• Title/Summary/Keyword: Normal response

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An Experimental Study on Characteristics of Sprinkler Head Activation in Low Growth Rate Fire (저성장속도 화재에서의 스프링클러 헤드 동작특성에 관한 실험적 연구)

  • Choi, Yong-Seob;Yoon, Jong-Chil
    • Fire Science and Engineering
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    • v.30 no.5
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    • pp.26-35
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    • 2016
  • Sprinkler installations shall be operated at normal operating temperature of the atmosphere as a fire sprinkler head in any facility to control and extinguish the fire when the fire initially. Recently, however, some flush type quick response automatic sprinkler heads in slow fire place is a problem that can not be normal operation are raised. In this paper, by using the experimental model of the Apartment house of Commons and Cabinet burner size bedrooms fire conditions to form a slow growth rate and can supply more than 0.2 MPa pressure is the minimum pressure that can be applied inside the pipe in the field experiment was conducted. In the majority of experiments lush type quick response automatic sprinkler heads which is used in the country it was confirmed to be incompletely opened as the Cold Soldering occur. This phenomenon is likely to fail early fire suppression and control because they can cause the spread of fire and casualties needed to complement domestic product testing and type approval standards through additional research.

The Effect of Cooking Form of Rice and Barley on the Postprandial Serum Glucose and Insulin Responses in Normal Subject (조리형태를 달리한 쌀과 보리의 급여가 정상인의 혈당과 인슐린치에 미치는 영향)

  • 임상선;김미혜;승정자;이종호
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.20 no.4
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    • pp.293-299
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    • 1991
  • To investigate the effect of cooking form of rice and barley on postprandial serum glucose and insulin response in normal subject, five test carbohydrates calculated to contain 50g of glucose were consumed. Oral ingestions were divided into 5 group, i. e. dextrose(control), ground white rice, ground barley, whole white rice, whole barley, Postprandial glucose and insulin responses were measured over 3hr and showed the following pattern. Dextrose and ground white rice elicited similar postprandial serum glucose and insulin responses whereas ground barley and whole white rice intemediate, whole barley gave the lowest responses in the test group. The ground form of rice and barley were significantly higher responses than the unground form of those as well as whole white rice were higher responses whole barley, The results suggested that the cooking form of rice and barley was an important determinant of the postprandial metabolic responses.

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Immunological Studies on the Antitumor Componets of the Basidiocarps of Agrocybe cylindracea

  • Kim, Byong-Kak;Hyun, Jin-won;Yoon, Jong-Myung;Choi, Eung-Chil
    • Archives of Pharmacal Research
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    • v.20 no.2
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    • pp.128-137
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    • 1997
  • The effects of cylindan, a polysaccharide isolated from the basidiocarps of Agrocybe cylindracea, on murine sarcoma 180 tumor and murine immune cells were examined after intraperitoneal administration. Cylindan exhibited a marked life extension effect in mice against ascite forms of sarcoma 180 and Lewis lung carcinoma at a dose of 50 mg/kg/day, although it did not show any direct cytotoxicity against sarcoma 180, X5563, and MM46 murine tumor cells. Cylindan increased numbers of bone marrow stem cells as well as peritoneal exudate cells in flow cytometry using monoclonal antibodies. The tumor bearing mice group apparently showed the increase of macrophages and cytotoxic T lymphocytes in mouse spleen cells during the early stage of tumor growth. But during the later stage, the control group decreased immune cells and cylindan restored the decreased immune cells in the tumor bearing mice to the normal level. In non-specific immune response, cylindan stimulated the bacterial phagocytosis and acid phosphatase production in macrophages. It also activated components of the alternative complement pathway and natural killer activity against YAC-1 lymphoma. In number of plasma cells as token of stimulation of the differentiation of B lymphocytes. In cellular immunity, cylindan restored the depressed response of delayed type hypersensitivity in the tumor bearing mice to 60% of the normal level and increased the interleukin-2 (IL-2) responsiveness in the IL-2 dependent CTLL-2 cells. These results suggest that cylindan did not show direct cytotoxic effects on tumor cells but restored the decreased immune response of the tumor bearing mice.

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The influence of the initial strains of the highly elastic plate on the forced vibration of the hydro-elastic system consisting of this plate, compressible viscous fluid, and rigid wall

  • Akbarov, Surkay D.;Ismailov, Meftun I.;Aliyev, Soltan A.
    • Coupled systems mechanics
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    • v.6 no.4
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    • pp.439-464
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    • 2017
  • The hydro-elastic system consisting of a pre-stretched highly elastic plate, compressible Newtonian viscous fluid, and the rigid wall is considered and it is assumed that on the plate a lineal-located time-harmonic force acts. It is required to investigate the dynamic behavior of this system and determine how the problem parameters and especially the pre-straining of the plate acts on this behavior. The elasticity relations of the plate are described through the harmonic potential and linearized (with respect to perturbations caused by external time-harmonic force) form of these relations is used in the present investigation. The plane-strain state in the plate is considered and the motion of that is described within the scope of the three-dimensional linearized equations of elastic waves in elastic bodies with initial stresses. The motion of the fluid is described by the linearized Navier-Stokes equations and it is considered the plane-parallel flow of this fluid. The Fourier transform with respect to the space coordinate is applied for a solution to the corresponding boundary-value problem. Numerical results on the frequency response of the interface normal stress and normal velocity and the influence of the initial stretching of the plate on this response are presented and discussed. In particular, it is established that the initial stretching of the plate can decrease significantly the absolute values of the aforementioned quantities.

Distorted Bounding Surface of Clay with Consideration of the Effect of Temperature on Shearing Response (전단시 온도 영향을 고려한 점성토의 왜곡 경계면 모델 개발)

  • Woo, Sang Inn;Yune, Chan-Young
    • Journal of the Korean Geotechnical Society
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    • v.36 no.12
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    • pp.117-124
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    • 2020
  • The present research focuses on a methodology to describe shearing response of clay with respect to temperature. An increase of temperature shifts the normal consolidation line to move down in the plane of void ratio and mean effective stress. The critical state line, however, does not move as much as the normal consolidation line in accordance with temperature increase. As temperature increase, therefore, the difference between the critical state mean effective stress and the pre-consolidation pressure reduces. To reflect this easily, the present study applies a bounding surface consisting of two parts divided by the critical state mean effective stress. This study calibrated a bounding surface for the soft Bangkok clay and performed elemental simulation for undrained triaxial compression tests. The elemental simulation showed that the model can describe the mechanical response upon temperature of clay without complex hardening and evolution rules compared to the experimental data.

Influence of Stimulus Polarity on the Auditory Brainstem Response From Level-Specific Chirp

  • Dzulkarnain, Ahmad Aidil Arafat;Salamat, Sabrina;Shahrudin, Fatin Amira;Jamal, Fatin Nabilah;Zakaria, Mohd Normani
    • Journal of Audiology & Otology
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    • v.25 no.4
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    • pp.199-208
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    • 2021
  • Background and Objectives: No known studies have investigated the influence of stimulus polarity on the Auditory Brainstem Response (ABR) elicited from level-specific (LS) chirp. This study is important as it provides a better understanding of the stimulus polarity selection for ABR elicited from LS chirp stimulus. We explored the influence of stimulus polarity on the ABR from LS chirp compared to the ABR from click at 80 dBnHL in normal-hearing adults. Subjects and Methods: Nineteen adults with normal hearing participated. The ABRs were acquired using click and LS chirp stimuli using three stimulus polarities (rarefaction, condensation, and alternating) at 80 dBnHL. The ABRs were tested only on the right ear at a stimulus rate of 33.33 Hz. The ABR test was stopped when the recording reached the residual noise level of 0.04 μV. The ABRs amplitudes, absolute latencies, inter-peak latencies (IPLs), and the recorded number of averages were statistically compared among ABRs at different stimulus polarities and stimuli combinations. Results: Rarefaction polarity had the largest ABR amplitudes and SNRs compared with other stimulus polarities in both stimuli. There were marginal differences in the absolute latencies and IPLs among stimulus polarities. No significant difference in the number of averages required to reach the stopping criteria was found. Conclusions: Stimulus polarities have a significant influence on the ABR to LS chirp. Rarefaction polarity is recommended for clinical use because of its larger ABR peak I, III, and V amplitudes than those of the other stimulus polarities.

Seismic loading response of piled systems on soft soils - Influence of the Rayleigh damping

  • Jimenez, Guillermo A. Lopez;Dias, Daniel;Jenck, Orianne
    • Geomechanics and Engineering
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    • v.29 no.2
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    • pp.155-170
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    • 2022
  • An accurate analysis of structures supported on soft soils and subjected to seismic loading requires the consideration of the soil-foundation-structure interaction. An important aspect of this interaction lies with the energy dissipation due to soil material damping. Unlike advanced constitutive models that can induce energy loss, the use of simple elastoplastic constitutive models requires additional damping. The frequency dependent Rayleigh damping is a formulation that is frequently used in dynamic analysis. The main concern of this formulation is the correct selection of the target damping ratio and the frequency range where the response is frequency independent. The objective of this study is to investigate the effects of the Rayleigh damping parameters in soil-pile-structure and soil-inclusion-platform-structure systems in the presence of soft soil under seismic loading. Three-dimensional analyses of both systems are carried out using the finite difference software Flac3D. Different values of target damping ratios and minimum frequencies are utilized. Several earthquakes are used to study the influence of different excitation frequencies in the systems. The soil response in terms of accelerations, displacements and strains is obtained. For the rigid elements, the results are presented in terms of bending moments and normal forces. The results show that when the frequency of the input motion is close to the minimum (central) frequency in the Rayleigh damping formulation, the overdamping amount is reduced, and the surface spectral acceleration of the analyzed pile and inclusion systems increases. Thus, the bending moments and normal forces throughout the piles and inclusions also increase.

Influence of Stimulus Polarity on the Auditory Brainstem Response From Level-Specific Chirp

  • Dzulkarnain, Ahmad Aidil Arafat;Salamat, Sabrina;Shahrudin, Fatin Amira;Jamal, Fatin Nabilah;Zakaria, Mohd Normani
    • Korean Journal of Audiology
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    • v.25 no.4
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    • pp.199-208
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    • 2021
  • Background and Objectives: No known studies have investigated the influence of stimulus polarity on the Auditory Brainstem Response (ABR) elicited from level-specific (LS) chirp. This study is important as it provides a better understanding of the stimulus polarity selection for ABR elicited from LS chirp stimulus. We explored the influence of stimulus polarity on the ABR from LS chirp compared to the ABR from click at 80 dBnHL in normal-hearing adults. Subjects and Methods: Nineteen adults with normal hearing participated. The ABRs were acquired using click and LS chirp stimuli using three stimulus polarities (rarefaction, condensation, and alternating) at 80 dBnHL. The ABRs were tested only on the right ear at a stimulus rate of 33.33 Hz. The ABR test was stopped when the recording reached the residual noise level of 0.04 μV. The ABRs amplitudes, absolute latencies, inter-peak latencies (IPLs), and the recorded number of averages were statistically compared among ABRs at different stimulus polarities and stimuli combinations. Results: Rarefaction polarity had the largest ABR amplitudes and SNRs compared with other stimulus polarities in both stimuli. There were marginal differences in the absolute latencies and IPLs among stimulus polarities. No significant difference in the number of averages required to reach the stopping criteria was found. Conclusions: Stimulus polarities have a significant influence on the ABR to LS chirp. Rarefaction polarity is recommended for clinical use because of its larger ABR peak I, III, and V amplitudes than those of the other stimulus polarities.

Fragility assessment of buckling-restrained braced frames under near-field earthquakes

  • Ghowsi, Ahmad F.;Sahoo, Dipti R.
    • Steel and Composite Structures
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    • v.19 no.1
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    • pp.173-190
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    • 2015
  • This study presents an analytical investigation on the seismic response of a medium-rise buckling-restrained braced frame (BRBF) under the near-fault ground motions. A seven-story BRBF is designed as per the current code provisions for five different combinations of brace configurations and beam-column connections. Two types of brace configurations (i.e., Chevron and Double-X) are considered along with a combination of the moment-resisting and the non-moment-resisting beam-to-column connections for the study frame. Nonlinear dynamic analyses are carried out for all study frames for an ensemble of forty SAC near-fault ground motions. The main parameters evaluated are the interstory and residual drift response, brace displacement ductility, and plastic hinge mechanisms. Fragility curves are developed using log-normal probability density functions for all study frames considering the interstory drift ratio and residual drift ratio as the damage parameters. The average interstory drift response of BRBFs with Double-X brace configurations significantly exceeded the allowable drift limit of 2%. The maximum displacement ductility characteristics of BRBs is efficiently utilized under the seismic loading if these braces are arranged in the Double-X configurations instead of Chevron configurations in BRBFs located in the near-fault regions. However, BRBFs with the Double-X brace configurations exhibit the higher interstory drift and residual drift response under near-fault ground motions due to the formation of plastic hinges in the columns and beams at the intermediate story levels.

Two Cases of Non-Small Cell Lung Cancer Treated with Intravenous Cultivated Wild Ginseng Pharmacopuncture (산삼약침 혈맥주입을 시행한 비소세포성폐암 환자 2례)

  • Bang, Sun-Hwi;Kwon, Ki-Rok;Yoo, Hwa-Seung
    • Journal of Pharmacopuncture
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    • v.11 no.2
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    • pp.13-19
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    • 2008
  • Objectives To investigate the therapeutic effects of intravenous cultivated wild ginseng(Panax ginseng C.A. Meyer) pharmacopuncture(CWGP) in treating patients with non-small cell lung cancer(NSCLC). Design Prospective case series. Setting This study was conducted at the East-West Cancer Center of Dunsan Oriental Hospital, Daejeon University. Patients Two non-small cell lung cancer patients. Intervention Two non-small cell lung cancer patients were injected CWGP(20mL/day) mixed with 0.9% normal saline(100mL) intravenously. Each patient received a total of 16 and 9 cycles, respectively. One cycle is composed of 14 days. Outcome Measures The effect of intravenous CWGP was measured by scanning with computed tomography(CT) after every 2 cycle and Positron emission tomography- computed tomography(PET/CT) after every 6 cycles. Response and progression was evaluated using the Response Evaluation Criteria in Solid Tumors(RECIST) Committee classification of complete response(CR), partial response(PR), progressive disease(PD) and stable disease(SD). Results They were treated with intravenous CWGP for 8 and 5 months respectively. time later, each tumor remains stable disease(SD). Conclusion These cases may give us a possibility that intravenous CWGP offers potential benefits for non-small cell lung cancer patients.