• Journal of Chest Surgery
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• 제10권2호
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• pp.299-314
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• 1977

Clinical experience on 16 cases of open heart surgery under the extracorporeal circulation with mild or moderate hypothermia and partial hemodilution technique at the National Medical Center during the period from June 1976 to October 1977. Nine of sixteen were congenital heart disease and seven were acquired heart disease. The age of the patient ranged between 6 and 48 years. The body weight varied from 18.5kg to 60kg and body surface area 0. 79-1.70m2. The average priming volume of pump oxygenator was 2080 ml, which was consisted fresh ACD blood, buffered Hartmann`s solution, Mannitol, 50% dextrose in water and Vit. C. The average hemodilution rate was 27%. The average flow 2.3 L/min/m2 or 80 ml/min and the duration of perfusion varied from 31 min to 270 min with average of 107 min. The perfusion was carried out under the mild or moderate hypothermia using core cooling alone in 10 cases, core cooling and local myocardial cooling with $0-4^{\circ}C$ physiologic saline in 2 cases. From a hemodynamic point of view, the blood pressure dropped down around 80 mmHg after the initiation of perfusion follwed by increase to safety level and stable during the perfusion. The central venous pressure remained within normal limits. In most cases, hemoglobin and hematocrit decreased during and after the perfusion. Hemogiobin level was decreased, average of 20.6 %, hematocrit 18.6%, pletelets 55% postoperatively. Plasma hemoglobin increased moderately, from preperfusion average valve of 7.79 mg % to post-perfusion value of 54.7 mg %. Electrolytes changes during cardiopulmonary bypass showed definite hypokalemia but changes of Na, Ca were not definite. Arterial blood gas analysis during cardiopulmonary bypass suggested that the metabolic acidosis which was accompanied by respiratory alkalosis which was corrected postoperatively. As the opera tive complication, transient hemoglobinuria in 4 cases and neurological signs in 2 cases were all cured. There were 2 death cases and operative mortality rate was 12.5%.

• 한국콘텐츠학회논문지
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• 제15권9호
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• pp.329-341
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• 2015

본 연구의 목적은 간호대학 신입생들의 의사소통 스타일에 대한 주관성 유형을 파악하고 유형별 특성을 탐구하기 위한 것이며 연구방법은 Q 방법론을 적용하였다. 간호대학 신입생으로 구성된 P 표본 50명을 대상으로 의사소통 스타일에 대한 Q 표본 55개의 진술문을 11점 척도 분포도에 분류하게 하였다. 자료 수집은 2015년 5월부터 6월까지 진행되었고 수집된 자료는 PC-QUANL 프로그램으로 분석하였다. 연구결과 의사소통 스타일은 '개방적 교류 촉진형', '타인배려 경청형', '비판예민 긴장형', '교류회피 관찰형'으로 추출되었다. 개방적 교류 촉진형은 언어적, 비언어적 표현을 능숙하게 사용하여 개방적으로 자아를 노출하고 교류를 촉진하는 유형이다. 타인배려 경청형은 자신보다는 타인의 입장을 먼저 생각하여 신중하게 의사소통을 하는 스타일이다. 비판예민 긴장형은 비판에 예민하고 긴장하며 산만한 스타일로 친밀한 교류가 어려운 유형이다. 교류회피 관찰형은 자기를 노출하지 않고, 타인을 관찰하면서 상호교류에 무관심한 방관자 스타일이다. 본 연구결과는 향후 간호대학 신입생을 위한 의사소통 교육프로그램 개발에 활용될 수 있을 것으로 기대한다.

• 컴퓨터교육학회논문지
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• 제13권6호
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• pp.91-98
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• 2010

NAC(Network Access Control)는 운영체제 보안 패치 미 적용 혹은 AV(Anti-Virus)미설치 컴퓨터 등 웜의 공격대상이 되어 내부망에 바이러스를 유포하는 엔드 포인트 사용자 보안에 대한 솔루션으로 개발되었다. 현재 시장에 상용화된 NAC 제품들이 경우 연결 전 보안기능(pre-connect)기술들은 많이 발전되어 있으나, 정상적인 인증을 통해 연결된 이후에 발생하는 위협을 탐지하는 위협 관리 기능(post-connect)이 대체적으로 부족한 상태이며, 이에 따라 Zero-day 공격, 악성코드 감염 등으로 NAC 사용자들이 지속적으로 피해를 입고 있는 상황이다. 본 논문에서는 이러한 post-connect단계에서의 문제점을 해결하고자 기존에 사용되던 단말에 대한 인증과 정책 위반 여부 검사 외에 각 단말이 발생시키는 트래픽 정보와 Agent를 통해 획득한 각 단말의 정보, 그리고 Network Scanner에서 획득한 Open Port와 네트워크 구성 변경 정보를 활용하여 정상 Behavior profile을 생성하고 이를 기반으로 악성코드 감염 시스템을 탐지하는 시스템을 제안한다.

• 정보보호학회논문지
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• 제26권1호
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• pp.169-176
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• 2016

안드로이드 플랫폼은 사용자 친화적으로 설계되어 있다. 하지만 이러한 친화적 설계는 취약점이 쉽게 발생할 수 있고, 일반적인 사용자는 쉽게 탐지가 어렵다는 단점을 가지고 있다. 따라서, 본 논문에서는 안드로이드 어플리케이션 분석을 위한 유명한 오픈 소스 분석 도구를 설명하고, 현재 구글의 권한 그룹에 대한 정책의 위험성을 설명한 후 공격자의 권한 상승에 대한 위험을 완화하기 위한 기법을 제안한다. 또한, 21,064의 악성코드 샘플을 조사하여 제안한 기술이 안전하지 않은 응용 프로그램 업데이트 탐지에 대한 증명을 하였을 뿐 아니라 보안 위협에 대한 인식을 고취시키고자 하였다.

• Structural Engineering and Mechanics
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• 제42권1호
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• pp.121-129
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• 2012

All contemporary seismic Codes have adopted smooth design acceleration response spectra, which have derived by statistical analysis of many elastic response spectra of natural accelerograms. The above smooth design spectra are characterized by two main branches, an horizontal branch that is 2.5 times higher than the peak ground acceleration, and a declining parabolic branch. According to Eurocode EN/1998, the period range of the horizontal, flat branch is extended from 0.1 s, for rock soils, up to 0.8 s for softer ones. However, from many natural recorded accelerograms of important earthquakes, the real spectral amplification factor appears to be much higher than 2.5 and this means that the spectrum leads to an unsafe seismic design of the structures. This point is an issue open to question and it is the object of the present study. In the present paper, the spectral amplification factor of the smooth design acceleration spectra is re-calculated on the grounds of a known "reliability index" for a desired probability of exceedance. As a pilot scheme, the seismic area of Greece is chosen, as it is the most seismically hazardous area in Europe. The accelerograms of the 82 most important earthquakes, which have occurred in Greece during the last 38 years, are used. The soil categories are taken into account according to EN/1998. The results that have been concluded from these data are compared with the results obtained from other strong earthquakes reported in the World literature.

• 한국추진공학회:학술대회논문집
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• 한국추진공학회 2017년도 제48회 춘계학술대회논문집
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• pp.218-223
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• 2017

본 논문은 75톤급 액체로켓엔진의 상태진단을 위해 칼만 필터를 이용한 고장진단 연구를 수행하였다. 칼만 필터 설계를 위해 75톤급 액체로켓엔진 비선형 시뮬레이션 모델을 공칭 작동점에서 선형화하였으며, 정상 모델의 상태량 변수 4가지를 이용하여 측정값과 추정값 비교를 통해 칼만 필터의 성능을 확인하였다. 이를 이용한 고장진단 알고리즘의 성능을 확인하기 위하여 터보펌프 고장을 모사하였으며 정상 모델의 잔차 변화를 비교하여 칼만 필터를 이용한 고장진단이 가능함을 확인하였다.

• BMB Reports
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• 제40권5호
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• pp.715-722
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• 2007

A new full-length cDNA encoding hyoscyamine $6\beta$-hydroxylase (designated as aah6h, GenBank Accession No. EF187826), which catalyzes the last committed step in the scopolamine biosynthetic pathway, was isolated from young roots of Anisodus acutangulus by rapid amplification of cDNA ends (RACE) for the first time. The full-length cDNA of aah6h was 1380 bp and contained a 1035 bp open reading frame (ORF) encoding a deduced protein of 344 amino acid residues. The deduced protein had an isoelectric point (pI) of 5.09 and a calculated molecular mass of about 38.7 kDa. Sequence analyses showed that AaH6H had high homology with other H6Hs isolated from some scopolamine-producing plants such as Hyoscyamus niger, Datura metel and Atropa belladonna etc. Bioinformatics analyses results indicated AaH6H belongs to 2-oxoglutarate-dependent dioxygenase superfamily. Phylogenetic tree analysis showed that AaH6H had closest relationship with H6H from A. tanguticus. Southern hybridization analysis of the genomic DNA revealed that aah6h belonged to a multi-copy gene family. Tissue expression pattern analysis firstly founded that aah6h expressed in all the tested tissues including roots, stems and leaves and indicated that aah6h was a constitutive-expression gene, which was the first reported tissue-independent h6h gene compared to other known h6h genes.

• 한국패류학회지
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• 제32권4호
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• pp.241-247
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• 2016

Macrophage Migration Inhibitory Factor (MIF) are well-defined role as unique cytokine and critical mediator in acute and chronic inflammatory diseases, autoimmune diseases. In this study, we isolated and characterized a full-length of MIF cDNA from the abalone (Haliotis discus hannai). The full-length cDNA of abMIF was of 1264 bp, consisting of a 5'-terminal UTR of 143 bp, an open reading frame of 360 bp and a 3-terminal UTR of 761 bp. The abalone MIF cDNA encodes a 119-amino acid polypeptide with a calculated molecular mass of 13.4 kDa and isoelectric point of 9.07. Multiple alignments and phylogenetic analysis with the deduced abalone MIF protein and showed strong homology with disk abalone (Haliotis discusdiscus). The deduced amino acid sequence of abMIF exhibited homology with other reported MIFs, such as 80%, with that of other disk abalone H. discus discus MIF gene. Quantitative real-time PCR (qRT-PCR) analysis indicated that abMIF was highly expression observed in hapatopacreas, intestine, foot, and gonad of normal conditioned abalone. Even though AbMIF mRNA level in hemocytes was low under the normal condition, it was sharply up-regulated and reached the maximum at 6 h post-infection with Vibrio parahaemolyticus, and then decreased at 24 h post-infection. This result indicates that abMIF plays an important role in responding in the innate immune system.

• 동서간호학연구지
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• 제3권1호
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• pp.7-16
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• 1998

This paper reviewed the concept of the energy flow in east and west. The differences in the views of the energy flow between oriental and western thought were compaired according to the ontological point of view. Human body take up energy and material on open system which maintains homeostasis. Human and environment are continuously interacting in a state of co-existence. Human has energy field called "aura" and seven chakra in energy outflow moving came as meridian. Qi is an invisible cosmic energy helping the fundamental human activity and changes. The basic action of Qi is helping the human growth and development, maintain the body temperature and preventing the intrusion of microorganism. In the normal healthy organism, all are maintained in balance and in a continuous circulation of Qi, while illness is the result of the disturbed Qi flow in the aspect of Qi-theory. Although there are differences between oriental and western medicine in approaches to clients, the basic point of view and philosophy have many similarities on fundamental level. An understanding of the basic thought of energy flow and oriental concept of energy flow implies a more comprehensive meaning than the perspective of unitary transformation discussed in modern western thought of energy flow. Now we should avoid narrow view of energy concept and regard energy flow as an integrated concept with Korean culture. Regarding Qi-theory which provides a comprehensive and humanistic and ethical foundation for nursing philisophy through this overview, it is hoped that a contribution will be made to the development of nursing intervention which is suitable to Korean context.

• 한국압력기기공학회 논문집
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• 제9권1호
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• pp.15-19
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• 2013

The auxiliary feedwater is an important to remove the heat from the reactor core when the main feedwater system is unavailable. In most initiating events in Probabilistic Safety Assessment(PSA), the operaton of this system is required to mitigate the accidents. For one of domestic nuclear power plants, a design change of a turbine-driven auxiliary feedwater pump(TD-AFWP), pipe, and valves in the auxiliary system is implemented due to the aging related deterioration by long time operation. This change includes the replacement of the TD-AFWP, the relocation of some valves for improving the system availability, a new cross-tie line, and the installation of manual valves for maintenance. The design modification affects the PSA because the system is critical to mitigate the accidents. In this paper, the safety effect of the change of the auxiliary feedwater system is assessed with regard to the PSA view point. The results demonstrate that this change can supply the auxiliary feedwater from the TD-AFWP in the accident with the motor-driven auxiliary feedwater pump(MD-AFWP) unavailable due to test or maintenance. In addition, the change of MOV's normal position from "close" to "open" can deliver the water to steam generator in the loss of offsite power(LOOP) event. Therefore, it is confirmed that the design change of the auxiliary feedwater system reduces the total core damage frequency(CDF).