Comparison Radial Pulse Diagnosis. We defined the jugement standard of radial pulse diagnosis system and then we confirmed the possibility for realization of automatic radial pulse diagnosis in korean traditional medicine. 30545 T00401030545 ^x Microspheres are expected to be applied to biomedical areas such as solid-phase immunoassays, drug delivery systems, immunomagnetic cell separation. To synthesize microspheres for biomedical application, "two stage shot growth method" was developed. The uniformity ratio of synthesized microspheres was always smaller than 1.05. And the surface charge density (or the number of ionizable functional groups) of the microspheres synthesized by "two stage shot growth method" was 6~13 times higher than that of the microspheres synthesized by conventional seeded batch copolymerization. As a previous step for biomedical application, adsorption experiments of bovine albumin on microspheres were carried out under various conditions. The maximum adsorbed amount was obtained in the neighborhood of pH 4.5. Isoelectric point of bovine albumin is pH 5.0, so experimental result shows that it shifted to acid area. The adsorption isotherm was obtained, the plateau region was always reached at 2.Og/L (bulk concentration of bovine albumin).The effect of the kind and the amount of surface functional group was also examined. 30575 T00401030575 ^x A medical image workstation was developed using multimedia technique. The system based on PC-486DX was designed to acquire medical images produced by medical imaging instruments and related audio information, that is, doctors' reporting results. Input information was processed and analyzed, then the results were presented in the form of graph and animation. All the informations of the system were hierarchically related with the image as the apex. Processing and analysis algorithms were implemented so that the diagnostic accuracy could be improved. The diagnosed information can be transferred for patient diagnosis through LAN(local area network). 30592 T00401030592 ^x In the conventional infrared imaging system, complex infrared lens systems are usually used for directing collimated narrow infrared beams into the high speed 2-dimensional optic scanner. In this paper, a simple reflective infrared optic system with a 2-dimensional optic scanner is proposed for the realization of medical infrared thermography system. It has been experimentally proven that the intfrared thermography system composed of the proposed optic system has the temperature resolution of 0.1˚c under the spatial resolution of lmrad, the image matrix size of 256 X 240, and tile imaging time of 4 seconds. 30593 T00401030593 ^x In this paper, MIIS (Medical Image Information System) has been designed and implemented using INGRES RDBMS, which is based on a client/server architecture. The implemented system allows users to register and retrieve patient information, medical images and diagnostic reports. It also provides the function to display these information on workstation windows simultaneously by using the designed menu-driven graphic user interface. The medical image compression/decompression techniques are implemented and integrated into the medical image database system for the efficient data storage and the fast access through the network. 30594 T00401030594 ^x In this paper, computerized BEAM was implemented for the space domain analysis of EEG. Trans-formation from temporal summation to two-dimensional mappings is formed by 4 nearest point inter-polaton method. Methods of representation of BEAM are two. One is dot density method which classify brain electrical potential 9 levels by dot density of gray levels and the other is colour method which classify brain electrical 12 levels by red-green colours. In this BEAM, instantaneous change and average energy distribution over any arbitrary time interval of brain electrical activity could be observed and analyzed easily. In the frequency domain, the distribution of energy spectrum of a special band can easily be distinguished normality and abnormality. 30608 T00401030608 ^x Laboratory information system (LIS) is a key tool to manage laboratory data in clinical pathology. Our department has developed an information system for routine hematology using down-sized computer system. We have used an IBM 486 compatible PC with 16MB main memory, 210 MB hard disk drive, 9 RS-232C port and 24 pin dot printer. The operating system and database management system were SCO UNIX and SCO foxbase, respectively. For program development, we used Xbase language provided by SCO foxbase. The C language was used for interface purpose. To make the system use friendly, pull-down menu was used. The system connected to our hospital information system via application program interface (API), so the information related to patient and request details is automatically transmitted to our computer. Our system interfaced with fwd complete blood count analyzers(Sysmex NE-8000 and Coulter STKS) for unidirectional data tansmission from analyzer to computer. The authors suggests that this system based on down-sized computer could provide a progressive approach to total LIS based on local area network, and the implemented system could serve as a model for other hospital's LIS for routine hematology. 30609 T00401030609 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed a composite that is consisted of calcium phosphate and collagen. To use as the structural matrix of the composite, collagen was purified from human umbilical cord. The obtained collagen was treated by pepsin to remove telopeptides, and finally, the immune-free atelocollagen was produced: The cross linked atelocollagen was highly resistant to the collagenase induced collagenolysis. The cross linked collagen demonstrated an improved tensile strength. 30618 T00401030618 ^x This paper is a study on the design of adptive filter for QRS complex detection. We propose a simple adaptive algorithm to increase capability of noise cancelation in QRS complex detection with two stage adaptive filter. At the first stage, background noise is removed and at the next stage, only spectrum of QRS complex components is passed. Two adaptive filters can afford to keep track of the changes of both noise and QRS complex. Each adaptive filter consists of prediction error filter and FIR filter The impulse response of FIR filter uses coefficients of prediction error filter. The detection rates for 105 and 108 of MIT/BIH data base were 99.3% and 97.4% respectively. 30619 T00401030619 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed and produced a composite that is consisted of calcium phosphate and collagen. Human umbilical cord origin pepsin treated type I atelocollagen was used as the structural matrix, by which sintered or non-sintered carbonate apatite was encapsulated to form an inorganic-organic composite. With cross linking atelocollagen by UV ray irradiation, the resistance to both compressive and tensile strength was increased. Collagen degradation by the collagenase induced collagenolysis was also decreased. 30620 T00401030620 ^x We have developed a monoleaflet polymer valve as an inexpensive and viable alternative, especially for short-term use in the ventricular assist device or total artificial heart. The frame and leaflet of the polymer valve were made from polyurethane, To evaluate the hemodynamic performance of the polymer valve a comparative study of flow dynamics past a polymer valve and a St. Jude Medical prosthetic valve under physiological pulsatile flow conditions in vitro was made. Comparisons between the valves were made on the transvalvular pressure drop, regurgitation volume and maximum valve opening area. The polymer valve showed smaller regurgitation volume and transvalvular pressure drop compared to the mechanical valve at higher heart rate. The results showed that the functional characteristics of the polymer valve compared favorably with those of the mechanical valve at higher heart rate. 30621 T00401030621 ^x Explosive evaporative removal process of biological tissue by absorption of a CW laser has been simulated by using gelatin and a multimode Nd:YAG laser. Because the point of maximun temperature of laser-irradiated gelatin exists below the surface due to surface cooling, evaporation at the boiling temperature is made explosively from below the surface. The important parameters of this process are the conduction loss to laser power absorption (defined as the conduction-to-laser power parameter, Nk), the convection heat transfer at the surface to conduction loss (defined as Bi), dimensionless extinction coefficient (defined as Br.), and dimensionless irradiation time (defined as Fo). Dependence of Fo on Nk and Bi has been observed by experiment, and the results have been compared with the numerical results obtained by solving a 2-dimensional conduction equation. Fo and explosion depth (from the surface to the point of maximun temperature) are increased when Nk and Bi are increased.To find out the minimum laser power for explosive evaporative removal process, steady state analysis has been also made. The limit of Nk to induce evaporative removal, which is proportional to the inverse of the laser power, has been obtained. 30622 T00401030622 ^x N1 and N2 gross neural action potentials were measured from the round window of the guinea pig cochlea at the onset of the acoustic stimuli. N1-N2 audiograms were made by means of regulating stimulant intensities in order to produce constant N1-N2 potentials as criteria for different input tone pip frequencies. The lowest threshold was measured with an input tone pip I5 dB SPL in intensity and 12 KHz in frequency when the animal was in normal physiological condition. The procedure of experimental measurements is explained in detail. This experimental approach is very useful for the investigation of the Cochlear function. Both noN1inear and active functions of the Cochlea can be monitored by N1-N2 audiograms. 30623 T00401030623 ^x In electrical impedance tomography(EIT), we use boundary current and voltage measurements toprovide the information about the cross-sectional distribution of electrical impedance or resistivity. One of the major problems in EIT has been the inaccessibility of internal voltage or current data in finding the internal impedance values. We propose a new image reconstruction method using internal current density data measured by NMR. We obtained a two-dimensional current density distribution within a phantom by processing the real and imaginary MR images from a 4.77 NMR machine. We implemented a resistivity mage reconstruction algorithm using the finite element method and sensitivity matrix. We presented computer simulation results of the mage reconstruction algorithm and furture direction of the research. 30624 T00401030624 ^x A new method of digital image analysis technique for discrimination of cancer cell was presented in this paper. The object image was the Thyroid eland cells image that was diagnosed as normal and abnormal (two types of abnormal: follicular neoplastic cell, and papillary neoplastic cell), respectively. By using the proposed region segmentation algorithm, the cells were segmented into nucleus. The 16 feature parameters were used to calculate the features of each nucleus. A9 a consequence of using dominant feature parameters method proposed in this paper, discrimination rate of 91.11% was obtained for Thyroid Gland cells. 30625 T00401030625 ^x An electrical stimulator was designed to induce locomotion for paraplegic patients caused by central nervous system injury. Optimal stimulus parameters, which can minimize muscle fatigue and can achieve effective muscle contraction were determined in slow and fast muscles in Sprague-Dawley rats. Stimulus patterns of our stimulator were designed to simulate electromyographic activity monitored during locomotion of normal subjects. Muscle types of the lower extremity were classified according to their mechanical property of contraction, which are slow muscle (msoleus m.) and fast muscle (medial gastrocneminus m., rectus femoris m., vastus lateralis m.). Optimal parameters of electrical stimulation for slow muscles were 20 Hz, 0.2 ms square pulse. For fast muscle, 40 Hz, 0.3 ms square pulse was optimal to produce repeated contraction. Higher stimulus intensity was required when synergistic muscles were stimulated simultaneously than when they were stimulated individually. Electrical stimulation for each muscle was designed to generate bipedal locomotion, so that individual muscles alternate contraction and relaxation to simulate stance and swing phases. Portable electrical stimulator with 16 channels built in microprocessor was constructed and applied to paraplegic patients due to lumbar cord injury. The electrical stimulator restored partially gait function in paraplegic patients. 30626 T00401030626 ^x Two-Dimensional modelling of the Cochlear biomechanics is presented in this paper. The Laplace partial differential equation which represents the fluid mechanics of the Cochlea has been transformed into two-dimensional electrical transmission line. The procedure of this transformation is explained in detail. The comparison between one and two dimensional models is also presented. This electrical modelling of the basilar membrane (BM) is clearly useful for the next approach to the further. Development of active elements which are essential in the producing of the sharp tuning of the BM. This paper shows that two-dimension model is qualitatively better than one-dimensional model both in amplitude and phase responses of the BM displacement. The present model is only for frequency response. However because the model is electrical, the two-dimensional transmission line model can be extended to time response without any difficult. 30627 T00401030627 ^x A method has been proposed for the fully automatic detection of left ventricular endocardial boundary in 2D short axis echocardiogram using geometric model. The procedure has the following three distinct stages. First, the initial center is estimated by the initial center estimation algorithm which is applied to decimated image. Second, the center estimation algorithm is applied to original image and then best-fit elliptic model estimation is processed. Third, best-fit boundary is detected by the cost function which is based on the best-fit elliptic model. The proposed method shows effective result without manual intervention by a human operator. 30628 T00401030628 ^x The intelligent trajectory control method that controls moving direction and average velocity for a prosthetic arm is proposed by pattern recognition and force estimations using EMG signals. Also, we propose the real time trajectory planning method which generates continuous accelleration paths using 3 stage linear filters to minimize the impact to human body induced by arm motions and to reduce the muscle fatigue. We use combination of MLP and fuzzy filter for pattern recognition to estimate the direction of a muscle and Hogan's method for the force estimation. EMG signals are acquired by using a amputation simulator and 2 dimensional joystick motion. The simulation results of proposed prosthetic arm control system using the EMf signals show that the arm is effectively followed the desired trajectory depended on estimated force and direction of muscle movements. 30638 T00401030638 ^x A new neural network architecture for the recognition of patterns from images is proposed, which is partially based on the results of physiological studies. The proposed network is composed of multi-layers and the nerve cells in each layer are connected by spatial filters which approximate receptive fields in optic nerve fields. In the proposed method, patterns recognition for complicated images is carried out using global features as well as local features such as lines and end-points. A new generating method of matched filers representing global features is proposed in this network. 30659 T00401030659 ^x An implementation scheme of the magnetic nerve stimulator using a switching mode power supply is proposed. By using a switching mode power supply rather than a conventional linear power supply for charging high voltage capacitors, the weight and size of the magnetic nerve stimulator can be considerably reduced. Maximum output voltage of the developed magnetic nerve stimulator using the switching mode power supply is 3, 000 volts and switching time is about 100 msec. Experimental results or human nerve stimulations using the developed stimulator are presented. 30768 T00401030768 ^x In this paper, we describe the design methodology and specifications of the developed module-based bedside monitors for patient monitoring. The bedside monitor consists of a main unit and module cases with various parameter modules. The main unit includes a 12.1" TFT color LCD, a main CPU board, and peripherals such as a module controller, Ethernet LAN card, video card, rotate/push button controller, etc. The main unit can connect at maximum three module cases each of which can accommodate up to 7 parameter modules. They include the modules for electrocardiograph, respiration, invasive blood pressure, noninvasive blood pressure, temperature, and SpO2 with Plethysmograph.SpO2 with Plethysmograph.

• 한국우주과학회:학술대회논문집(한국우주과학회보)
• /
• 한국우주과학회 1993년도 한국우주과학회보 제2권2호
• /
• pp.17-17
• /
• 1993

The wall shear stress in the vicinity of end-to end anastomoses under steady flow conditions was measured using a flush-mounted hot-film anemometer(FMHFA) probe. The experimental measurements were in good agreement with numerical results except in flow with low Reynolds numbers. The wall shear stress increased proximal to the anastomosis in flow from the Penrose tubing (simulating an artery) to the PTFE: graft. In flow from the PTFE graft to the Penrose tubing, low wall shear stress was observed distal to the anastomosis. Abnormal distributions of wall shear stress in the vicinity of the anastomosis, resulting from the compliance mismatch between the graft and the host artery, might be an important factor of ANFH formation and the graft failure. The present study suggests a correlation between regions of the low wall shear stress and the development of anastomotic neointimal fibrous hyperplasia(ANPH) in end-to-end anastomoses. 30523 T00401030523 ^x Air pressure decay(APD) rate and ultrafiltration rate(UFR) tests were performed on new and saline rinsed dialyzers as well as those roused in patients several times. C-DAK 4000 (Cordis Dow) and CF IS-11 (Baxter Travenol) reused dialyzers obtained from the dialysis clinic were used in the present study. The new dialyzers exhibited a relatively flat APD, whereas saline rinsed and reused dialyzers showed considerable amount of decay. C-DAH dialyzers had a larger APD(11.70${\pm}$1.32mmHg/min)compared to CF dialyzers(4.32${\pm}$0.55mmHg/min)(p<0.05). However, there was no observable difference in the UFR between the two dialyzers. Neither APD nor UFR showed any significant increase with an increasing number of reuses for up to more than 20reuses. A substantial number of failures observed in APD(larger than 20mmHe/min)on the reused dialyzers(2 out of 40 CP and S out 26 C-DAK) were attributed to the Possible damage on the fibers. The CF 15-11 HFDs which failed APD test did not show changes in the UFR compared to normal dialyzers indicating that APD is a more sensitive test than UFR test to evaluate the integrity of the fibers. 30527 T00401030527 ^x For quantitative measurement of reflected light from a clinical diagnostic strip, a prototype old reflectance photometer was designed. The strip loader and cassette were made to obtain more accurate reflectance parameters. The strip was illuminated at 45˚c through optical fiber and the intensity of reflected light was determined at rectanguLat angle using a photodiode. The kubelka-munk coefficient and reflection optical density were determined ar four different wavelengths(500,550,570 and 610nm) for blood glucose strip. For higher concentration than 300mg/41 about glucose, a saturation state of abforbance was observed at 500,550 and 570nm. The correlation between glucose concentration and parameters was the best at 610nm. 30535 T00401030535 ^x Radiation-induced fibrosarcoma tumors were grown on the flanks of C3H mice. The mice were divided into two groups. One group was injected with Photofrin II, intravenously (2.5mg/kg body weight). The other group received no Photofrin II. Mice from both groups were irradialed for approximately 15 minutes at 100,300, or 500 mW/cm2 with the argon (488nm/514.5 nm), dye(628nm) and gold vapor (pulsed 628 nm) laser light. A photosensitizer behaved as an added absorber. Under our experimental conditions, the presence of Photolfrin II increased surface temperature by at least 40% and the temperature rise due to 300 mW/cm2 irradiation exceeded values for hyperthermia. Light and temperature distributions with depth were estimated by a computer model. The model demonstrated the influence of wavelength on the thermal process and proved to be a valuable tool to investigate internal temperature rise. 30536 T00401030536 ^x We investigated the structural geometry of thirty-eight Korean femurs. The purpose of this study is to identify major geometrical differences between Korean femurs 3nd others that we believe belong to Caucasians so that we would be able to get insights into the femoral component design that fits Asians including Koreans. We utilized computerized tomography (CT) images of femurs extracted from cadavers. The CT images were transformed into bitmap data by using a film scanner, and then analyzed by using a commercially available software called Image v.1.0 and a Macintosh IIci computer.The resulting data were compared with already published data. The major results show that the geometry of the Korean femurs is significantly different from that of Caucasians: (1) the anteversion angle and the canal flare index are greater by the amount of approximately 8˚ and 0.5, respectively, (2) the shape of the isthmus cross section is more round, and (3) the distance between the teaser trochanter and the proximal border of the isthmus is shelter by about 15 mm. The results suggested that the femoral component suitable for Asians should be different from the currently-used components designed and manufactured mostly by European or American companies. 30537 T00401030537 ^x It is well known that nonlinear propagation characteristics of the wave in the tissue may give very useful information for the medical diagnoisis. In this paper, a new method to detect nonlinear propagation characteristics of the internal vibration in the tissue for the low frequency mechanical vibration by using bispectral analysis is proposed. In the method, low frequency vibration of f0( = 100Hz) is applied on the surface of the object, and the waveform of the internal vibration x (t) is measured from Doppler frequency modulation of silmultaneously transmitted probing ultrasonic waves. Then, the bispectra of the signal x (t) at the frequencies (f0, f0) and (f0, 2f0) are calculated to estimate the nonlinear propagation characteristics as their magnitude ratio, w here since bispectrum is free from the gaussian additive noise we can get the value with high S/N. Basic experimental system is constructed by using 3.0 MHz probing ultrasonic waves and the several experiments are carried out for some phantoms. Results show the superiority of the proposed method to the conventional method using power spectrum and also its usefulness for the tissue characterization. 30541 T00401030541 ^x This paper describes the implementation of a computerized radial pulse diagnosis by aids of a clinical expert. On this base, we composed of the radial pulse diagnosis system in korean traditional medicine. The system composed of a radial pulse wave detection system and a radial pulse diagnosis system. With a detection system, we detected Inyoung and Cheongu radial pulse wave and processed it. Then, we have got the characteristic parameters of radial pulse wave and also quantified that according to the method of Inyoung-Cheongu Comparison Radial Pulse Diagnosis. We defined the jugement standard of radial pulse diagnosis system and then we confirmed the possibility for realization of automatic radial pulse diagnosis in korean traditional medicine. 30545 T00401030545 ^x Microspheres are expected to be applied to biomedical areas such as solid-phase immunoassays, drug delivery systems, immunomagnetic cell separation. To synthesize microspheres for biomedical application, "two stage shot growth method" was developed. The uniformity ratio of synthesized microspheres was always smaller than 1.05. And the surface charge density (or the number of ionizable functional groups) of the microspheres synthesized by "two stage shot growth method" was 6~13 times higher than that of the microspheres synthesized by conventional seeded batch copolymerization. As a previous step for biomedical application, adsorption experiments of bovine albumin on microspheres were carried out under various conditions. The maximum adsorbed amount was obtained in the neighborhood of pH 4.5. Isoelectric point of bovine albumin is pH 5.0, so experimental result shows that it shifted to acid area. The adsorption isotherm was obtained, the plateau region was always reached at 2.Og/L (bulk concentration of bovine albumin).The effect of the kind and the amount of surface functional group was also examined. 30575 T00401030575 ^x A medical image workstation was developed using multimedia technique. The system based on PC-486DX was designed to acquire medical images produced by medical imaging instruments and related audio information, that is, doctors' reporting results. Input information was processed and analyzed, then the results were presented in the form of graph and animation. All the informations of the system were hierarchically related with the image as the apex. Processing and analysis algorithms were implemented so that the diagnostic accuracy could be improved. The diagnosed information can be transferred for patient diagnosis through LAN(local area network). 30592 T00401030592 ^x In the conventional infrared imaging system, complex infrared lens systems are usually used for directing collimated narrow infrared beams into the high speed 2-dimensional optic scanner. In this paper, a simple reflective infrared optic system with a 2-dimensional optic scanner is proposed for the realization of medical infrared thermography system. It has been experimentally proven that the intfrared thermography system composed of the proposed optic system has the temperature resolution of 0.1˚c under the spatial resolution of lmrad, the image matrix size of 256 X 240, and tile imaging time of 4 seconds. 30593 T00401030593 ^x In this paper, MIIS (Medical Image Information System) has been designed and implemented using INGRES RDBMS, which is based on a client/server architecture. The implemented system allows users to register and retrieve patient information, medical images and diagnostic reports. It also provides the function to display these information on workstation windows simultaneously by using the designed menu-driven graphic user interface. The medical image compression/decompression techniques are implemented and integrated into the medical image database system for the efficient data storage and the fast access through the network. 30594 T00401030594 ^x In this paper, computerized BEAM was implemented for the space domain analysis of EEG. Trans-formation from temporal summation to two-dimensional mappings is formed by 4 nearest point inter-polaton method. Methods of representation of BEAM are two. One is dot density method which classify brain electrical potential 9 levels by dot density of gray levels and the other is colour method which classify brain electrical 12 levels by red-green colours. In this BEAM, instantaneous change and average energy distribution over any arbitrary time interval of brain electrical activity could be observed and analyzed easily. In the frequency domain, the distribution of energy spectrum of a special band can easily be distinguished normality and abnormality. 30608 T00401030608 ^x Laboratory information system (LIS) is a key tool to manage laboratory data in clinical pathology. Our department has developed an information system for routine hematology using down-sized computer system. We have used an IBM 486 compatible PC with 16MB main memory, 210 MB hard disk drive, 9 RS-232C port and 24 pin dot printer. The operating system and database management system were SCO UNIX and SCO foxbase, respectively. For program development, we used Xbase language provided by SCO foxbase. The C language was used for interface purpose. To make the system use friendly, pull-down menu was used. The system connected to our hospital information system via application program interface (API), so the information related to patient and request details is automatically transmitted to our computer. Our system interfaced with fwd complete blood count analyzers(Sysmex NE-8000 and Coulter STKS) for unidirectional data tansmission from analyzer to computer. The authors suggests that this system based on down-sized computer could provide a progressive approach to total LIS based on local area network, and the implemented system could serve as a model for other hospital's LIS for routine hematology. 30609 T00401030609 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed a composite that is consisted of calcium phosphate and collagen. To use as the structural matrix of the composite, collagen was purified from human umbilical cord. The obtained collagen was treated by pepsin to remove telopeptides, and finally, the immune-free atelocollagen was produced: The cross linked atelocollagen was highly resistant to the collagenase induced collagenolysis. The cross linked collagen demonstrated an improved tensile strength. 30618 T00401030618 ^x This paper is a study on the design of adptive filter for QRS complex detection. We propose a simple adaptive algorithm to increase capability of noise cancelation in QRS complex detection with two stage adaptive filter. At the first stage, background noise is removed and at the next stage, only spectrum of QRS complex components is passed. Two adaptive filters can afford to keep track of the changes of both noise and QRS complex. Each adaptive filter consists of prediction error filter and FIR filter The impulse response of FIR filter uses coefficients of prediction error filter. The detection rates for 105 and 108 of MIT/BIH data base were 99.3% and 97.4% respectively. 30619 T00401030619 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed and produced a composite that is consisted of calcium phosphate and collagen. Human umbilical cord origin pepsin treated type I atelocollagen was used as the structural matrix, by which sintered or non-sintered carbonate apatite was encapsulated to form an inorganic-organic composite. With cross linking atelocollagen by UV ray irradiation, the resistance to both compressive and tensile strength was increased. Collagen degradation by the collagenase induced collagenolysis was also decreased. 30620 T00401030620 ^x We have developed a monoleaflet polymer valve as an inexpensive and viable alternative, especially for short-term use in the ventricular assist device or total artificial heart. The frame and leaflet of the polymer valve were made from polyurethane, To evaluate the hemodynamic performance of the polymer valve a comparative study of flow dynamics past a polymer valve and a St. Jude Medical prosthetic valve under physiological pulsatile flow conditions in vitro was made. Comparisons between the valves were made on the transvalvular pressure drop, regurgitation volume and maximum valve opening area. The polymer valve showed smaller regurgitation volume and transvalvular pressure drop compared to the mechanical valve at higher heart rate. The results showed that the functional characteristics of the polymer valve compared favorably with those of the mechanical valve at higher heart rate. 30621 T00401030621 ^x Explosive evaporative removal process of biological tissue by absorption of a CW laser has been simulated by using gelatin and a multimode Nd:YAG laser. Because the point of maximun temperature of laser-irradiated gelatin exists below the surface due to surface cooling, evaporation at the boiling temperature is made explosively from below the surface. The important parameters of this process are the conduction loss to laser power absorption (defined as the conduction-to-laser power parameter, Nk), the convection heat transfer at the surface to conduction loss (defined as Bi), dimensionless extinction coefficient (defined as Br.), and dimensionless irradiation time (defined as Fo). Dependence of Fo on Nk and Bi has been observed by experiment, and the results have been compared with the numerical results obtained by solving a 2-dimensional conduction equation. Fo and explosion depth (from the surface to the point of maximun temperature) are increased when Nk and Bi are increased.To find out the minimum laser power for explosive evaporative removal process, steady state analysis has been also made. The limit of Nk to induce evaporative removal, which is proportional to the inverse of the laser power, has been obtained. 30622 T00401030622 ^x N1 and N2 gross neural action potentials were measured from the round window of the guinea pig cochlea at the onset of the acoustic stimuli. N1-N2 audiograms were made by means of regulating stimulant intensities in order to produce constant N1-N2 potentials as criteria for different input tone pip frequencies. The lowest threshold was measured with an input tone pip I5 dB SPL in intensity and 12 KHz in frequency when the animal was in normal physiological condition. The procedure of experimental measurements is explained in detail. This experimental approach is very useful for the investigation of the Cochlear function. Both noN1inear and active functions of the Cochlea can be monitored by N1-N2 audiograms. 30623 T00401030623 ^x In electrical impedance tomography(EIT), we use boundary current and voltage measurements toprovide the information about the cross-sectional distribution of electrical impedance or resistivity. One of the major problems in EIT has been the inaccessibility of internal voltage or current data in finding the internal impedance values. We propose a new image reconstruction method using internal current density data measured by NMR. We obtained a two-dimensional current density distribution within a phantom by processing the real and imaginary MR images from a 4.77 NMR machine. We implemented a resistivity mage reconstruction algorithm using the finite element method and sensitivity matrix. We presented computer simulation results of the mage reconstruction algorithm and furture direction of the research. 30624 T00401030624 ^x A new method of digital image analysis technique for discrimination of cancer cell was presented in this paper. The object image was the Thyroid eland cells image that was diagnosed as normal and abnormal (two types of abnormal: follicular neoplastic cell, and papillary neoplastic cell), respectively. By using the proposed region segmentation algorithm, the cells were segmented into nucleus. The 16 feature parameters were used to calculate the features of each nucleus. A9 a consequence of using dominant feature parameters method proposed in this paper, discrimination rate of 91.11% was obtained for Thyroid Gland cells. 30625 T00401030625 ^x An electrical stimulator was designed to induce locomotion for paraplegic patients caused by central nervous system injury. Optimal stimulus parameters, which can minimize muscle fatigue and can achieve effective muscle contraction were determined in slow and fast muscles in Sprague-Dawley rats. Stimulus patterns of our stimulator were designed to simulate electromyographic activity monitored during locomotion of normal subjects. Muscle types of the lower extremity were classified according to their mechanical property of contraction, which are slow muscle (msoleus m.) and fast muscle (medial gastrocneminus m., rectus femoris m., vastus lateralis m.). Optimal parameters of electrical stimulation for slow muscles were 20 Hz, 0.2 ms square pulse. For fast muscle, 40 Hz, 0.3 ms square pulse was optimal to produce repeated contraction. Higher stimulus intensity was required when synergistic muscles were stimulated simultaneously than when they were stimulated individually. Electrical stimulation for each muscle was designed to generate bipedal locomotion, so that individual muscles alternate contraction and relaxation to simulate stance and swing phases. Portable electrical stimulator with 16 channels built in microprocessor was constructed and applied to paraplegic patients due to lumbar cord injury. The electrical stimulator restored partially gait function in paraplegic patients. 30626 T00401030626 ^x Two-Dimensional modelling of the Cochlear biomechanics is presented in this paper. The Laplace partial differential equation which represents the fluid mechanics of the Cochlea has been transformed into two-dimensional electrical transmission line. The procedure of this transformation is explained in detail. The comparison between one and two dimensional models is also presented. This electrical modelling of the basilar membrane (BM) is clearly useful for the next approach to the further. Development of active elements which are essential in the producing of the sharp tuning of the BM. This paper shows that two-dimension model is qualitatively better than one-dimensional model both in amplitude and phase responses of the BM displacement. The present model is only for frequency response. However because the model is electrical, the two-dimensional transmission line model can be extended to time response without any difficult. 30627 T00401030627 ^x A method has been proposed for the fully automatic detection of left ventricular endocardial boundary in 2D short axis echocardiogram using geometric model. The procedure has the following three distinct stages. First, the initial center is estimated by the initial center estimation algorithm which is applied to decimated image. Second, the center estimation algorithm is applied to original image and then best-fit elliptic model estimation is processed. Third, best-fit boundary is detected by the cost function which is based on the best-fit elliptic model. The proposed method shows effective result without manual intervention by a human operator. 30628 T00401030628 ^x The intelligent trajectory control method that controls moving direction and average velocity for a prosthetic arm is proposed by pattern recognition and force estimations using EMG signals. Also, we propose the real time trajectory planning method which generates continuous accelleration paths using 3 stage linear filters to minimize the impact to human body induced by arm motions and to reduce the muscle fatigue. We use combination of MLP and fuzzy filter for pattern recognition to estimate the direction of a muscle and Hogan's method for the force estimation. EMG signals are acquired by using a amputation simulator and 2 dimensional joystick motion. The simulation results of proposed prosthetic arm control system using the EMf signals show that the arm is effectively followed the desired trajectory depended on estimated force and direction of muscle movements. 30638 T00401030638 ^x A new neural network architecture for the recognition of patterns from images is proposed, which is partially based on the results of physiological studies. The proposed network is composed of multi-layers and the nerve cells in each layer are connected by spatial filters which approximate receptive fields in optic nerve fields. In the proposed method, patterns recognition for complicated images is carried out using global features as well as local features such as lines and end-points. A new generating method of matched filers representing global features is proposed in this network. 30659 T00401030659 ^x An implementation scheme of the magnetic nerve stimulator using a switching mode power supply is proposed. By using a switching mode power supply rather than a conventional linear power supply for charging high voltage capacitors, the weight and size of the magnetic nerve stimulator can be considerably reduced. Maximum output voltage of the developed magnetic nerve stimulator using the switching mode power supply is 3,000 volts and switching time is about 100 msec. Experimental results or human nerve stimulations using the developed stimulator are presented. 30768 T00401030768 ^x In this paper, we describe the design methodology and specifications of the developed module-based bedside monitors for patient monitoring. The bedside monitor consists of a main unit and module cases with various parameter modules. The main unit includes a 12.1" TFT color LCD, a main CPU board, and peripherals such as a module controller, Ethernet LAN card, video card, rotate/push button controller, etc. The main unit can connect at maximum three module cases each of which can accommodate up to 7 parameter modules. They include the modules for electrocardiograph, respiration, invasive blood pressure, noninvasive blood pressure, temperature, and SpO2 with Plethysmograph.