• Medical Lasers
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• 제9권1호
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• pp.39-43
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• 2020

Background and Objectives Breast reconstruction has the advantage of reducing the loss of the body image of patients after mastectomy surgery, and also improving the quality of the social and sexual life of breast cancer patients. However, in surprising and unfortunate number of patients, acute postoperative pain persists beyond the normal course of postsurgical recovery. We set out to investigate the effect of local dynamical micro-massage (LDM) treatment for achieving pain relief and reducing other postoperative complications. Materials and Methods We performed a retrospective analysis on 58 patients who underwent LDM treatment for postoperative pain management at Soonchunhyang University Bucheon Hospital between February 2017 and June 2019. Those patients who complained of persistent postoperative pain, which was uncontrollable with medication, were treated with LDM. The degree of pain and discomfort with contracture were recorded using numerical rating scale (NRS) scoring system with numbers from 0 to 10 ('none' to 'worst'). Results The median NRS score of pain was reduced by 62.3% from the start to the end of LDM treatment (p<0.001). Further, the NRS score of discomfort with contracture was reduced 66.0% (p<0.001). There was no complication related to the LDM treatment. Conclusion Dual-frequency ultrasound LDM can be an effective therapeutic option for persisting pain after breast reconstruction surgery. It was also effective in improvement of discomfort with contracture and erythema of the surgical wound.

• 한국임상수의학회지
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• 제39권1호
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• pp.16-22
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• 2022

A 12-year-old spayed female beagle dog was presented with pollakiuria and stranguria. Abdominal ultrasonography identified irregular a marginated, hyperechoic mass in the urethra and trigon area of the bladder. Computed tomography (CT) revealed a heterogeneous mass in the trigone area leading to a urethra. There was no evidence of regional or distant metastasis. Cytologic analysis suspected transitional cell carcinoma (TCC). The patient was treated with piroxicam, mitoxantrone, and once weekly fractionated radiation therapy (RT) with volumetric modulated arc therapy (VMAT). A follow-up CT scan at 6 months after RT revealed a reduction in tumor size. At 17 months after the start of RT, the patient became severely anorectic and lethargic. Ultrasound examination revealed a hyperechoic mass in the apex area of bladder while the trigone area of the bladder and urethra appeared normal. Multiple hypoechoic nodules of various sizes were found in the liver and spleen. The patient was humanely euthanized at the request of the owner. A combination of piroxicam, mitoxantrone, and hypofractionated RT with VMAT protocol was well tolerated. This case described tumor response and survival time of a canine TCC treated with piroxicam, mitoxantrone, and once weekly palliative RT using computer-assisted planning and VMAT.

• 정보관리학회지
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• 제39권2호
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• pp.325-346
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• 2022

뉴노멀 시대로 특징지어지는 현대사회가 COVID-19 팬데믹을 겪으면서 도서관에 많은 변화를 요구하였고, 도서관계는 이에 대하여 선제적으로 그리고 다각적으로 대응하였다. 본 연구는 팬데믹과 같은 새로운 환경이 사서들이 인식하는 도서관 운영정책 우선순위를 변화시킬 것이라고 보고, 2020년 팬데믹이 시작되는 시점과 2022년 팬데믹이 정점을 지난 시점에서 도서관 운영정책 중요도를 쌍대비교 분석을 통하여 파악하였고 그 차이를 비교·분석하였다. 1차 조사에서는 도서관경영, 도서관 서비스 관련 운영정책 영역을 중요하게 여겼다면, 2차 조사에서는 인적자원과 정보자원에 관련된 운영정책 영역을 보다 중요하게 인지하고 있었다. 또한, 전체 영역 상위 5위에 인적자원과 관련된 3개의 세부 운영영역과 자료구입 예산, 이용자만족도 기반의 정책이 포함되었다. 따라서 공공도서관은 새로운 패러다임에 빠르게 적응하면서도 지속가능한 도서관 서비스를 제공하기 위해서는 지속적인 인적자원에 대한 투자, 충분하고도 다양한 형태의 정보자원 구축, 그리고 이용자 맞춤 정책 수립 등을 우선적으로 수행해야 할 것이다.

• 한국전자통신학회논문지
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• 제17권4호
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• pp.617-624
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• 2022

V2X를 탑재한 소형 전기운송차는 기존 자동차의 운전시스템에 더 많은 정보와 기능을 제공할 수 있다. V2X 기술의 주요 요소는 V2V(자동차 대 자동차), V2N(자동차 대 네트워크), V2I(자동차 대 인프라) 등이 있다. 본 연구는 외부장비와 연계되는 VI형 E-PTO를 설계하고 구현하는 것으로 E-PTO는 DC/DC 변환기, DC/AC 변환기, 배터리 양방향 충전시스템 등으로 구성된다. 또한 구동을 위한 기기와 제어시스템을 구현하였다. 기동/정지 및 정상상태 운전 통한 VI형 E-PTO 구성부품에 대한 시험결과는 100ms 이내 회복시간과 순간 전압변동율 10%의 허용 가능한 요건을 충족하였다.

• 대한본초학회지
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• 제38권2호
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• pp.27-34
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• 2023

Objectives : Currently, the benign prostatic hyperplasia (BPH) is one of the most common urogenital disorder in old men. We were performed to determine the effects of abietic acid (AC), component of pine resin, in benign prostatic hyperplastic Sprague-Dawley rat (SD rat) induced by testosterone injection (IP). Methods : We monitored body weights in SD rat at start and end date of experiment. After end of experiment, the prostate weights were measured in SD rats. Glutamic oxaloacetic transaminase (GOT) and glutamic pyruvic transaminase (GPT) levels was performed in serum. And we determined the 5-alpha reductase Ⅱ activity, testosterone levels, and dihydrotestosterone levels in prostate tissue and serum using ELISA kit. Results : As results, the prostate wights were increased in BPH group compared to normal group and were decreased in fina, AC30, and AC 50 groups, respectively. Serum GOT levels were decreased in AC50 group compared to BPH group. And Serum GPT levels of AC30 and AC50 groups were lower than BPH group. In addition, the 5-alpha reductase Ⅱ activity, testosterone levels, and dihydrotestosterone levels were decreased the fina, AC10, AC30, and AC 50 groups contrast to the BPH group. Furthermore, 5-alpha reductase Ⅱ activity, testosterone levels, and dihydrotestosterone levels were decreased dose dependent in AC groups compared to BPH group. Conclusion : These results suggest that AC could be used as a potential material for the treatment of BPH by decreasing the androgen levels in benign prostatic hyperplasia model rats.

• 한국작물학회지
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• 제25권2호
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• pp.64-67
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• 1980

참깨품종 '수원9호'의 만식재배시 적정수확기를 결정하기 위하여 성숙후기로부터 주기적으로 sampling하여 수량발연항목들을 조사하고 삭수분함량, 개삭율 및 조직노화상태를 기록하였다. 아울러 작물건조제 Diquat을 살포하여 그의 효과와 이용가능성을 검토하였다. 1. 개체당 종실수량과 종실수는 9월 18일 수확에 이미 최대에 달하있고, 이들은 그후 점차 감소하였으나 천입중은 9월 29일 수확기까지 증가하는 추세이였다. 2. 수확기가 늦어질수록 삭수분함량 감소하고 반면 개삭율은 증가하였다. 삭의 열개는 수분함량이 70% 이하로 떨어졌을 때 발생하였고 탈입에 따른 수량저하 급격히 증대되는 시기는 수분함량이 65% 이하이고 개삭률이 50 %이상인 때부터이었다. 3. 적정수확기는 종실수가 최대로 확보되고 삭수분함량이 70%이하로 떨어질 때부터이며 엽의 황화는 _상위절까지 지전되고 50%삭이 황화되였을 때에 해당하였다. 4. 엽의 탈락이후의 천입중의 증가는 삭의 storage pool로서의 기능으로 보여지며 삭조직중의 약 5%가량이 종실중 증가에 기여하였다. 5. Diquat을 식물체에 살포하였을 때 5 일후에 삭수분함량은 40 % 이하로 떨어지고 7일후에는 90% 이상 개삭이 일어났다. 이는 포장상태 참깨보다 2주이상 건조를 촉진시켰으며 균일화의 효과가 있었다.

• International Journal of Computer Science & Network Security
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• 제24권5호
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• pp.135-155
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• 2024

Urban public health monitoring in smart cities focuses on the control of conditions and health challenges in urban environments. Considering the rapid spread of diseases and pandemics, it is important for health authorities to trace people carrying the virus. In smart cities, this tracing must be interoperable and intelligent, especially in indoor surfaces characterized by small distances between people. Therefore, to fight pandemics, it is necessary to start with the already-existing digital equipment of the Internet of Things, such as connected objects and smartphones. In this study, the developed system is employed to provide a social IoT network and suggest a strategy which allows reliable traceability without threatening the privacy of users. This IoT-based system allows respecting the social distance between persons sharing public services in smart cities without applying smartphone applications or severe confinement. It also permits a return to normal life in case of viral pandemic and ensures the much-desired balance between economy and health. The present study analyses previous proposed social distance systems then, unlike these studies, suggests an intelligent and distributed IoT based strategy for positioning students. Two scenarios of static and dynamic optimization-based placement of Bluetooth Low Energy devices are proposed and an experimental study shows the contribution and complementarity of the introduced contact tracing strategy with the applications on smartphones.

• 한국임상수의학회지
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• 제28권2호
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• pp.225-231
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• 2011

본 연구의 목적은 FSH 분비 조절에 있어서 각각 다른 progesterone (P) 농도가 Pulse 또는 Surge 형태의 분비 패턴에 어떤 영향을 미치는가를 탐구한다. 선행된 연구에서 LH surge는 난포기 (follicular phase)에서 보이는 P 농도에서만 발현되었고 황체기(luteal phase) 또는 아황체기(subluteal phase) P 농도에서는 완전히 억제되었다. 또한 LH pulse 분비는 황체기 P농도에서만 시간 의존적으로 감소되었으나 난포기 또는 아황체기 농도에서는 높은 빈도로 유지되었다. 즉 아황체기 P농도 (스트레스, 황체형성부전에서 발생)는 LH surge는 억제시키나 LH pulse 조절에는 아무런 영향을 마치지 않았다. 이 결과를 바탕으로 FSH surge 및 pulse 분비패턴을 알아보기 위해 난소가 제거된 Shiba 염소를 이용하여 인위적으로 난포기, 아황체기, 기능성황체기의 P 농도 및 estradiol(E) 농도를 유도하였다. 스테로이드 호르몬 농도의 변화를 알아보기 위해 매일 혈액을 채취하였으며, LH pulse 용 혈액은 10분 간격으로 8시간 동안 Day 0, Day 3, Day 7 (Day 0: P packet 이식 직전)에 연속채혈을 실시하고, LH surge 분비패턴은 Day 8에 16시간 estradiol를 3 ${\mu}g/h$ 농도로 주사하고, 52시간 동안 2시간 간격으로 채혈을 실시했다. 그 결과 유도된 P 농도는 염소의 정상적 발정주기에서 볼 수 있는 난포기(<0.1 ng/ml), 아황체기($1.1{\pm}0.1$ ng/ml), 황체기 ($3.3{\pm0.1}$ ng/ml) 수준의 농도로 유도되었다. FSH pulse 분비는 3그룹에서 모두 높은 빈도로 유지되었고, FSH surge는 LH surge와 같은 시간대에서 난포기 그룹에서만 확인되었다. 본 연구의 결과는 FSH pulse는 LH pulse에서 보이는 progesterone에 의한 억제 효과와 다르게 나타났으며, 이러한 결과는 FSH 분비 조절에 있어서 LH 분비와 다른 기전 및 요소들이 관여하는 것으로 판단되었다.

• 대한한의학방제학회지
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• 제20권1호
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• pp.25-40
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• 2012

The purpose of this study explain the experimental effects of Guizhishaoyaozhimu-Tang (桂枝芍藥知母湯) that have clinical efficacy in rheumatoid Arthritis. Materials of present study were Guizhishaoyaozhimu-Tang freeze dried powder (GSZT), Sprague-dawley rats (300 g or so, male), various kinds of needing experimental studis. In order to study the therapeutic effects of GSZT, this Prescription (GSZT 500 mg/kg, 1,000 mg/kg) were administered per oral to the rats with the arthritis induced by Freund's complete adjuvant ($0.2m{\ell}/kg$), several experimental items were measured and compared each other ; that is body weight, rate of edema, analgesic effect by hot plate method, WBC, total protein, TNF-${\alpha}$, IL-10 and expression and localization of H&E, COX-2 staining in synovial tissues from rat with rheumatoid arthritis by immunohistochemical staining using polyclonal COX-2 antibodies. Rats were divided into four groups. Normal group was not treated with Freund's complete adjuvant and treated with DDW 1.0 $m{\ell}$, Control group was treated with Freund's complete adjuvant 0.2 $m{\ell}/kg$ and DDW 1.0 $m{\ell}$, Sample A group was treated with Freund's complete adjuvant 0.2 $m{\ell}/kg$ and GSZT (500 $mg/m{\ell}$) $1.0m{\ell}$, Sample B group was treated with Freund's complete adjuvant 0.2 $m{\ell}/kg$ and GSZT (1,000 $mg/m{\ell}$) 1.0 $m{\ell}$. 0 was day that did not start experiment, 14 was day that confirmed rheumatism induced by Freund's complete adjuvant, 28 was day that completed experiment. The following results were obtained in this study ; Sample A group was increased in body weight, escape time and paw licking time statistical significance compared with Control group, and were decreased in edema, WBC, total protein, TNF-${\alpha}$ with statistical significance compared with Control group. Sample B group was increased in escape time with statistical significance compared with Control group, and were decreased in edema, WBC, total protein with statistical significance compared with Control group. Sample A and Sample B groups were increased in IL-10 compared with Control group, and Sample B group was decreased in TNF-${\alpha}$ compared with Control group. And, Control, Sample A and Sample B groups were showed considerable reduction of positive expression in comparison to Normal group. Especially, Sample B group was most significantly reduction of positive expression than the other groups. From above results, I suggest that GuizhiShaoyaoZhimu-Tang can be used for curing rheumatoid arthritis.

• 대한지역사회영양학회지
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• 제10권6호
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• pp.795-804
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• 2005

The purpose of this study was to develop of nutritional education activities and effect evaluation in related curriculums for all Dongbu Elementary School children in Jinhae by the teacher in charge. This educational purpose was to build a desirable dietary behavior for optimal growth and health in elementary school children. The educational program contents were developed according to 1) selection of content related curriculums 2) analysis of contents related on dietary habits by grade 3) preparation teaching plans to build desirable dietary habits 4) development of teaching manual by turns. Twelve hours of nutrition education at all school classes were done from March 2 to December 10 2004 in Dongbu Elementary School in Jinhae, Gyeongnam. The education effects were evaluated through the questionnaire surveys before and after the education and their comparative analysis. The results of this study were summarized as follows : Forty percent of the underweight group, $22.8\%$ of the normal group, $42.2\%$ of the obese group had the wrong perceptions on their body figures, but after nutrition education $80.5\%$ of the underweight group, $94.3\%$ of the normal group, $97.9\%$ of the obese group gleaned the correct perceptions on their body figures (p < 0.001). As the effects of the education, the subjects who exercise more than 3 times in a week increased in all groups (p < 0.01-0.001), notably in the obese group. Meal regularity (p < 0.001) , skipping meals (p < 0.001), eating rate and snack selection patterns (p < 0.01-p < 0.001) also improved by nutrition education. We could also observe the effects of the nutrition education through the affirmative statements which appeared in their dietary records. These results showed a possibility of nutrition education activities in related curriculums to improve in dietary habits of school children. Next year, we will start with the system of nutrition teachers in elementary school, but nutrition teacher cannot undertake the task of teaching and food service management alone. Because of that, we intend to develop this program as an alternative proposal for the nutrition education in elementary schools. (Korean J Community Nutrition 10(6) $795\∼804$, 2005)