• Title/Summary/Keyword: North Central Region

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Clinical, Histopathological and Molecular Characteristics of Metastatic Breast Cancer in North-Eastern Kazakhstan: a 10 Year Retrospective Study

  • Abiltayeva, Aizhan;Moore, Malcolm A;Myssayev, Ayan;Adylkhanov, Tasbolat;Baissalbayeva, Ainur;Zhabagin, Kuantkan;Beysebayev, Eldar
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.10
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    • pp.4797-4802
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    • 2016
  • Background: Breast cancer (BC) is the top cancer among women worldwide and has been the most frequent malignancy among Kazakhstan women over the past few decades. Information on clinical and histopathological features of metastatic breast cancer (MBC), as well as the distribution of molecular subtypes is limited for Kazakh people. Materials and Methods: The present observational retrospective study was carried out at Regional Oncologic Dispensaries in the North-East Region of Kazakhstan (in Semey and Pavlodar cities). Сlinical and histopathological data were obtained for a total of 570 MBC patients in the 10 year period from 2004-2013, for whom data on molecular subtype were available for 253. Data from hospital charts were entered into SPSS 20 for analysis by one-way ANOVA analysis of associations of different variables with 1-5 year survival. Pearson correlation and linear regression models were used to examine the relation between parameters with a p-value < 0.05 considered statistically significant. Results: No significant relationships were evident between molecular subtype and survival, site of metastases, stage or ethnicity. Young females below the age of 44 were slightly more likely to have triple negative lesions. While the ductal type greatly predomonated, luminal A and B cases had a higher percentage with lobular morphology. Conclusions: In this select group of metastatice brease cancer, no links were noted for survival with molecular subtype, in contrast to much of the literature.

The Biology of the Pelagic Amphipod, Primno macropa Guer., in the Western North Pacific: 2. Geographical Distribution and Vertical Distributional Pattern

  • Yoo, Kwang-Il
    • The Korean Journal of Zoology
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    • v.15 no.2
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    • pp.87-91
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    • 1972
  • For the geographical distribution of Primno macropa it was distributed over all stations investigated, except surface tow in East China Sea, through all seasons. It is believed that this species is most cosmopolitan species in the western North Pacific. Veritical distributional range of P. macropa indicates at depths from surface to more than 1,500m and most deeper recored for the vertical occurrence was obtained from depth of 1,650-2,220m in Station 229 $(34^\\circ 44.3'N, 140^\\circ 04.4'E)$, off Nojima-Zaki, Central Japan. For the vertical distributional and migrational pattern it is a typical diurnal migrant in the western North Pacific; at depths from 100m to 500m at night and 400m to 700m at day in Oyashio population, and from surface to 200m at night and from 100m to 300m at day in Kuroshio population. In Kuroshio area, the population of P. macropa was distributed in somewhat shallower layers than in Oyashio area and it is suggested that the populations is different in region and season according to their stages consisting the population.

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Tectonic Features of a Triple-Plate Junction in Hokkaido Using Local Seismic Tomography

  • Kim, So-Gu;Bae, Hyung-Sub;Pak, Sang-Pyo
    • Proceedings of the KSEG Conference
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    • 2005.04a
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    • pp.101-106
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    • 2005
  • The three-dimensional Tomography developed by Kim and Bae(2004) was applied to 64,024 P and 64,618 S wave arrival times observed at 238 seismic stations for 4050 local earthquakes in the depth range from 0 to 300 km in and around Hokkaido, Japan. High and low velocity zones for Vp/Vs were clearly imaged in and around Hokkaido. The upper seismic planes of the double seismic zone (DSZ) were found in the subducted Pacific Plate beneath Hokkaido at depth of 40- 80 km, which produced high seismicity around Hokkaido. The findings of high Vp/Vs anomalies beneath the Moho discontinuity supports an evidence of a surface triple-collision hypothesis prepared by Moriya(1994) that the Kuril Arc(Okhotsk Plate or North American Plate) is colliding against the NE Japanese Arc(Amurian Plate or Eurasian Plate), along and beneath the Hidaka Mountain Range, and at the same time the Pacific Plate is subducting into these two plates, making an equilibrium of tectonic forces along the Hikada Mountain Range (HMR) corner and the central tectonic axis(142 ~ 143E) in Hokkaido. The low Vp and Vs were also found in east and west along the central tectonic axis in which the focal mechanism represents the extensional forces. These phenomena are also consistent with low Bouguer gravity anomalies in this region. It is understood why most of great earthquakes occurred outside Hokkaido where the balance of tectonic forces are breaking from the triple junction of three tectonic forces in Hokkaido.

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Precambrian Geology and Structure of the Central Region of South Korea

  • Kim, Ok Joon
    • Economic and Environmental Geology
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    • v.5 no.4
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    • pp.231-239
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    • 1972
  • The central region of South Korea is composed of Precambrian formations and Jurassic Daebo granites and is divided tectonically into three provinces, that is, the Ok chon geosynclinal zone in the middle, the Kyonggi massif on the north and northwest side, and the Ryongnam massif on the south and southeast side. The general trend of the Okchon geosynclinal zone and the distribution of Daebo granites is northeast, the Sinian direction. The Kyonggi massif is composed of Precambrian Y onchon system, Sangwon system, gneisses, and Daebo granites, and the Ryongnam massif also Precambrian Ryongnam and Yulri systems, gneisses, and Daebo granites. Precambrian formations in both areas are of flysch type sediments and may be roughly correlated with each other. These formations except Sangwon and Yulri systems are thought to be early to middle Precambrian age and have acted as basement for the Okchon geosyncline where late Precambrian Okchon system was deposited. The Okchon geosynclinal zone is divided into paleogeosynclinal zone to southwestern parts where the Okchon system is distributed, and neogeosynclinal zone to northeastern parts where nonmetamorphosed Paleozoic sediments are dominantly cropped out. Both zones are separated by upthrust created by Daebo orogeny of Jurassic period, which continues southwesterly to bind the Okchon geosynclinal zone and the Ryongnam massif at southwestern parts bisecting Korea peninsula diagonally. Three periods of structural development are recognized in the area. Folds and faults of preTriassic age prevail in the Kyonggi massif. Many isoclinal folds and thrusts originated by Jurassic Daebo orogeny are aligned in the Okchon paleogeosynclinal zone paralleling to the geosynclinal axis so that same formation appears repeatedly in narrow strips, whereas fold axis in neogeosynclinal zone trerid west-northwesterly which might be of Triassic in age and modified by later Daebo orogeny. Discontinuity of geology and structure of Okchon geosynclinal zone is attributed to shifting of the geosyncline through geologic time.

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A Review of World Heritage Sites in Vietnam (베트남의 세계유산 등재 현황과 특징)

  • Joo, Kyeongmi
    • Conservation Science in Museum
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    • v.18
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    • pp.93-114
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    • 2017
  • This paper reviewed a total of eight sites in Vietnam inscribed on UNESCO's World Heritage List. The sites include the five cultural heritage sites(the Central Sector of the Imperial Citadel of Thang Long, Citadel of the Ho Dynasty, My Son Sanctuary, Hoi An Ancient Town, and Complex of Hué Monuments), two natural heritage sites (Ha Long Bay and Phong Nha-Ke Bang National Park), and one mixed heritage site (Trang An Landscape Complex). All these sites are situated in the northern and central areas of the country, and no inscribed site exists in the south. The two natural heritage sites and the Trang An Landscape Complex, a mixed heritage site, feature a typical Karst topographic landscape with limestone caves, cliffs, stalactites, and underwater rivers. The four cultural heritage sites as well as Hoa Lu of the Trang An Landscape Complex mainly consist of remains of the citadels of the capitals of ancient Vietnamese dynasties from the northern region. Due to the complex political situation in the aftermath of the long Vietnam War and the subsequent unification of the country, the Vietnamese government has been giving priority for inscription on the World Heritage List to sites with historical legitimacy in the northern region. It is hoped that the Vietnamese government will pursue more integrated cultural policies in the future that can help reduce north-south regional disparities.

Multiple Linear Regression Model for Prediction of Summer Tropical Cyclone Genesis Frequency over the Western North Pacific (북서태평양 태풍발생빈도 예측을 위한 다중회귀모델 개발)

  • Choi, Ki-Seon;Cha, Yu-Mi;Chang, Ki-Ho;Lee, Jong-Ho
    • Journal of the Korean earth science society
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    • v.34 no.4
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    • pp.336-344
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    • 2013
  • This study has developed a multiple linear regression model (MLRM) for the seasonal prediction of the summer tropical cyclone genesis frequency (TCGF) over the western North Pacific (WNP) using the four teleconnection patterns. These patterns are representative of the Siberian high Oscillation (SHO) in the East Asian continent, the North Pacific Oscillation (NPO) in the North Pacific, Antarctic oscillation (AAO) near Australia, and the circulation in the equatorial central Pacific during the boreal spring (April-May). This statistical model is verified by analyzing the differences hindcasted for the high and low TCGF years. The high TCGF years are characterized by the following anomalous features: four anomalous teleconnection patterns such as anticyclonic circulation (positive SHO phase) in the East Asian continent, pressure pattern like north-high and south-low in the North Pacific, and cyclonic circulation (positive AAO phase) near Australia, and cyclonic circulation in the Nino3.4 region were strengthened during the period from boreal spring to boreal summer. Thus, anomalous trade winds in the tropical western Pacific (TWP) were weakened by anomalous cyclonic circulations that located in the subtropical western Pacific (SWP) in both hemispheres. Consequently, this spatial distribution of anomalous pressure pattern suppressed convection in the TWP, strengthened convection in the SWP instead.

A Tale of Four Provinces: A Comparative Analysis of Provincial Governance in Vietnam (사성사색(四省四色)의 베트남 지방성(省) 거버넌스)

  • KIM, Yong Kyun
    • The Southeast Asian review
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    • v.28 no.4
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    • pp.115-159
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    • 2018
  • This paper situates 63 provinces of Vietnam on a two-dimensional governance space, according to their levels of both economic and political governance, and systematically explains the two-dimensional distribution of provincial governance. It presents three sets of explanatory factors: the amount of foreign direct investment (FDI) that each province has attracted, the combination of provincial urbanization and population density, and the North Central Coast region factor. Provinces that score high in both economic and political governance tend to have received a good amount of FDI and to be highly urbanized and densely populated whereas provinces that score low in both governance dimensions tend to have the opposite characteristics. Provinces that are high in economic governance but low in political governance are those that have received the greatest amount of FDI and tend to be highly urbanized yet relatively sparsely populated. Provinces that are high in political governance but low in economic governance are characterized by a relatively small amount of FDI, low urbanization, and high population density. Finally, provinces in the North Central Coast region tend to score very high in political governance.

Long-term Changes of Shoreline at the East Coast in South Korea 2 - South East Coast (우리나라 동해안 해안선의 장기적 변화 2 -남부 동해안)

  • Kim, Dae Sik
    • Journal of The Geomorphological Association of Korea
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    • v.20 no.3
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    • pp.27-39
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    • 2013
  • This study grasped long-term changing tendency of shoreline during lately about 30 years in five region of South East coast, and analyzed long-term changing tendency of East coast shoreline and the factors that synthesized studies of Central and South East coast. As a result of calculating of shoreline variations using DSAS, each shoreline of Mangyangjeong and Josa region regressed mean 28.9m and 6.4m, but each shoreline of Goraebul, Daejin and Bonggil region progressed mean 25.0m, 10.6m and 18.8m. Synthesizing changing tendency of East coast shoreline, 1) progressive and regressive zones of shoreline in all regions seem to repeat. 2) looking at shoreline of south zone adjacent to lately constructed or extended breakwater progressed, because it is thought due to effect of a longshore current flowing north. 3) zones using beach relatively tends to regress shorelines. 4) progress and regress of shoreline in zones including estuary of stream are various features as change of deposit supply from a upstream region.

Heading Ecology of Rice Varieties Adaptable to the Temperature and Day-Length Conditions in North Korean Regions (북한 지역 기온과 일장 환경 적응 벼 품종의 출수생태 특성 분석)

  • Woonho Yang;Shingu Kang;Dae-Woo Lee;Mi-jin Chae
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.68 no.4
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    • pp.236-245
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    • 2023
  • We investigated the basic vegetative phase (BVP), photoperiod-sensitivity (PS), and thermo-sensitivity (TS) of 40 rice varieties to characterize their heading ecology that is adaptable to North Korean rice production areas. The ranges were 12 - 43 days for BVP, 0 - 74 days for PS, and 15 - 33 days for TS, depending on the variety. The number of days from transplanting to the heading stage (DTH) was significantly correlated with PS in the 13 major rice production regions where all 40 varieties (including early-, middle-, and mid-late-maturing varieties) were tested. DTH was significantly correlated with BVP and TS but not with PS in the 10 low-temperature regions where only 28 early-maturing varieties were tested. The heading ecology of the adaptable varieties for each region could be characterized by an exponential equation between the BVP and PS of varieties that headed at the border of the safe marginal heading date (SMHD) for each of the seven regional environments (Kaesong, Haeju, Yongyon, Singye, Sariwon, Nampo, and Pyongyang). A PS of 25 - 30 days or less was an additional adaptive trait in the Sariwon and Pyongyang environments. The varieties that reached the heading stage not later than the SMHD in six regional environments (Anju, Kusong, Sinuiju, Changjon, Wonsan, and Supung) and those that reached the heading stage not later than the late marginal heading date (LMHD) in four regional environments (Hamhung, Pyonggang, Huichon, and Kanggye) had both a PS of 26 days or less and a BVP of 25 - 28 days or less. In the Yangdok, Sinpo, and Chunggang environments, varieties that reached the heading stage not later than the LMHD for each region had a BVP of 15 - 20 days or less. The results suggested that a shortened BVP trait should be introduced to existing early-maturing rice varieties to reduce the duration of growth period to reach the heading stage.

Utilization of Evergreen Ground Covers in Central Region of Korea as Landscape Materials -Focusing on the Changes in Leaf Color Related with Light during Winter- (중부지방 상록지피식물의 조경적 이용 -광이 월동중의 엽색에 미치는 영향을 중심으로-)

  • Nam, Yu-Kyeong;Kim, Myung-Hyoe
    • Journal of agriculture & life science
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    • v.45 no.2
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    • pp.1-7
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    • 2011
  • Three evergreen ground-cover species were tested and evaluated for cold acclimation with different lights in central Korea to enrich the varieties of ground cover plants for over-wintering. Nandina domestica which recently started to be planted in central Korea had high chlorophyll unit with shade condition in both locations, Banpo and Gwacheon during winter. Light condition had no influence on chlorophyll unit in Banpo after April, meanwhile full sun condition decreased chlorophyll unit significantly in Gwacheon, which is exposed to cold wind from north. Ophiopogon japonicas had more than double chlorophyll unit in shade condition compared to that in full light condition in both investigation areas in February. In addition, higher value of L and b in shade condition had been maintained than in full sun condition throughout investigation period. However, leaves in Gwacheon were de-colorized in full sun condition after over-wintering. Pachysandra terminalis had more higher chlorophyll unit in shade condition compared to in full sun condition in both investigation areas in February. But light conditions had not effect the difference of chlorophyll unit of Gwacheon in April. Therefore, The present results suggest that evergreen ground covers with shade condition would be used as landscape materials in the capital area.