• Title/Summary/Keyword: Normal polarity

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Effect of Azadirachta indica flower extract on basal and experimentally elevated blood glucose in rats

  • Waliullah, S;Javed, Kalim;Jafri, MA;Singh, S
    • Advances in Traditional Medicine
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    • v.8 no.3
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    • pp.302-310
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    • 2008
  • Azadirachta indica A. Juss (N.O. Meliaceae), popularly known, as 'Neem' is an indigenous tree widely available in India. Almost every part of the tree has long been used in Unani system of medicine for the treatment of a variety of human ailments. The flowers have been mentioned as a remedy useful in controlling diabetes mellitus. The present study had been designed to investigate the hypoglycemic/anti-hyperglycemic effects of the methanolic extract of the flowers of A. indica (Gule-Neem) and its different fractions on normal, glucose fed hyperglycemic, adrenaline induced hyperglycemic and alloxan induced diabetic rats. The methanolic extract was resolved into water soluble and water insoluble fractions. Water soluble portion of the methanolic extract was found to possess significant blood sugar lowering effect in glucose-fed and adrenaline-induced hyperglycemic rats but it did not show such effect in normal and alloxan induced mild and severe diabetic rats. Water-soluble portion was fractionated by employing the polarity criterion with ethyl acetate and butanol. The ethyl acetate fraction was further fractionated into phenolic and non-phenolic fractions. Hypoglycemic effect of these fractions was also evaluated. The results suggest that the flowers of A. indica contain at least two different constituents, responsible for the said activity. These investigations validate the use of flowers of A. indica in diabetes by Unani physicians.

A Paleomagnetic Study of Cretaceous Rocks from the Euiseong Area (의성지역에 분포하는 백악기 지층에 대한 고지자기 연구)

  • Doh, Seong-Jae;Kim, Kwang-Ho
    • Economic and Environmental Geology
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    • v.27 no.3
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    • pp.263-279
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    • 1994
  • Paleomagnetic and rock-magnetic data of Cretaceous sedimentary and volcanic rocks from the Euiseong area indicate that the stable components of remanence are carried by single and pseudo-single domain magnetite, with the exception of the Shinyangdong Formation which has been remagnetized. The Hayang Group, except for the remagnetized Shinyangdong Formation, yields the mean characteristic direction of $D/I=22.5^{\circ}/57.2^{\circ}$ (${\alpha}_{95}=4.6^{\circ}$, N=14 sites) and the pole position is $72.0^{\circ}N$, $206.4^{\circ}E$ ($dp/dm=4.9^{\circ}/6.7^{\circ}$). The Yucheon Group shows two polarities and the mean characteristic direction of $D/I=351.2^{\circ}/60.5^{\circ}$ (${\alpha}_{95}=11.2^{\circ}$, N= 19 sites) and the pole position is $81.3^{\circ}N$, $79.0^{\circ}E$ ($dp/dm=13.0^{\circ}/17.0^{\circ}$). The mean directions of both the Hayang and the Yucheon Groups are supported by the McElhinny's fold test at the 99% confidence level and that of the Yucheon Group by a reversal test at the 95% confidence level. A magnetostratigraphic correlation between polarities of the study formations and the Geomagnetic Time Scale indicates that the Hayang Group can be correlated to the Cretaceous Long Normal Superchron (CLNS), and the Yucheon Group to the boundary between the CLNS and the Polarity Chron 33R or later boundaries between normal and reverse polarities. Comparison of the paleopoles from this study with those from the surrounding areas both within the Gyeongsang basin and in the northeastern Asia indicates that the study area was not undergone significant tectonic rotations with respect to the other parts of the Gyeongsang basin and that the Korean Peninsula was the part of the single terrane of the northeastern Asia at least since the CLNS. The Yucheon Group can be divided into four sub-groups based on the paleomagnetic data, suggesting that there were at least four times of volcanic activities in the study area.

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The embryological studies on the interspecific hybrid of ginseng plant (Panax ginseng x P. Quiuquefolium) with special references to the seed abortion (인삼의 종간잡종 Panax ginseng x P Quinquefoilium의 발생학적 연구 특히 결실불능의 원인에 관하여)

  • Jong-Kyu Hwang
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.5 no.1
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    • pp.69-86
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    • 1969
  • On the growing of the interspecific hybrid ginseng plant, the phenomena of hybrid vigoures are observed in the root, stem, and leaf, but it can not produce seeds favorably since the ovary is abortive in most cases in interspecific hybrid plants. The present investigation was undertaken in an attempt to elucidate the embryological dses of the seed failure in the interspecific hybrid of ginseng (Panax Ginseng ${\times}$ P. Quinque folium). And the results obtained may be summarized as follows. 1). The vegetative growth of the interspecific hybrid ginseng plant is normal or rather vigorous, but the generative growth is extremely obstructed. 2). Even though the generative growth is interrupted the normal development of ovary tissue of flower can be shown until the stage prior to meiosis. 3). The division of the male gameto-genetic cell and the female gameto-genetic cell are exceedingly irregular and some of them are constricted prior to meiosis. 4). At meiosis in the microspore mother cell of the interspecific hybrid, abnormal division is observed in that the univalent chromosome and chromosome bridge occure. And in most cases, metaphasic configuration is principally presented as 23 II+2I, though rarely 22II+4I is also found. 5). Through the process of microspore and pollen formation of F1, the various developmental phases occur even in an anther loclus. 6). Macro, micro and empty pollen grains occur and the functional pollen is very rare. 7). After the megaspore mother cell stage, the rate of ovule development is, on the whole, delayed but the ovary wall enlargement is nearly normal. 8). Degenerating phenomena of ovules occur from the megaspore mother cell stage to 8-nucleate embryo sac stage, and their beginning time of constricting shape is variously different. 9). The megaspore arrangement in the parent is principally of the linear type, though rarely the intermediate type is also observed, whereas various types, viz, linear, intermediate, Tshape, and I shape can be observed in hybrid. 10). After meiosis, three or five megaspore are some times counted. 11). Charazal end megaspore is generally functional in the parents, whereas, in F1, very rarely one of the center megaspores (the second of the third megaspore) grows as an embryo sac mother cell. 12). In accordance with the extent of irregularity or abnormality in meiosis, division of embryo sac nuclei and embryo sac formation cause more nucellus tissue to remain within th, embryo sac. 13). Even if one reached the stage of embryo sac formation, the embryo sac nuclei are always precarious and they can not be disposed to theil proper, respective position. 14). Within the embryo sac, which is lacking the endospermcell, the 4-celled proembryo, linear arrangement, is observed. 15). Through the above respects, the cause of sterile or seed failure of interspecific hybrid would be presumably as follows, By interspecific crossing gene reassortments takes place and the gene system influences the metabolism by the interference of certain enzyme as media. In the F1 plant, the quantity and quality of chemicals produced by the enzyme system and reaction system are entirely different from the case of the parents. Generally, in order to grow, form, and develop naw parts it is necessary to change the materials and energy with reasonable balance, whereas in the F1 plant the metabolic process becomes abnormal or irregular because of the breakdown of the balancing. Thus the changing of the gene-reaction system causes the alteration of the environmental condition of the gameto-genetic cells in the anther and ovule; the produced chemicals cause changes of oxidatio-reduction potential, PH value, protein denaturation and the polarity, etc. Then, the abnormal tissue growing in the ovule and emdryo sac, inhibition of normal development and storage of some chemicals, especially inhibitor, finally lead to sterility or seed failure. Inconclusion, we may presume that the first cause of sterile or seed abortion in interspecific hybrids is the gene reassortment, and the second is the irregularity of the metabolic system, storage of chemicals, especially inhibitor, the growth of abnormal tissue and the change of the polarity etc, and they finally lead to sexual defect, sterility and seed failure.

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Cytologic Features of Endometrial Hyperplasia : Comparison with Normal Endometrium and Endometrial Adenocarcinoma (자궁내막증식증의 세포학적 고찰: 정상자궁내막세포 및 자궁내막선암종과 비교)

  • Hong, Sung-Ran;Seon, Mee-Im;Kim, Yee-Jeong;Chun, Yi-Kyeong;Kim, Hye-Sun;Kim, Hy-Sook
    • The Korean Journal of Cytopathology
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    • v.11 no.1
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    • pp.1-10
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    • 2000
  • The purpose of this study is to describe the cellular characteristics of endometrial hyperplasia without/with atypia in cervical smears. These cellular features were compared with those of normal endometrium and endometrial carcinoma. We reviewed 265 cervical smears : 64 normal proliferative endometrium, 118 endometrial hyperplasia without atypia, 21 endometrial hyperplasia with atypia, and 62 endometrial adenocarcinoma. Of these smears, 72(27.2%) smears which had diagnostic endometrial epithelial cells were selected for this study. The cytologic abnormalities about cellularity, background, changes in cellular architecture, alterations in nuclear size, anisokaryosis, chromatin pattern, nucleoli, cytoplasmic vacuoles, and mitosis were observed. Nuclear enlargement(1.6 to 2 times of the nucleus in the intermediate squamous cell) and anisokaryosis(${\geq}$2 fold in size variation) were highly suggestive of endometrial hyperplasia without/with atypia. The nuclei from endometrial hyperplasia with atypia were more coarsely granular in chromatin patterns than hyperplasia without atypia(33.3% vs 3.4%). Micronucleoli were observed in all endometrial conditions, but the presence of macronucleoli were more suggestive of hyperplasia with atypia(22.2%) and adenocarcinoma(55%). The changes in cellular architecture(loss of polarity, uneven internuclear distance, overlapping and loose arrangement) were seen in hyperplasia with atypia and adenocarcinoma. Characteristically, bloody background was seen in endometrial hyperpiasia, and cellular detritus or granular proteinaceous material was only observed in endometrial adenocarcinoma. Mitoses were also observed in adenocarcinoma. In conclusion, although there is no single parameter useful for the cytologic differential diagnosis of endometrial lesions, combined cytologic evaluation can be used to diagnose hyperplasia cytologically.

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Asexual Propagation of Kalopanax pictus by Root Cutting (근삽에 의한 음나무의 무성번식)

  • Kim, Chul-Woo;Song, Jae-Mo;Bae, Chan-Ho;Park, Bong-Jae;Moon, Heung-Kyu;Hwang, Suk-In;Yi, Jae-Seon
    • Journal of Forest and Environmental Science
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    • v.18 no.1
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    • pp.1-6
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    • 2001
  • This research was carried out to establish the large quantity propagation system for Kalopanax pictus using root cutting. The results are as follows. As there was no significant difference in the promotion of adventitious shoot development from the root cuttings of Kalopanax pictus among kinds (IBA, NAA and Kinetin) and concentrations (0 to 2000 mg/L) of growth regulators, no application is recommended, which showed more than 90% of shoot development. Horizontal and vertical placement of rooting showed more than 93% of shoot occurrence, but the latter showed more desirable growth traits in the number of shoot development, number of leaf, petiole length, and leaf length and leaf width Polarity was observed and thus normal vertical placement of root cutting is preferred. However, root cuttings placed upside down showed the shoot development at the distal end, which indicates further sophisticated test is necessary to investigate this phenomenon.

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Studies of Silyl-Transfer Photochemical Reactions of N-[(Trimethylsilyl)alkyl]saccharins

  • Cho, Dae-Won;Oh, Sun-Wha;Kim, Dong-Uk;Park, Hea-Jung;Xue, Jin-Ying;Yoon, Ung-Chan;Mariano, Patrick S.
    • Bulletin of the Korean Chemical Society
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    • v.31 no.9
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    • pp.2453-2458
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    • 2010
  • Photochemical studies of N-[(trimethylsilyl)alkyl]saccharins were carried out to investigate their photochemical behavior. Depending on the nature of the substrate and the solvent system employed, reactions of these substances can take place by either SET-promoted silyl migration from carbon to either the amide carbonyl or sulfonyl oxygen or by a N-S homolysis route. The results of the current studies show that an azomethine ylide, arising from a SET-promoted silyl migration pathway, is generated in photoreactions of N-[(trimethylsilyl)methyl]saccharin and this intermediate reacts to give various photoproducts depending on the conditions employed. In addition, irradiation of N-[(trimethylsily)ethyl]saccharin produces an excited state that reacts through two pathways, the relative importance is governed by solvent polarity and protic nature. Finally, photoirradiation of N-[(trimethylsilyl)propyl]saccharin in a highly polar solvent system comprised of 35% aqueous MeOH gives rise to formation of a tricyclic pyrrolizidine and saccharin that generated via competitive SET-promoted silyl transfer and $\gamma$-hydrogen abstraction pathways.

Feature Weighting for Opinion Classification of Comments on News Articles (뉴스 댓글의 감정 분류를 위한 자질 가중치 설정)

  • Lee, Kong-Joo;Kim, Jae-Hoon;Seo, Hyung-Won;Rhyu, Keel-Soo
    • Journal of Advanced Marine Engineering and Technology
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    • v.34 no.6
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    • pp.871-879
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    • 2010
  • In this paper, we present a system that classifies comments on a news article into a user opinion called a polarity (positive or negative). The system is a kind of document classification system for comments and is based on machine learning techniques like support vector machine. Unlike normal documents, comments have their body that can influence classifying their opinions as polarities. In this paper, we propose a feature weighting scheme using such characteristics of comments and several resources for opinion classification. Through our experiments, the weighting scheme have turned out to be useful for opinion classification in comments on Korean news articles. Also Korean character n-grams (bigram or trigram) have been revealed to be helpful for opinion classification in comments including lots of Internet words or typos. In the future, we will apply this scheme to opinion analysis of comments of product reviews as well as news articles.

Resistivity Tomography in an Inclined Borehole to Surface Purvey Using a Pole-dipole Array (단극-쌍극자 배열을 이용한 경사시추공-지표 탐사에서 전기비저항 토모그래피)

  • Park Jong-Oh;Kim Hee-Joon;Park Chung-Hwa
    • The Journal of Engineering Geology
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    • v.16 no.3 s.49
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    • pp.255-263
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    • 2006
  • In an electrical tomographic survey using an inclined borehole with a pole-dipole array, we must consider several factors: a singular point associated with zero potential difference, a spatial discrepancy between electrode and nodal point in a model due to a inclined borehole, and a variation of geometric factors in connection with a irregular topography. Singular points which are represented by the normal distance from current source to the ground surface can be represented by serveral regions due to a irregular topography of ground surface. The method of element division can be applied to the region in which the borehole is curved, inclined or the distance between the electrodes is shorter than that of nodal points, because the coordinate of each electrode cannot be assigned directly to the nodal point if several electrodes are in an element. Test on a three-dimensional (3-D) synthetic model produces good images of conductive target and shoves stable convergence.

Paleomagnetic Study of the Yeonil Group in Pohang Basin (포항분지(浦港盆地)에 분포(分布)하는 연일층군(延日層群)의 고지자기(古地磁氣) 연구(硏究))

  • Kim, Kwang Ho;Doh, Seong-Jae;Hwang, Chang-Soo;Lim, Dong Seong
    • Economic and Environmental Geology
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    • v.26 no.4
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    • pp.507-518
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    • 1993
  • Paleomagnetic investigations have been carried out on the Tertiary sedimentary formations (Yeonil Group) in Pohang basin, southeastern Korea. A total of 215 samples were collected from 26 sites. Progressive thermal demagnetization indicates that many samples have unstable magnetization and do not reveal a characteristic direction. However, some samples from the lower and upper Duho Formation show a characteristic direction $D/I=7.8^{\circ}/48.3^{\circ}$ (${\alpha}_{95}=3.7^{\circ}$, k=174.1). Stepwise thermal demagnetization data show that some samples from the Hagjeon and middle Duho Formations reveal great-circle distributions moving from the present to a reversed direction of geomagnetic field. The mean of intersection points of the great-circles is nearly antipodal to the characteristic normal direction of the lower and upper Duho Formation. We infer that the Hagjeon Formation was formed during the reversed polarity chron C5B (16.2~14.7 Ma) and the Duho Formation 14.7~11.6 Ma based on our results and previous paleontologic and age dating data. Paleomagnetic direction for the Middle Miocene of Korea, analysed from the combined results of stable endpoints and great circles, is $D/I=8.7^{\circ}/53.9^{\circ}$ (${\alpha}_{95}=4.2^{\circ}$, k=74.8), and the corresponding paleopole is Lat./Long.=$82.7^{\circ}/230.2^{\circ}$ (${\delta}p=2.8^{\circ}$, ${\delta}m=5.9^{\circ}$). On the basis of this, we interpret that the opening of the East sea (Japan sea) or the synchronous clockwise rotation of the Southwest Japan exerted no structural influence on the Yeonil Group in the Middle Miocene.

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Visualization of Geometric Features in the Contact Region of Proteins (단백질 접촉 영역의 기하학적 특성 가시화)

  • Kim, Ku-Jin
    • KIPS Transactions on Software and Data Engineering
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    • v.8 no.10
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    • pp.421-426
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    • 2019
  • In this paper, we propose a method to visualize the geometric features of the contact region between proteins in a protein complex. When proteins or ligands are represented as curved surfaces with irregularities, the property that the two surfaces contact each other without intersections is called shape compatibility. Protein-Protein or Protein-Ligand docking researches have shown that shape complementarity, chemical properties, and entropy play an important role in finding contact regions. Usually, after finding a region with high shape complementarity, we can predict the contact region by using residual polarity and hydrophobicity of amino acids belonging to this region. In the research for predicting the contact region, it is necessary to investigate the geometrical features of the contact region in known protein complexes. For this purpose, it is essential to visualize the geometric features of the molecular surface. In this paper, we propose a method to find the contact region, and visualize the geometric features of it as normal vectors and mean curvatures of the protein complex.