• Title/Summary/Keyword: Normal Aging

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Glycation Inhibitory and Antioxidative Activities of Ergothioneine (에르고티오네인의 당화 억제 및 항산화 활성에 관한 연구)

  • Bae, Jun-Tae;Lee, Chung-Hee;Lee, Geun-Soo;Kim, Jin-Hwa;Hong, Jin-Tae
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.45 no.2
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    • pp.151-159
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    • 2019
  • Ergothioneine has been known as an excellent antioxidant and a cellular protector against oxidative damage in vivo. In the present study, ergothioneine was demonstrated to possess antioxidant and anti-glycation activities. The radical scavenging activity of ergothioneine enhanced the viability of human dermal fibroblasts (HDFs) exposed to ultraviolet (UV) light. The UVA irradiation increased the proportion of senescence-associated ${\beta}$-galactosidase (SA-${\beta}$-gal) positive cells in comparison with the normal control group. The treatment of UVA-irradiated HDFs with ergothioneine decreased the level of SA-b-gal (by approximately 45% at an ergothioneine concentration of $400{\mu}M$) compared with the UVA-irradiated HDFs. We also found that ergothioneine inhibited production of glyceraldehyde-derived advanced glycation endproducts (AGEs) in a concentration-dependent manner. The ergothioneine educed carboxymethyl-lysine (CML) expression in comparison to the glyoxal treatment. In addition, in the Western blot analysis, treatment of glyoxal-stimulated HDFs with ergothioneine resulted in a dose-dependent decrease in the expression level of the receptor for AGE (RAGE). These results suggest that ergothioneine may have potent anti-aging effects and could be used as a cosmetic material against cellular accumulation of AGEs.

Characteristics of Narrative Writing in Normal Aging: Story Grammar and Syntactic Structure (노년층의 글쓰기 특성 -이야기문법과 구문구조)

  • Kim, Hyeon Ah;Won, Sae Rom;Lee, Bo Eun;Yoon, Ji Hye
    • 재활복지
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    • v.21 no.1
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    • pp.193-212
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    • 2017
  • The elderly often produce irrelevant speech and get off-topic more easily than the young; the former also has difficulty generating fewer syntactic structures and makes errors of grammatical morphemes. In particular, the elderly might have more difficulty writing since it requires more complex cognitive processes than storytelling. The participants in this study were 32 young people and 32 older people. They were asked to write a short story of Korean fairy tale('Heungbu Nolbu'). The data was analyzed in narrative composition and syntactic structures. The study revealed the following: First, in composition aspects, the elderly group showed significantly lower total number of story grammar and episodes. In addition, the elderly produced more off topic statements. Second, in syntactic aspects, although there was no significant difference in the number of producing complex sentences between two groups, the elderly group generated more inadequate cohesive devices and used fewer relative and adverbial clauses. These findings suggest that the elderly have a tendency to perform tasks by producing more off-topic statements and shows decreasing coherence by using lower number of relative and adverbial clauses. However, this study also uncovers that the elderly were able to write more complex and longer sentences using visual feedback.

Analysis of the Relationship between Macpa Stress Index and Korean Job Stress Level - Focusing on Subway Construction Workers (맥파 스트레스와 한국인 직무스트레스의 상관관계 분석 - 도시철도 건설종사자를 대상으로)

  • Chae, Joung Sik;Lee, Yu Jeong;Chang, Seong Rok
    • Journal of the Korean Society of Safety
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    • v.37 no.1
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    • pp.64-69
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    • 2022
  • The study measured a subway construction worker's Macpa stress by Heart Rate Variability measuring instrument and conducted a survey of Korean job stress from subway construction workers. Also, the study analyzed the relationship between Macpa stress index and Korean job stress result and suggested managing stress method for each item. According to National Statistical Office data, the first line subway in Seoul was started to open in 1974. The extended total length is 996 kilometers until 2019. Many aged workers are currently working at subway construction sites due to the avoidance of young workers since the past until now. It means that the elderly has a substantial portion among subway construction workers. The productivity has been adversely affected by health problems due to the aging of workers, job stress due to heavy work, and personal health problems. So, the regulation and policies on job stress health management are being strengthened. The data were measured Macpa stress by machine measuring heart rate variability and conducted Korean job stress survey(shortened) from Sa-sang to Ha-dan line Busan subway construction workers for analyzing the relationship. Independent variable were age, job duration, job position, employment type, working type in this study. Macpa's dependent variable was stress index and Korean job stress survey(shortened)'s dependent variables were job requirements, job autonomy, relationship conflict, job instability, organizational structure, inappropriate compensation, working place culture, and total score. SPSS 12.0 K Statistics Program was used for statistical analysis. Kruskal-wallis test, a nonparametric statistical analysis, was used because the data are difficult to be assumed as normal distribution. As a result, the paper indicated the significant correlation between Macpa stress index and Korean job stress(short version). The elderly workers presented higher Macpa index and higher job stress due to aging and heavy-duty work. The majority workers were daily workers who had unstable working condition and uncertainty about the future. The study suggested a manual that could reduce job stress for subway construction workers and future study deriving management tool through analyzing job stress factor is necessary.

The Health Status according to the Age and BMI of Male Workers in Daegu.Gyeongbuk Region (대구.경북지역 20, 30대 남성 근로자의 연령 및 BMI에 따른 건강상태)

  • Jang, Hyun-Sook;Choi, Ju-Hee
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.36 no.3
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    • pp.318-326
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    • 2007
  • The purpose for this study was to investigate the health status according to the age and BMI by interviewing male workers in their twenties and thirties in the Daegu Gyeongbuk region. The body measurement was assessed by height, weight, BMI, body circumference (waist, hip), waist-hip ratio and body fat mass. The health status has been analyzed and assessed as normal group, health concerned group and health suspected groups. Weight, percent ideal body weight (PIBW), BMI and body circumference (waist, hip) and waist-hip ratio was proven higher according to the order of obese group, overweight group and normal group. Waist-hip ratio was proved to be higher in the thirties group than the twenties. Body fat mass was higher in the obese, overweight and normal groups. In the concerns of health status, the ratio of health concerned group and health suspected group increased according to the increase of BMI. Blood pressure (SBP, DBP) was higher in the obese group than in the normal group and overweight groups, and blood glucose was higher in the thirties than in the twenties. SGOT, SGPT, ${\gamma}-GTP$ has been proven higher in the obese group than in the normal group and overweight group, ${\gamma}-GTP$ was higher in the thirties than in the twenties. Investigating the correlation of the anthropometric characteristics and biochemical characteristics, the heavy weight resulted in heavier BMI, PIBW, body circumference (waist, hip), waist-hip ratio and higher body fat mass. Blood pressure (SBP, DBP), total cholesterol, blood glucose, SGOT, SGPT and ${\gamma}-GTP$ all became higher according to these influences. In conclusion, male workers have to recognize that health status becomes worse and possibilities of chronic disease prevalence rate increases according to aging and the increase of BMI. Accordingly, it is necessary to make an effort to prevent chronic diseases.

Fatigue Crack Growth Behavior of a Continuous Alumina Fiber Reinforced Metal Matrix Composite Materials (알루미나 장섬유 강화 복합금속재의 피로균열성장거동)

  • Doo Hwan, Kim;Lavernia, E.J.;Earthman, J.C.
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.11 no.1
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    • pp.29-36
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    • 1991
  • The effects of heat treatment on fatigue crack growth behavior were studied in continuously reinfored, magnesium-based composite (FP/ZE41A). Following an earlier TEM investigation, specimens were thermally aged to modify the interfacial zone between the alumina fibers and mg alloy matrix. The fatigue crack growth experiments were conducted with specimens having the fiber orientation normal to the crack growth direction(longitudinal) and also specimens with the fibers oriented parallel to the crack growth direction(transverse). A comparision of the fatigue crack growth behavior indicates that aged longitudinal specimens are more resistant to fatigue crack growth than as-fabricated longitudinal specimens. Conversely, as-fabricated transverse specimens are more resistant to fatigue crack growth than aged transverse specimens. SEM observations of fiber pullout and ductile tearing on the fatigue fracture surfaces indicate that the aging weakens the strength of the fiber/matrix interface, giving rise to the observed fatigue crack growth behavior.

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Effect of tractor travelling speed on a tire slip

  • Kim, Yeon Soo;Lee, Sang Dae;Kim, Young Joo;Kim, Yong Joo;Choi, Chang Hyun
    • Korean Journal of Agricultural Science
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    • v.45 no.1
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    • pp.120-127
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    • 2018
  • The rural labor force has gradually been decreasing due to the decrement of the farm population and the increment of the aging population. To solve these problems, it is necessary to develop and study autonomous agricultural machinery. Therefore, analyzing the dynamic behavior of vehicles in an autonomous agricultural environment is important. Until now, most studies on agricultural machinery, especially on ground vehicle dynamics, have been done by field tests. However, these field test methods are time consuming and costly with seasonal restrictions. A research method that can replace existing field test methods by using simulations is needed. In this study, we did basic research analyzing the effect of the travelling speed of a tractor on tire slip using simulation software. A tractor simulation model was developed based on field conditions following a straight path. The simulation was done for three ranges of speed: 20 - 30 km/h (considered the normal travelling speed range), 6 - 8 km/h (considered the plow tillage speed range) and 2 - 4 km/h (considered the rotary tillage speed range). The results of the simulation show that the slip ratio and slip angle values tended to increase as the traveling speed range of the tractor decreased. From the simulation results, it can be concluded that at low tractor speeds, it becomes more difficult to control the vehicle path. In future research, simulations will be done with various work environments such as a curved path as well as with various friction coefficient conditions, and the simulation results will be experimentally verified by applying them to an agricultural tractor.

The State of Housing of the Elderly with Vision Impaired and the Its Impacts on Quality of Life

  • Lee, So Young;Yoo, Sung Eun
    • Architectural research
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    • v.18 no.4
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    • pp.129-136
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    • 2016
  • People have experienced physical problems including vision problems with aging; some are normal and some are abnormal. When they have abnormal and impaired vision, they have a lower level of life satisfaction than their sighted peers. For the elderly with sight loss, well-designed housing could be an important indicator for their quality of life. Housing adjustment and modification could help the elderly cope with sight loss, do daily activities more independently, and lead to better quality of life. The purpose of this study is to investigate housing conditions for the elderly with vision impaired, state of housing adjustment or modifications, and the effects of housing conditions on the wellness of the elderly in Korea. For this study, 18 housing cases were investigated and a total number of 65 visually impaired people aged over 55 participated. Housing condition of those participated was poor. Most observed home hazards are level differences in living areas, obstacles in the hallway, confined space that is not allowed structural modification, swing doors from wardrobe or cabinets, color contrast, poor lightings, and etc. Majority of households participated in this study did not make modification or refurbishments, rather many of them tend to adapt themselves to their residential environments. Older adults living in better housing condition and under less difficult environments are likely to have higher life satisfaction. The effects of housing condition on wellness could be more influential when individual capabilities (e.g. health condition) are weaker. The findings underline that with intervention of individual characteristics, the effects of housing and physical environment on negative outcomes of vision loss would get ameliorated or reduced.

Full mouth rehabilitation using removable partial denture in patient with loss of vertical dimension due to worn dentition (심한 치아 마모로 인해 수직 고경이 상실된 환자에서 국소 의치를 이용한 전악 수복 증례)

  • Shim, Eun-Young;Lee, Na-Young;Kang, Jeong-Kyung
    • The Journal of Korean Academy of Prosthodontics
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    • v.56 no.4
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    • pp.347-353
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    • 2018
  • Gradual attrition is a normal process of aging, but severe attrition causes occlusal disharmony, functional disorder and esthetic problems. The collapse of posterior support may cause attrition of anterior teeth, and loss of occlusal vertical dimension (OVD). And it induces the pathologic change of the TMJ, unaesthetic facial appearance and decreased masticatory function. In this case, 70 year-old male presented with decreased vertical dimension and esthetic problems due to worn dentition. Based on assessment of intraoral findings, diagnostic cast and radiographic examination, full-mouth rehabilitation with increase of OVD was planned. After 10 month follow-up, occlusal stability is maintained and through this procedure, satisfactory outcomes were achieved in esthetic and functional aspects.

The flexural strength Changes by the Low Temperature Degradation of Uncolored zirconia Ceramic for All Ceramic Restoration (전부도재 수복을 위한 무색지르코니아 세라믹의 저온열화에 따른 굴곡강도 변화)

  • Kim, Jung-Sook
    • Journal of Technologic Dentistry
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    • v.31 no.2
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    • pp.39-44
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    • 2009
  • In the orthopedic field which firstly used zirconia as artificial joints, researchers had studied the reasons for collapsing zirconia used as restorative material by accumulated inner cracks in several years and they found out Low Temperature Degradation is one of the reasons. In the dentistry field, it has not been too long since they used zirconia as the cores of all-ceramic restoration; however, the study is needed as prophylactic measure against Low Temperature Degradation which can be caused by saliva wetting the mouth all the time and frictional forces such as bite pressure and masticatory pressure. Artificial aging by autoclaving is used because there are difficulties of testing in the patient's mouth. To study the changes in the material properties, the flexural strength of dental zirconia ceramic is measured before and after the test. The following are the result of the test. 1) The zirconia blocks in the autoclaves at $130^{\circ}C$ and $200^{\circ}C$ are phase-shifted tetragonal to monoclinic by Low Temperature Degradation. 2)The non-autoclaved specimens have the average fractural strength of 1346.4MPa, the specimens autoclaved at $130^{\circ}C$ have 1226.4Mpa and the specimens autoclaved at $200^{\circ}C$ have 1024.1MPa. The tests show that as the temperature increases, the flexural strength tend to decrease and the differences are noticeable(p<0.001). 3)Through the Duncan's post-hoc test, the differences in flexural strength of the 3 groups were listed in order of strength like normal temperature>at $130^{\circ}C$ autoclave low temperature degradation> at $200^{\circ}C$ autoclave low temperature degradation.

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Effects of oral health behavior on remaining teeth in Korean adults older than 45 years with hypertension and diabetes (한국성인의 고혈압, 당뇨 환자의 구강건강행태가 잔존치아 수에 미치는 영향)

  • Lee, Jung-Hwa
    • Journal of Korean society of Dental Hygiene
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    • v.20 no.1
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    • pp.41-51
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    • 2020
  • Objectives: The purpose of this study was to investigate the effects of oral health behaviors of patients with hypertension and diabetic patients on the number of remaining teeth in Korean adults over 45 years of age, furthermore, we also aimed to develop oral health care programs and health promotion for patients with hypertension and diabetes. Methods: Altogether, 1,526 subjects with hypertension and diabetes from the 6th Korean National Health and Nutrition Survey (2013-2015) were analyzed. Results: A multiple logistic regression analysis was performed to determine the effects of oral health behavior and periodontal disease on residual teeth in patients with hypertension and diabetes after adjusting for age. We found 1.53 times the risk of having less than 20 remaining teeth in the group of brushing more than 3 times a day (95% CI: 1.00,2.35, p<0.001), 2.27 times (95% CI: 1.23-4.17, p<0.05) in the group not using the dental floss group 0.05), compared to the group undergoing regular dental check-up (95% CI: 0.93-1.85, p>0.05), compared to the non-smoking group 0.77 times (95% CI: 0.51-1.14, p>0.05), 1.33 times (95% CI: 0.98-1.80, p>0.05) in the drinking group compared to the non-drinking group, in the periodontal disease group, the risk of having less than 20 remaining teeth was 2.19 times higher (95% CI: 1.48-3.24, p>0.001) than in the normal group. Conclusions: As a super-aging society, develops in Korea, the prevalence of hypertension and diabetes will increase gradually. Therefore, an oral health policy should be implemented at the national level for the prevention and treatment of periodontal disease as well as the management of oral health the elderly.