• Asian-Australasian Journal of Animal Sciences
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• v.30 no.11
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• pp.1651-1659
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• 2017

Objective: Lao PDR's recent accession to the World Trade Organization necessitates a greater understanding of the patterns and risk of livestock production in order to better align national policy with the Agreement on the Application of Sanitary and Phytosanitary Measures. This eco-health study was conducted to improve understanding of the interrelations between market chains and zoonotic infection risks at two strategic cross border points between Lao PDR, Thailand and Viet Nam. Methods: Information gained from smallholder farmer/trader interviews was integrated with serological surveys for pig-associated zoonoses-including hepatitis E virus (HEV), Taenia solium (T. solium) and trichinella-to identify potential linkages between disease risk and pig production and slaughter in low input systems common across the country. Results: Trichinella and HEV exposure was high in both humans and pigs in both study areas, significantly associated with pig slaughter and the subsequent consumption and handling of raw pork products. T. solium demonstrated a strong geographical and ethnic association with the northern study area bordering Vietnam. With the right knowledge and accessible, affordable inputs, the majority of smallholder farmers indicated a willingness to invest more in pig production, which could simultaneously improve livelihoods and decrease exposure to HEV, Trichinella, and T. solium through increased access to formal markets and an improved slaughter processes. Conclusion: The linkages identified when assessing disease risk in the context of potential economic and cultural drivers of transmission highlight the importance of a systems-based approach for the detection and control of zoonotic disease, and contributes to an improved understanding of the Lao PDR livestock sector.

• Proceedings of the Korea Society of Environmental Toocicology Conference
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• 2003.10a
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• pp.27-27
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• 2003

Lake Texoma is located on the border of southern Oklahoma and northern Texas. It has 93,000 surface acres, and is a focus of the recreation, and farming industries in the region. There are potential stressors around the Lake Texoma watershed that may cause adverse ecological effects in the lake. System assimilative capacity (SAC) is the ability of abiotic and biotic processes to atteuniate the stressors. SAC Exceeded indicates potential of occuring adverse eco-effects. A number of representative chemical release sites and stressor sources in the surrounding watershed were characterized, and several impact sites having stressors sources, such as being near agriculture, landfills, housing areas, oil production fields and heavy use recreational activity, were selected for surface water, sediment, and groundwater monitoring. A paired reference site, having similar physical characteristics as its impact site, was also chosen based on its proximity to the impact site. Lake water samples were collected at locations identified as marina entrance, gasoline filling station, and boat dock at five marinas selected on Lake Texoma from September 1999 to December 2001. Paired water and sediment samples were also collected. Groundwater samples were collected at about 70 producing monitoring wells. Water quality parameters measured were inorganics (nitrate, nitrite, orthophosphate, ammonia, sulfate, and chloride), dissolved methane, total organic carbon (TOC) (or DOC), volatile organic compounds (VOCs) such as methyl tert-butyl ether (MTBE) and BTEX, and a suite of metals. Biotic communities were evaluated at impact and reference sites. Five basic components were measured; two terrestirial components (plants and bird comminitires) and three aquatic components (benthic inverbrates, litteral-zone fishes, ecosystem attribures). Potential impacts to these comminites were evaluated.

• International Journal of Computer Science & Network Security
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• v.21 no.6
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• pp.319-328
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• 2021

Parallel administration of numerous drugs increases Drug-Drug Interaction (DDI) because one drug might affect the activity of other drugs. DDI causes negative or positive impacts on therapeutic output. So there is a need to discover DDI to enhance the safety of consuming drugs. Though there are several DDI system exist to predict an interaction but nowadays it becomes impossible to maintain with a large number of biomedical texts which is getting increased rapidly. Mostly the existing DDI system address classification issues, and especially rely on handcrafted features, and some features which are based on particular domain tools. The objective of this paper to predict DDI in a way to avoid adverse effects caused by the consumed drugs, to predict similarities among the drug, Drug pair similarity calculation is performed. The best optimal weight is obtained with the support of KHA. LSTM function with weight obtained from KHA and makes bets prediction of DDI. Our methodology depends on (LSTM-KHA) for the detection of DDI. Similarities among the drugs are measured with the help of drug pair similarity calculation. KHA is used to find the best optimal weight which is used by LSTM to predict DDI. The experimental result was conducted on three kinds of dataset DS1 (CYP), DS2 (NCYP), and DS3 taken from the DrugBank database. To evaluate the performance of proposed work in terms of performance metrics like accuracy, recall, precision, F-measures, AUPR, AUC, and AUROC. Experimental results express that the proposed method outperforms other existing methods for predicting DDI. LSTMKHA produces reasonable performance metrics when compared to the existing DDI prediction model.

• International Journal of Computer Science & Network Security
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• v.22 no.2
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• pp.424-435
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• 2022

When the owners of the intellectual property rights of digital content have lost control over it in the digital environment, there emerged fears that the intellectual property laws, especially copyright law, would not be effective as in the material (Offline ) world. The reason is that the digital environment helps to reproduce copies in high quality and at almost no cost, while copyright law protection has been limited to programs embedded in CDs. According to copyright laws, the owner of the program did not have the right to prevent buyers of the initial physical copy of the program from copying and reselling it to more than one individual without the permission of the original owner. As a result, business owners have invented the idea of licensing digital content and programs instead of selling them. They set out terms that serve their commercial interests regardless of their abuse to intellectual property laws or even the rules of the traditional contract to sell a material property. The abuse has resulted from the way those terms are concluded and the heavy rules that are unfair to consumer rights. Therefore, business owners insisted on dealing with the website and its programs and digital content as material property. Here raises the question of whether the website and its digital content are subject to the protection of copyright law or the rules of the traditional contract or licensing contracts. As the answer to this question affects the protection of consumer rights, is it possible to find a balance between it and the protection of the owners of digital programs' rights.That is what we will discuss in this paper.

• International Journal of Computer Science & Network Security
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• v.22 no.4
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• pp.274-284
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• 2022

By explaining the essence of corporate governance as well as disclosure and transparency, the study examined the guarantees of applying disclosure and transparency to firms listed on the Saudi stock exchange. The research also addressed the disclosure and transparency duties of firms listed on the Saudi stock exchange. Finance to prepare a prospectus, as the Capital Market Authority's regulations required that the prospectus includes information that enables the investor in securities to make his investment decision based on real foundations based on the issuing company's financial position and to ensure that companies fulfill that disclosure in the prospectus. Firms who fail to disclose are required by law to do so, and the Capital Market Authority's laws mandate companies listed on the financial market to regularly report fundamental events linked to the issuer or the securities issued by it. The Capital Market Authority must make it available to the public dealing with the business issuing the securities, and The Capital Market Authority's Law and Regulations have imposed fines on corporations that do not comply with disclosure and make the Board of Director's report available. The research focused on activities that the legislator deemed to be a breach of the obligation of openness, such as the danger of many measures aimed at ensuring the impartiality and transparency of trading in the Saudi financial market, as well as the absence of conflicts of interest. The research also addressed the sanctions imposed on The source for failing to meet the obligation of disclosure and openness, as well as the mechanisms of compensating persons harmed by the failure to meet that responsibility.

• Strategy21
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• s.31
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• pp.27-56
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• 2013

The United Nations Command (UNC) and the communist North failed to reach an agreement on where the maritime demarcation line should be drawn in the process of signing a truce after the Korean War because of the starkly different positions on the boundary of their territorial waters. As a result, the Armistice Treaty was signed on July 1953 without clarification about the maritime border. In the following month, Commander of the UNC unilaterally declared the Northern Limit Line (NLL) as a complementing measure to the Armistice. Referring to this, North Korea and its followers in South Korea wrongfully argue that the NLL is a "ghost line" that was established not based on the international law. However, one should note that the waters south of the NLL has always been under South Korea's jurisdiction since Korea's independence from Japan on August 15, 1945. There is no need to ask North Korea's approval for declaring the territorial waters that had already been under our sovereign jurisdiction. We do not need North Korea's approval just as we do not need Japan's approval with regard to our sovereign right over Dokdo. The legal status of the NLL may be explained with the following three characteristics. First, the NLL is a de facto maritime borderline that defines the territorial waters under the respective jurisdiction of the two divided countries. Second, the NLL in the West Sea also serves as a de facto military demarcation line at sea that can be likened to the border on the ground. Third, as a contacting line where the sea areas controlled by the two Koreas meet, the NLL is a maritime non-aggression line that was established on the legal basis of the 'acquiescence' element stipulated by the Inter-Korea Basic Agreement (article 11) and the Supplement on the Non-aggression principle (article 10). Particularly from the perspective of the domestic law, the NLL should be understood as a boundary defining areas controlled by temporarily divided states (not two different states) because the problem exists between a legitimate central government (South Korea) and an anti-government group (North Korea). In this sense, the NLL problem should be viewed not in terms of territorial preservation or expansion. Rather, it should be understood as a matter of national identity related to territorial sovereignty and national pride. North Korea's continuous efforts to problematize the NLL may be part of its strategy to nullify the Armistice Treaty. In other words, North Korea tries to take away the basis of the NLL by abrogating the Armistice Treaty and creating a condition in which the United Nations Command can be dissolved. By doing so, North Korea may be able to start the process for the peace treaty with the United States and reestablish a maritime line of its interest. So, North Korea's rationale behind making the NLL a disputed line is to deny the effectiveness of the NLL and ask for the establishment of a new legal boundary. Such an effort should be understood as part of a strategy to make the NLL question a political and military dispute (the similar motivation can be found in Japan's effort to make Dokdo a disputed Island). Therefore, the South Korean government should not accommodate such hidden intentions and strategy of North Korea. The NLL has been the de facto maritime border (that defines our territorial waters) and military demarcation line at sea that we have defended with a lot of sacrifice for the last sixty years. This is the line that our government and the military must defend in the future as we have done so far. Our commitment to the defense of the NLL is not only a matter of national policy protecting territorial sovereignty and jurisdiction; it is also our responsibility for those who were fallen while defending the North-Western Islands and the NLL.

• Journal of the Economic Geographical Society of Korea
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• v.18 no.3
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• pp.296-318
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• 2015

The Bru-Van Kieu, one of ethnic minorities in Vietnam, have lived in the mountainous area along the border with Laos for centuries. Approximately by the end of the Second Indochina War, the Bru-Van Kieu were still a kinship-based and non-stratified societal group relying mainly on subsistence economy. Their traditional physical geography, nonetheless, has been transformed vigorously during the last few decades as a result of state-formation processes and changes in macro-economic policies. The paper aims to examine how ethnic minority adapt their livelihood to challenges instigated by macro political and economic processes. By examining livelihood adaptation of the Bru-Van Kieu, the study also identifies strategies that ethnic minorities use to negotiate with more powerful political and economic forces. The authors argue that the Bru-Van Kieu have deployed a strategy combining everyday resistance to maintain their limited social and cultural agencies and utilizing of these agencies in economic adaptation with other cross-ethnic non-state actors, enabling them to tap into new type of resources and opportunities.

• The Korean Journal of Physiology
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• v.29 no.1
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• pp.69-80
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• 1995

Renal proximal tubular hypertrophy and hyperfunction are known to be early manifestations of experimental and human diabetes. As the hypertrophy and hyperfunction have been suggested to be central components in the progression to renal failure, an understanding of their underlying causes is potentially important for the development of therapy. A primary rabbit kidney proximal tubule cell culture system was utilized to evaluate the possibility that the renal proximal tubular hypertrophy and hyperfunction observed in vivo in diabetes mellitus, can be attributed to effects of elevated glucose levels on membrane transport systems. Primary cultures of rabbit proximal tubules, which achieved confluence at 10 days, exhibited brush-border characteristics typical of proximal tubular cells. Northern analysis indicated $2.2{\sim}2.3$ and 2.0 kb Na/glucose cotransporter RNA species appeared in fresh and cultured proximal tubule cells after confluence, repectively. The cultured cells showed reduced Na/glucose cotransporter activity compared to fresh proximal tubules. Primary cultured proximal tubule cells incubated in medium containing 20 mM glucose have reduced ${\alpha}-MG$ transport compared to cells grown in 5 mM glucose. In the proximal tubule cultures incubated in medium containing 5 mM or 20 mM glucose, phlorizin at 0.5 mM inhibited 0.5 mM ${\alpha}-MG$ uptake by 84.35% or 91.85%, respectively. The uptake of 0.5 mM ${\alpha}-MG$ was similarly inhibited by 0.1 mM ouabain (41.97% or 48.03% inhibition was observed, respectively). In addition, ${\alpha}-MG$ uptake was inhibited to a greater extent when $Na^{+}$ was omitted from the uptake buffer (81.86% or 86.73% inhibition was observed, respectively). In cell homogenates derived from the primary cells grown in 5 mM glucose medium, the specific activity of the Na/K-ATPase $(6.17{\pm}1.27\;{\mu}mole\;Pi/mg\;protein/hr)$ was 1.56 fold lower than the values in cell homogenates treated with 360 mg/dl D-glucose, 20 mM $(9.67{\pm}1.22\;{\mu}mole\;Pi/mg\;protein/hr)$. Total $Rb^{+}$ uptake occurred at a significantly higher rate (1.60 fold increase) in primary cultured rabbit kidney proximal tubule cell monolayers incubated in 20 mM glucose medium $(10.48{\pm}2.45\;nM/mg\;protein/min)$ as compared with parallel cultures in 5 mM glucose medium. $Rb^{+}$ uptake rate in 5 mM glucose medium was reduced by 28% when the cultures were incubated with 1 mM ouabain. The increase of the $Rb^{+}$ uptake by rabbit kidney proximal tubule cells in 20 mM glucose could be attributed primarily to an increase in the rate of ouabain-sensitive $Rb^{+}$ uptake $(5\;mM\;to\;20\;mM;\;4.68{\pm}0.85\;to\;8.38{\pm}1.37\;nM/mg\;protein/min)$. In conclusion, the activity of the renal proximal tubular Na,K-ATPase is elevated in high glucose concentration. In contrast, the activity of the Nafglucose cotransport system is inhibited.

• Journal of the Korean Geographical Society
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• v.50 no.6
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• pp.717-734
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• 2015

The Toyo Bunko (東洋文庫) in Tokyo, Japan is one of the largest library that holds the Korean old geographical documents. About 200 topographies of counties and prefectures, including Giinhansangnyang 杞人間商量 which recorded compilation and improvement plan of the geographical annals belong to it. Several maps and geographical annals of Joseon Period possessed in the Toyo Bunko are set high values on geography since the materials are only belong to it and have not yet been found in Korea. There are very important map collections including six copies of Daedongyeojido 大東輿地圖(1861, 1864) by Kim Jeongho(金正浩) and Suseonjeondo 首善全圖 by Kim, Jungho, collectible stamp of Maema Kyosaku(前間恭作) is imprinted on it, and Gangyeokjundo 疆域全圖 and Dongyeodo 東輿圖 which made with 20-ri and 10-ri grid, owned by Sidehara Daira(幣原坦). Especially Gwanbukjido 關北地圖 which is the northern border map recorded the Lee Sam's(李森) preface who served as a military official of Hamgyeong and Pyeongan Province in early 18th century. These maps and some other maps have a historical value to supplement of the history of Korean Cartography.

• Korean Journal of Plant Resources
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• v.36 no.1
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• pp.62-90
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• 2023

This study was conducted to study the vascular plants of Balbaeksan, located on the border between Gyeongsan-si and Cheongdo-gun, Gyeongsangbuk-do. It was performed 13 times from September 2020 to November 2021, and the investigated vascular plants were identified as a total of 93 families, 302 genera, 485 species, 10 subspecies, 40 varieties, 13 varieties, and 545 taxa. Endemic plants were investigated in 18 taxa, 9 taxa of rare plants; Vulnerable (VU) 5 taxa, Least concerned (LC) 3 taxa, Data Deficient (DD) 1 taxa, Red List plants 5 taxa; 3 taxa of least concerned (LC), 2 taxa of Not Evaluated (NE), 183 taxa of biological resources subject to export approval, 78 taxa of specific taxonomy; There were 9 taxa of grade IV, 20 taxa of grade III, 20 taxa of grade II, and 28 taxa of grade I. 4 taxa of plants subject to climate change adaptation; 2 taxa of endemic plants, 1 taxa of southern plants, 1 taxa of northern plants, 4 taxa of climate change biomarker species, 2 taxa of candidate species of climate change biomarker, 65 taxa of exotic plants, and 3 taxa of ecosystem disturbance species. Plants 235 taxa (43.1%), medicinal plants 257 taxa (47.2%), ornamental plants 148 taxa (27.2%), woody plants 54 taxa (9.9%), herbaceous plants 37 taxa (6.8%), industrial plants 15 Taxa (2.8%), 11 taxa (2.0%) of fiber-bearing plants, and plants of unknown use were identified as 73 taxa (13.4%). The flora of Mt. Balbaek was investigated for the first time, and plants to be preserved in order to secure useful plant resources and biological sovereignty were identified. So continuous monitoring is necessary to prevent the introduction of foreign plants that may be caused by the recent increase in the number of people coming and going.