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Thymectomy in Patients with Myasthenia Gravis (흉선절제로 치료한 중증 근무력증)

  • 조광현
    • Journal of Chest Surgery
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    • v.18 no.4
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    • pp.872-880
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    • 1985
  • Myasthenia gravis is a neuromuscular transmission disorder characterized by fatigue and weakness of voluntary muscles. Although the pathogenesis is known as reduction of available acetylcholine receptors at neuromuscular junctions by autoimmune attack, the thymic role in myasthenia gravis is still unclear and under investigation. But thymectomy in the management of myasthenia gravis has become increasingly important since the first successful operation with remission of symptoms in 1939 by Blalock. From January 1983 to June 1985, authors performed 17 thymectomies for patients with myasthenia gravis. Among them, 12 patients were free from thymoma [Croup A] and 5 were coupled with thymoma [Group B]. The results were as follows: 1] Sex distribution was 11 females and 6 males. Mean age of the patients was 32.2 year old. Sex and age distribution by the Group A and B are shown Table 1. 2] Clinical manifestations of ocular symptoms were seen in 5 patients [88.2%], extremity weakness in 13 patients, bulbar weakness in 12 patients and dyspnea in 6 patients. According to the Osserman`s classification, 5 patients were in group IIA, 6 in IIB and 6 in IIC. 3] Pre-operatively, all patients were positive response to the anti-cholinesterase test and 12 patients [92.3%] revealed positive findings in electromyography [EMC] which was done in 13 patients. 4] The postoperative complications were respiratory distress in 3 patients, myasthenic crisis in 2 patients and wound disruption in one patients. 5] Pathologic examination of the thymus showed hyperplasia in 10 patients [90%] and thymoma in 5 patients, of which 4 were mixed type with invasion to the adjacent tissues and one lymphocytic type without invasion. Normal thymus was noticed in only 2 patients. 6] In postoperative evaluations, among the 12 patients c free from thymoma [Group A], complete remission of symptoms was noticed in 3 patients and improvement in 7 patients. But among the 5 patients coupled with thymoma [Group B], only one patients showed improvement [Table 8]. Therefore, remission and clinical improvement were noticed in 11 patients [64.7%] of the all and complete remission was noticed in 3 patients [17.6%].

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A Clinical Study of Patent Ductus Arteriosus (동맥관개존증의 임상적 고찰)

  • 이선희
    • Journal of Chest Surgery
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    • v.21 no.4
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    • pp.672-680
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    • 1988
  • Munro is generally considered the first person to have demonstrated, in 1888, in an infant cadaver, the feasibility of dissection and ligation of a persistently patent ductus arteriosus. In august, 1938, Robert Gross reported first successful division and suture of the patent ductus of 7 year old girl. Interruption of a ductus is one of the most satisfactory and curative operations in the field of surgery for congenital heart disease. Seventy-eight consecutive cases of closure of patent ductus arteriosus were operated from June 1980 to June 1988 in the department of thoracic and cardiovascular surgery in Maryknoll Hospital. Retrospective clinical analysis of the patients were 1. There were 24 males, 54 females. 2. The age range of the patients were from 7 months to 32 years with the mean age 9.8 years. 3. Chief complaints of the patients were frequent URI[70.5%], dyspnea on exertion[36.9%], palpitation[10.3%], but 15 patients[19.2%] had no subjective symptoms. 4. Continuous machinery murmur could be heard at the 2nd or 3rd intercostal space on the left sternal border in 66 patients[84.6%]. The other 12 patients made systolic murmur. 5. Radiographic findings of the Chest P-A were cardiac enlargement in 55 patients[70%], enlargement of pulmonary conus and/or increasing density of pulmonary vascularity in 68 patients[87%]. 6. Electrocardiographic findings of the patients were within normal limit in 23 patients[36%], LVH in 38 patients[48.7%], RVH in 7 patients[9%], biventricular hypertrophy in 5 patients[6%]. 7. Cardiac catheterization performed in 62 patients. Mean Qp/Qs=2.5, mean pulmonary arterial pressure=45 mmHg. 8. 73 patients were operated through left posterolateral thoracotomy: Closure of the ductus by ligation in 64 cases, division with suture in 6 cases, and division with aortopatch in 3 cases. Ligation through median sternotomy under cardiopulmonary bypass were 5 cases. 9. There was no death associated with operation, but one case was experienced with intraoperative tearing of ductus resulting in massive bleeding. The other complications were transient hoarseness in 2 patients, chylothorax in 2 patients.

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A Study on Dissolve and Remove Analysis of Pollutants in Drinking Water by Suspected Cancer Causing Organic Chemicals using AOPs (Advanced Oxidation Processes) & M/F Hybird Process (고도산화와 정밀여과막 혼성공정을 이용한 먹는 물에 존재하는 발암원인으로 의심되는 유기화학성분의 분해 및 제거분석에 관한 연구)

  • An, Tai-Young;Park, Mi-young;Hur, Jang-hyun;Jun, Sang-ho;Han, Mi-Ae;An, Yoon-Hee
    • Journal of Korean Society on Water Environment
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    • v.23 no.2
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    • pp.193-200
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    • 2007
  • The AOPs research defined by creating a sufficient amount of OH radicals from the dissolution of organic materials through photoxidation and research for a complete elimination of residual organic materials by membrane are actively ongoing. This research focuses on the hybrid processing of AOPs and M/F membrane to dissolve and eliminate organic chemicals in drinking water which are suspected of carcinogens. For this purpose, underground water was used as a source of drinking water for the hybrid processing of AOPs oxidation and M/F membrane, and a pilot plant test device was installed indoor. Carcinogenic chemicals of VOCs and pesticide were artificially mixed with the drinking water, which was then diluted close to natural water in order to examine treatment efficiency and draw optimal operation conditions. The samples used for this experiment include four chemicals phenol, chloroform, in VOCs and parathion, carbaryl in pesticide. As a result of the experiments conducted with simple, and compound solutions, the conditions to sufficiently dissolve and eliminate carcinogenic chemicals from the hybrid processing of where carcinogens were artificially added are : (hydrogen peroxide) prescribed solution 100 mg/L under pH 5.5~6.0, and the temperature $12{\sim}16^{\circ}C$, at the normal temperature and pressure. $d-O_3$ volume of 5.0 ppm and above and 30-40 minutes of reaction time are most appropriate and using MF/UF for membrane was ideal.

Effects of Cervi Pontotrichum cornu and Carthami semen on the Experimental Osteoporosis Induced by Ovariectomy in Rats (녹각(鹿角)과 홍화자(紅花子)가 난소적출에 의한 실험적 흰쥐 골다공증 모델에 미치는 영향)

  • Yook, Tae-Han;Bae, Jin-Seoung;Kim, Yeung-Joo;Kim, Dae-Keun;Jung, Il-Kook;Lee, Chang-Hyun
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.20 no.5
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    • pp.1226-1232
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    • 2006
  • This study was carried out to investigate the effects of Cervi Pontotrichum cornu and Carthami semen on the serum osteocalcin level, bone mineral density, bone trabecular area and cortical thickness index in ovariectomized rats. Femal Sprague-Dawley rats were divided into 5 groups. Non-ovariectomized groups were divided into commertial diet fed(normal group) and calcium free basal diet fed(sham operation group). Ovariectomized groups were divided into 3groups, calcium free basal diet fed group(control group or ovariectomized group), 10% Cervi Pontotrichum cornu supplemented diet fed group and 10% Carthami semen supplemented diet fed group. After 4 weeks diet fed, serum osteocalcin level, bone mineral density, bone trabecular areas and cortical thickness index were analyzed. The bone mineral density and bone trabeculae area were significantly increased by Cervi Pontotrichum cornu and Carthami semen supplemented diet fed groups. The osteocalcin level was significantly decreased by Cervi Pontotrichum cornu and Carthami semen supplemented diet fed groups. The trabecular area(%) in epiphysis of tibia was significantly increased by Cervi Pontotrichum cornu and Carthami semen supplemented diet fed groups. The cortical thickness index in distal diaphysis of tibia was significantly increased by Cervi Pontotrichum cornu and Carthami semen supplemented diet fed groups. the alkaline phosphatase level was significantly decreased by Cervi Pontotrichum cornu and Carthami semen supplemented diet fed groups. These results suggest that Cervi Pontotrichum cornu and Carthami semen might have inhibitory effects on osteoporosis by increasing bone mineral density and accerelating bone formation in ovariectomized rats.

Design and implementation of a connectivity analyzer for the hybrid vehicular network (하이브리드 차량 네트워크를 위한 연결성 분석기의 설계 및 구현)

  • Lee, Junh-Hoon;Kim, Cheol-Min;Kwon, Sang-Cheol
    • Journal of Korea Spatial Information System Society
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    • v.10 no.3
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    • pp.45-54
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    • 2008
  • This paper designs and Implements a connectivity analyzer for the hybrid vehicular network based on the real-life movement history data achieved from the Taxi telematics system currently in operation, aiming at providing a useful guideline and information to build a telematics network. The simulator traces the location of each vehicle, sets the vehicle type, either gateway or normal, decides whether it can be connected to a mobile gateway, keeps track of status of the vehicle, and calculates the duration of disconnected state. With this analysis considering the transmission range and gateway ratio, we can decide the cost-effective number of mobile gateways having both cellular and ad-hoc network interfaces, and buffer space requirement based on the measured disconnection time and message generation ratio.

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Groin flap and Neurovascular island flap for Reconstruction of the Thumb (서혜부 피판과 신경혈관 도서형 피판을 이용한 무지 재건술)

  • Jin, Jin-Woo;Kim, Chong-Kwan;Park, Chan-Wan;Lee, Young-Ho;Kwak, Wan-Sub;Jung, Sung-Weon
    • Archives of Reconstructive Microsurgery
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    • v.14 no.2
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    • pp.152-156
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    • 2005
  • Purpose: We reconstructed the thumb with groin flap combined with secondary heterodigital neurovascular island flap and report our 6 cases. Materials and Methods: Between March 2003 and August 2004, 6 degloving thumbs or amputation of thumbs were reconstructed with groin flap combined with secondary heterodigital neurovascular island flap. There ware 4 men and 2 women, and mean age was 42.2 years. The following parameters were evaluated. Results: Recipient thumb was no limitation of apposition. but flexion contracture of interphalangeal joint was about 10 degree in two cases. Average grip power were 80% and average pinch power were 70% that of the normal thumb. The two point discrimination was average 10.5 mm and double sensibility in 2 cases. 2 patients have cold intolerance. Neuroma formation was not made. Cosmetic results as judged by patients were that 4 cases are good and 2 cases are fair. Conclusion: If massive skin defect after degloving thumb or amputation of thumb are present, we consider the numerous methods for reconstruction of thumb. This surgical procedure is good methods because of it's pliability, sensation, satisfactory functional results but major disadvantage are the staged operation and cosmetic effect of the absence of thumb nail.

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The maneuvering characteristics of the research vessel NARA equipped with the azimuth thruster system (Azimuth thruster 시스템을 장착한 나라호의 조종성)

  • KIM, Jung-Chang;KANG, Il-Kwon;LEE, Jun-Ho;HAM, Sang-Jun;PARK, Chi-Wan;KIM, Su-Hyeng
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.53 no.3
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    • pp.276-285
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    • 2017
  • The research vessel NARA equipped with an azimuth thruster system was built in 2015. There are few vessels with this propulsion system in Korea. This vessel has two modes such as the normal for maneuvering and the power for investigation, and the other two modes as one axis and two axes on the operating. This type of vessels does not seem to have a clear grasp of the maneuvering character in comparison with the vessel with a conventional propulsion system. So the authors carried out the sea test for the turning, the zigzag and the inclination, and the results are as follows. In turning test, the case of using the two axes mode is much better than the case of using the one axis mode for the elements of turning, such as advance, transfer, tactical diameter and final diameter, but turning hard over the rudder in full speed is very vulnerable to capsize in both modes. In zigzag test, the yaw quicking responsibility index, T is very large excessively, which means a bad counter maneuvering ability, so an operator has to keep in mind that in turning operation. If necessary to avoid collision at head on situation, it may be a more effective method to use the crash astern stop than the turning according to the conditions and circumstances for the shortest stopping distance is very short.

A Study on the Customer Voltage Characteristic Based on the Test Devices for PV Systems (태양광전원 계통연계 시험장치에 의한 수용가전압 특성에 관한 연구)

  • Park, Hyeon-Seok;Son, Joon-Ho;Ji, Seong-Ho;Rho, Dae-Seok
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.11 no.11
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    • pp.4529-4536
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    • 2010
  • This paper develops an interconnection test devices for photovoltaic(PV) systems composed of distribution system simulator, PV systems simulator and control and monitoring systems using the LabVIEW S/W, and simulates the customer voltage characteristics considering the 3 parameters on the introduction capacity for PV systems, system configuration and load factor. This paper also proposes a new calculation algorithm for voltage profile to make a comparison between calculation values and test device values. The results show that the test results for the normal operation characteristics of PV systems is very practical and effective.

Usefulness of $^{11}C-Methyl-L-and$ D-Methionine PET in Gliomas : with Special Attention to Recurrence

  • Cho, Won-Sang;Kim, Chi-Heon;Kim, Jeong-Eun;Chung, June-Key;Paek, Sun-Ha;Jung, Hee-Won
    • Journal of Korean Neurosurgical Society
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    • v.39 no.3
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    • pp.176-182
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    • 2006
  • Objective : This study concernes the usefulness of $^{11}C-methyl-L-and$ D-methionine[Met]-positron emission tomography[PET] for glioma grading and detection of recurrence in gliomas, compared with fluorine-18, 2-fluoro-deoxyglucose[FDG]-PET. Methods : Eighty patients underwent Met-PET study for evaluation of glioma : 37 astrocytomas [WHO grade II, 3; III, 8; IV, 26]. 27 oligodendrogliomas [WHO grade II, 16; III, 11]. and 12 suspicious recurrent gliomas. All images were taken within 2 weeks before operation. For suspicious recurrent cases on magnetic resonance images, both FDG-PET and Met-PET were performed. Results : In astrocytoma, Mean maximum standard uptake value[SUV] of region of interest[ROI] was not different between WHO grades [p=0.108]. but ROI/normal contralateral tissue SUV [T/N] ratio was statistically different between WHO grades [p=0.002]. T/N ratio was more closely related to visual scale than maximum SUV of ROI [p<0.001 and p=0.107 respectively]. In oligodendroglioma, there was no statistical difference between WHO grades in view of maximum SUV and T/N ratio. For recurrent gliomas, sensitivity of FDG-PET and Met-PET was 25% and 100%, while specificity of FDG-PET and Met-PET were 100% and 80%, respectively. Conclusion : Met-PET might be an appropriate tool for tumor grading in astrocytoma and be more sensitive for detection of recurrence in gliomas than FDG-PET.

An Infrared Communication Module for the Enhancement of Hearing Aids (보청기 성능 향상을 위한 적외선 통신 모듈)

  • Park, Seong Mo
    • Smart Media Journal
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    • v.7 no.3
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    • pp.29-34
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    • 2018
  • This paper presents a study on adapting optical communication technology using infrared ray for the enhancement of hearing aids in noisy environment. The transmitter module containing microphone and infrared ray-emitting diode converts audio signal to infrared optical signal and sends it out in the air. The receiver module located in a distance receives the infrared signal, converts it to electrical signal, and transfers it to an input of a digital hearing aid. Especially, the receiver module needs to be small, low voltage, and consume low power since it will be attached to hearing aids. Experiments with applying infrared communication technology of digital modulation method and analog non-modulation method show that the analog non-modulation method is adequate for infrared communication of approximately 5m distance indoor. Prototypes of transmitter module and receiver module were manufactured, and internal parameters of the digital hearing aid were adjusted to confirm normal transmit-receive operation of audio signals.