• Journal of Preventive Medicine and Public Health
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• 제40권2호
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• pp.162-168
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• 2007

Objectives : This prospective population-based cohort study was conducted to evaluate the risk factors of cognitive impairment and the degree of cognitive function change through a 5-year follow-up. Methods : The baseline and follow-up surveys were conducted in 1998 and 2003, respectively, Among 176 subjects who had normal cognitive function in the baseline study, 136 were followed up for 5 years. The cognitive function was investigated using the Korean version of the Mini-Mental State Examination (MMSE-K). The collected data were analyzed using SPSS and Stata. Results : Of the 136 subjects analyzed, 25 (18.4%) were cognitively impaired. Old age and low social support in the baseline survey were risk factors for cognitive impairment after 5 years. In the generalized estimating equation for 128 subjects except severe cognitive impairment about the contributing factors of cognitive function change, the interval of 5 years decreased MMSE-K score by 1.02 and the cognitive function was adversely affected with increasing age, decreasing education and decreasing social support. Conclusions : Although the study population was small, it was considered that the study results can be used to develop a community-based prevention system for cognitive impairment.

• 한국정밀공학회지
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• 제28권12호
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• pp.1425-1433
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• 2011

We investigated an early rehabilitation training system that increase the intensity of patient rehabilitation training to shorten the time it takes for patients to progress to a secondary rehabilitation training stage by allowing patients incapable of self-ambulation. It consisted of tilting bed, unstable platform using strong springs and training program for lower limb rehabilitation. We performed experimental study on the muscular activities of tibialis anterior(TA), soleus(SO), gastrocnemius(GA) in the lower extremities during training of straight line, circle, quardrangle pattern during tilting angle of $30^{\circ}$, $60^{\circ}$. The muscle activities were higher during tilting angle of $30^{\circ}$ than $60^{\circ}$. In straight line pattern, the muscle activities were higher by SO, GA and TA during medio-lateral direction, however, by TA, SO and GA during anterio-posterior direction. In circle and quardrangle pattern, the muscle activities were higher by TA, SO and GA during clockwise and counterclockwise direction. The results indicate that the early rehabilitation training system could be applied to improve the lower extremity muscular strength for elderly and patients, especially, stroke.

• 한국식품영양과학회지
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• 제44권1호
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• pp.49-56
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• 2015

본 연구는 지역사회에서 거주하고 있는 재가노인을 대상으로 삼킴장애 위험군을 선별하여 위험 실태를 파악하고 관련인자를 조사하고자 하였다. 서울, 경기 및 충북 지역에 거주하는 65세 이상 재가노인 419명을 대상으로 2012년 9월에서 12월까지 일대일 면접방법으로 설문자료를 수집하였다. 주요 연구 결과는 다음과 같다. 첫째, 전체 응답자 가운데 과반수(53.50%)가 삼킴장애 위험군으로 판정되었고 삼킴장애 위험점수는 평균 13.17점으로 국내외 선행연구보다 높은 수준이었다. 둘째, 노인의 삼킴장애 위험도는 65~74세군보다 75세 이상군에서 높았고, 의치를 하는 경우와 일상생활에서 독립성이 떨어지는 경우에 유의하게 높았다. 셋째, 삼킴장애 위험군과 비위험군에서 노인의 식품섭취 문제와 그에 따른 향후 섭취 문제 위험 여부를 조사한 결과 삼킴장애 위험군은 비위험군보다 식욕부진, 식사량 감소, 잦은 결식, 입맛이 나쁘다고 응답한 경우가 많았으며 이에 따라 향후 섭취 문제 위험도가 유의하게 높은 것으로 나타났다. 결론적으로 국내 재가노인의 삼킴장애 실태는 간과하기 어려운 수준이며 향후 지역사회의 다양한 환경에 있는 노인들을 대상으로 연구가 확대되어야 할 것이다.

• Hip & pelvis
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• 제30권4호
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• pp.269-275
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• 2018

Purpose: The purpose of this study is to describe a method of inserting cement in the femoral head before fixation with dynamic hip screw to prevent screw cut out due to osteoporosis and to evaluate its clinical outcome in these patients. Materials and Methods: In this prospective study, 30 patients aged 60 years and older with intertrochanteric fracture were included. Bone mineral density was measured. After reaming of the femoral head and neck with a triple reamer and polymethyl methacrylate, bone cement was introduced into the femoral head using a customized nozzle and a barrel fitted on a cement gun. A Richard screw was inserted and the plate was fixed over the femoral shaft. Patients were mobilized and clinical outcomes were rated using the Salvati and Wilson's scoring system. Results: More patients included in this study were between 66 and 70 years old than any other age group. The most common fracture according to the Orthopaedic Trauma Association classification was type 31A2.2 (46.7%). The T-score was found to be $-2.506{\pm}0.22$ (mean${\pm}$standard deviation); all patients were within the range of -2.0 to -2.8. The duration of radiological union was $13.67{\pm}1.77$ weeks. Salvati and Wilson's scoring at 12 months of follow up was $30.96{\pm}4.97$. The majority of patients were able to perform their normal routine activities; none experienced implant failure or screw cut out. Conclusion: Bone cement augmentation may effectively prevent osteoporosis-related hardware complications like screw cut out in elderly patients experiencing intertrochanteric fractures.

• 한국치위생학회지
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• 제19권1호
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• pp.65-78
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• 2019

Objectives: This study was conducted to characterize the impact of cognitive function and oral health status on mastication in senior citizens, ${\geq}65$ years of age, using senior centers in the city of Wonju, South Korea. Methods: A cross-sectional study consisting of a simple oral examination and survey questionnaires was performed in 154 individuals. General characteristics, subjective masticatory function, objective masticatory function, cognitive function, and oral health status were collected as variables. Correlation and multiple linear regression analyses were conducted. A p-value of <0.05 was considered to be statistically significant. Results: The subjective masticatory function was scored using the 5-point Likert scale. When subjective masticatory function was analyzed in groups according to cognitive function, the mean subjective masticatory function scores were 4.31, 4.09, and 3.29 in the normal group (cognitive score of ${\geq}16$), suspected dementia group (cognitive score of 1215), and mild dementia group (cognitive score of ${\leq}11$), respectively. Thus, subjective masticatory function decreased along with decreasing cognitive function. When cognitive function, subjective masticatory function, and objective masticatory function were compared with indicators of oral health status (number of functional teeth, oral dryness), subjective masticatory function exhibited a significant positive correlation with objective masticatory function (r=0.635, p<0.01), cognitive function (r=0.292, p<0.01), and total number of functional teeth, including prosthetic appliances (dentures) (r=0.305, p<0.01). According to the regression analysis, age, sex, number of functional teeth, and cognitive function affected subjective masticatory function. Conclusions: The results of this study revealed that age, sex, number of functional teeth, and cognitive function affected subjective masticatory function, whereas oral dryness did not. Therefore, dental professionals must consider subjective masticatory function when providing oral care in senior patients with low cognitive function.

• Nutrition Research and Practice
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• 제15권2호
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• pp.173-186
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• 2021

BACKGROUD/OBJECTIVES: Alzheimer's disease (AD) is the most common cause of dementia in the elderly. Due to the increased incidence of dementia, there is a corresponding increase concerning the importance of AD. In this study, we investigated the protective effects conferred by Zizyphus jujuba (Zj) and Zizyphus jujuba fermented by yeast (Zj-Y), on cognitive impairment in an AD mouse model. MATERIALS/METHODS: AD was induced by injecting amyloid beta25-35 (Aβ25-35) in ICR mice, and subsequently 200 mg/kg Zj or Zj-Y was administered daily for 14 days. The cognitive ability of AD mice was observed through behavioral experiments in T-maze, novel object recognition, and Morris water maze tests. We subsequently measured the levels of malondialdehyde (MDA), nitric oxide (NO), aspartate aminotransferase, and alanine aminotransferase in either tissues or serum. RESULTS: In behavioral tests, deterioration was revealed in the short- and long-term learning and memory functions in the Aβ25-35-injected control group compared to the normal group, indicating that Aβ25-35 injection impairs cognitive functions. However, administration of Zj and Zj-Y improved cognitive function in mice, as compared to the Aβ25-35-injected control mice. In addition, the Aβ25-35 induced elevations of MDA and NO in the brain, kidney, and liver were suppressed after exposure to Zj and Zj-Y. Especially, Zj-Y showed stronger scavenging effect against MDA and NO, as compared to Zj. CONCLUSIONS: Results of the present study indicate that Zj-Y exerts a protective effect on cognitive impairment and memory dysfunction, which is exerted by attenuating the oxidative stress induced by Aβ25-35.

• 한국엔터테인먼트산업학회논문지
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• 제14권8호
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• pp.391-396
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• 2020

본 연구는 하지 사슬운동 유형이 라이프케어먼트를 위한 운동 수행능력에 미치는 영향을 알아보고자 하였다. 이를 위해 전라북도 소재 J대학의 정상 성인 여성 20명이 참여하여 두 가지 유형의 사슬운동을 적용하여 배곧은근의 활성도와 균형 능력에 대한 운동 효과 차이를 검사하였다. 참여자들은 각 유형의 운동에 대해 4주 동안 운동을 시행하도록 하였고 그룹 내 및 그룹 간 차이를 비교하기 위해 대응표본 t-검정과 독립 표본 t- 검정을 이용해 분석하였다. 연구 결과, 근육활성도와 균형 기능에서 닫힌사슬 운동이 열린사슬 운동보다 더 효과적이라는 것을 알 수 있었다. 따라서 임상 치료 환경에서 환자에게 하지 운동기능 향상을 위해 사슬운동을 적용할 경우에 닫힌사슬 운동 적용이 보다 효과적일 수 있음을 제시한다.

• 대한본초학회지
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• 제28권3호
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• pp.95-106
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• 2013

Objectives : The researcher investigated the anti-obesity effect of Alismatis Orientale Rhizoma(AP) water extract in mice fed a high fat diet and focused on the analysis of local area adipose tissue. Methods : Male ICR mice were divided into three groups, which were fed either a normal AIN diet, a 45% high fat diet (CT group), or a high fat diet and orally administration with a concentrations of 100 mg/kg (AP100 group) and 300 mg/kg body weight (AP300 group) for eight weeks. Results : As compared with CT group, AP100 group showed significant reductions in absolute weight of liver. As compared with CT group, AP100 group and AP300 group showed significant reductions in weight gain and relative weight of total fat. AST, triglyceride, total-cholesterol levels from the AP 100 group and 300 group were significantly lower than those of the CT, and ALT, LDL-cholesterol levels from the AP 100 group was significantly lower than those of the CT. But serum HDL-cholesterol levels from the AP 100 group and 300 group were significantly higher than those of the CT. And serum adiponectin levels from the AP 100 group was significantly higher than those of the CT. In result of real time PCR, all mRNA expression(PEPCK, G6Pase, PGC-$1{\alpha}$ and $ERR{\gamma}$) of two experimental groups were significantly decreased compared to those of CT group. The treatment with AP on local abdominal area made a fat cell size lessen on the fat tissue in the abdominal cavity and subcutaneous area. Conclusions : These results suggest that AP has an anti-obesity effect and the effect is mediated by inhibition of fat gain.

• 한국재난정보학회 논문집
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• 제18권3호
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• pp.433-443
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• 2022

연구목적: 본 논문에서는 스마트 디바이스의 높은 보급률을 활용하여 근감소증을 추정 및 예측하는 딥러닝 알고리즘을 제안과 연구를 수행한다. 연구방법: 딥러닝 학습을 위해 스마트 디바이스에 내장된 관성센서를 활용하여 실험 데이터를 수집하였다. 데이터를 수집하는 테스트용 어플리케이션 구현하여 '정상'과 '비정상'걸음과 '달리기', '낙상', '스쿼트' 자세의 5 가지 상태를 구분하여 데이터를 수집하였다. 연구결과: LSTM, CNN, RNN model 사용 시 예측 정확도를 분석했고 CNN-LSTM 융합형 모델을 활용하여 이진분류 정확도 99.87%, 다중 분류 92.30%의 정확도를 보였다. 결론: 근감소증이 있는 사람의 경우 걸음걸이의 이상이 생긴다는 점에 착안하여 스마트 디바이스를 활용한 연구를 진행하였다. 본 연구를 활용하여 근감소증으로 인해 생기는 재난안전을 강화 할 수 있을 것이다.

• 한국융합학회논문지
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• 제13권5호
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• pp.357-363
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• 2022

한국은 저출생 현상과 급속한 고령화로 인하여 노인돌봄 위기에 처해 있다. 2008년 노인장기요양보험이 본격적으로 실시되면서 노인돌봄의 사회화가 이루어지게 되었으나 다양하지 못한 서비스 선택권, 맞춤형 돌봄의 부족, 커뮤니티 케어의 불안정함 등으로 돌봄의 공백은 아직 사회문제로 남아있다. 또한 고령화의 진전에 따라 치매유병율의 증가는 새로운 사회위기이다. 이러한 상황에서 복지기술은 부족한 자원과 증가하는 수요의 공백을 메꾸어줄 미래의 중요한 대안이다. 본 논문에서는 지역에서 다양하게 제공되고 있는 치매서비스를 경험한 바 있는 경증치매노인 집단그룹면접, 치매고위험군 집단그룹면접을 통해 복지기술에 대한 친밀성, 접근성, 치매예방방안 등을 파악하였다. 치매 정도에 따른 차이는 있으나 두 그룹 모두 복지기술을 활용한 치매서비스에 관심이 높았다. 특히, 일상생활에서 자립적 훈련은 친밀한 도구인 TV나 전화를 활용하는 방안이 제시되었고 경증치매노인군의 경우 데이케어센터에서 기술활용을 위한 도움서비스와 가정 내 연계방안의 필요성이 제시되었다.