• Investigative Magnetic Resonance Imaging
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• v.21 no.4
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• pp.199-209
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• 2017

Purpose: Caffeine is the most widely consumed psychostimulant. It is often adopted as a tool to modulate brain activations in fMRI studies. However, its pharmaceutical effect on task-induced deactivation has not been fully examined in fMRI. Therefore, the purpose of this study was to examine the effect of caffeine on both activation and deactivation under sustained attention. Materials and Methods: Task fMRI was acquired from 26 caffeine naive healthy volunteers before and after taking caffeine pill (200 mg). Results: Statistical analysis showed an increase in cognition-load dependent task activation but a decrease in load dependent de-activation after caffeine ingestion. Increase of attention and memory task activation and its load-dependence suggest a beneficial effect of caffeine on the brain even though it has no overt behavior improvement. The reduction of deactivation by caffeine and its load-dependence indicate reduced facilitation from task-negative networks. Conclusion: Caffeine affects brain activity in a load-dependent manner accompanied by a disassociation between task-positive network and task-negative network.

• Physical Therapy Korea
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• v.15 no.4
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• pp.70-79
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• 2008

The purpose of this study was to find out the effects of electroencephalograph (EEG) power and coherence on cognitive function in normal elderly, non-demented elderly with mild cognitive impairment, and demented elderly during working cognition tasks. Forty elderly women (19 demented elderly, 10 non-demented elderly with mild cognitive impairment, 11 norma1 elderly) participated in this study, All subjects performed working cognition tasks with Raven's CPM while EEG signal was recorded, EEGs were measured continuously at rest and during the working cognition task. EEG power and coherence was computed over 21 channels: right and left frontal, central, parietal, temporal and occipital region. We found that there were more correct answers among normal elderly women than in other groups Owing the working cognition task, ${\Theta}$ wave at Fp1, Fp2 and F8, a wave at Fp2, ${\beta}$ wave at Fp1, Fp2. F4 and F8 of the frontal region was increased significantly in the demented elderly group. On the other hand. ${\Theta}$ wave at Fp1, Fp2 and F7, ${\beta}$ wave at Fp1, Fp2, F3 and F7 of the frontal region was increased significantly in the group of non-demented elderly with mild cognitive impairment. In contrast. in the normal elderly group, all of the ${\Theta}$ wave and ${\beta}$ wave at Fp1, Fp2, F3, F4, F7 and F8 of the frontal region (except ${\beta}$ wave at F3) was increased significantly, These results suggest that the nerves in prefrontal and right hemisphere regions were most active in the demented elderly group during problem solving, and the nerves in the prefrontal and left hemisphere lobe were most active in the group of non-demented elderly with mild cognitive impairment. In contrast, me majority of nerves in the frontal region were active in the normal elderly group.

• Journal of Korean Biological Nursing Science
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• v.13 no.2
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• pp.185-192
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• 2011

Purpose: The purpose of this study was to investigate the cognition, balance, quality of life and the correlation of these variables in the elderly. Methods: This study was a descriptive survey research. The samples were 86 and variables were measured by structured questionnaire and physical balance movements. The data were analyzed with %, t-test, ${\chi}^2$-test, ANOVA, Pearson correlation by SPSS ver. 19.0 for windows. Results: The cognition score was 24.02 which means within normal limits. The balance score was 11.83 and the score of QOL was 82.67 which were similar to other research results. There were significant differences in the balance (p<.001) and the QOL (p=.004) by the cognition level. A significant correlation among the cognition, balance and the QOL was observed. Conclusion: The cognition was closely related with the balance and the QOL. The cognitive stimulus and the balance exercise could help the improvement of QOL in the elderly.

• Proceedings of the Korean Society for Emotion and Sensibility Conference
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• 2003.11a
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• pp.81-83
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• 2003

The present study attempted to observe what changes the supply of highly concentrated(30％) oxygen cause to people's ability and cerebrum lateralization of verbal cognition, compared to air of normal oxygen concentration(21％). The experiment consisted of two runs, one for verbal cognition test with normal air(21％ of oxygen) and for verbal cognition test with more oxygen in the air(30％ of oxygen). Functional brain images were taken form 3T MRI using the single-shot EPI method. There were more activations observed at the occipital, parietal, temporal, and frontal lobes, but there were no changes in cerebrum lateralization with 30％ oxygen administration. The result of task performance showed the accuracy increased at 30％'s concentration of oxygen rather than 21％'s. It is concluded that the positive effect on the verbal cognitive performance level by the highly concentrated oxygen administration was due to changeless increase of left and right cerebrum activation.

• Journal of East-West Nursing Research
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• v.16 no.2
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• pp.131-137
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• 2010

Purpose: The purpose of this study was to investigate the relationship between depression status and cognitive function in the community female aged. Methods: This was a descriptive study. Data were collected using individual-based interviews from 120 senior female residents in the Hall for the aged in the city of S. The length of time for data collection was from June 18 to 29, 2007. The tool of data collection was Korean Version of Mini-Mental State Examination (Kwon & Park, 1989), Short-form Geriatric Depression Scale (Bae, 1996). Results: Depression & cognition showed significant differences according to age, regular exercise. The depression group scored significantly lower than the normal group in total score of cognition, orientation, memory recall. Conclusion: It is necessary to prepare the composite programs, which can improve not only cognition but depression in the community female aged.\

• Journal of Society of Preventive Korean Medicine
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• v.7 no.2
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• pp.1-12
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• 2003

The study was conducted to evaluate the difference of life style, subjective symptoms and health cognition depending on the Sasang Constitution in the industrial workers. The results were as follows ; Constitutional distribution among exposed group were Tae-eum In(38.4%), So-eum In(35.2%), and So-yang In(26.4%) and it was turned out that Tae-eum In took a higher portion of Sasang constitution than other constitutions in technician workers. 'Exercise' and 'Obesity' were found most in Tae-eum In, In So-eum In there were many 'Normal' weight and 'Having digestive disorders' were found most in So-eum In. There were no significant difference in the health cognition among the constitutions. The closer to 'normal' weight, the higher prevalence in 'having' concern about health condition and the more 'normal' condition in sleeping, the higher prevalence of 'having' self-confident in present health.

• Journal of the Korean Society for Precision Engineering
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• v.21 no.8
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• pp.180-187
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• 2004

The present study attempted to investigate the effects of supply of highly concentrated (30%) oxygen on human ability of visuospatial cognition and cerebrum lateralization. compared to air of normal oxygen concentration (21%). The experiment consisted of two runs, one fur visuospatial cognition test with normal air (21% of oxygen) and for visuospatial cognition test with more oxygen in the air (30% of oxygen). Each run was composed of four blocks and each block included eight control tasks and five visuospatial tasks. Functional brain images were taken from 3T MRI using the single-shot EPI method. The result of task performance showed the accuracy increased at 30%＇s concentration of oxygen rather than 21%＇s. There were more activations observed at the left and right hemisphere, but there was decrease cerebrum lateralization with 30% oxygen administration. Thus, it is concluded that the positive effect on the visuospatial cognitive performance level by the highly concentrated oxygen administration was due to increase of cerebrum activation and decrease of cerebrum lateralization

• Journal of Biomedical Engineering Research
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• v.26 no.1
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• pp.1-7
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• 2005

This study aimed to investigate the hypothesis that administration of the air with 30% oxygen compared with normal air (21% oxygen) enhances cognitive functioning through increased activation in the brain. Seventeen college students (right­handed, average age of 24.3) were selected as subjects for this study. An oxygen supply equipment that provides 21% and 30% oxygen at a constant rate of 8L/min was developed. In order to measure the performance level of visuospatial and verbal cognition, two psychological tests were developed. The experiment consisted of two runs, one for cognition task with normal air (21% oxygen) and the other for cognition task with hyperoxic air (30% oxygen). Visuospatial and verbal tasks were presented while brain images were scanned by a 3T fMRI system using the single-shot EPI method. The results showed that there was an improvement in performance and also increased activation in several brain areas in the higher oxygen condition. These results suggest that while performing cognitive tasks, high concentrations of oxygen administration make oxygen administration sufficient, thus making neural network activate more, and the ability to perform cognitive tasks increase.

• 한국노년학
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• v.37 no.2
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• pp.431-444
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• 2017

This study identified effect size of cognition improvement programs developed for normal elderly in Korea. By searching four databases, 9,624 studies published from 2000 to 2016 were identified. Finally, 14 studies which satisfied the inclusion criteria were selected for meta-analysis. Quality assessment of included studies was conducted using controlled trial checklist of Scottish Intercollegiate Guidelines Network. R version 3.3.2 (2016-10-31) with "meta" and "metafor" package was used to calculate effect sizes, identify the reasons of heterogeneity, and check publication bias. Total effect size of cognition improvement program was middle (SMD=0.759, p<.001, $I^2=34%$). For heterogeneity, moderator analysis was executed and combined program with exercise had the largest effect size (SMD=1.231, p<.001, $I^2=40.8%$). Publication bias was exist by funnel plot and Egger 's regression test, but trim and fill analysis showed that there was no serious error to reverse study results. Therefore, Combined program with exercise for the normal elderly was expected to improve the cognitive function of the normal elderly.

• The Journal of the Korea institute of electronic communication sciences
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• v.11 no.2
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• pp.215-222
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• 2016

Research on gait recognition and its use is actively underway. This study suggests a method to recognize abnormal gaits of pedestrians. The purposes of the existing research to recognize normal steps are to measure physical activities and to validate people by their walks, but the purpose to recognize abnormal steps in this study is to insure the safe life of pedestrians. There are situations in which pedestrians are unaware of themselves vulnerable and can not ask for help. The purpose of this research is that even if pedestrians are unaware of themselves and there are no spontaneous requests for helps, it is intended for them to escape from dangers and difficulties by adopting the recent IOT technology. Hence, this study analyzes normal pace of pedestrians using the triaxial acceleration sensors, and takes ranges of their normal walking. And then, the steps of pedestrians are measured using the triaxial acceleration sensors, contrasted with their normal walking ranges, and determine whether their steps are normal or not. When it is out of the state for normal paces, a method to determine as abnormal paces is suggested.