• Title/Summary/Keyword: Normal variability

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Epidural Ketamine for postoperative Analgesia -Comparison with Epidural Morphine- (경막외케타민 주입을 이용한 술후 통증관리 -경막외몰핀과의 비교-)

  • Kim, Han-Soo;Baik, Seong-Wan;Kim, Inn-Se;Chung, Kyoo-Sub
    • The Korean Journal of Pain
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    • v.1 no.2
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    • pp.192-198
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    • 1988
  • Sixty patients, of ASA physical status class I for elective operations in the lower abdomen, perineum, or lower extremities, were studied in a comparative prospective trial to evaluate the efficacy of epidural morphine and ketamine for postoperative analgesia. They were divided into two groups: an epidural morphine sulfate group (EMS group; 30 patients), and an epidural ketamine hydrochloride group (EKH group; 30 patients). Indwelling epidural catheters were placed in the patients' lumber areas (L3-4) and then all patients were anesthetized with thiopental, nitrous oxide, and halothane. After the patients had fully recovered from the anesthesia, the analgesic agents were administered epidurally via the catheter when the patients complained of pain in the postoperative period. The groups were given either 0.1 mg/kg of morphine sulfate or 0.5 mg/kg of ketamine hydrochloride administered in a volume of 10 ml of normal saline. Patients were observed for the onset and duration of postoperative analgesia and for other effects. Total doses were $5.7{\pm}0.6\;mg$ of morphine sulfate in the EMS group and $27.9{\pm}3.3\;mg$ of ketamine hydrochloride in the EKH group. The onset of analgesia was detectable within 35 min.($23.5{\pm}6.3$ min) in 86.7% (26 cases) of the EMS group and within 10 min. ($7.8{\pm}3.7$ min.) in 76.7% (23 cases) of the EKH group. Mean duration of postoperative analgesia was $22.3{\pm}2.1\;hr$. in the EMS group. In the EKH group, the duration of analgesia was shorter and variable, the range of duration was from 2 hr. to 24 hr., Cardiopulmonary changes were statistically insignificant ih both groups. Side effects such as nausea, vomiting, urinary retention, pruritus, dizziness, and headache were observed in EMS group. In the EKH group, there was no discomfort except dizziness (3 cases) and headache (1 case). Epidural ketamine was a safe technique for postoperative analgesia, but because of the variability and relative shortness in the duration of analgesia the use of this technique will require further clinical trials.

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A Study on the Establishment of a GIS Thematic Mapping Procedure for Oil Spill Monitoring Data (유류오염 모니터링 자료의 GIS 주제도 제작 절차 수립 연구)

  • Kim, Tae-Hoon;Choi, Hyun-Woo
    • Journal of the Korean Association of Geographic Information Studies
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    • v.15 no.1
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    • pp.1-15
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    • 2012
  • Marine scientific monitoring, including monitoring of oil pollution, marine ecosystems, and the marine environment in general, has been being carried out continuously in order to assess the impact of oil pollution since the Hebei Spirit oil spill in December 2007. GIS thematic maps containing visual and summarized information are very useful for conducting exploratory analyses on the spatio-temporal variability of the marine environment and marine ecosystems due to oil pollution. Defining map types and building a legend in accordance with data characteristics are essential elements for mapping. In the present study, map types were defined according to the data attributes and GIS data types for each data item and classification of data intervals for the legend was defined by using two data distribution types through a histogram analysis. The data interval method was defined as follows: If the histogram of data has a uniform distribution, an equal interval method is applied; in the case of a normal distribution, a standard deviation method is applied. In addition, thematic map templates were made for each map type through the definition of marginal elements. Through the establishment of systematic mapping methods and procedures in this study, it was possible to effectively make standardized thematic maps for various kinds of marine scientific data.

GROWTH CHANCE IN THE LIPS OF THE ADOLESCENCE (from 8 to 16 years old) (청소년기 (8세에서 16세) 구순부 성장변화에 관한 누년적 연구)

  • Kim, Young-Hee;Row, Joon;Ryu, Young-Kyu
    • The korean journal of orthodontics
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    • v.26 no.2 s.55
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    • pp.141-151
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    • 1996
  • This study was undertaken to assess the effect of growth on the lips. Not only does lip growth influence the stability of such orthodontic treatment; it also directly influence facial profile, in which the lips have an important part. An understanding of the growth of lips is thus central to a consideration of profile change in orthodontics. By analyzing the serial lateral cephalograms of 15 male and 15 female of 8 years old to 16 yaers old who have normal occlusion. The result of this study were summerized as follows; 1. The largest growth increments in the length of the lips was mod age of 14 in both sexes. 2. The thickness of lips showed lager value for the male than that of the female in the most age group. The lagest growth increments at A point was occured age of 14, while Ls, Li, B point decreased after the age of 10-11. 3. The largest increase in the interval between crest of lower lip and edge of upper incisors was occured between ages 9 and 11 in males. The interval decreased slightly from 8 to 16 years in females. 4. The nasolabial angle decreased slightly from 8 to 16 years in both sexes. 5. The mentolabial angle showed large variation.

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Effect of Joint Orientation Distribution on Hydraulic Behavior of the 2-D DFN System (절리의 방향분포가 이차원 DFN 시스템의 수리적 특성에 미치는 영향)

  • Han, Jisu;Um, Jeong-Gi
    • Economic and Environmental Geology
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    • v.49 no.1
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    • pp.31-41
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    • 2016
  • A program code was developed to calculate block hydraulic conductivity of the 2-D DFN(discrete fracture network) system based on equivalent pipe network, and implemented to examine the effect of joint orientation distribution on the hydraulic characteristics of fractured rock masses through numerical experiments. A rock block of size $32m{\times}32m$ was used to generate the DFN systems using two joint sets with fixed input parameters of joint frequency and gamma distributed joint size, and various normal distributed joint trend. DFN blocks of size $20m{\times}20m$ were selected from center of the $32m{\times}32m$ blocks to avoid boundary effect. Twelve fluid flow directions were chosen every $30^{\circ}$ starting at $0^{\circ}$. The directional block conductivity including the theoretical block conductivity, principal conductivity tensor and average block conductivity were estimated for generated 180 2-D DFN blocks. The effect of joint orientation distribution on block hydraulic conductivity and chance for the equivalent continuum behavior of the 2-D DFN system were found to increase with the decrease of mean intersection angle of the two joint sets. The effect of variability of joint orientation on block hydraulic conductivity could not be ignored for the DFN having low intersection angle between two joint sets.

Evaluation of the Clark Unit Hydrograph Parameters Considering Basin and Meteorologic at Conditions : 1. Selection and Analysis of Representative Storm Events (유역 및 기상상태를 고려한 Clark 단위도의 매개변수 평가: 1. 대표 호우사상의 선정 및 분석)

  • Yoo, Chul-Sang;Kim, Kee-Wook;Lee, Ji-Ho
    • Journal of Korea Water Resources Association
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    • v.40 no.2 s.175
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    • pp.159-170
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    • 2007
  • This study evaluated the parameters of Clark unit hydrograph (UH) estimated using the rainfall-runoff measurements and evaluated their variability. This also includes the quantification of basin and meteorological factors using probability density functions, selection of storm events with mean affecting factors, and derivation of average parameters of the Clark UH from storm events selected. Summarizing the results from this procedure are as follows. (1) It is not easy to avoid much uncertainty on the decision of runoff characteristics (that is, the concentration time and storage coefficient) even with some rainfall-runoff events are available. (2) As the distribution function of concentration time is very skewed, a simple arithmetic mean may lead a biased estimate. That is, the arithmetic mean based on the normal distribution can not be representative anymore. The mode may well be the representative in this case. On the other hand, the storage coefficient shows a symmetric distribution function, so the arithmetic mean may be used use for its representative. For the basin in this study, the concentration time in this study is estimated to be about 7 hours, and the storage coefficient about 22 hours.

Clinical Features of Electrogastrogram in Dyspeptic Patients with Stomach Qi Deficiency (위기허증으로 진단된 소화불량 환자의 임상적 특징; 위전도 검사를 중심으로)

  • Jeong, Hae-in;Kim, Dong-yoon;Baek, So-young;Lee, Ha-nul;Lee, Hyun-jin;Cho, Yun-jae;Ha, Na-yeon;Kim, Jin-sung
    • The Journal of Internal Korean Medicine
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    • v.41 no.3
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    • pp.467-477
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    • 2020
  • Objectives: This study investigated the cutaneous electrogastrogram (EGG) and other clinical characteristics of dyspeptic patients who have been diagnosed with Stomach Qi Deficiency (SQD) using the Scale for Stomach Qi Deficiency (SSQD). Methods: This study reviewed the clinical records of 38 patients with dyspepsia who were evaluated with SSQD and EGG at the Department of Digestive Diseases of Kyung Hee University Korean Medicine Hospital in Seoul, Korea from November 1, 2019 to February 29, 2020. We evaluated the EGG and other clinical characteristics of the SQD patients to determine if there was an association between the SSQD scores and the EGG. Results: In terms of the EGG, the SQD patients showed no significant increase in the percentage of normal slow wave after a meal and a slightly decreased power ratio at Channel 1 and Channel 2. We also found an association between the SSQD scores and the EGG parameters at Channel 1 and Channel 3. The average Ryodoraku score of the patients was 33.00±14.90 (μA). In the Heart Rate Variability (HRV) test, the average Total Power (TP) and Low Frequency/High Frequency (LF/HF)) ratio was 1356.60±13 6.41(ms2) and 1.68±2.25, respectively. Conclusions: The results of this study suggest that clinicians can use Electrogastrography to enhance accuracy when diagnosing the SQD pattern.

Spatial Distribution of Extremely Low Sea-Surface Temperature in the Global Ocean and Analysis of Data Visualization in Earth Science Textbooks (전구 대양의 극저 해수면온도 공간 분포와 지구과학교과서 데이터 시각화 분석)

  • Park, Kyung-Ae;Son, Yu-Mi
    • Journal of the Korean earth science society
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    • v.41 no.6
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    • pp.599-616
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    • 2020
  • Sea-surface temperature (SST) is one of the most important oceanic variables for understanding air-sea interactions, heat flux variations, and oceanic circulation in the global ocean. Extremely low SSTs from 0℃ down to -2℃ should be more important than other normal temperatures because of their notable roles in inducing and regulating global climate and environmental changes. To understand the temporal and spatial variability of such extremely low SSTs in the global ocean, the long-term SST climatology was calculated using the daily SST database of satellites observed for the period from 1982 to 2018. In addition, the locations of regions with extremely low surface temperatures of less than 0℃ and monthly variations of isothermal lines of 0℃ were investigated using World Ocean Atlas (WOA) climatology based on in-situ oceanic measurements. As a result, extremely low temperatures occupied considerable areas in polar regions such as the Arctic Ocean and Antarctic Ocean, and marginal seas at high latitudes. Six earth science textbooks were analyzed to investigate how these extremely low temperatures were visualized. In most textbooks, illustrations of SSTs began not from extremely low temperatures below 0℃ but from a relatively high temperature of 0℃ or higher, which prevented students from understanding of concepts and roles of the low SSTs. As data visualization is one of the key elements of data literacy, illustrations of the textbooks should be improved to ensure that SST data are adequately visualized in the textbooks. This study emphasized that oceanic literacy and data literacy could be cultivated and strengthened simultaneously through visualizations of oceanic big data by using satellite SST data and oceanic in-situ measurements.

Fatty acids composition and lipolysis of Parmigiano Reggiano PDO cheese: effect of the milk cooling temperature at the farm

  • Piero, Franceschi;Paolo, Formaggioni;Milena, Brasca;Giuseppe, Natrella;Michele, Faccia;Massimo, Malacarne;Andrea, Summer
    • Animal Bioscience
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    • v.36 no.1
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    • pp.132-143
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    • 2023
  • Objective: The aim was to study the influence of cooling milk at 9℃ at the farm versus keeping it at 20℃ on Parmigiano Reggiano cheese lipolysis. Methods: A total of six cheesemaking trials (3 in winter and 3 in summer) were performed. In each trial, milk was divided continuously into two identical aliquots, one of which was kept at 9℃ (MC9) and the other at 20℃ (MC20). For each trial and milk temperature, vat milk (V-milk) and the resulting 21 month ripened cheese were analysed. Results: Fat and dry matter and fat/casein ratio were lower in MC9 V-milk (p≤0.05) than in MC20. Total bacteria, mesophilic lactic acid and psychrotrophic and lipolytic bacteria showed significant differences (p≤0.05) between the two V-milks. Regarding cheese, fat content resulted lower and crude protein higher (p≤0.05) both in outer (OZ) and in inner zone (IZ) of the MC9 cheese wheels. Concerning total fatty acids, the MC9 OZ had a lower concentration of butyric, capric (p≤0.05) and medium chain fatty acids (p≤0.05), while the MC9 IZ had lower content of butyric (p≤0.05), caproic (p≤0.01) and short chain fatty acids (p≤0.05). The levels of short chain and medium chain free fatty acids (p≤0.05) were lower and that of long chain fatty acids (p≤0.05) was higher in MC9 OZ cheese. The principal component analysis of total and free fatty acids resulted in a clear separation among samples by seasons, whereas slight differences were observed between the two different milk temperatures. Conclusion: Storing milk at 9℃ at the herd affects the chemical composition of Parmigiano Reggiano, with repercussion on lipolysis. However, the changes are not very relevant, and since the cheese can present a high variability among the different cheese factories, such changes should be considered within the "normal variations" of Parmigiano Reggiano chemical characteristics.

The Recent Climatic Characteristic and Change in the Republic of Korea based on the New Normals (1991~2020) (신평년(1991~2020년)에 기반한 우리나라 최근 기후특성과 변화에 관한 연구)

  • Hongjun Choi;Jeongyong Kim;Youngeun Choi;Inhye Hur;Taemin Lee;Sojung Kim;Sookjoo Min;Doyoung Lee;Dasom Choi;Hyun Min Sung;Jaeil Kwon
    • Atmosphere
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    • v.33 no.5
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    • pp.477-492
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    • 2023
  • Based on the new climate normals (1991~2020), annual mean, maximum and minimum temperature is 12.5℃, 18.2℃, and 7.7℃, respectively while annual precipitation is 1,331.7 mm, the annual mean wind speed is 2.0 m s-1, and the relative humidity is 67.8% in the Republic of Korea. Compared to 1981~2010 normal, annual mean temperature increased by 0.2℃, maximum and minimum temperatures increased by 0.3℃, while the amount of precipitation (0.7%) and relative humidity (1.1%) decreased. There was no distinct change in annual mean wind speed. The spatial range of the annual mean temperature in the new normals is large from 7.1 to 16.9℃. Annual precipitation showed a high regional variability, ranging from 787.3 to 2,030.0 mm. The annual mean relative humidity decreased at most weather stations due to the rise in temperature, and the annual mean wind speed did not show any distinct difference between the new and old normals. With the addition of a warmer decade (2011~2020), temperatures all increased consistently and in particular, the increase in the maximum temperature, which had not significantly changed in previous decades, was evident. The increasing trend of annual and summer precipitation by the 2010s has disappeared in the new normals. Among extreme climate indices, MxT30 (Daily maximum temperature ≥ 33℃ days), MnT25 (Daily minimum temperature ≥ 25℃ days), and PH30 (1 hour maximum precipitation ≥ 30 mm days) increased while MnT-10 (Daily minimum temperature < -10℃ days) and W13.9 (Daily maximum wind speed ≥ 13.9 m/s days) decreased at a statistically significant level. It is thought that a detailed study on the different trends of climate elements and extreme climate indices by region should be conducted in the future.

Effects of Contrast Phases on Automated Measurements of Muscle Quantity and Quality Using CT

  • Dong Wook Kim;Kyung Won Kim;Yousun Ko;Taeyong Park;Jeongjin Lee;Jung Bok Lee;Jiyeon Ha;Hyemin Ahn;Yu Sub Sung;Hong-Kyu Kim
    • Korean Journal of Radiology
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    • v.22 no.11
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    • pp.1909-1917
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    • 2021
  • Objective: Muscle quantity and quality can be measured with an automated system on CT. However, the effects of contrast phases on the muscle measurements have not been established, which we aimed to investigate in this study. Materials and Methods: Muscle quantity was measured according to the skeletal muscle area (SMA) measured by a convolutional neural network-based automated system at the L3 level in 89 subjects undergoing multiphasic abdominal CT comprising unenhanced phase, arterial phase, portal venous phase (PVP), or delayed phase imaging. Muscle quality was analyzed using the mean muscle density and the muscle quality map, which comprises normal and low-attenuation muscle areas (NAMA and LAMA, respectively) based on the muscle attenuation threshold. The SMA, mean muscle density, NAMA, and LAMA were compared between PVP and other phases using paired t tests. Bland-Altman analysis was used to evaluate the inter-phase variability between PVP and other phases. Based on the cutoffs for low muscle quantity and quality, the counts of individuals who scored lower than the cutoff values were compared between PVP and other phases. Results: All indices showed significant differences between PVP and other phases (p < 0.001 for all). The SMA, mean muscle density, and NAMA increased during the later phases, whereas LAMA decreased during the later phases. Bland-Altman analysis showed that the mean differences between PVP and other phases ranged -2.1 to 0.3 cm2 for SMA, -12.0 to 2.6 cm2 for NAMA, and -2.2 to 9.9 cm2 for LAMA.The number of patients who were categorized as low muscle quantity did not significant differ between PVP and other phases (p ≥ 0.5), whereas the number of patients with low muscle quality significantly differed (p ≤ 0.002). Conclusion: SMA was less affected by the contrast phases. However, the muscle quality measurements changed with the contrast phases to greater extents and would require a standardization of the contrast phase for reliable measurement.