• Journal of Nutrition and Health
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• 제34권3호
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• pp.299-305
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• 2001

The purpose of this study was to investigate the effects of catechin on the changes of microsomal mixed function oxidase(MFO) system and oxidative damage in rat liver exposed to microwave. Sprague-Dawley male rats weighing 200$\pm$10g body weight were randomly assigned to one normal and microwave exposed groups: microwave exposed groups were divided three groups: catechin free diet(MW) group, 0.25% catechin(MW+0.25C) group and 0.5% catechin(MW+0.5C) group to the levels of dietary catechin supplementation. The rats were irradiated with microwave at frequency 2.45GHz for 15 min and then the changes pattern of mixed function oxidase system and oxidative damage were investigated for 16 days. The activity of XOD in MW group was increased from 4 day to 8 days after irradiation, compared to normal group and decreased to the level of normal group 16 days. But catechin supplementation group were maintained to the normal level. The contents of cytochrome P(sub)450 and NADPH cytochrome P(sub)450 reductase activities in liver of MW group was increased from 4 day to 8 day after irradiation, compared to normal group and decreased to the level of normal group at 16 day. But catechin supplementation group were recovered to the normal level. The contents of superoxide radical in liver of MW group was increased 1.28, 1.25, 1.17 fold of normal group at 4,6 and 8 days days after irradiation. respectively, but catechin supplementation group were maintained the normal level. The contents of lipifuscin in liver have a same tendency in superoxide radical contents. These result suggested that the supplementation of catechin have control the mixed function oxidase system and oxidative damage and that may help to recover tissues from microwave damage. (Korean J Nutrition 34(3) : 299~305, 2001)

• 성인간호학회지
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• 제13권3호
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• pp.451-462
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• 2001

This study was conducted to examine and compare the characteristics in the cognitive functions of peritoneal dialysis, hemodialysis and normal kidney function groups as basic data for effectively educating dialysis patients. The data were collected from May 10 to October 30. 2000, collected from each of 20 patients with peritoneal dialysis, hemodialysis and normal Kidney function and who registered for the dialysis room at a general hospital affiliated to a university in Seoul and sampled by age and educational level through personal interviews with the researchers of this study. As a measuring tool, MMSE developed by Folstein et al.(1975) to measure cognitive function disorder was used, slightly revised for hemodialysis patients. Collected data were processed into frequency, percentage, mean, and standard deviation by the use of SAS. The results of this study are as follows : 1. With a maximum of 30 points for cognitive function, the mean of the peritoneal dialysis patients was $27.06{\pm}2.06$, while that of the hemodialysis patients was $27.25{\pm}2.76$; that of the normal Kidney function patients was $27.85{\pm}2.00$, indicating no significant difference among those three groups. 2. As for the subjects who scored 23 points, the turning point of confirming the cognitive disorder, the percentage was 5% in the case of the peritoneal dialysis, 10% in the case of the hemodialysis and 5% in the case of the normal Kidney function group. 3. Differences between the peritoneal dialysis and hemodialysis patients by gender, occupation, spouse, diabetes, hypertension, the period of dialysis, number of hospitalizations, and the use of erythropoietin were not significant in the scoring of cognitive function. 4. There was no significant correlation between the level of Hb, Hct, albumin, aluminium, PTH, BUN, Cr, dialysis adequacy and the cognitive function. Considering such results, it is clear that there is no significant difference in the cognitive functions of the sampled subjects. Therefore, the nurse in the dialysis room should continually carry out assessment and intervention against elements degrading the effect of patients' education to improve self- care.

• 아동학회지
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• 제23권6호
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• pp.65-79
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• 2002

The present study surveyed both the parents of 130 children with psychopathology and the parents of 240 normal children. children were between 2 and 12 years of age. No differences were found between parents in self-differentiation or in family function by type of disorder. Parents of children with psychopathology were lower than parents of normal children in self-differentiation; this was particularly evident in cognitive function-emotional function, and emotional cut-off. Patents of children with psychopathology were lower than parents of normal children in terms of family function. Multiple regression analyses indicated that parent's self-differentiation, children's psychopathology, and parent's education level had a significant influence on family function. The regression model explained 52% of the variance.

• 한국전문물리치료학회지
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• 제25권1호
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• pp.12-21
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• 2018

Background: Research efforts to improve the pulmonary function of children with cerebral palsy (CP) need to focus on their decreased diaphragmatic ability compared to normal children. Real-time ultrasonography is appropriate for demonstrating diaphragmatic mechanisms. Objects: This study aimed to compare diaphragm movement, pulmonary function, and pulmonary strength between normal children and children with CP by using ultrasonography M-mode. The correlation between general characteristics, diaphragm movement, pulmonary function, and pulmonary strength was also studied. Methods: The subjects of this study were 25 normal and 25 CP children between five and 14 years of age. Diaphragm movement was measured using real-time ultrasonography during quiet and deep breathing. Pulmonary function (such as forced expiratory volume in one second; FEV1 and peak expiratory flow; PEF) and pulmonary strength (such as maximum inspiratory pressure; MIP and maximum expiratory pressure; MEP) were measured. A paired t-test and Spearman's Rho test, with a significance level of .05, were used for statistical analysis. Results: The between-group comparison revealed that normal children had significantly greater diaphragm movement, FEV1, PEF, MIP, and MEP (p<.05) than CP children. The results showed that general characteristics were significantly related to FEV1, PEF, MIP, and MEP (p<.05). Conclusion: In clinical settings, clinicians need to concern decreased diaphragm movement, pulmonary function, and pulmonary strength in CP group compared to normal children.

• 산업경영시스템학회지
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• 제41권2호
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• pp.174-183
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• 2018

In the industrial fields, the process capability index has been using to evaluate the variation of quality in the process. The traditional process capability indices such as $C_p$, $C_{pk}$, $C_{pm}$ and $C^+_{pm}$ have been applied in the industrial fields. These traditional process capability indices are mainly applied in the univariate analysis. However, the main streams in the recent industry are the multivariate manufacturing process and the multiple quality characteristics are corrected each other. Therefore, the multivariate statistical method should be used in the process capability analysis. The multivariate process indices need to be enhanced with more useful information and extensive application in the recent industrial fields. Hence, the purpose of the study is to develop a more effective multivariate process index ($MC_{pI}$) using the multivariate inverted normal loss function. The multivariate inverted normal loss function has the flexibility for the any type of the symmetrical and asymmetrical loss functions as well as the economic information. Especially, the proposed modeling method for the multivariate inverted normal loss function (MINLF) and the expected loss from MINLF in this paper can be applied to the any type of the symmetrical and asymmetrical loss functions. And this modeling method can be easily expanded from a bivariate case to a multivariate case.

• Structural Engineering and Mechanics
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• 제62권3호
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• pp.365-372
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• 2017

Reliability analysis is a probabilistic approach to determine a safety level of a system. Reliability is defined as a probability of a system (or a structure, in structural engineering) to functionally perform under given conditions. In the 1960s, Basler defined the reliability index as a measure to elucidate the safety level of the system, which until today is a commonly used parameter. However, the reliability index has been formulated based on the pivotal assumption which assumed that the considered limit state function is normally distributed. Nevertheless, it is not guaranteed that the limit state function of systems follow as normal distributions; therefore, there is a need to define a new reliability index for no-normal distributions. The main contribution of this paper is to define a sophisticated reliability index for limit state functions which their distributions are non-normal. To do so, the new definition of reliability index is introduced for non-normal limit state functions according to the probability functions which are calculated based on the convolution theory. Eventually, as the state of the art, this paper introduces a simplified method to calculate the reliability index for non-normal distributions. The simplified method is developed to generate non-normal limit state in terms of normal distributions using series of Gaussian functions.

• 음성과학
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• 제15권2호
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• pp.177-189
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• 2008

This study was to investigate diadochokinetic (DDK) rate, regularity and mean flow rate of articulation valves in dysarthria. DDK rate, mean airflow rate (MFR) and regularity of DDK syllable repetitions of vocal function /ihi/, tongue function /ta/, velopharyngeal function /bm/, and labial function /pa/ in 24 normal and dysarthric speakers were measured. Aerophone Ⅱ and Motor Speech Profile were used for data recording and analysis. The results of the findings were as follows: First, there were significant differences between the dysarthria and the normal group in DDK rate. DDK rates in ataxic dysarthria were the lowest and spastic, flaccid, and hypokinetic dysarthria followed in sequence. Second, there was a significant difference between the dysarthria and the normal group in DDK regularity. Third, there was a significant difference between dysarthria groups and normal group in DDK MFR. Finally, there was a significant difference between the 4 groups of dysarthria and the normal group in DDK air flow tracking. The results of this study can be guidelines for normal DDK rate, regularity and flow rate in dysarthria groups. In addition, their differential diagnoses and descriptions are important to make a decision on medical and behavioral management of the individuals with disorders according to DDK characteristics.

• The Journal of Korean Physical Therapy
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• 제12권3호
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• pp.379-386
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• 2000

This study is aimed to determine the cardiovascular function response to maximal exercise of chronic low back pain patients(N=13) and normal group(N=13). by using BRUCE PROTOCOL, subjects underwent tredmill exercise test. Their cardiovascular function responses during rest and after maximal exercise were compared The responses were analyzed using t-test for SPSS 7.0 program. The Cardiovascular function variables employed at rest time(Vo2, HR. Vo2/kg, VE, Vco2.) and all out time(Vo2peak. HRpeak, Vo2peak/kg, VEpeak. Vco2peak). Result show that : 1 There was no significant difference in Vo2 between chronic low back pain patients and normal group at rest time. However significant difference in Volpeak was observed after maximal exercise( p<.05). 2. There was no significant difference in HR between chronic low back pain patients and normal group at rest time. No significant difference in HRpeak likewise observed. 3. There was no significant difference in Vo2/kg between chronic low back pain patients and normal group at rest time. However significant difference in Vo2peak/kg was observed after maximal exercise load(p<.05). 4. There was no significance in VE between chronic low bark pain patients and normal group at rest time. However significant difference in VEpeak observed after maximal exercise load(p<.05).

• 국제물리치료학회지
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• 제4권1호
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• pp.488-493
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• 2013

The purpose of this study was to investigate spirometric lung pattern, respiratory function and degree of fatigue by lung function tests and fatigue tests of 39 elderly people in a care facility aged 65 and over. The respiratory function tests were used to the Spirovit SP-1 and fatigue tests were used modified Piper fatigue scale(mPFS). Regarding the respiratory function, the FVC was $1.41{\pm}0.36$l, the FVC % predicted was $69.10{\pm}14.98$%, the $FEV_1$ was $1.02{\pm}0.31$l, the $FEV_1$ % predicted was $63.27{\pm}16.05$%, the $FEV_1$/FVC was $72.77{\pm}13.40$%, and the fatigue score was $5.83{\pm}1.09$. As for the spirometric lung pattern, 19 patients had a restrictive pattern(48.7%), followed by 11 with a mixed pattern(28.2%), 5 with an obstructive pattern( 12.8%), and 4 with a normal pattern(10.3%). Regarding the respiratory function and fatigue by spirometric lung pattern, the FVC and the FVC % predicted of patients with a normal pattern or an obstructive pattern were greater than other groups at a statistically significant level. As for the $FEV_1$, that of patients with a normal pattern was significantly higher than others, and for the $FEV_1$ % predicted, that of patients with a normal pattern or a restrictive pattern was significantly higher(p<.001). Fatigue score by patients with a normal pattern was significantly less than patients of other patterns(p<.001). Therefore, pulmonary physical therapy is considered necessary to improve respiratory function and fatigue degradation of elderly in a facility.

• Nutritional Sciences
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• 제7권1호
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• pp.3-7
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• 2004

This study was performed to investigate the effect of a raw diet (RD) on blood glucose and immune function in non-diabetic (normal) and streptozotocin (STZ)-induced diabetic rats. Male Sprague-Dawley rats were assigned to four groups (normal control, normal RD, diabetic control and diabetic RD). The control groups and the RD groups were fed an AIN-diet and RD for four weeks, respectively. Weight gain was statistically lower in the RD groups than in the controls. Fasting plasma glucose was significantly lower in the diabetic RD group than in the diabetic control group. The $CD4^+$ T-cell population was higher along with the $CD4^+/CD8^+$ ratio of the mesenteric lymph nodes in the normal RD group compared to the other groups. It can be concluded that RD may reduce the plasma fasting glucose concentration in diabetic rats and improve mesenteric lymph node immune function in normal rats.