• Journal of Nutrition and Health
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• v.41 no.5
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• pp.402-413
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• 2008

This study was performed to investigate Apolipoprotein E phenotypes and the relationship among lipid levels, nutrient intakes, lifestyles and risk factors between subjects with and without hyperlipidemic risk. The data were collected from 675 industrial male workers who had completed annual medical examination. Compared to the normal group, the hyperlipidemic risk group in Apo E3 and E4 had significantly higher BMI (p < 0.05) and showed significantly higher body fat (%), waist circumference and WHR in all types of Apo E (p < 0.05). In addition, the hyperlipidemic risk group had significantly higher total cholesterol, LDL-cholesterol, triglyceride and AI than the normal group in all types of Apo E (p < 0.05). Intakes of protein, calcium, phosphorus, iron, vitamin A, vitamin B1, vitamin B2, vitamin C and niacin in Apo E3 were significantly lower in the hyperlipidemic risk group than in the normal group (p < 0.05). In the logistic regression analysis, after adjustment for other factors, Apo E2 + E4, waist and WHR were the significant risk factors associated with hyperlipidemia, but protein intakes were associated with significantly lower risks of hyperlipidemia (p < 0.05). In conclusion, genetic factor (Apo E2 or Apo E4), anthropometric index and nutrient intake seem to influence hyperlidemic risk. Further studies and efforts will be needed to evaluate the independent relationships among hyperlipidemic risk factors.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.16
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• pp.6905-6910
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• 2014

Background: The relation ofsurvivin gene expression to survival and surgical prognostic factors in the patients with endometrial carcinoma is unclear. Materials and Methods: In this study, 62 cases who were operated due to endometrial carcinoma were investigated between 2003 and 2011 in the the gynecological oncology clinic of Female Disease Training and Investigation Hospital of Etlik Zubeyde, Hanim, Turkey. Clinical and surgical prognostic factors were investigated by screening the records of these cases. With the standard streptavidin-biotin immune peroxidase method, cytoplasmic and nuclear expression of survivin was investigated in sections with specific antibodies (1:100, diagnostic Bio Systems, USA) primer. The aim was to elucidate any relation between survivin expression and defined prognostic factors and survival. Results: There was no statistically significant relationship between cytoplasmic and nuclear indexes identified for survivin and age, body mass index, the levels of preoperative hemoglobin, platelet and Ca 125, stage, grade, lymph node meastasis, the number of meta statical lymph nodes (total, paraaortic and pelvic), myometrial invasion, serosal invasion, adnexal involvement, the presence of acid in the first diagnosis, the involvement of omentum, the adjuvant treatment application of the cases, the presence of recurrence and rate of mortality (p>0.05). Statistical significance was noted for the presence of advanced stage lymph node metastasis (pelvic, paraaortic, pelvic and paraaortic), serosal involvement, positive cytology, lymph vascular space invasion, intra abdominal metastasis, and omentum involvement. When investigated the relation between cytoplasmic and nuclear survivin indexes and total survival, the result was not statistically significant (p>0.05). Conclusions: In our study, there was no statistically significant relationship between the rates of cytoplasmic and nuclear survivin expression with identified prognostic factors and total or non-disease survival.

• Nuclear Engineering and Technology
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• v.41 no.3
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• pp.247-270
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• 2009

This paper reviews studies on information searching behavior in process control systems and discusses some implications learned from previous studies for use in human factors studies on nuclear power plants (NPPs) main control rooms (MCRs). Information searching behavior in NPPs depends on expectancy, value, salience, and effort. The first quantitative scanning model developed by Senders for instrument panel monitoring considered bandwidth (change rate) of instruments as a determining factor in scanning behavior. Senders' model was subsequently elaborated by other researchers to account for value in addition to bandwidth. There is also another type of model based on the operator's situation awareness (SA) which has been developed for NPP application. In these SA-based models, situation-event relations or rules on system dynamics are considered the most significant factor forming expectancy. From the review of previous studies it is recommended that, for NPP application, (1) a set of symptomatic information sources including both changed and unchanged symptoms should be considered along with bandwidth as determining factors governing information searching (or visual sampling) behavior; (2) both data-driven monitoring and knowledge-driven monitoring should be considered and balanced in a systematic way; (3) sound models describing mechanisms of cognitive activities during information searching tasks should be developed so as to bridge studies on information searching behavior and design improvement in HMI; (4) the attention-situation awareness (A-SA) modeling approach should be recognized as a promising approach to be examined further; and (5) information displays should be expected to have totally different characteristics in advanced control rooms. Hence much attention should be devoted to information searching behavior including human-machine interface (HMI) design and human cognitive processes.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.1
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• pp.377-380
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• 2016

Background: Epidemiological data on thyroid cancer and associated risk factors are scarce in our setting. The present study was therefore designed to gather data which could be helpful in providing insights to thyroid physicians and surgeons for better management of affected patients. Purpose: To determine the frequency of carcinoma thyroid among patients presenting with goiter and its association with TSH, Tg/ATg and other demographic factors. Materials and Methods: A total of 73 adult patients of either gender with solitary solid cold nodules and/or multi-ndoular goiter (MNG) with predominant solid cold nodules were enrolled. All surgically resected samples were sent for histopathology. The frequency of thyroid cancer and its subtypes was noted and tested for association with gender, age (< or ${\geq}40years$), recent increase in swelling size, TSH, Tg and ATg. Results: Thyroid cancer was diagnosed in 26% (n=19) of the patients, 14 (73.7%) being diagnosed with papillary thyroid cancer and 5 (26.3%) with follicular thyroid cancer. No other subtypes were noted. Presence of thyroid cancer was significantly associated with recent increase in swelling size and higher TSH Values mean TSH values (P<0.05). No significant association was found with gender, age, Tg and ATg values (P>0.05). Conclusions: Overall percentage of thyroid cancer in our study sample was found to be 26%, with a predominance of papillary over follicular lesions. Rates were significantly higher in patients who had history of recent increase in swelling size and higher and higher pre-surgery TSH values.

• Proceedings of the ESK Conference
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• 1996.10a
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• pp.47-55
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• 1996

This study developed a comprehensive and easily applicable nuclear reactor control system evaluation method using reactor operators behavioral and mental workload database. A proposed control panel design cycle consists of the 5 steps: (1) finding out inconvenient, erroneous, and mentally stressful factors for the proposed design through evaluative experiments, (2) drafting improved design alternatives considering detective factors found out in the step (1), (3) comparative experiements for the design alternatives, (4) selecting a best design alternative, (5) returning to the step (1) and repeating the design cycle. Reactor operators behavioral and mental workload database collected from evaluative experiments in the step (1) and comparative experiments in the step (3) of the design cycle have a key roll in finding out defective factors and yielding the criteria for selection of the proposed reactor control systems. The behavioral database was designed to include the major informations about reactor operators' control behaviors: beginning time of operations, involved displays, classification of observational behaviors, dehaviors, decisions, involved control devices, classification of control behaviors, communications, emotional status, opinions for man-machine interface, and system event log. The database for mental workload scored from various physiological variables-EEG, EOG, ECG, and respir- ation pattern-was developed to indicate the most stressful situation during reactor control operations and to give hints for defective design factors. An experimental test for the evaluation method applied to the Compact Nuclear Simulator (CNS) installed in Korea Atomic Energy Research Institute (KAERI) suggested that some defective design factors of analog indicators should be improved and that automatization of power control to a target level would give relaxation to the subject operators in stressful situation.

• Proceedings of the Korean Radioactive Waste Society Conference
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• 2004.06a
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• pp.85-96
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• 2004

This paper is to study on the decommissioning cost estimation for nuclear facilities of advanced nuclear organizations and countries for deriving the cost factors to be taken considerations into accomplishing decommissioning projects. Of cost categories producing the factors of decommissioning costs, dismantling and waste processing & disposals activities are examined to increase the its costs. Of labor, materials and other costs categories, labor costs are summarized to have overall majorities in the decommissioning cost factors. The main parameters of all factors affecting the decommissioning costs are analyzed as work difficulty, regional labor costs, peripheral cost, disposal cost and final burial costs.

• Nuclear Engineering and Technology
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• v.55 no.8
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• pp.2897-2904
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• 2023

The Standardized Plant Analysis Risk-Human Reliability Analysis (SPAR-H) method is a widely used method in human reliability analysis (HRA). Performance shaping factors (PSFs) refer to the factors that may influence human performance and are used to adjust nominal human error probabilities (HEPs) in SPAR-H. However, the PSFs are assumed to be independent, which is unrealistic and can lead to unreasonable estimation of HEPs. In this paper, a new method is proposed to handle the dependencies among PSFs in SPAR-H to obtain more reasonable results. Firstly, the dependencies among PSFs are analyzed by using decision-making trial and evaluation laboratory (DEMATEL) method. Then, PSFs are assigned different weights according to their dependent relationships. Finally, multipliers of PSFs are modified based on the relative weights of PSFs. A case study is illustrated that the proposed method is effective in handling the dependent PSFs in SPAR-H, where the duplicate calculations of the dependent part can be reduced. The proposed method can deal with a more general situation that PSFs are dependent, and can provide more reasonable results.

• Journal of the Ergonomics Society of Korea
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• v.35 no.4
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• pp.247-261
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• 2016

Objective:The aim of this paper is to discuss the nuclear safety culture in Korea. Background: Recently, Korean nuclear field has met a strong anti-nuclear trend after a few happenings, as well as Fukushima accident, which are turned out to be caused by organizational pitfalls and safety culture defects in general. Method: We review the concepts and constructs of safety culture based on the brief history of the nuclear safety culture that IAEA mainly raised after the Chernobyl accident in 1986. Additionally, we give a comparative discussion on the approach to the safety culture with U.S. Results: Finally, we discuss the three technical domains and propose six selected domestic issues related to the nuclear safety culture for coping with the demanding requests on nuclear safety in Korea. Conclusion and Application: We suggest several recommendations and a research direction in the form of a re-start line for the nuclear safety culture in Korea.

• Proceedings of the Korean Nuclear Society Conference
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• 2005.05a
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• pp.293-294
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• 2005

The safety analyses and evaluation works on the process and facility for ACP demonstration have been performed. The several safety factors, such as the risk, environmental, radiation, structural, criticality, were analyzed. The analysis results confirmed the reliability of the safety on the ACP process and facility during normal and accident conditions.

• Nuclear Engineering and Technology
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• v.53 no.1
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• pp.121-130
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• 2021

Cascading failure is the main cause of large blackouts in electrical power systems; this paper analyzes a cascading failure in Hanbit nuclear power plant unit two (2) caused by a circuit breaker (CB) operation failure. This malfunction has been expanded to the loss of offsite power (LOOP). In this study, current practices are reviewed and then the methodologies of how to prevent cascading failures in protection power systems are introduced. An overview on the implementation of IEC61850 GOOSE messaging-based zone selective interlocking (ZSI) scheme as key solution is proposed. In consideration of ZSI blocking time, all influencing factors such as circuit breaker opening time, relay I/O response time and messages travelling time in the communication network should be taken into account. The purpose of this paper is to elaborate on the effect of cascading failure in NPP electrical power protection system and propose preventive actions for this failures. Finally, the expected advantages and challenges are elaborated.