• Proceedings of the Korean Society of Precision Engineering Conference
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• 2013.05a
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• pp.901-902
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• 2013

• The Science & Technology
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• no.4 s.419
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• pp.76-81
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• 2004

우리가 알고 있는 분자들 중에서 DNA 만큼 관심이 대상이 되어 온 것이 또 있을까. 이 데옥시리보핵산(Deoxyribose Nucleic Acid)이 정확히 어떻게 생겼는지, 생명체에서 어떠한 역할을 담당하는지, 그리고 인간의 질병과 행동을 이해하는데 어떤 단서가 되는지를 규명하는 작업이야말로 20세기 과학자들의 마음을 사로잡은 최고의 화두였다. 이런 의미에서 과학전문지‘네이처’를 통해 DNA의 정체가 인류에게 최초로 공개된 1953년 4월 25일이야말로 과학사에서 매우 중요한 날일 것이다. 이른바‘유전자 혁명’의 신호탄이 된 DNA 구조 해명은 작년(2003년) 이맘때 벌써 50주년을 맞았다.

• YAKHAK HOEJI
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• v.26 no.3
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• pp.175-180
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• 1982

The intermediate of N'-nitrosonornicotine may bind to the guanine moiety of a G-C base pair. The hydrogen bond of the base pair may be broken and a new hydrogen bond can form between the intermediate and the guanine. It results in the "short" type of DNA repair.NA repair.

• Proceedings of the Korean Magnetic Resonance Society Conference
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• 1999.06a
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• pp.36-36
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• 1999

• Journal of the Korean Society for Precision Engineering
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• v.25 no.11
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• pp.37-44
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• 2008

• Journal of Marine Bioscience and Biotechnology
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• v.6 no.1
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• pp.1-7
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• 2014

Marine-derived pathogens threat health and life of human and animals. Therefore, rapid and specific detection methods need to be developed. Here, we summarized various groups of detection methods, including conventional method, flow cytometry, nucleic acid-based method, and protein-based method. In addition, perspective of detection technique was discussed as a unified detection system for pathogens.

• Proceedings of the Korean Powder Metallurgy Institute Conference
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• 2006.09b
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• pp.1193-1194
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• 2006

The magnetic ferrite nanoparticles were synthesized and coated by silica precursor in controlling the coating thicknesses and sizeses. The surface modification was performed with amino-functionalized organic silanes on silica coated magnetic nanoparticles. The use of functionalized self-assembled magnetic ferrite nanoparticles for nucleic acid separation process give a lot of advantages rather than the conventional silica based process.

• Plant Resources
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• v.8 no.2
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• pp.145-154
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• 2005

The antimicrobial effect of each fraction after fractionation of an ethanol extract of leaf mustard was examined in terms of nucleic acid, chloroform, ethylacetate, and butanol. The ethylacetate fraction, which showed the strongest level of antimicrobial effect among the different ethanol extract fractions of leaf mustard, was isolated and purified using silica gel column chromatography and HPLC, respectively, to obtain a single antimicrobial substance called KLM-1. The antimicrobial effect of this substance was 10 times higher than that of the ethylacetate fraction. A further study is on the way to confirm the structure of the antimicrobial substance KLM-1 through LC/Mass and NMR.

• Proceedings of the Korean Information Science Society Conference
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• 2003.10a
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• pp.64-66
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• 2003

DNA(Deoxyribo Nucleic Acid)컴퓨팅은 생체분자를 계산의 도구로 이용하는 새로운 계산 방법으로 DNA 정보 저장능력과 DNA의 상보적인 관계를 이용하여 연산을 수행하는 방법이다. 최근에는 DNA 분자들이 갖는 강력한 병렬성을 이용하여 NP-Complete 문제에 적용하는 연구가 많이 시도되고 있다. Adleman이 DNA 컴퓨팅을 이용해 해결한 HPP(Hamilton Path Problem)와는 달리 TSP(Traveling Salesman Problem)는 간선에 가중치가 추가되었기 때문에 DNA 염기배열로 표현하기가 어렵고 또한 염기배열의 길이를 줄이기 위해 고정길이 염기배열을 사용할 경우 가중치가 커지면 효율적이지 못하다. 본 논문에서는 스무딩 알고리즘(smoothing algorithm)을 사용하여 간선의 가중치를 일정한 비율로 줄인 다음 유전자 알고리즘을 사용하여 최적의 염기배열을 찾는 방법을 제안하였다.

• Asian-Australasian Journal of Animal Sciences
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• v.7 no.1
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• pp.137-145
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• 1994

Amino acid (AA) substituted diets had no influence on rumen levels of total volatile fatty acids (VFA), ammonia and ${\alpha}$-amino-N, but tended to increase molar proportions of isovalerate and counts of total viable AA utilizing and celluloytic bacteria in the rumen as compared with the control urea diet. The AA diets did not affect daily flow to the duodenum of dry matter (DM), organic mater (OM) and acid detergent fibre (ADF), and rumen digestibility of these nutrients. However, the AA diets, in particular the 10 essential AA (EAA) diet improved total digestibility of DM, OM and ADF by decreasing faecal output of these fractions. Although N flow to the duodenum and N retention were not affected with the dietary treatments, duodenal bacterial flow appeared to increase by the AA diets when it was estimated by means of 2,6-diaminopimelic acid (DAP) and nucleic acid-purine bases (PB) as markers. The results suggest that AA supplements to a urea diet could improve feed utilization by stimulating microbial activity and proliferation in the rumen but and increased microbial activity per se is not necessarily associated with improvement of feed conversion.