• Korean Journal of Veterinary Research
• /
• v.19 no.2
• /
• pp.99-105
• /
• 1979

In order to know the histological changes of rat preputial gland during normal sexual cycle and sex hormone treatment, matured Wistar rats (B.W.about 200g) were used for the experiment. Rats were subcutaneously given $2{\mu}g$ 17-${\beta}$-estradiol (Sigma) and 2.5g progesterone (Nakarai Chem., Japan) daily in 0.5ml propylen glycol for ten days respectively. The results obtained are as follow: At the stage of estrus and metestrus, the eosinophilic crystalloid granules and large vacuoles in the acinar cells appeared numerously, and the excretory ducts were severely extended. The developed connective tissue between the acinus were also found. At the stage of proestrus and diestrus, however, the small vacuoles and a few eosinophilic crystalloid granules appeared in the acinar cell. In the estradiol treatment, on the other hand, severely extended excretory ducts and a small number of the eosinophilic crystalloid granules compared with the progesterone treatment were found. The cyst-like structure was found, and in that the acinus disappeared completely. In the progesterone treatment, remarkably extended excretory ducts and nomerous appearance of oval formed eosinophilic granules in the acinar cells were found. As these findings, it could be suggested that the secretion of rat preputial gland was active at the estrus and metestrus stage, and estrogen may concerned in the secretion, land progesterone in the formation of secretory products.

• The Journal of Korean Physical Therapy
• /
• v.14 no.3
• /
• pp.373-406
• /
• 2002

This study was peformed to investigate the effects on skeletal muscle recovery with aqua-exercise; swimming to take the muscle endurance for 20 days on two group of white rats which were the low extremity atrophy group(control groups) by fixed for two weeks and aqua-exercise group(experimental groups) after it. The effects was observed with light and electron microcope to measure the morphological changes of muscle fibers. The results obtained were as follow. 1. Light microscope: In the case of control groups, quadriceps fibers had been irregular alignment, decreased muscle width and the irregular alignment nuclear appeared, as it is degenerative muscle fibers. In the case of experimental groups, the fibers had been regular alignment cells and fibers. The nucleus of muscle had been normal characterized by oval shape and fiber sarcomere clearly classified. 2. Electron microscope: In the case of control groups, there were the quadriceps which was Z-line streaming phenomenon induced at the sarcomere and cells nuclear separated from basal membrane. It was not only observed the sarcomere alignment irregularly and mitochondria damaged, but also vacuoles found. In the case of experimental groups, A band, I band, H band had been clearly appeared, classified at the myofibrils of quadriceps, and electronic dense M-line found in sarcomere. There were observed satellite cells and basal laminas that usually to be appeared at the time of mitochondrial development, skeletal muscle fiber regeneration or development. This results suggest that the aqua-exercise assisted to inhibit the degenerative morphological changes of skeletal muscle cells and help to recover from abnormal states. Especially, it is considered to effect on a normal structural formation.

• Clinical and Experimental Reproductive Medicine
• /
• v.27 no.3
• /
• pp.301-305
• /
• 2000

Globozoospermia is a rare type of teratozoospermia. It occurs in 0.1% of all andrological patient's and used to be considered sterile. Globozoospermic patient has 100% round headed spermatozoa, but the spermiogram is normal. The spermatozoa show oval-shape head, the lack of a nuclear envelope, acrosome, and post acrosomal sheath. Objective: To report that a couple with infertility secondary to globozoospermia received ICSI treatment. Material and Method: Case report Results: In the first trial, fertilization was failed. In the second trial, 40% of oocytes were fertilized and all of these embryos were cleaved, but pregnancy did not achieved. In the third trial, sperm injected oocytes were exposed to 10 ${\mu}M$ calcium ionophore for 15 min. All of the injected oocytes were fertilized and proceeded to develop. Triplet pregnancy was achieved after the transfer of six embryos in their third cycle. One embryo vanished and the remaining twins (female) were delivered at 33 weeks of gestation by Caesarean section. Conclusion: This result shows that assisted activation following ICSI may overcome infertility associated with globozoospermia.

• Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
• /
• v.23 no.1
• /
• pp.52-55
• /
• 2012

Background and Objectives : Based on histological findings, intracordal cysts are divided in two subtypes : retention cysts and epidermoid cysts. They are typically located in the superficial layer of the lamina propria and appeared as opaque ovoid buldging masses underlying the epithelium. They are characterized by unilateral diminished mucosal wave on stroboscopy. In this article, we report some cases of patients with an oval shaped-yellowish flat cyst. Materials and Method : At the clinic of the department of otorhinolaryngology in Gangnam Severance Hospital, with 3 female complained of hoarseness as subjects, using the stroboscopy we checked preoperative and postoperative vocal cord and operative findings. Surgery was performed under general anesthesia by the senior authors. All patients noted subjectively that their performing voice was improved. Results : During surgery, an oval shaped-yellowish flat cystic lesion was distinguished from normal epithelium. On palpation of this area with microforceps and cottons, the yellowish discharge was noted to move out from the opening of the cyst. In one case, the cyst was ruptured but remove the capsule completely. In other cases, sulcus was noted at the oppsite site. Conclusion : Because of the opening, the cyst was not easy to dissect and remove completely. After the debris was move out, fibrosis around the opening and invaginated epithelium extending into the deeper layers to the fold. The cyst was must removed carefully and completely for improvement of voice quality before evolving into a sulcus vocalis.

• Clinical and Experimental Reproductive Medicine
• /
• v.42 no.4
• /
• pp.156-162
• /
• 2015

Objective: To investigate fertilization and embryo quality of dysmorphic mature oocytes with specific morphological abnormalities obtained from intracytoplasmic sperm injection (ICSI). Methods: The fertilization rate (FR) and embryo quality were compared among 58 dysmorphic and 42 normal form oocytes (control 1) obtained from 35 consecutive ICSI cycles, each of which yielded at least one dysmorphic mature oocyte, performed over a period of 5 years. The FR and embryo quality of 441 normal form oocytes from another 119 ICSI cycles that did not involve dysmorphic oocytes served as control 2. Dysmorphic oocytes were classified as having a dark cytoplasm, cytoplasmic granularity, cytoplasmic vacuoles, refractile bodies in the cytoplasm, smooth endoplasmic reticulum in the cytoplasm, an oval shape, an abnormal zona pellucida, a large perivitelline space, debris in the perivitelline space, or an abnormal polar body (PB). Results: The overall FR was significantly lower in dysmorphic oocytes than in normal form oocytes in both the control 1 and control 2 groups. However, embryo quality in the dysmorphic oocyte group and the normal form oocyte groups at day 3 was similar. The FR and embryo quality were similar in the oocyte groups with a single abnormality and multiple abnormalities. Specific abnormalities related with a higher percentage of top-quality embryos were dark cytoplasm (66.7%), abnormal PB (50%), and cytoplasmic vacuoles (25%). Conclusion: The fertilization potential of dysmorphic oocytes in our study was lower, but their subsequent embryonic development and embryo quality was relatively good. We were able to define several specific abnormalities related with good or poor embryo quality.

• Korean Journal of Veterinary Research
• /
• v.15 no.2
• /
• pp.241-250
• /
• 1975

The light and electron microscopic observations were carried out in order to know the morphological changes of the testicular Leydig cells in the mouse injected with testosterone propionate for a long period. The results obtained were as follows: With the light microscopic study, atrophy of the Leydig cells and larger sudanophilic lipid granules in the experimental group than normal were observed. 2. By the electron microscopic finding, the small spherical or oval mitochondria, large lipid droplets, a decrease in number of smooth endoplasmic reticutum and distended saccular or vacuolar smooth endoplasmic reticulum were observed in the experimental group. Membranous whorls with droplet increased in number and size in the experimental group.

• The Korean Journal of Cytopathology
• /
• v.5 no.2
• /
• pp.180-183
• /
• 1994

A case of metastatic mucoepidermoid carcinoma of the lung, originating from the hard palate, was diagnosed by sputum and bronchial washing cytology. Although the cytologic features of mucoepidermoid carcinoma have been well described, it is easy to confuse mucoepidermoid carcinoma with the more common primary adenocarcinoma or squamous cell carcinoma of the lung. The features distinguishing mucoepidermoid carcinoma from other primary neoplasms include 1) mucus-secreting cells individually and in clusters admixed with other cell components, 2) epidermoid cells identified by the presence of abundant spread-out cytoplasm and an oval dark nucleus and 3) intermediate cells resembling normal ductal epithelial cells with moderate-to-scanty cytoplasm, a central, round vesicular nucleus and a prominent nucleolus. The morphologic features of metastatic mucoepidermoid carcinoma in this case were similar to those of primary salivary mucoepidermoid carcinoma.

• Korean Journal of Veterinary Service
• /
• v.40 no.2
• /
• pp.139-142
• /
• 2017

A six-year-old male captive nutria (Myocastor coypus) maintained in a closed space with a small vent was found dead in his cage. Gross findings showed multifocal nodules in varying sizes, small 0.5 to large 5 cm in diameter, intermixed with normal parenchyma were scattered all over the surface of the lungs and a kidney, which the cut surface was smooth, compact and whitish in color. Microscopically, small round to oval neoplastic cells with modest to slight amounts of cytoplasm formed acinar and gland-like structures. Immunohistochemically, cells were strongly positive for E-cadherin and slightly reactive for thyroid transcription factor-1 (TTF-1). Based on those diagnostic features, the neoplasia was diagnosed as primary pulmonary adenocarcinoma (small cell type) and metastasized into the kidney. This is the first case report of malignant pulmonary tumor and its metastasis in the nutria.

• Journal of Korean Ophthalmic Optics Society
• /
• v.12 no.3
• /
• pp.35-38
• /
• 2007

This study surveyed on eye size, face types and glasses wears of normal 100 young peoples from 20 to 30 years old. The analysis of data resulted in as follows: 1. The vertical eye size were in case of below 2.4 mm (2%), 2.5-2.9 mm (40%), 3.0-3.5 mm (57%), and in case of high 3.6 mm (1%). 2. The horzontal eye size were in case of below 1.1 mm (52%), 1.2-1.4 mm (28%), 1.5-1.7 mm (18%), and in case of high 1.8 mm (2%). 3. As a whole, the face types were oval type (29%), round type (24%), square type (18%), and triangle type (2%). 4. As the male, the face types were oval type (32%), round type (10%), square type (26%), and triangle type (32%). 5. As the female, the face types were oval type (18%), round type (40%), square type (12%), and triangle type (30%). 6. As a whole, the FPD size were in case of larger than PD (49%), in case of suitable (25%), in case of smaller than PD (49%). 7. As the male, the FPD size were in case of larger than PD (28%), in case of suitable (36%), and in case of smaller than PD (32%). 8. As the female, the FPD size were in case of larger than PD (44%), in case of suitable (26%), and in case of smaller than PD (30%).

• Korean Journal of Head & Neck Oncology
• /
• v.23 no.1
• /
• pp.41-45
• /
• 2007

A 60 years old female patient presented with $8{\times}6\;cm$ sized painless oval mass in the left parietal region. She had left lobectomy of thyroid gland 10 years ago. Cranial CT, MRI, FGD PET-CT showed a solid mass which invaded left parietal bone. After embolization, craniectomy with tumor excision was performed. Histological examination revealed metastatic follicular cancer originated thyroid gland, with vascular and dura invasion. Postoperatively, neck CT showed right thyroid multiple nodules and right level III multiple lymph node enlargement. Thyroid function test was normal, but level of thyroglobulin was high (72ng/ml). So she had right lobectomy of thyroid gland with lymph node dissection under a diagnosis of follicular carcinoma. But histological examination revealed adenomatous hyperplasia and not lymph node metastasis. After operation, she received radioiodine therapy of 150mCi and then the level of thyroglobulin normalized (8.4ng/ml). The patient is under follow-up since she had operation 4 months ago.