• 대한추나의학회지
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• 제1권1호
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• pp.45-53
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• 2000

Objectives : CHUNA therapy that removes compression of dislocated vertebral bones has positive effect, but sometimes improper CHUNA manual therapy may give rise to negative effect. The aim of this study is to make sure that cervical CHUNA manual therapy give positive effect or negative effect to the blood flow velocity of vertebral artery(VA) and basilar artery(BA) by Trancranial Doppler sonography(TCD). Methods : We performed TCD study on 20patients(male 5, female 15, mean ages 38.5 years) with diagnosis like cervical movement related disorder, headache or dizziness. After we measured mean blood flow velocity(Vm) of VA and BA before cervical CHUNA therapy(Pre-CCT) and after cervical CHUNA therapy(Post-CCT), statistically evaluated the results. Results: The patients received cervical CHUNA therapy for TA sequel, HIVD of cervical spine, headache, dizziness, neck stiffness etc. VA Vm was $31.9{\pm}8.0cm/sec$ before CHUNA therapy, but significantly increased $35.0{\pm}8.7cm/sec$ after CHUNA therapy (p < 0.05). But, there was no significant variation of BA Vm between $41.8{\pm}7.5cm/sec$ Pre-CCT and $41.2{\pm}8.5cm/sec$ Post-CCT(p>0.05). Though VA Vm slightly increased after CHUNA therapy in normal range group, there was no significant variation between VA Vm Pre-CCT and VA Vm Post~CCT. In VA Vm decrease group, VA Vm significantly increased after CHUNA therapy(p<0.05). But, there was no significant variation of BA Vm between Pre-CCT and Post-CCT in BA Vm normal range group and BA Vm decrease group(p>0.05). Conclusions: These findings suggest that cervical CHUNA manual therapy have positive effect on blood flow velocity of VA and BA.

• 전기전자학회논문지
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• 제11권3호
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• pp.108-116
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• 2007

This paper proposed an analyzable parameter and its analytic method to provide more accurate information than currently employed 4 channels system which uses pulse wave velocity (PWV) information of the volume pulse wave measured from 4 arterial channels for the characterization of arterial vessel. In order to verify the volume pulse waves on 4 sites were simultaneously acquired subjects aged from 12 to 81 years old. and the proposed parameters were extracted from time (UT) was then compared with blood pressure. Then, the regression analyses were done relationships among the proposed parameter and others, such as aging, pulse transit time pressure (BP). The followings are the results of linear regression analysis of the proposed parameter for total 50 normal subjects. We selected any two subjects (58 years and 27 years) and measured PPG (photoplethysmogram) and BP of before and after exercise. The coefficient of correlations between BP and UT observed was -0.928 for 50 years subject, and -0.922 for 20 years subject. For total 50 normal subjects, in case of correlation between the pulse transit time and BP, the result showed -0.170 on left side and -0.233 on right side, and the coefficient value of correlation between the pulse transit time and UT was -0.607 on left side and -0.510 on right side. UI is strongly correlated with the pulse transit time than BP. Hence, we believe that the proposed parameter is related with the index of arterial stiffness.

• 한국구조물진단유지관리공학회 논문집
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• 제16권3호
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• pp.99-108
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• 2012

본 연구에서는 철근콘크리트 슬래브의 내부식성과 경량화를 도모하기 위하여 GFRP bar를 휨보강근으로 사용하는 경량골재콘크리트 슬래브를 고려하고 이 구조물에 대하여 기초적인 거동을 조사하였다. 경량콘크리트의 압축강도 및 인장강도 그리고 콘크리트 파괴에너지 측정, 일련의 슬래브 휨실험, 비선형유한요소해석을 통한 수치해석, 휨실험과 수치해석의 결과비교 등이 행하여졌다. 그 결과, GFRP bar를 휨보강근으로 사용한 경량콘크리트 슬래브는 기준시험체로 사용된 동일 규격의 철근콘크리트 슬래브에 비하여 무게를 28%정도 감소시킬 수 있었지만 파괴하중은 36%정도 감소되었다. 이는 GFRP bar의 낮은 축강성과 경량콘크리트의 낮은 부착강도 때문인 것으로 판단된다. 그리고 경량콘크리트의 부착력 감소 특성을 고려하기 위하여 GFRP bar와 콘크리트 경계면 사이에 계면요소를 사용한 수치해석 결과는 계면요소의 사용이 실험결과에 더 근접해갈 수 있는 방법임을 보여주었다.

• Steel and Composite Structures
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• 제31권6호
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• pp.541-558
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• 2019

In Special Concentrically Braced Frames (SCBFs), vertical and horizontal components of the brace force must be resisted by column and beam, respectively but normal force component existing at the gusset plate-to-column and beam interfaces, creates out-of-plane action making distortion in column and beam faces adjacent to the gusset plate. It is a main concern in Hollow Structural Section (HSS) columns and beams where their webs and gusset plate are not in the same plane. In this paper, a new gusset plate passing through the HSS columns and beams, named as through gusset plate, is proposed to study the force transfer mechanism in such gusset plates of SCBFs compared to the case with conventional gusset plates. For this purpose, twelve SCBFs with diagonal brace and HSS columns and twelve SCBFs with chevron brace and HSS columns and beams are considered. For each frame, two cases are considered, one with through gusset plates and the other with conventional ones. Based on numerical results, using through gusset plates prevents distortion and out-of-plane deformation at HSS column and beam faces adjacent to the gusset plate helping the entire column and beam cross-sections to resist respectively vertical and horizontal components of the brace force. Moreover, its application increases energy dissipation, lateral stiffness and strength around 28%, 40% and 32%, respectively, improving connection behavior and raising the resistance of the normal force components at the gusset plate-to-HSS column and beam interfaces to approximately 4 and 3.5 times, respectively. Finally, using such through gusset plates leads to better structural performance particularly for HSS columns and beams with larger width-to-thickness ratio elements.

• Asian-Australasian Journal of Animal Sciences
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• 제32권6호
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• pp.896-903
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• 2019

Objective: Qianbei-Pockmarked goats are affected by a disorder locally referred to as 'Ruanguzheng Disorder', which is characterized by emaciation, lameness, muscular relaxation, stiffness of the extremities, and abnormal curvatures of the long bones. Our objective was to determine the relationship between the disorder and phosphorus deficiency. Methods: Tissue samples were collected from affected and healthy animals, while soil and herbage samples were collected from affected and healthy pastures. Biochemical parameters were determined using an automatic biochemical analyzer (OLYMPUS AU 640, Olympus Optical Co., Tokyo, Japan). Mineral contents in soil, forage, and tissue were determined using a Perkin-Elmer AAS5000 atomic absorption spectrophotometer (Perkin-Elmer, Norwalk, CT, USA). Results: The results showed that phosphorus contents in herbages from affected pastures were markedly lower than those from healthy areas (p<0.01), and the ratio of calcium to phosphorus in the affected herbages was 12.93:1. The phosphorus contents of wool, blood, tooth, and bone from affected animals were also markedly lower than those from healthy animals (p<0.01). Serum phosphorus values in affected animals were much lower than those in healthy animals, while serum alkaline phosphatase values from affected animals were markedly higher than those from healthy animals (p<0.01). Inorganic phosphorus values from affected animals were approximately half of that in the control group. Supplementation of disodium hydrogen phosphate prevented and cured the disorder. Conclusion: This study demonstrates that Ruanguzheng disorder in Qianbei-Pockmarked goats is primarily caused by phosphorus deficiencies in herbage due to fenced pastures and natural habitat fragmentation.

• Tribology and Lubricants
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• 제40권4호
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• pp.133-138
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• 2024

This study evaluates the structural safety of wind turbine blades, analyzes the behavior of composite laminate structures with and without defects, and assesses surface erosion wear. The NREL 5 MW standard is applied to assign accurate composite material properties to each blade section. Modeling and analysis of the wind turbine blades reveal stable behavior under individual load conditions (gravity, motor speed, wind speed), with the web bearing most of the load. Surface erosion wear analysis in which microparticle impacts are simulated on the blade coating shows a maximum stress and maximum displacement of 14 MPa and 0.02 mm, respectively, indicating good initial durability, but suggest potential long-term performance issues due to cumulative effects. The study examines defect effects on composite laminate structures to compare the stress distribution, strain, and stiffness characteristics between normal and cracked states. Although normal conditions exhibit stable behavior, crack defects lead to fiber breakage, high-stress concentration in the vulnerable resin layer, and decreased rigidity. This demonstrates that local defects can compromise the safety of the entire structure. The study utilizes finite element analysis to simulate various load scenarios and defect conditions. Results show that even minor defects can significantly alter stress distributions and potentially lead to catastrophic failure if left unaddressed. These findings provide valuable insights for wind turbine blade safety evaluations, surface protection strategies, and composite structure health management. The methodology and results can inform the design improvements, maintenance strategies, and defect detection techniques of the wind energy industry.

• Asian Pacific Journal of Cancer Prevention
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• 제16권5호
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• pp.1789-1794
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• 2015

Background: Non-alcoholic fatty liver disease (NAFLD), the most common liver problem in diabetes, is a risk factor for liver cancer. Diabetes, high body mass index (BMI) and old age can all contribute to NAFLD progression. Transient elastography (TE) is used for non-invasive fibrosis assessment. Objectives: To identify the prevalence of NAFLD and significant hepatic fibrosis in diabetic patients and to assess associated factors. Materials and Methods: One hundred and forty-one diabetic and 60 normal subjects were screened. Fatty liver was diagnosed when increased hepatic echogenicity and vascular blunting were detected by ultrasonography. Liver stiffness measurement (LSM) representing hepatic fibrosis was assessed by TE. LSM ${\geq}7$ kPa was used to define significant hepatic fibrosis. Results: Four cases were excluded due to positive hepatitis B viral markers and failed TE. Diabetic patients had higher BMI, systolic blood pressure, waist circumference and fasting glucose levels than normal subjects. Fatty liver was diagnosed in 82 (60.7%) diabetic patients but in none of the normal group. BMI (OR: 1.31; 95%CI: 1.02-1.69; p=0.038) and alanine aminotransferase (ALT)(OR: 1.14; 95%CI: 1.05-1.23; p=0.002) were associated with NAFLD. Diabetic patients with NAFLD had higher LSM than those without [5.99 (2.4) vs 4.76 (2.7) kPa, p=0.005)]. Significant hepatic fibrosis was more common in diabetic patients than in normal subjects [22 (16.1%) vs 1 (1.7%), p=0.002]. Aspartate aminotransferase (AST)(OR: 1.24; 95%CI: 1.07-1.42; p=0.003) was associated with significant hepatic fibrosis. Conclusions: Sixty and sixteen percent of diabetic patients were found to have NAFLD and significant hepatic fibrosis. High BMI and ALT levels are the predictors of NAFLD, and elevated AST level is associated with significant hepatic fibrosis.

• 대한간학회지
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• 제24권4호
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• pp.384-391
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• 2018

Backgrounds/Aims: The objective of our study was to determine the epidemiological, laboratory, and serological characteristics of patients with chronic hepatitis B virus (HBV) infection and normal transaminases. The study also aimed to evaluate liver damage by measuring the liver fibrosis (LF) grade and to identify possible factors associated with the presence of fibrosis. Methods: A retrospective observational study was conducted in patients with chronic HBV infection and classified as inactive carriers or immune-tolerant. Epidemiological variables of age, sex, immigrant, alcohol consumption, and body mass index (BMI), as well as virological variables (HBV DNA) and transaminase level were collected throughout the follow-up. The LF grade was evaluated by transient elastography. The cutoff value for significant fibrosis (SF) was liver stiffness ${\geq}7.9kPa$. Results: A total of 214 patients were included in the analysis, and 62% of them had a BMI ${\geq}25kg/m^2$. During follow-up, 4% of patients showed transaminase elevation (<1.5 times normal). Most patients had a viral DNA level <2,000 IU/mL (83%). Data on LF were available in 160 patients; of these, 14% had SF, 9% F3, and 6% F4. The variables associated with the presence of SF were transaminase alteration during follow-up, as 23% of patients with SF had elevated transaminases versus 3% of patients without SF (P<0.005), and BMI, as the vast majority of patients with SF (88%) had a BMI ${\geq}25kg/m^2$ versus 56% of patients without SF (P<0.05). Conclusions: In patients with chronic HBV infection and normal transaminases, liver damage does not seem to be related to DNA levels, alcohol consumption, or immigrant status. SF seems to be associated with transaminase alteration during follow-up and elevated BMI. It is therefore recommended to measure LF grade with validated non-invasive methods in such patients.

• Interaction and multiscale mechanics
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• 제4권4호
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• pp.257-271
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• 2011

The analysis of interfacial stresses in structural component has been the subject of several investigations but it still requires more effort and studies. In this study a general three-dimensional interface element has been formulated for stress and displacement analyses in the interfacial area between two adjacent plate bending element and brick element. Interface element has 16 nodes with 5 degrees of freedom (DOF) in each node adjacent to plate bending element and 3 DOF in each node adjacent to brick element. The interface element has ability to transfer three translations from each side of interface element and two rotations in the side adjacent to the plate element. Stiffness matrix of this element was formulated and implemented in three-dimensional finite element code. Application of this element to the reinforced concrete (RC) beam strengthened with fiber reinforced polymer (FRP) including variation of deflection, slip between plate and concrete, normal and shear stresses distributions in FRP plates have been verified using experimental and numerical work of strengthened RC beams carried out by some researchers. The results show that this interface element is effective and can be used for structural component with these types of interface elements.

• Steel and Composite Structures
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• 제24권2호
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• pp.177-189
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• 2017

Hybrid-fiber reinforced concrete (HFRC) may provide much higher tensile and flexural strengths, tensile ductility, and flexural toughness than normal concrete (NC). HFRC slab has outstanding advantages for use as a composite bridge potential deck slab owing to higher tensile strength, ductility and crack resistance. However, there is little information on shear connector associated with HFRC slabs. To investigate the mechanical behavior of the stud shear connectors embedded in HFRC slab, 14 push-out tests (five batches) in HFRC and NC were conducted. It was found that the stud shear connector embedded in HFRC had a better ductility, higher stiffness and a slightly larger shear bearing capacity than those in NC. The experimentally obtained ultimate resistances of the stud shear connectors were also compared against the equations provided by GB50017 2003, ACI 318-112011, AISC 2011, AASHTO LRFD 2010, PCI 2004, and EN 1994-1-1 (2004), and an empirical equation to predict the ultimate shear connector resistance considering the effect of the HFRC slabs was proposed and validated by the experimental data. Curve fitting was performed to find fitting parameters for all tested specimens and idealized load-slip models were obtained for the specimens with HFRC slabs.