• Journal of Korean Biological Nursing Science
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• 제21권1호
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• pp.85-97
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• 2019

Purpose: This study was performed to analyze the levels of blood pressure and to identify good or poor blood pressure control (BPC) groups among hypertension patients. The study was based on the Korea National Health and Nutrition Examination Survey (KNHANES VI and VII) conducted from 2013 to 2016. Methods: The sociodemographic and clinical data of 4,151 Korean hypertension patients aged 20-79 years and who were taking antihypertensive medications was extracted from the KNHANES VI and VII database. Descriptive statistics for complex samples and a decision-tree analysis were performed using the SPSS WIN 24.0 program. Results: The mean age was $62.46{\pm}0.21years$. The mean systolic blood pressure (SBP) was $128.07{\pm}0.28mmHg$, and the diastolic blood pressure (DBP) was $76.99{\pm}0.21mmHg$. 71.9% of participants showed normal blood pressure (SBP < 140mmHg and DBP < 90mmHg). From the decisiontrees analysis, the characteristics of participants related to good BPC group were presented with 9 different pathways same as those from the poor BPC group. Good or poor BPC groups were classified according to the patients' characteristics such as age, living status, occupation, education, hypertension diagnosis period, numbers of comorbidity, perceived health status, total cholesterol, high density lipoprotein-cholesterol, alcohol drinking per month, and depressive mood. Total cholesterol level (< 201mg/dL or ${\geq}201mg/dL$ cutoff point) was the most significant predictor of the participants' BPC group. Conclusion: This decision-tree model with the 18 different pathways can form a basis for the screening of hypertension patients with good or poor BPC in either clinical or community settings.

• BMB Reports
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• 제52권3호
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• pp.202-207
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• 2019

Keloids are the most common pathological form of trauma healing, with features that seriously affect appearance and body function, are difficult to treat and have a high recurrence rate. Emerging evidence suggests that miRNAs are involved in a variety of pathological processes and play an important role in the process of fibrosis. In this study, we investigated the function and regulatory network of miR-152-5p in keloids. The miRNA miR-152-5p is frequently downregulated in keloid tissue and primary cells compared to normal skin tissue and fibroblasts. In addition, the downregulation of miR-152-5p is significantly associated with the proliferation, migration and apoptosis of keloid cells. Overexpression of miR-152-5p significantly inhibits the progression of fibrosis in keloids. Smad3 is a direct target of miR-152-5p, and knockdown of Smad3 also inhibits fibrosis progression, consistent with the overexpression of miR-152-5p. The interaction between miR-152-5p and Smad3 occurs through the Erk1/2 and Akt pathways and regulates collagen3 production. In summary, our study demonstrates that miR-152-5p/Smad3 regulatory pathways involved in fibrotic progression may be a potential therapeutic target of keloids.

• 한국물환경학회지
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• 제35권2호
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• pp.165-180
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• 2019

Water quality data of 81 lakes in Korea, 2013 ~ 2017 were analyzed. Most water quality parameters showed left-skewed distribution, while dissolved oxygen showed normal distribution. pH and dissolved oxygen showed a positive correlation with organic matter and nutrients, which appeared to be a nonsense correlation mediated by the algae. The ratio of $BOD_5$ and $COD_{Mn}$ to CBOD was 21 % and 52 % in the freshwater lakes, respectively. TOC concentration appeared to be underestimated by the UV digestion method, when salinity exceeds $700{\mu}S\;cm^{-1}$. In terms of nitrogen/phosphorus ratio, the limiting factor for algal growth seemed to be phosphorus in most of the lakes. Chlorophyll ${\alpha}$ increased acutely with decrease of N/P ratio. However, it seemed to be a nonsense correlation mediated by phosphorus concentration, since the N/P ratio depended on phosphorus. The N/P ratio of brackish lakes was lower than that of the freshwater, at the same concentration of phosphorus. It is worth examining denitrification that occurs, in bottom layer and sediment, during saline stratification. $Chl.{\alpha}$ concentration decreased in the form of a power function with increase of mean depth. The primary reason is that deep lakes are mainly at the less-disturbed upstream. However, it is necessary to investigate the effect of sediment, on water quality in shallow lakes. Light attenuation in the upper layer, was dominated by tripton (non-algal suspended solids) absorption/scattering (average relative contribution of 39 %), followed by CDOM (colored dissolved organic matter) (average 37 %) and $Chl.{\alpha}$ (average 21 %).

• 한국컴퓨터정보학회논문지
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• 제26권4호
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• pp.169-179
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• 2021

본 연구의 목적은 당뇨병 문제를 관리하는데 있어서 개인이 어떻게 행동과정에 대해 결정을 내리는지를 설명하는 자기조절의 인식유형과 특성을 탐색하고, 이를 근거로 당뇨병 환자의 관리방법을 제시하고자 시도되었다. 총 40개의 Q-표본과 38명의 P-표본이 본 연구에 사용되었으며 응답자의 반응은 Q방법론에 기초한 요인분석을 통해 5개의 유형이 도출되었다. 각 유형의 특성은 근거기반 순응형(evidence-based compliance), 위기대응 거부반응(crisis responding denial reaction), 정보기반 관계지향형(information-based orientation to relationship), 독립적 실천형(independent practice), 의지결핍 충동반응형(willingness deficit impulse reaction)으로 명명되었다. 5개 유형으로 분류된 응답자의 특성을 자기조절 속성에 따라 포지셔닝 시킴으로써 당뇨병 관리의 전략적 함의를 도출하였다.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제47권3호
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• pp.183-189
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• 2021

Objectives: To assess the prevalence and recovery of inferior alveolar nerve dysfunction (IAND) in mandibular fractures. Materials and Methods: This was a prospective cohort study. Clinical neurosensory testing was done preoperatively and the IAND was categorized as mild, moderate or severe. Postoperatively, neurosensory testing was repeated at 1 day, 1 week, 1 month, 3 months and every 3 months thereafter. Results: A total of 257 patients with 420 fractures were included in the study with a mean age of 31.7 years. Body fractures (95.9%) had the highest incidence of IAND, followed by the angle fractures (90.1%) and symphysis fractures (27.6%). The condyle and coronoid fractures did not have any IAND and hence were excluded from further study. After eliminating those cases, 232 patients remained in the study with 293 fractures. The overall prevalence of IAND in fractures occurring distal to the mandibular foramen was 56.3%. The changes until 1 week were minimal. From 1 month to 6 months, there was a significant reduction in the severity of IAND. A significant number of cases (60.0%) were lost to follow-up between 6 and 9 months. At 6 months, 23.9% of cases still had some form of IAND and 95.0% of the symphysis, 59.0% of the angle and 34.8% of the body fractures with IAND had become normal. Conclusion: This study documents the reduction in the degree of severity of IAND in the first six months and provides the basis for future studies with longer periods of follow-up.

• 정보보호학회논문지
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• 제13권1호
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• pp.139-146
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• 2003

본 논문은 과포화 다변수 방정식을 이용하여 LILI-128 스트림 암호를 분석한다. LILI-128 암호$^{[8]}$ 는 128비트 키를 가진 선형귀환 쉬프트 레지스터 기반의 스트림 암호로 구조를 살펴보면 크게 “CLOCK CONTROL” 부분과 “DATA GENERATION” 부분으로 나뉘어진다. 분석 방법은 “DATA CENERATION” 부분에 사용되는 함수 \ulcorne $r^{d}$ 의 대수적 차수가 높지 못하다는 성질을 이용한다. 간략히 설명하면 차수(K)가 6차인 다변수 방정식을 많이 얻을 수 있고, 이를 7차 (D)의 다변수 방정식으로 확장하여 주어진 변수보다 많은 연립방정식을 얻어 그 해를 구하는 XL 알고리즘을 통해 전수조사보다 빠르게 키정보를 찾을 수 있다. 결과 중 가장 좋은 것은 출력 키수열 2$^{26.3}$비트를 가지고 2$^{110.7}$ CPU 시간을 통해 128비트 키정보를 얻는 것이다.다.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제15권1호
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• pp.195-215
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• 2021

Multipath Transport Control Protocol (MPTCP) is a transport layer protocol that enables multiple TCP connections across various paths. Due to path heterogeneity, it incurs more energy in a multipath wireless network. Recent work presents a set of approaches described in the literature to support systems for energy consumption in terms of their performance, objectives and address issues based on their design goals. The existing solutions mainly focused on the primary system model but did not discourse the overall system performance. Therefore, this paper capitalized a novel stochastically multipath scheduling scheme for data and path capacity variations. The scheduling problem formulated over MPTCP as a stochastic optimization, whose objective is to maximize the average throughput, avoid network congestion, and makes the system more stable with greater energy efficiency. To design an online algorithm that solves the formulated problem over the time slots by considering its mindrift-plus penalty form. The proposed solution was examined under extensive simulations to evaluate the anticipated stochastic optimized MPTCP (so-MPTCP) outcome and compared it with the base MPTCP and the energy-efficient MPTCP (eMPTCP) protocols. Simulation results justify the proposed algorithm's credibility by achieving remarkable improvements, higher throughput, reduced energy costs, and lower-end to end delay.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제32권3호
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• pp.118-125
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• 2021

Objectives: Childhood adversity is a risk factor for anxiety symptoms, but it affects anxiety symptoms in attention-deficit/hyperactivity disorder (ADHD). The current study aimed to examine the association between childhood adversity and anxiety symptoms in participants with and without ADHD. Methods: Data were obtained from a school-based epidemiological study of 1017 randomly selected children and adolescents. The ADHD and non-ADHD groups were divided using the Diagnostic Interview Schedule for Children Predictive Scale (DPS). The DPS was also used to assess comorbidities such as anxiety and mood disorders. The childhood adversities were assessed using the Early Trauma Inventory Self Report-Short Form, and the anxiety symptoms were assessed using the Screen for Child Anxiety Related Disorders. Linear and logistic regression models were used to investigate the association between childhood adversity and anxiety in the ADHD and non-ADHD groups with adjustments for age and sex. Results: This study found that the ADHD group did not show any significant association between anxiety symptoms and childhood adversities, whereas the non-ADHD group always showed a significant association. In a subgroup analysis of the non-ADHD group, the normal group without any psychiatric disorders assessed with DPS demonstrated a statistically significant association between childhood adversities and anxiety symptoms. These results were consistent with the association between childhood adversities and anxiety disorders assessed using DPS, as shown by logistic regression. Conclusion: The association between anxiety symptoms and childhood adversities statistically disappears in ADHD; ADHD may mask or block the association. Further longitudinal research is necessary to investigate this relationship.

• 한국정보통신학회논문지
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• 제25권1호
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• pp.108-114
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• 2021

무인 항공기 탑재장비 점검을 위한 통합 점검 장치는 항공기가 임무 수행을 위해 비행 전, 그리고 비행 임무를 완료하고 착륙 이후 항공기에 탑재되어 있는 장비들의 상태를 점검하기 위한 장치이다. 본 논문에서는 무인 항공기에 탑재되어 있는 전자장비에 대하여 점검자가 수동으로 장비의 상태를 점검하고, 점검 결과를 시현하는 방법과 점검자의 개입 없이 자동으로 장비의 상태를 점검할 수 있는 자동 점검 기술에 대해 기술하였다. 또한 설계된 통합 점검 장치는 점검 결과를 보고서의 형태로 출력하여 사용자가 쉽게 결과를 확인 할 수 있도록 하여 무인항공기의 고장 유무를 판단하기 용이할 뿐 아니라, 자동 점검 기능을 사용함으로써 항공기 점검자의 업무량을 줄이는데 효과적인 방법이다.

• 한국전자거래학회지
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• 제26권1호
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• pp.127-140
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• 2021

최근 센서 측정 데이터, 구매이력 등과 같이 시간 정보를 포함하는 시퀀스(sequence) 데이터가 다양한 응용에서 발생되고 있다. 주어진 시퀀스들 중 다른 시퀀스들과 매우 상이한 이상(anomalous) 시퀀스를 탐지하는 기법들은 지금까지 많이 연구되어왔으나 이들 대부분은 주로 시퀀스 내 원소들의 순서만을 고려하여 이상 시퀀스를 찾는다는 한계가 있다. 따라서 본 논문에서는 원소들의 순서와 원소들 간의 시간 간격 모두를 고려하는 새로운 이상 시퀀스 탐지 기법을 제안한다. 본 논문에서 제안하는 방법은 확장된 LSTM 오토인코더 모델을 사용한다. 이 모델은 시퀀스를 해당 시퀀스 내 원소들의 순서와 시간 간격 모두를 효과적으로 학습할 수 있는 형태로 변환하는 층을 추가로 가진다. 제안방법은 확장된 LSTM 오토인코더 모델로 주어진 시퀀스들의 특징을 학습한 뒤, 해당 모델이 잘 복원하지 못하는 시퀀스를 이상 시퀀스로 탐지한다. 본 논문에서는 정상 시퀀스와 이상 시퀀스를 혼합한 가상 데이터를 사용하여 제안 방법이 전통적인 LSTM 오토인코더만을 사용하는 방법과 비교하여 100%에 가까운 정확도를 나타냄을 보인다.