• 한국환경독성학회:학술대회논문집
• /
• 한국환경독성학회 2003년도 추계국제학술대회
• /
• pp.170-170
• /
• 2003

An initial study has been conducted with Korea Institute of Geoscience and Mineral resources and National Institute of Environment Research to evaluate the distribution of radon levels and their risk levels of groundwater in Korea. Probability distribution of 616 samples was log-normal one with 1,867pCi/L as arithmetic value, 920pCi/L as median and 40,010pCi/L as maximum during iou. years(1999-2002). In addition, 10% of total samples are in excess of 4,000pCi/L, 20% in excess of 2,700pCi/L, and 30% in excess of 1,700pCi/L, and 15 samples exceeds 10,000pCi/L. Total samples are grouped into 10 areas and 5 rocks unit, and difference of concentrations among areas and rocks are statistically significant(respectively, p<0.0001). The highest area is Daejeon located in ogcheon metamorphic rocks and granitic rocks, and most of all sites with high concentration sites are located in granitic rocks. The lowest area is Jeju located in volcanic rocks. We have estimated excess cancer risks of radon based on these data. To estimate risks, first of all, use patterns of groundwater are categorized with 6 groups: for drinking, household, farming, washing cars, raising stock, and others. We considered risk only for drinking water and household water because radon is rapidly dispersed before it of other use reach human respiratory organs. We select 565 samples for risk analysis, and applied unit risk which is 6.6210-7 per pCi/L to be recommended by NAS committee. Unit risk was derived from considering radon ingestion and radon inhalation from water use. When estimating risk, we analyzed PDF of concentration and represented risk as 50 and 95 percentile values to consider uncertainty with Monte-Carlo simulation. It results in 10-4 level of their excess cancer risk and in 10-2 level in some areas with high concentration of radon. It must be monitor periodically and take adequate actions in these risky sites. We recommend that it needs to take more survey and finally set guideline for radon regulation in groundwater.

• 한국가축번식학회지
• /
• 제22권1호
• /
• pp.67-72
• /
• 1998

Nowadays many kinds of foreign breed horse and Korean native Cheju horse are raised in Korea. Horse has complicated structure and function to maintain normal health, and to overcome severe condition during gallop at full speed. Sometimes the disease take a bad turn becuase of difficulty of correct diagnosis for horse disease. In recent times, horse farm for fattening and reproduction is gradually increasing. However, thoracic disease and abdominal disease are frequently occuring by defect in raising management. But the diagnosis of these kinds of disease is difficult by former diagnostic method. Ultrasonographic diagnostic method is a method to slove the problem. In abroad, nowadays ultrasonography has been reported for circulatory organs and abdomonal organs in horse, cattle, sheep, and dog, and the importance of ultrasonographic diagnosis is recognized in veterinary clinical medicine. In the country, ultrasonography of Korean native goat, cattle and dog was recently reported, but there was no report for the ultrasonography of horse. So, ultrasonogram for the thyroid glands, jugular vein and carotid artery was evaluated in Cheju horse and Thoroughbred horse. Thyroid gland, jugular vein and carotid artery were determined on both sides of neck. The length of right thyroid lobe at the Thoroughbred horse, Thoroughbred foul, Cheju horse and Cheju foul were 54.8, 45.1, 46.1 and 42.2 mm, respectively. The width of right thyroid lobe at the Thoroughbred horse, Thoroughbred foul, Cheju horse and Cheju foul were 18.1, 14.3, 14.6 and 14.2 mm, respectively. The height of right thyroid lobe at the Thoroughbred horse, Thoroughbred foul, Cheju horse and Cheju foul were 27.3, 25.6, 26.2 and 25.5 mm, respectively. Similar ultrasonographic measurements were obtained for the left thyroid gland. The internal diameter of left jugular vein at the Thoroughbred horse, Thoroughbred foul, Cheju horse and Cheju foul were 10.6, 9.7, 10.5 and 9.2 mm, respectively. Similar ultrasonographic measurements were obtained for the right jugular vein. The internal diameter of right carotid artery at the Thoroughbred horse, Thoroughbred foul, Cheju horse and Cheju foul were 9.5, 8.8, 9.1 and 8.5 mm, respectively. Similar ultrasonographic measurements were obtained for the left carotid artery. It is concluded that the ultrasonographic values of this study provides references for the diagnosis of morphologic changes in the thyroid gland, jugular vein and carotid artery in Korean native Cheju horse and Thoroughbred horse.

• 한국대기환경학회:학술대회논문집
• /
• 한국대기환경학회 2001년도 추계학술대회 논문집
• /
• pp.335-335
• /
• 2001

Direct-normal, total horizontal and diffuse horizontal irradiance data obtained from a multi-filter rotating shadowband radiometer over seven different wavelength bands (416nm, 151nm, 616nm, 675nm, 870nm and 940nm and the entire spectrum) has been analyzed at Kwangju, South Korea from June 1998 December 2000. The maximum hourly global radiation flux ranged from 0.44 MJ/$m^2$ to 2.68 MJ/$m^2$ at around 11:00-12:00 Hr local time while the maximum hourly diffuse radiation flux ranged from about 0.96 MJ/$m^2$ to 1.37 MJ/$m^2$. The maximum hourly direct irradiance ranged from 1.42 MJ/$m^2$ to 2.92 MJ/$m^2$ from June1998-2000. During the period under consideration, the average monthly global radiation recorded were 13.09 MJ/$m^2$/day, 10.58MJ/$m^2$/day and 9.78MJ/$m^2$/day for years 1998, 1999 and 2000 respectively, while the diffuse irradiance were 6.54 MJ/$m^2$/day, 5.33 MJ/$m^2$/day and 5.14 MJ/$m^2$/day for f998, 1999 and 2000 respectively. The direct irradiance values at the site were 11.63 MJ/$m^2$/day, 8.24MJ/$m^2$/day and 7.75 MJ/$m^2$/day for 1998, f999 and 2000 respectively. It was observed that each of the years has its own unique meteorological parameters that affect the quality and quantity of radiation received for each month. The annual average daily fractions of the diffuse to the global radiation (KD) were 0.51, 0.61 and 0.59 for years 1998, 1999 and 2000 respectively. Analysis indicated that the average daily KD ranged from 0.13 to a maximum value of 0.99 in May for irradiance measured at the broadband channel while the maximum and minimum KD value of 0.91 and 0.23 was recorded at wavelength band 870nm and 940nm in January and September respectively. The lowest average daily clearness index (Kt) value recorded was 0.03 in May (Spring) and the annual average daily clearness indexes are 0.45, 0.34 and 0.35 for years 1998, f999 and 2000 respectively. The frequency of clear days annually at Kwangju is 67.95%, 29.57% and 40.72% for years 1998, 1999 and 2000 respectively.

• Clinical and Experimental Pediatrics
• /
• 제51권11호
• /
• pp.1236-1240
• /
• 2008

Smith-Lemli-Opitz 증후군은 콜레스테롤 합성 과정의 장애로 발생하는 상염색체 열성으로 유전되는 드문 질환으로 다양한 기형을 동반한다. 이는 DHCR7 유전자 변이로 인한 활성도 저하로 발생하는 질환으로 7DHC, 8DHC의 증가 및 체내 콜레스테롤의 감소에 따른 임상상을 특징으로 한다. 저자들은 국내에서 최초로 SLO 증후군을 유전자 분석을 통하여 진단하였기에 이를 문헌 고찰과 함께 보고하는 바이다.

• 환경영향평가
• /
• 제24권5호
• /
• pp.407-419
• /
• 2015

본 연구는 영산강 수계 1지점과 섬진강 수계 1지점의 논 유출수 4년간 유량과 수질 모니터링 자료를 이용하여 원단위 산정방법에 따른 원단위 차이를 비교하였다. 원단위 산정방법은 실측부하량을 이용한 방법, 국립환경과학원의 새로운 원단위 산정 방법(NIER 방법), EMC 확률분포모형 중앙값을 이용한 방법, 산술평균 EMC와 산술평균 유출율을 이용한 방법을 활용하였다. 원단위 산정방법별 차이를 살펴본 결과 실측부하량을 이용한 방법과 NIER 방법의 원단위는 서로 비슷한 값을 보였지만, 확률분포모형(Lognormal, Gamma)을 이용한 원단위는 상대적으로 작게 나타났다. 한편 산술평균 EMC와 유출율을 이용하여 산정된 원단위는 NIER 방법보다 원단위가 크게 산정되는 것으로 나타났다. 또한 NIER 방법의 원단위는 1995에 조사된 환경부 원단위에 비해 BOD, COD, SS는 큰 값을 T-N은 작은값을, T-P는 비슷한 값을 산정되는 것으로 나타났다.

• 한국환경복원기술학회지
• /
• 제9권5호
• /
• pp.50-59
• /
• 2006

This study was initiated to investigate soil chemical properties under different soil systems. Data such as soil acidity(pH), electrical conductivity(EC), organic matter content(OMC), and cation exchange capacity(CEC) were analyzed with samples from multi-layer, USGA, and mono-layer systems. N, P, K and micronutrients were also measured. Multi-layer system was built up to 60-cm depth with rootzone layer, intermediate layer and two drainage layers. USGA system 45 centimeters deep was constructed with rootzone layer, intermediate layer and drainage layer. Mono-layer system, however, was made only with a 30-cm rootzone layer. Differences were observed in soil pH, EC, OMC, CEC and micronutrients. Soil pH was acceptable for turfgrass growth a year after establishment, being 5.5 to 6.5 in the study. Differences were greatly observed for EC among soil systems. Values of EC for multi-layer, USGA, and mono-layer systems were 39.79, 31.26 and 103.54 uS/em, respectively. The increase rate was approximately 4 to 8 times greater with mono-layer system than those with other two systems. Therefore, it was necessary to avoid micronutrient deficiency such as Fe, Mn etc. through an effective management program in mono-layer system because of its faster potential feasibility of salt accumulation. The greatest OMC was associated with USGA system, being 0.97% which was 11% over that of the other systems. Slight differences were observed for CEC among them. Mono-layer system produced 1.45 me/100g, 10.3% and 8.9% lower in CEC than those of multi-layer and USGA system, respectively. Micronutrients such as Fe, Zn, and Mn etc. were below the level required for turf growth, regardless of soil systems. It was considered that one year after turf establishment was not enough to build up micronutrients in sand-based soil systems to the normal level for a turf growth. These results demonstrate that intensive management program including grow-in concept fertilization should be integrated into sand-based soil systems, even after a year in establishment. Regular nutrient monitoring by soil analyses is a strong necessity to decide the kinds and amount of fertilizer. Also, strategic management program must be selectively employed according to sports turf soil systems.

• 대한방사선기술학회지:방사선기술과학
• /
• 제40권3호
• /
• pp.453-460
• /
• 2017

의료방사선 방호용 앞치마의 새로운 정성적인 평가방법을 개발하여 효과적인 정도관리 및 보수 관리법을 제시하고자 한다. 임상에서 사용되고 있는 0.45 mm Pb 앞치마 100개를 대상으로 관전압 75 kVp, 관전류 12.5 mAs의 방사선 조사조건으로 영상을 획득하였고, 동일한 조건으로 0.45 mm 납판을 대상으로 비교하였다. 획득된 영상은 Image J 프로그램을 이용하여 최대 신호 대 잡음 비(Pick Signal-to-Noise Ratio; PSNR) 값을 비교하였다. PSNR은 납판의 이미지와 상이한 앞치마(11dB 미만)는 40개, 유사한 앞치마(11dB 이상, 30dB 미만)는 55개, 거의 동일한(30dB 이상) 앞치마는 5개였다. 또한 선량은 앞치마에 대해서 정규분포를 나타냈으며, PSNR이 11dB 미만, 30dB 이상인 앞치마를 각 5개씩 선정한 후 8구역으로 나누어 비교분석한 결과 두 그룹은 통계적으로 유의하였다. 결론적으로, Image J 프로그램을 통해 획득한 PSNR 값은 앞치마의 정도관리 및 정기적인 성능평가가 가능한 정도관리 및 보수 관리법으로 적용 가능할 것으로 판단된다.

• Toxicological Research
• /
• 제34권3호
• /
• pp.221-229
• /
• 2018

Tenofovir nanoparticles are novel therapeutic intervention in human immunodeficiency virus (HIV) infection reaching the virus in their sanctuary sites. However, there has been no systemic toxicity testing of this formulation despite global concerns on the safety of nano drugs. Therefore, this study was designed to investigate the toxicity of Tenofovir nanoparticle (NTDF) on the liver and kidney using an animal model. Fifteen adult male Sprague-Dawley (SD) rats maintained at the animal house of the biomedical resources unit of the University of KwaZulu-Natal were weighed and divided into three groups. Control animals (A) were administered with normal saline (NS). The therapeutic doses of Tenofovir (TDF) and nanoparticles of Tenofovir (NTDF) were administered to group B and C and observed for signs of stress for four weeks after which animals were weighed and sacrificed. Liver and kidney were removed and fixed in formal saline, processed and stained using H/E, PAS and MT stains for light microscopy. Serum was obtained for renal function test (RFT) and liver function test (LFT). Cellular measurements and capturing were done using ImageJ and Leica software 2.0. Data were analysed using graph pad 6, p values < 0.05 were significant. We observed no signs of behavioural toxicity and no mortality during this study, however, in the kidneys, we reported mild morphological perturbations widening of Bowman's space, and vacuolations in glomerulus and tubules of TDF and NTDF animals. Also, there was a significant elevation of glycogen deposition in NTDF and TDF animals when compared with control. In the liver, there were mild histological changes with widening of sinusoidal spaces, vacuolations in hepatocytes and elevation of glycogen deposition in TDF and NTDF administered animals. In addition to this, there were no significant differences in stereological measurements and cell count, LFT, RFT, weight changes and organo-somatic index between treatment groups and control. In conclusion, NTDF and TDF in therapeutic doses can lead to mild hepatic and renal histological damage. Further studies are needed to understand the precise genetic mechanism.

• 한국잡초학회지
• /
• 제31권3호
• /
• pp.289-293
• /
• 2011

본 연구는 벼에 대한 피, 자귀풀과 미국가막사리의 경합에 따른 수량피해 예측과 경제적인 잡초관리를 위한 방제필요 밀도를 구명하고자 하였다. 수원과 대구지역에서 얻어진 성적을 종합한 예측모델식에 따르면 논에서 피, 자귀풀, 미국가막사리가 완전히 방제되었을 때의 쌀수량은 각각 5.5t, 5.5t, 5.4t 으로 예측되었다. 초종별 평방미터당 요방제 필요밀도는 자귀풀은 제초제 종류별로 0.5~0.7본, 피는 1.2~1.4본, 미국가막사리는 1.6~1.9본인 것으로 예측되었다.

• 한국식품과학회지
• /
• 제41권3호
• /
• pp.231-237
• /
• 2009

팜유와 아보카도유를 이용하여 효소적 방법을 통해 trans free margarine stock(TFMS)을 제조하였다. 회분식 반응기(stirred batch type reactor)를 통한 본 반응은 sn-1,3 위치 특이성을 가진 lipozyme RM IM(from Rhizomucor miehei)을 사용하였다. 반응기질 대두극도경화유와 아보카도유 및 팜유는 30:150:120(g)의 비율로 230 rpm, $65^{\circ}C$에서 합성하였으며 이를 통해 이화학적 특성을 분석하였다. 재구성 지질의 DSC 분석 결과 TFMS의 solid fat content(SFC)는 $5^{\circ}C$에서 58.6%, $35^{\circ}C$에서의 약 8.5%로 확인 되었으며 7.3, 23.6, $35.3^{\circ}C$의 DSC 상의 melting point 특성을 나타내었다. TFMS는 C16:0(약 29%)과 C18:1(약 45%)이 주요 지방산으로 확인되었고 ${\Sigma}SFA$는 40.7%이었으며 trans 지방산은 검출되지 않았다. Sn-2 위치에는 주요적으로 C16:0(21.6%)과 C18:1(50.2%)의 지방산 조성이 확인되었다. RP-HPLC를 통해 TFMS를 이루고 있는 TAG의 PN을 확인 하였다. 주요적으로 PN=48이 대부분을 차지하였고 PN=46, PN=50으로 분리되었으며 TFMS의 반응 전과 비교 시 차별적인 TAG peak를 확인할 수 있었다. 한편, ${\alpha}-$, ${\gamma}-$ 및 ${\delta}$-tocopherol이 각각 5.7, 2.1, 1.7 mg/100 g을 나타냈으며 산가, 요오드가, 비누화가를 통해 TFMS의 이화학적 특성을 확인 할 수 있었다. TFMS를 통해 마가린 제조 시 물성 변화를 고려하여 마가린의 적합한 물성을 지닐 수 있을 것이라 사료된다.